WO2009060601A1 - Agent for treatment of malignant tumor - Google Patents

Agent for treatment of malignant tumor Download PDF

Info

Publication number
WO2009060601A1
WO2009060601A1 PCT/JP2008/003193 JP2008003193W WO2009060601A1 WO 2009060601 A1 WO2009060601 A1 WO 2009060601A1 JP 2008003193 W JP2008003193 W JP 2008003193W WO 2009060601 A1 WO2009060601 A1 WO 2009060601A1
Authority
WO
WIPO (PCT)
Prior art keywords
agent
treatment
malignant tumor
malignant tumors
disclosed
Prior art date
Application number
PCT/JP2008/003193
Other languages
French (fr)
Japanese (ja)
Inventor
Takashi Suzuki
Toshihiro Akihisa
Keiichi Tabata
Motohiko Ukiya
Original Assignee
Nihon University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon University filed Critical Nihon University
Publication of WO2009060601A1 publication Critical patent/WO2009060601A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Disclosed is a novel derivative having remarkable curative effects on malignant tumors, for which a natural triterpene compound serves as a lead compound. Specifically disclosed is an agent for treatment of malignant tumors, which contains a faradiol derivative represented by the general formula (1) below or a salt thereof. (In the formula, R1 and R2 may be the same or different and each represents a linear or branched chain alkylene group having 2-8 carbon atoms.)
PCT/JP2008/003193 2007-11-06 2008-11-05 Agent for treatment of malignant tumor WO2009060601A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007288387A JP2011020922A (en) 2007-11-06 2007-11-06 Agent for treatment of malignant tumor
JP2007-288387 2007-11-06

Publications (1)

Publication Number Publication Date
WO2009060601A1 true WO2009060601A1 (en) 2009-05-14

Family

ID=40625510

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/003193 WO2009060601A1 (en) 2007-11-06 2008-11-05 Agent for treatment of malignant tumor

Country Status (2)

Country Link
JP (1) JP2011020922A (en)
WO (1) WO2009060601A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003277268A (en) * 2002-03-20 2003-10-02 Univ Nihon Human tumor cell proliferation suppressing agent
CN1861627A (en) * 2006-05-12 2006-11-15 中国药科大学 23-Hydroxyl betulinic acid kind derivant and preparing process, preparation and use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003277268A (en) * 2002-03-20 2003-10-02 Univ Nihon Human tumor cell proliferation suppressing agent
CN1861627A (en) * 2006-05-12 2006-11-15 中国药科大学 23-Hydroxyl betulinic acid kind derivant and preparing process, preparation and use thereof

Also Published As

Publication number Publication date
JP2011020922A (en) 2011-02-03

Similar Documents

Publication Publication Date Title
TW200612958A (en) Substituted imidazole derivatives
NZ580226A (en) Dimer compounds as inhibitors of iap
MX2009006742A (en) Novel compounds.
TN2010000101A1 (en) Fungicidal 2-alkylthio-2-quinolinyloxy -acetamide derivatives
MX2007002398A (en) New pharmaceutical compositions for the treatment of cancer.
MX2009008798A (en) Iminipyridine derivatives and their uses as microbiocides.
WO2007038868A3 (en) Novel enediyne compound and uses thereof
MX2009009774A (en) Quinoline derivatives as fungicides.
WO2009046842A3 (en) Thiazol derivatives for treating cancer
MX2009000657A (en) Compositions and methods for the treatment of mucositis.
MX2010003368A (en) Imidazole derivatives.
WO2009010139A3 (en) Quinazolinamide derivatives
WO2009047298A3 (en) Dimers of harmol or of its derivatives and uses thereof
MY147188A (en) Substituted imidazole compounds as ksp inhibitors
UA96759C2 (en) 2-ARYLINDOLE DERIVATIVES AS mPGES-I INHIBITORS
MX2010008226A (en) Difluorobiphenylamide derivatives for the treatment of ocular hypertension.
WO2009015368A3 (en) Multikinase inhibitors for use in the treatment of cancer
HK1127476A1 (en) Pyrazolopyrimidine derivative
WO2009008345A1 (en) Metal complex compound, cancer therapeutic composition comprising the metal complex compound as active ingredient, and intermediate for production of the metal complex compound
EA200901180A1 (en) DERIVATIVES OF TETRAPHYDROCHINOLINE AND THEIR APPLICATION FOR THE TREATMENT OF MALIGNANT NORMAL FORMATION
TW200800993A (en) Organic compounds
UA96745C2 (en) PYRIDO-, PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
WO2005079471A3 (en) Cytotoxin compound and method of isolation
UA101831C2 (en) Combined use of cholestanol derivative for antitumor therapy
TNSN06233A1 (en) 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, methods for production and use thereof as medicaments

Legal Events

Date Code Title Description
DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08848437

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08848437

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: JP