WO2009054150A1 - テトラピロール誘導体およびその医薬用途 - Google Patents

テトラピロール誘導体およびその医薬用途 Download PDF

Info

Publication number
WO2009054150A1
WO2009054150A1 PCT/JP2008/003044 JP2008003044W WO2009054150A1 WO 2009054150 A1 WO2009054150 A1 WO 2009054150A1 JP 2008003044 W JP2008003044 W JP 2008003044W WO 2009054150 A1 WO2009054150 A1 WO 2009054150A1
Authority
WO
WIPO (PCT)
Prior art keywords
medical purposes
tetrapyrrole derivative
preventing
agent
diabetic neuropathy
Prior art date
Application number
PCT/JP2008/003044
Other languages
English (en)
French (fr)
Inventor
Toyoshi Inoguchi
Ryoichi Takayanagi
Masakazu Fujii
Original Assignee
Kyushu University, National University Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyushu University, National University Corporation filed Critical Kyushu University, National University Corporation
Publication of WO2009054150A1 publication Critical patent/WO2009054150A1/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

【課題】 降圧作用や高カリウム血症を生じさせない糖尿病性腎症抑制剤を提供すること。 【解決手段】 一般式（Ｉ）で表されるテトラピロール誘導体又はその薬学的に許容された塩又はそのエステルを有効成分とする糖尿病性腎症抑制剤。
PCT/JP2008/003044 2007-10-25 2008-10-27 テトラピロール誘導体およびその医薬用途 WO2009054150A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37007P 2007-10-25 2007-10-25
US61/000,370 2007-10-25

Publications (1)

Publication Number Publication Date
WO2009054150A1 true WO2009054150A1 (ja) 2009-04-30

Family

ID=40579258

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/003044 WO2009054150A1 (ja) 2007-10-25 2008-10-27 テトラピロール誘導体およびその医薬用途

Country Status (1)

Country Link
WO (1) WO2009054150A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014043647A1 (en) * 2012-09-14 2014-03-20 Utah State University Therapeutic compositions and associated methods
US8980616B2 (en) 2009-11-04 2015-03-17 Utah State University Recombinant non-animal cell for making biliverdin

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MASAKAZU FUJII: "Biliverdin no Tonyobyo Jinsho Kaizen Koka to sono Bunshi Kijo no Kento", TONYOBYO GAPPEISHO, vol. 21, no. SUPPL., 30 September 2007 (2007-09-30), pages 65 *
SHUJI SASAKI: "Taishitsusei Odan Gunn Rat ni Okeru Tonyobyo Jinsho Yokusei Koka to sono Kijo no Kento", TONYOBYO GAPPEISHO, vol. 21, no. SUPPL., 30 September 2007 (2007-09-30), pages 65 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8980616B2 (en) 2009-11-04 2015-03-17 Utah State University Recombinant non-animal cell for making biliverdin
US9657321B2 (en) 2009-11-04 2017-05-23 Utah State University Recombinant non-animal cell for making biliverdin
WO2014043647A1 (en) * 2012-09-14 2014-03-20 Utah State University Therapeutic compositions and associated methods
US9119842B2 (en) 2012-09-14 2015-09-01 Utah State University Therapeutic meso-biliverdin IXα compositions and associated methods

Similar Documents

Publication Publication Date Title
WO2009054479A1 (ja) スピロ環化合物及びその医薬用途
WO2007117465A3 (en) Indazole compounds
WO2008010921A3 (en) Modulators of pharmacokinetic properties of therapeutics
WO2010136474A3 (en) Substituted aminobutyric derivatives as neprilysin inhibitors
WO2010122980A8 (ja) 新規甲状腺ホルモンβ受容体作動薬
WO2009017837A3 (en) Sublingual fentanyl spray
TW200728307A (en) Novel spirochromanone derivatives
TNSN08407A1 (en) Organic compounds
WO2012019430A8 (zh) 酞嗪酮类衍生物、其制备方法及其在医药上的应用
WO2008120725A1 (ja) 新規ピロリノン誘導体およびそれを含有する医薬組成物
WO2011012816A3 (fr) Formulation pharmaceutique
WO2007121921A3 (en) Purine derivatives for use as adenosin a2a receptor agonists
WO2008123207A1 (ja) オルニチン誘導体
WO2009041663A1 (ja) 皮膚疾患の予防及び／または治療剤
WO2008008660A3 (en) Cyclopentane derivatives as antiglaucoma agents
EP2196206B8 (en) Remedy for relieving skin troubles comprising morphinan derivative or pharmacologically acceptable acid addition salt thereof as the active ingredient
WO2010128050A3 (en) Dihydroorotate - dehydrogenasee inhibitors as virostatic compounds
MX2009003081A (es) Derivados de pirrola utiles para el tratamiento de enfermedades mediadas por citoquinas.
WO2008008718A3 (en) Cyclopentane derivatives as antiglaucoma agents
WO2009038412A3 (en) Beta-secretase inhibiting compounds
WO2008008700A3 (en) Substituted cyclopentane derivatives as therapeutic agents
WO2009055289A3 (en) Therapeutic substituted lactams
WO2008021804A3 (en) Therapeutic amides and related compounds
WO2007112913A3 (en) Benzimidazole derivatives
WO2009003719A3 (en) Indane-amine derivatives, their preparation and use as medicaments

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08840876

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08840876

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: JP