WO2009060601A1 - Agent for treatment of malignant tumor - Google Patents

Agent for treatment of malignant tumor Download PDF

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Publication number
WO2009060601A1
WO2009060601A1 PCT/JP2008/003193 JP2008003193W WO2009060601A1 WO 2009060601 A1 WO2009060601 A1 WO 2009060601A1 JP 2008003193 W JP2008003193 W JP 2008003193W WO 2009060601 A1 WO2009060601 A1 WO 2009060601A1
Authority
WO
WIPO (PCT)
Prior art keywords
agent
treatment
malignant tumor
malignant tumors
disclosed
Prior art date
Application number
PCT/JP2008/003193
Other languages
French (fr)
Japanese (ja)
Inventor
Takashi Suzuki
Toshihiro Akihisa
Keiichi Tabata
Motohiko Ukiya
Original Assignee
Nihon University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon University filed Critical Nihon University
Publication of WO2009060601A1 publication Critical patent/WO2009060601A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Disclosed is a novel derivative having remarkable curative effects on malignant tumors, for which a natural triterpene compound serves as a lead compound. Specifically disclosed is an agent for treatment of malignant tumors, which contains a faradiol derivative represented by the general formula (1) below or a salt thereof. (In the formula, R1 and R2 may be the same or different and each represents a linear or branched chain alkylene group having 2-8 carbon atoms.)
PCT/JP2008/003193 2007-11-06 2008-11-05 Agent for treatment of malignant tumor WO2009060601A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007288387A JP2011020922A (en) 2007-11-06 2007-11-06 Agent for treatment of malignant tumor
JP2007-288387 2007-11-06

Publications (1)

Publication Number Publication Date
WO2009060601A1 true WO2009060601A1 (en) 2009-05-14

Family

ID=40625510

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/003193 WO2009060601A1 (en) 2007-11-06 2008-11-05 Agent for treatment of malignant tumor

Country Status (2)

Country Link
JP (1) JP2011020922A (en)
WO (1) WO2009060601A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003277268A (en) * 2002-03-20 2003-10-02 Univ Nihon Human tumor cell proliferation suppressing agent
CN1861627A (en) * 2006-05-12 2006-11-15 中国药科大学 23-Hydroxyl betulinic acid kind derivant and preparing process, preparation and use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003277268A (en) * 2002-03-20 2003-10-02 Univ Nihon Human tumor cell proliferation suppressing agent
CN1861627A (en) * 2006-05-12 2006-11-15 中国药科大学 23-Hydroxyl betulinic acid kind derivant and preparing process, preparation and use thereof

Also Published As

Publication number Publication date
JP2011020922A (en) 2011-02-03

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