WO2009063901A1 - クオラムセンシング阻害剤 - Google Patents
クオラムセンシング阻害剤 Download PDFInfo
- Publication number
- WO2009063901A1 WO2009063901A1 PCT/JP2008/070583 JP2008070583W WO2009063901A1 WO 2009063901 A1 WO2009063901 A1 WO 2009063901A1 JP 2008070583 W JP2008070583 W JP 2008070583W WO 2009063901 A1 WO2009063901 A1 WO 2009063901A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- quorum sensing
- sensing inhibitor
- hydrogen atom
- controlling agent
- alkyl group
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agronomy & Crop Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
本発明は、細菌性病害に対して極めて有効な防除剤を提供する。本発明のクオラムセンシング阻害剤及び農園芸用細菌性病害防除剤は、一般式(1)
[式中、R1はC1-5アルキル基又はフェニル基を示し、R2は水素原子又はC1-5アルキル基を示す。但し、R2が水素原子を示す場合、R1はメチル基であってはならない。]
で表されるピリミジノン化合物を含有する。
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08849623A EP2215910A4 (en) | 2007-11-13 | 2008-11-12 | QUORUM-SENSING INHIBITORS |
JP2009541151A JP5649304B2 (ja) | 2007-11-13 | 2008-11-12 | クオラムセンシング阻害剤 |
US12/739,554 US8507674B2 (en) | 2007-11-13 | 2008-11-12 | Quorum sensing inhibitor |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-294817 | 2007-11-13 | ||
JP2007294817 | 2007-11-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009063901A1 true WO2009063901A1 (ja) | 2009-05-22 |
Family
ID=40638750
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/070583 WO2009063901A1 (ja) | 2007-11-13 | 2008-11-12 | クオラムセンシング阻害剤 |
Country Status (5)
Country | Link |
---|---|
US (1) | US8507674B2 (ja) |
EP (1) | EP2215910A4 (ja) |
JP (1) | JP5649304B2 (ja) |
TW (1) | TW200926986A (ja) |
WO (1) | WO2009063901A1 (ja) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109908017A (zh) * | 2013-12-19 | 2019-06-21 | 高露洁-棕榄公司 | 口腔护理组合物 |
CN108210355B (zh) * | 2013-12-19 | 2022-02-18 | 高露洁-棕榄公司 | 口腔护理组合物 |
US12053486B2 (en) | 2018-03-09 | 2024-08-06 | Therazure LLC | Compositions for the treatment of infections in feet |
US20220022454A1 (en) * | 2018-04-19 | 2022-01-27 | Lida Plant Research S.L. | Synergistic mixture of plant defense inductors |
US20220248672A1 (en) * | 2019-07-08 | 2022-08-11 | Boyce Thompson Institute For Plant Research, Inc. | Compositions and methods for modulating microbiomes |
CN116267925A (zh) * | 2023-03-03 | 2023-06-23 | 贵州大学 | 法尼醇作为农用杀菌剂在植物细菌性病害中的应用 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4836193A (ja) | 1971-09-17 | 1973-05-28 | ||
US4022897A (en) * | 1974-03-04 | 1977-05-10 | E. R. Squibb & Sons, Inc. | CNS active compounds |
JPS5448795A (en) | 1977-08-19 | 1979-04-17 | Chinoin Gyogyszer Es Vegyeszet | Pyrazolopyrimidine derivatives and their manufacture |
JP2006508929A (ja) * | 2002-10-04 | 2006-03-16 | プラナ バイオテクノロジー リミティッド | 神経に対し活性な化合物 |
JP2006512290A (ja) | 2002-08-15 | 2006-04-13 | ザ・リサーチ・ファウンデーション・オブ・ステイト・ユニバーシティ・オブ・ニューヨーク | 自己誘導物質類似物質、自己誘導物質アゴニストおよびアンタゴニストのコンビナトリアル・ライブラリー、ならびにその使用方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
YU40704B (en) | 1977-05-10 | 1986-04-30 | Chinoin Gyogyszer Es Vegyeszet | Process for obtaininga 5(6)-thiobenzamidazole derivatives |
US5753664A (en) * | 1995-03-16 | 1998-05-19 | Takeda Chemical Industries, Ltd. | Heterocyclic compounds, their production and use |
WO2002018342A2 (en) | 2000-08-31 | 2002-03-07 | The University Of Iowa Research Foundation | Novel autoinducer molecules and uses therefor |
JP4836193B2 (ja) | 2006-12-27 | 2011-12-14 | 株式会社リコー | 画像形成装置及び画像形成方法 |
-
2008
- 2008-11-12 US US12/739,554 patent/US8507674B2/en not_active Expired - Fee Related
- 2008-11-12 EP EP08849623A patent/EP2215910A4/en not_active Withdrawn
- 2008-11-12 JP JP2009541151A patent/JP5649304B2/ja not_active Expired - Fee Related
- 2008-11-12 WO PCT/JP2008/070583 patent/WO2009063901A1/ja active Application Filing
- 2008-11-13 TW TW097143860A patent/TW200926986A/zh unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4836193A (ja) | 1971-09-17 | 1973-05-28 | ||
US4022897A (en) * | 1974-03-04 | 1977-05-10 | E. R. Squibb & Sons, Inc. | CNS active compounds |
JPS5448795A (en) | 1977-08-19 | 1979-04-17 | Chinoin Gyogyszer Es Vegyeszet | Pyrazolopyrimidine derivatives and their manufacture |
JP2006512290A (ja) | 2002-08-15 | 2006-04-13 | ザ・リサーチ・ファウンデーション・オブ・ステイト・ユニバーシティ・オブ・ニューヨーク | 自己誘導物質類似物質、自己誘導物質アゴニストおよびアンタゴニストのコンビナトリアル・ライブラリー、ならびにその使用方法 |
JP2006508929A (ja) * | 2002-10-04 | 2006-03-16 | プラナ バイオテクノロジー リミティッド | 神経に対し活性な化合物 |
Non-Patent Citations (6)
Title |
---|
CHEMICAL ABSTRACTS, vol. 85, no. 15, 11 October 1976, Columbus, Ohio, US; abstract no. 108662M, MESZAROS, ZOLTAN ET AL.: "4-Oxo-4H-pyrido[1, 2-a] pyrimidines" page 465; XP008134198 * |
FERRARINI P.L. ET AL.: "Synthesis of some 4H- Pyrimidin-4-ones investigated as antimicrobial agents", IL FARMACO, vol. 50, no. 1, 1995, pages 69 - 72, XP009040334 * |
MICROBIOLOGY, vol. 143, 1997, pages 3703 - 3711 |
MOLECULAR MICROBIOLOGY, vol. 54, no. 4, pages 921 - 934 |
See also references of EP2215910A4 |
TERESA R. ET AL., APPLIED AND ENVIRONMENTAL MICROBIOLOGY, April 2001 (2001-04-01), pages 1865 - 1873 |
Also Published As
Publication number | Publication date |
---|---|
JP5649304B2 (ja) | 2015-01-07 |
EP2215910A1 (en) | 2010-08-11 |
JPWO2009063901A1 (ja) | 2011-03-31 |
US8507674B2 (en) | 2013-08-13 |
TW200926986A (en) | 2009-07-01 |
US20100256369A1 (en) | 2010-10-07 |
EP2215910A4 (en) | 2012-04-04 |
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