WO2009078352A1 - Fluid receiving cartridge and utilization of the same - Google Patents

Fluid receiving cartridge and utilization of the same Download PDF

Info

Publication number
WO2009078352A1
WO2009078352A1 PCT/JP2008/072638 JP2008072638W WO2009078352A1 WO 2009078352 A1 WO2009078352 A1 WO 2009078352A1 JP 2008072638 W JP2008072638 W JP 2008072638W WO 2009078352 A1 WO2009078352 A1 WO 2009078352A1
Authority
WO
WIPO (PCT)
Prior art keywords
reaction tank
supplied
liquid receiving
liquid
outside
Prior art date
Application number
PCT/JP2008/072638
Other languages
French (fr)
Japanese (ja)
Inventor
Masahiro Murasato
Kazunari Yamada
Dai Yamamoto
Akinobu Oribe
Kousuke Niwa
Original Assignee
Ngk Insulators, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ngk Insulators, Ltd. filed Critical Ngk Insulators, Ltd.
Priority to US12/747,597 priority Critical patent/US20100276309A1/en
Priority to CN2008801208048A priority patent/CN101896598A/en
Priority to EP08862757A priority patent/EP2241613A4/en
Publication of WO2009078352A1 publication Critical patent/WO2009078352A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/40—Mixers using gas or liquid agitation, e.g. with air supply tubes
    • B01F33/403—Mixers using gas or liquid agitation, e.g. with air supply tubes for mixing liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems

Abstract

Liquid is received in liquid receiving sections (1-15, 17) formed in a first layer (50a) and a second layer (50b) of a cartridge and each having a specific volume determined according to a liquid to be received in the liquid receiving section. A reaction tank is connected to one of flow ports (1a-16a), and, with the reaction tank connected, pressure is applied to a liquid receiving section connected to the flow port to which the reaction tank is connected. This causes outside air to be supplied to that liquid receiving section from an outside-air flow section (21) communicating with the outside, and liquid received in the liquid receiving section is supplied to the reaction tank. Then, the cartridge is rotated to connect another flow port to the reaction tank, and as a result, liquids are supplied to the reaction tank. In this process, the outside air supplied from the outside-air flow section (21) is supplied to the reaction tank via the flow port connected to the reaction tank and via one of the liquid receiving sections, and as a result, the liquids received in the reaction tank are stirred by the inflow of the outside air.
PCT/JP2008/072638 2007-12-14 2008-12-12 Fluid receiving cartridge and utilization of the same WO2009078352A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/747,597 US20100276309A1 (en) 2007-12-14 2008-12-12 Fluid containing cartridge and utilization of the same
CN2008801208048A CN101896598A (en) 2007-12-14 2008-12-12 Fluid receiving cartridge and utilization of the same
EP08862757A EP2241613A4 (en) 2007-12-14 2008-12-12 Fluid receiving cartridge and utilization of the same

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP2007323915 2007-12-14
JP2007-323914 2007-12-14
JP2007323914 2007-12-14
JP2007-323915 2007-12-14
JP2008061051 2008-03-11
JP2008-061051 2008-03-11
JP2008172659A JP2009240296A (en) 2007-12-14 2008-07-01 Fluid receiving cartridge and utilization of the same
JP2008-172659 2008-07-01

Publications (1)

Publication Number Publication Date
WO2009078352A1 true WO2009078352A1 (en) 2009-06-25

Family

ID=40795468

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/072638 WO2009078352A1 (en) 2007-12-14 2008-12-12 Fluid receiving cartridge and utilization of the same

Country Status (5)

Country Link
US (1) US20100276309A1 (en)
EP (1) EP2241613A4 (en)
JP (1) JP2009240296A (en)
CN (1) CN101896598A (en)
WO (1) WO2009078352A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108642141A (en) * 2018-06-07 2018-10-12 国家纳米科学中心 Nucleic acid detection reagent mixing adding set
CN108823088A (en) * 2018-06-07 2018-11-16 国家纳米科学中心 Nucleic acid detection apparatus based on micro-fluidic chip

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009171933A (en) * 2008-01-28 2009-08-06 Seiko Epson Corp Chip for biological specimen reaction, and method for biological specimen reaction
US20150298127A1 (en) * 2012-11-27 2015-10-22 Nec Corporation Fluidic chip and waste liquid processing method for same
CN105289385A (en) * 2015-10-22 2016-02-03 上海交通大学 Distorted arc-shaped micro mixer based on enhanced secondary flow effect
US11305291B2 (en) * 2016-02-18 2022-04-19 Siemens Healthcare Diagnostics Inc. Rack for a filtration device
CN110614125B (en) * 2018-06-28 2021-03-19 北京中科生仪科技有限公司 Micro-fluidic chip for whole blood nucleic acid detection
CN110616143B (en) * 2018-06-28 2022-05-27 北京中科生仪科技有限公司 Micro-fluidic chip for rapid detection of nucleic acid and application method thereof

Citations (7)

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Publication number Priority date Publication date Assignee Title
WO1993020441A1 (en) * 1992-03-27 1993-10-14 Abbott Laboratories Automated continuous and random access analytical system and components thereof
JP2004504828A (en) * 2000-07-28 2004-02-19 ジェネシステム Apparatus for heat-dependent linkage amplification of target nucleic acid sequences
WO2005064339A1 (en) * 2003-12-26 2005-07-14 Matsushita Electric Industrial Co., Ltd. Biological sample discriminating device, biological sample discriminating method, and biological sample discriminating plate
WO2005093388A1 (en) * 2004-03-26 2005-10-06 Infectio Recherche Inc. Removable microfluidic flow cell
JP2005313065A (en) 2004-04-28 2005-11-10 Yokogawa Electric Corp Cartridge for chemical reaction, manufacturing method therefor, and mechanism for driving cartridge for chemical reaction
JP2006308428A (en) * 2005-04-28 2006-11-09 Hitachi High-Technologies Corp Nucleic acid analysis method, nucleic acid analyzer, and cartridge for nucleic acid analysis
WO2006136990A2 (en) * 2005-06-23 2006-12-28 Koninklijke Philips Electronics N.V. Cartridge, system and method for automated medical diagnostics

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US5731212A (en) * 1994-12-20 1998-03-24 International Technidyne Corporation Test apparatus and method for testing cuvette accommodated samples
US20010055812A1 (en) * 1995-12-05 2001-12-27 Alec Mian Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
IT1299176B1 (en) * 1998-05-18 2000-02-29 Ams S R L MULTIPURPOSE TEST PLATE FOR ANALYSIS, PARTICULARLY FOR THE DIRECT ANALYSIS OF WHOLE BLOOD OR FLUIDS CONTAINING PARTICLES OR
JP4495866B2 (en) * 1999-05-28 2010-07-07 セフィード Cartridge for controlling chemical reactions
WO2003023410A1 (en) * 2001-09-07 2003-03-20 Innovadyne Technologies, Inc. Secondary liquid dispensing module for liquid handling system
DE10228917A1 (en) * 2002-06-24 2004-01-22 Epigenomics Ag Device for handling liquids in a plurality of channels
AU2003261360A1 (en) * 2002-08-02 2004-02-23 Amersham Biosciences (Sv) Corp Integrated microchip design
US7390464B2 (en) * 2003-06-19 2008-06-24 Burstein Technologies, Inc. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US8961900B2 (en) * 2004-04-28 2015-02-24 Yokogawa Electric Corporation Chemical reaction cartridge, method of producing chemical reaction cartridge, and mechanism for driving chemical reaction cartridge

Patent Citations (7)

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Publication number Priority date Publication date Assignee Title
WO1993020441A1 (en) * 1992-03-27 1993-10-14 Abbott Laboratories Automated continuous and random access analytical system and components thereof
JP2004504828A (en) * 2000-07-28 2004-02-19 ジェネシステム Apparatus for heat-dependent linkage amplification of target nucleic acid sequences
WO2005064339A1 (en) * 2003-12-26 2005-07-14 Matsushita Electric Industrial Co., Ltd. Biological sample discriminating device, biological sample discriminating method, and biological sample discriminating plate
WO2005093388A1 (en) * 2004-03-26 2005-10-06 Infectio Recherche Inc. Removable microfluidic flow cell
JP2005313065A (en) 2004-04-28 2005-11-10 Yokogawa Electric Corp Cartridge for chemical reaction, manufacturing method therefor, and mechanism for driving cartridge for chemical reaction
JP2006308428A (en) * 2005-04-28 2006-11-09 Hitachi High-Technologies Corp Nucleic acid analysis method, nucleic acid analyzer, and cartridge for nucleic acid analysis
WO2006136990A2 (en) * 2005-06-23 2006-12-28 Koninklijke Philips Electronics N.V. Cartridge, system and method for automated medical diagnostics

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Title
See also references of EP2241613A4

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108642141A (en) * 2018-06-07 2018-10-12 国家纳米科学中心 Nucleic acid detection reagent mixing adding set
CN108823088A (en) * 2018-06-07 2018-11-16 国家纳米科学中心 Nucleic acid detection apparatus based on micro-fluidic chip
CN108642141B (en) * 2018-06-07 2021-09-10 国家纳米科学中心 Nucleic acid detection reagent mixing and adding device
CN108823088B (en) * 2018-06-07 2021-10-01 国家纳米科学中心 Nucleic acid detection device based on micro-fluidic chip

Also Published As

Publication number Publication date
JP2009240296A (en) 2009-10-22
EP2241613A1 (en) 2010-10-20
EP2241613A4 (en) 2011-09-21
CN101896598A (en) 2010-11-24
US20100276309A1 (en) 2010-11-04

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