WO2009090330A3 - Use of protein 8c2 for in vitro diagnosis of mycoplasma pneumoniae infections - Google Patents

Use of protein 8c2 for in vitro diagnosis of mycoplasma pneumoniae infections Download PDF

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Publication number
WO2009090330A3
WO2009090330A3 PCT/FR2008/001440 FR2008001440W WO2009090330A3 WO 2009090330 A3 WO2009090330 A3 WO 2009090330A3 FR 2008001440 W FR2008001440 W FR 2008001440W WO 2009090330 A3 WO2009090330 A3 WO 2009090330A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein
mycoplasma pneumoniae
vitro diagnosis
pneumoniae infections
infections
Prior art date
Application number
PCT/FR2008/001440
Other languages
French (fr)
Other versions
WO2009090330A2 (en
Inventor
Camille Cyncynatus
Hélène NUYTTENS
Original Assignee
Ingen Biosciences
UNIVERSITE VICTOR SEGALEN BORDEAUX 2 Etablissement public à caractère scientifique, culturel et professionnel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ingen Biosciences, UNIVERSITE VICTOR SEGALEN BORDEAUX 2 Etablissement public à caractère scientifique, culturel et professionnel filed Critical Ingen Biosciences
Publication of WO2009090330A2 publication Critical patent/WO2009090330A2/en
Publication of WO2009090330A3 publication Critical patent/WO2009090330A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0241Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/30Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56933Mycoplasma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/30Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms

Abstract

The invention relates to the use of the protein 8C2, having the polypeptide sequence ID SEQ N°2, or fragments or variants of said protein, and to the use of sequences coding for said proteins in the field of in vitro diagnosis of a Mycoplasma pneumoniae infection.
PCT/FR2008/001440 2007-10-17 2008-10-14 Use of protein 8c2 for in vitro diagnosis of mycoplasma pneumoniae infections WO2009090330A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0707266 2007-10-17
FR0707266A FR2922648B1 (en) 2007-10-17 2007-10-17 USE OF PROTEIN 8C2 FOR IN VITRO DIAGNOSIS OF MYCOPLASMA PNEUMONIAE INFECTIONS

Publications (2)

Publication Number Publication Date
WO2009090330A2 WO2009090330A2 (en) 2009-07-23
WO2009090330A3 true WO2009090330A3 (en) 2009-10-01

Family

ID=39493621

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2008/001440 WO2009090330A2 (en) 2007-10-17 2008-10-14 Use of protein 8c2 for in vitro diagnosis of mycoplasma pneumoniae infections

Country Status (2)

Country Link
FR (1) FR2922648B1 (en)
WO (1) WO2009090330A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2922648B1 (en) * 2007-10-17 2013-01-18 Abag USE OF PROTEIN 8C2 FOR IN VITRO DIAGNOSIS OF MYCOPLASMA PNEUMONIAE INFECTIONS

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002077183A2 (en) * 2001-03-21 2002-10-03 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
US6617156B1 (en) * 1997-08-15 2003-09-09 Lynn A. Doucette-Stamm Nucleic acid and amino acid sequences relating to Enterococcus faecalis for diagnostics and therapeutics
WO2006103343A1 (en) * 2005-03-29 2006-10-05 Abag S.A. Use of protein 2e9 for in vitro diagnosis of mycoplasma pneumoniae infections
FR2922648A1 (en) * 2007-10-17 2009-04-24 Abag Sa Use of mycoplasma protein 8C2 to assay biological samples for antibodies produced as a result of Mycoplasma pneumoniae infections

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6617156B1 (en) * 1997-08-15 2003-09-09 Lynn A. Doucette-Stamm Nucleic acid and amino acid sequences relating to Enterococcus faecalis for diagnostics and therapeutics
WO2002077183A2 (en) * 2001-03-21 2002-10-03 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
WO2006103343A1 (en) * 2005-03-29 2006-10-05 Abag S.A. Use of protein 2e9 for in vitro diagnosis of mycoplasma pneumoniae infections
FR2922648A1 (en) * 2007-10-17 2009-04-24 Abag Sa Use of mycoplasma protein 8C2 to assay biological samples for antibodies produced as a result of Mycoplasma pneumoniae infections

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DANDEKAR D ET AL: "Re-annotating the Mycoplasma pneumoniae genome sequence: adding value, function and reading frames", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 28, no. 17, 1 January 2000 (2000-01-01), pages 3278 - 3288, XP003008959 *
DATABASE EBI 15 June 2007 (2007-06-15), "http://www.ebi.ac.uk/cgi-bin/epo/epofetch?ABU36288", XP002485161 *
DATABASE EBI 19 June 2003 (2003-06-19), "http://www.ebi.ac.uk/cgi-bin/epo/epofetch?ACA40158", XP002485184 *
DATABASE EBI 22 December 2005 (2005-12-22), "http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+([emblidacc-id:U00089]>embl) [embl-acc:U00089]+-vn+2+-noSession", XP002485189 *
DATABASE EBI 23 January 2007 (2007-01-23), "http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[uniprot-id:FPG_MYCPN] [uniprot-acc:FPG_MYCPN]+-noSession", XP002485190 *
DATABASE Geneseq 22 April 2004 (2004-04-22), XP002537869, Database accession no. GENESEQP:ADH85744 *
HIMMELREICH RALF ET AL: "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 24, no. 22, 1 January 1996 (1996-01-01), pages 4420 - 4449, XP002172064 *
RÄISÄNEN S ET AL.: "Mycoplasma pneumoniae protein involved in the antibody response in human infection.", JOURNAL OF CLINICAL PATHOLOGY, vol. 37, no. 10, October 1984 (1984-10-01), pages 1129 - 1133, XP009101769, ISSN: 0021-9746 *

Also Published As

Publication number Publication date
FR2922648A1 (en) 2009-04-24
WO2009090330A2 (en) 2009-07-23
FR2922648B1 (en) 2013-01-18

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