WO2009063681A1 - Plaque de bioréacteur et procédé de traitement par bio réaction - Google Patents

Plaque de bioréacteur et procédé de traitement par bio réaction Download PDF

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Publication number
WO2009063681A1
WO2009063681A1 PCT/JP2008/065841 JP2008065841W WO2009063681A1 WO 2009063681 A1 WO2009063681 A1 WO 2009063681A1 JP 2008065841 W JP2008065841 W JP 2008065841W WO 2009063681 A1 WO2009063681 A1 WO 2009063681A1
Authority
WO
WIPO (PCT)
Prior art keywords
sample container
reactor
channel
reactor plate
plate
Prior art date
Application number
PCT/JP2008/065841
Other languages
English (en)
Japanese (ja)
Inventor
Nobuhiro Hanafusa
Original Assignee
Shimadzu Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shimadzu Corporation filed Critical Shimadzu Corporation
Priority to JP2009541066A priority Critical patent/JP4900485B2/ja
Publication of WO2009063681A1 publication Critical patent/WO2009063681A1/fr

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

Le problème à résoudre dans le cadre de la présente invention consiste à empêcher l'invasion de matières étrangères dans une plaque de bioréacteur ou une pollution environnementale se trouvant à l'extérieur de la plaque de bioréacteur. À cet effet, l'invention concerne une plaque de bioréacteur qui comprend : un bioréacteur bloqué (5), des canaux (13, 15, 17) pour le bioréacteur reliés au bioréacteur (5), un récipient d'échantillons (35) comprenant un récipient bloqué qui est utilisé séparément du bioréacteur (5), une seringue (51) destinée à fournir un liquide, une vanne d'interruption (63) destinée à relier la seringue (51) au canal (13) du bioréacteur ou au canal (35a) du récipient d'échantillons et un canal saillant (35d) comportant une protubérance qui est reliée à l'extrémité dans le côté du récipient d'échantillons (35) du canal (35a) du récipient d'échantillons. Le récipient d'échantillons (35) possède un élément de pénétration qui peut pénétrer par le canal saillant (35d) à une position telle qu'il se trouve en contact avec le liquide en utilisant la plaque du bioréacteur. Lorsque l'extrémité avant du canal saillant (35d) est insérée dans le récipient d'échantillons (35) par l'intermédiaire de l'élément de pénétration, le récipient d'échantillons (35) est relié au canal (35a) du récipient d'échantillons.
PCT/JP2008/065841 2007-11-15 2008-09-03 Plaque de bioréacteur et procédé de traitement par bio réaction WO2009063681A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009541066A JP4900485B2 (ja) 2007-11-15 2008-09-03 反応容器プレート及び反応処理方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007297086 2007-11-15
JP2007-297086 2007-11-15

Publications (1)

Publication Number Publication Date
WO2009063681A1 true WO2009063681A1 (fr) 2009-05-22

Family

ID=40638535

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/065841 WO2009063681A1 (fr) 2007-11-15 2008-09-03 Plaque de bioréacteur et procédé de traitement par bio réaction

Country Status (2)

Country Link
JP (1) JP4900485B2 (fr)
WO (1) WO2009063681A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9044757B2 (en) 2011-03-15 2015-06-02 Carclo Technical Plastics Limited Capillary fluid flow control
JP2017513496A (ja) * 2014-04-24 2017-06-01 ジーンウィーブ バイオサイエンシズ，インコーポレイティド 細胞の検出のための試薬カートリッジ及び方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004325462A (ja) * 2004-08-09 2004-11-18 Hitachi Ltd 化学分析装置と化学分析システム
JP2005502031A (ja) * 2001-08-28 2005-01-20 ユィロス・アクチボラグ 保持するためのマイクロ流体マイクロキャビティおよび他のマイクロ流体構造体
JP2006017719A (ja) * 2004-06-30 2006-01-19 Lifescan Scotland Ltd 流れ経路中の流れの調整方法
JP2006234590A (ja) * 2005-02-25 2006-09-07 Shimadzu Corp 反応容器
JP2006308366A (ja) * 2005-04-27 2006-11-09 Hitachi High-Technologies Corp 化学分析装置及び化学分析カートリッジ

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005502031A (ja) * 2001-08-28 2005-01-20 ユィロス・アクチボラグ 保持するためのマイクロ流体マイクロキャビティおよび他のマイクロ流体構造体
JP2006017719A (ja) * 2004-06-30 2006-01-19 Lifescan Scotland Ltd 流れ経路中の流れの調整方法
JP2004325462A (ja) * 2004-08-09 2004-11-18 Hitachi Ltd 化学分析装置と化学分析システム
JP2006234590A (ja) * 2005-02-25 2006-09-07 Shimadzu Corp 反応容器
JP2006308366A (ja) * 2005-04-27 2006-11-09 Hitachi High-Technologies Corp 化学分析装置及び化学分析カートリッジ

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9044757B2 (en) 2011-03-15 2015-06-02 Carclo Technical Plastics Limited Capillary fluid flow control
US9352316B2 (en) 2011-03-15 2016-05-31 Carclo Technical Plastics Limited Capillary fluid flow control
JP2017513496A (ja) * 2014-04-24 2017-06-01 ジーンウィーブ バイオサイエンシズ，インコーポレイティド 細胞の検出のための試薬カートリッジ及び方法

Also Published As

Publication number Publication date
JPWO2009063681A1 (ja) 2011-03-31
JP4900485B2 (ja) 2012-03-21

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