WO2009066562A1 - Promoteur de différenciation et/ou promoteur de prolifération pour des cellules souches d'érythrocytes, utilisation de la méthionine pour la prévention ou le traitement d'une anémie sénile, et compositions contenant de la méthionine - Google Patents
Promoteur de différenciation et/ou promoteur de prolifération pour des cellules souches d'érythrocytes, utilisation de la méthionine pour la prévention ou le traitement d'une anémie sénile, et compositions contenant de la méthionine Download PDFInfo
- Publication number
- WO2009066562A1 WO2009066562A1 PCT/JP2008/070042 JP2008070042W WO2009066562A1 WO 2009066562 A1 WO2009066562 A1 WO 2009066562A1 JP 2008070042 W JP2008070042 W JP 2008070042W WO 2009066562 A1 WO2009066562 A1 WO 2009066562A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methionine
- anemia
- thr
- preventing
- promoter
- Prior art date
Links
- 208000007502 anemia Diseases 0.000 title abstract 7
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 title abstract 4
- 229930182817 methionine Natural products 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000004069 differentiation Effects 0.000 title 1
- 210000003743 erythrocyte Anatomy 0.000 title 1
- 230000035755 proliferation Effects 0.000 title 1
- 210000000130 stem cell Anatomy 0.000 title 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 3
- 230000032683 aging Effects 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 206010065553 Bone marrow failure Diseases 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000003712 anti-aging effect Effects 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 230000032677 cell aging Effects 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN200880117597A CN101868230A (zh) | 2007-11-20 | 2008-11-04 | 干红细胞的分化促进剂和/或增殖促进剂以及用于预防或治疗老年性贫血的蛋氨酸应用和含有蛋氨酸的组合物 |
JP2009542517A JPWO2009066562A1 (ja) | 2007-11-20 | 2008-11-04 | 赤血球系幹細胞の分化促進剤及び/又は増殖促進剤、並びに老人性貧血を防止又は治療するためのメチオニンの使用及びメチオニンを含む組成物 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-300814 | 2007-11-20 | ||
JP2007300814 | 2007-11-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009066562A1 true WO2009066562A1 (fr) | 2009-05-28 |
Family
ID=40667387
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/070042 WO2009066562A1 (fr) | 2007-11-20 | 2008-11-04 | Promoteur de différenciation et/ou promoteur de prolifération pour des cellules souches d'érythrocytes, utilisation de la méthionine pour la prévention ou le traitement d'une anémie sénile, et compositions contenant de la méthionine |
Country Status (4)
Country | Link |
---|---|
JP (1) | JPWO2009066562A1 (fr) |
KR (1) | KR20100098400A (fr) |
CN (1) | CN101868230A (fr) |
WO (1) | WO2009066562A1 (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012147901A1 (fr) * | 2011-04-28 | 2012-11-01 | 味の素株式会社 | Composition pour atténuer les effets secondaires d'un médicament anticancer |
JP2018050551A (ja) * | 2016-09-29 | 2018-04-05 | 日本メナード化粧品株式会社 | 造血幹細胞の分化促進剤 |
WO2022250040A1 (fr) * | 2021-05-25 | 2022-12-01 | 味の素株式会社 | Composition pour l'amélioration ou la prévention de l'anémie ferriprive |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001510145A (ja) * | 1997-07-14 | 2001-07-31 | エヌ・ヴイ・ヌートリシア | メチオニンを含有する栄養組成物 |
JP2003155234A (ja) * | 2001-11-20 | 2003-05-27 | Fancl Corp | 抗老化組成物 |
JP2004519241A (ja) * | 2001-03-09 | 2004-07-02 | ソシエテ デ プロデユイ ネツスル ソシエテ アノニム | 高齢化に伴う生理的障害を改善し寿命を延ばす組成物 |
JP2005198642A (ja) * | 2003-12-15 | 2005-07-28 | Yutaka Miyauchi | 柑橘類の果皮を原材料とする液状飲用物 |
WO2007029730A1 (fr) * | 2005-09-06 | 2007-03-15 | Meiji Dairies Corporation | Composition d'acides amines utilisee dans la prevention ou le traitement de l'anemie chez le sujet age |
-
2008
- 2008-11-04 WO PCT/JP2008/070042 patent/WO2009066562A1/fr active Application Filing
- 2008-11-04 KR KR1020107013462A patent/KR20100098400A/ko not_active Application Discontinuation
- 2008-11-04 CN CN200880117597A patent/CN101868230A/zh active Pending
- 2008-11-04 JP JP2009542517A patent/JPWO2009066562A1/ja active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001510145A (ja) * | 1997-07-14 | 2001-07-31 | エヌ・ヴイ・ヌートリシア | メチオニンを含有する栄養組成物 |
JP2004519241A (ja) * | 2001-03-09 | 2004-07-02 | ソシエテ デ プロデユイ ネツスル ソシエテ アノニム | 高齢化に伴う生理的障害を改善し寿命を延ばす組成物 |
JP2003155234A (ja) * | 2001-11-20 | 2003-05-27 | Fancl Corp | 抗老化組成物 |
JP2005198642A (ja) * | 2003-12-15 | 2005-07-28 | Yutaka Miyauchi | 柑橘類の果皮を原材料とする液状飲用物 |
WO2007029730A1 (fr) * | 2005-09-06 | 2007-03-15 | Meiji Dairies Corporation | Composition d'acides amines utilisee dans la prevention ou le traitement de l'anemie chez le sujet age |
Non-Patent Citations (2)
Title |
---|
KARASAWA, M. ET AL.: "Methionine Partially Corrects the Impaired Deoxyribonucleic Acid Synthesis of B12-deficient Megaloblastic BBone Marrow Cells at Low Concentration", JAP. J. MED., vol. 25, no. 2, 1986, pages 155 - 161 * |
MASSOBRIO, V. et al, The antianemic action of methionine, Chemical Abstracts, 1952, Vol.47, 3976 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012147901A1 (fr) * | 2011-04-28 | 2012-11-01 | 味の素株式会社 | Composition pour atténuer les effets secondaires d'un médicament anticancer |
JP2018050551A (ja) * | 2016-09-29 | 2018-04-05 | 日本メナード化粧品株式会社 | 造血幹細胞の分化促進剤 |
WO2022250040A1 (fr) * | 2021-05-25 | 2022-12-01 | 味の素株式会社 | Composition pour l'amélioration ou la prévention de l'anémie ferriprive |
Also Published As
Publication number | Publication date |
---|---|
KR20100098400A (ko) | 2010-09-06 |
JPWO2009066562A1 (ja) | 2011-04-07 |
CN101868230A (zh) | 2010-10-20 |
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