WO2009053920A1 - Contrôle du degré d'hydratation du corps humain - Google Patents
Contrôle du degré d'hydratation du corps humain Download PDFInfo
- Publication number
- WO2009053920A1 WO2009053920A1 PCT/IB2008/054371 IB2008054371W WO2009053920A1 WO 2009053920 A1 WO2009053920 A1 WO 2009053920A1 IB 2008054371 W IB2008054371 W IB 2008054371W WO 2009053920 A1 WO2009053920 A1 WO 2009053920A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- blood
- light
- blood vessel
- occlusion
- measuring
- Prior art date
Links
- 238000012544 monitoring process Methods 0.000 title claims abstract description 30
- 230000036571 hydration Effects 0.000 title claims abstract description 28
- 238000006703 hydration reaction Methods 0.000 title claims abstract description 28
- 210000004204 blood vessel Anatomy 0.000 claims abstract description 112
- 210000000601 blood cell Anatomy 0.000 claims abstract description 55
- 210000004369 blood Anatomy 0.000 claims abstract description 49
- 239000008280 blood Substances 0.000 claims abstract description 49
- 238000000034 method Methods 0.000 claims abstract description 40
- 238000003384 imaging method Methods 0.000 claims description 16
- 230000001678 irradiating effect Effects 0.000 claims description 14
- 238000001514 detection method Methods 0.000 claims description 11
- 238000010521 absorption reaction Methods 0.000 claims description 8
- 230000008859 change Effects 0.000 claims description 4
- 230000002123 temporal effect Effects 0.000 claims description 4
- 210000003462 vein Anatomy 0.000 abstract description 41
- 208000005156 Dehydration Diseases 0.000 description 17
- 230000018044 dehydration Effects 0.000 description 17
- 238000006297 dehydration reaction Methods 0.000 description 17
- 230000017531 blood circulation Effects 0.000 description 10
- 210000004905 finger nail Anatomy 0.000 description 8
- 238000005259 measurement Methods 0.000 description 6
- 230000010287 polarization Effects 0.000 description 6
- 238000002834 transmittance Methods 0.000 description 6
- 238000000386 microscopy Methods 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 230000000007 visual effect Effects 0.000 description 4
- INGWEZCOABYORO-UHFFFAOYSA-N 2-(furan-2-yl)-7-methyl-1h-1,8-naphthyridin-4-one Chemical compound N=1C2=NC(C)=CC=C2C(O)=CC=1C1=CC=CO1 INGWEZCOABYORO-UHFFFAOYSA-N 0.000 description 2
- 108010064719 Oxyhemoglobins Proteins 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 108010002255 deoxyhemoglobin Proteins 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 238000009533 lab test Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000036626 alertness Effects 0.000 description 1
- -1 and in particular Proteins 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000009530 blood pressure measurement Methods 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000000476 body water Anatomy 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000000701 chemical imaging Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000008571 general function Effects 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000006461 physiological response Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001902 propagating effect Effects 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 230000036555 skin type Effects 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/0261—Measuring blood flow using optical means, e.g. infrared light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4869—Determining body composition
- A61B5/4875—Hydration status, fluid retention of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
- A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Physiology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
L'invention concerne le domaine du contrôle du degré d'hydratation du corps humain basé sur la mesure du temps nécessaire au sang pour remplir à nouveau un vaisseau sanguin occlus, notamment en mesurant le temps de remplissage veineux (TRV) et/ou le temps de remplissage capillaire (TRC). L'invention propose un procédé I dans lequel le tissu comprenant le vaisseau sanguin est exposé à un rayonnement lumineux à polarisation linéaire à au moins une longueur d'onde prédéfinie ; la partie de la lumière réfléchie qui est polarisée perpendiculairement au rayonnement lumineux appliqué est recueillie sous la forme d'une image ; le vaisseau sanguin est occlus afin d'empêcher le sang d'y circuler ; l'occlusion du vaisseau sanguin est supprimée afin de permettre au sang de remplir à nouveau le vaisseau sanguin ; l'image est analysée afin de déterminer l'écoulement des cellules sanguines ; et le temps nécessaire pour revenir à un débit prédéfini des cellules sanguines après la suppression de l'occlusion est mesuré. Ce procédé permet de contrôler aisément, de manière spécifique et précise, le degré d'hydratation du corps humain.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN200710167897.7 | 2007-10-25 | ||
CN200710167897 | 2007-10-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009053920A1 true WO2009053920A1 (fr) | 2009-04-30 |
Family
ID=40332870
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2008/054371 WO2009053920A1 (fr) | 2007-10-25 | 2008-10-23 | Contrôle du degré d'hydratation du corps humain |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2009053920A1 (fr) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011078882A1 (fr) * | 2009-12-24 | 2011-06-30 | Children's Medical Center Corporation | Appareil et procédé de diagnostic à base de temps de remplissage capillaire |
CN104346604A (zh) * | 2013-07-26 | 2015-02-11 | 株式会社日立制作所 | 血管图像获取装置以及终端 |
WO2015155526A1 (fr) * | 2014-04-08 | 2015-10-15 | The University Of Nottingham | Mesure de remplissage de capillaire |
EP3000388A1 (fr) * | 2014-09-29 | 2016-03-30 | Nihon Kohden Corporation | Capteur et système de mesure de signal biologique |
WO2016087556A1 (fr) | 2014-12-02 | 2016-06-09 | Jacquet-Lagreze Matthias | Dispositif, système et procédé d'évaluation de la microcirculation sanguine d'un tissu |
US20170209091A1 (en) * | 2016-01-22 | 2017-07-27 | Welch Allyn, Inc. | Estimating Hydration Using Capillary Refill Time |
JP2018108278A (ja) * | 2017-01-04 | 2018-07-12 | 京セラ株式会社 | 推定装置、推定システム、推定方法及び推定プログラム |
US10231667B2 (en) | 2014-10-31 | 2019-03-19 | Koninklijke Philips N.V. | Non-invasive dehydration monitoring |
RU2712047C2 (ru) * | 2014-12-15 | 2020-01-24 | Конинклейке Филипс Н.В. | Способ измерения времени наполнения капилляров |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0714628A1 (fr) * | 1994-11-30 | 1996-06-05 | TOA MEDICAL ELECTRONICS CO., Ltd. | Analyseur destiné à l'examen non-invasif du sang |
US5983120A (en) * | 1995-10-23 | 1999-11-09 | Cytometrics, Inc. | Method and apparatus for reflected imaging analysis |
US20040249290A1 (en) * | 1999-07-26 | 2004-12-09 | Cardiosense | Non-invasive method and apparatus to detect and monitor early medical shock, and related conditions |
WO2005063116A1 (fr) * | 2003-12-22 | 2005-07-14 | Koninklijke Philips Electronics N. V. | Appareil et procede permettant de realiser l'imagerie spectrale polarisee orthogonale (opsi) |
US20050187478A1 (en) * | 2001-07-16 | 2005-08-25 | Art, Advanced Research Technologies Inc. | Multi-wavelength imaging of highly turbid media |
WO2007086071A2 (fr) * | 2006-01-30 | 2007-08-02 | Cardiosense Ltd. | Appareil, systeme et procede de determination d’etat cardio-respiratoire |
-
2008
- 2008-10-23 WO PCT/IB2008/054371 patent/WO2009053920A1/fr active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0714628A1 (fr) * | 1994-11-30 | 1996-06-05 | TOA MEDICAL ELECTRONICS CO., Ltd. | Analyseur destiné à l'examen non-invasif du sang |
US5983120A (en) * | 1995-10-23 | 1999-11-09 | Cytometrics, Inc. | Method and apparatus for reflected imaging analysis |
US20040249290A1 (en) * | 1999-07-26 | 2004-12-09 | Cardiosense | Non-invasive method and apparatus to detect and monitor early medical shock, and related conditions |
US20050187478A1 (en) * | 2001-07-16 | 2005-08-25 | Art, Advanced Research Technologies Inc. | Multi-wavelength imaging of highly turbid media |
WO2005063116A1 (fr) * | 2003-12-22 | 2005-07-14 | Koninklijke Philips Electronics N. V. | Appareil et procede permettant de realiser l'imagerie spectrale polarisee orthogonale (opsi) |
WO2007086071A2 (fr) * | 2006-01-30 | 2007-08-02 | Cardiosense Ltd. | Appareil, systeme et procede de determination d’etat cardio-respiratoire |
Non-Patent Citations (1)
Title |
---|
SHAVIT ITAI ET AL.: "A Novel Imaging Technique to Measure Capillary-Refill Time: Improving Diagnostic Accuracy for Dehydration in Young Children with Gastroenteritis", PEDIATRICS, no. 118, 2006, pages 2402 - 2408, XP002514733 * |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130211216A9 (en) * | 2009-12-24 | 2013-08-15 | Childeren's Medical Center Corporation | Capillary refill time diagnostic apparatus and methods |
WO2011078882A1 (fr) * | 2009-12-24 | 2011-06-30 | Children's Medical Center Corporation | Appareil et procédé de diagnostic à base de temps de remplissage capillaire |
US9603559B2 (en) | 2009-12-24 | 2017-03-28 | Children's Medical Center Corporation | Capillary refill time diagnostic apparatus and methods |
CN104346604A (zh) * | 2013-07-26 | 2015-02-11 | 株式会社日立制作所 | 血管图像获取装置以及终端 |
EP2848196A1 (fr) * | 2013-07-26 | 2015-03-18 | Hitachi Ltd. | Appareil pour la photographie des vaisseau sanguins |
WO2015155526A1 (fr) * | 2014-04-08 | 2015-10-15 | The University Of Nottingham | Mesure de remplissage de capillaire |
EP3000388A1 (fr) * | 2014-09-29 | 2016-03-30 | Nihon Kohden Corporation | Capteur et système de mesure de signal biologique |
US10231667B2 (en) | 2014-10-31 | 2019-03-19 | Koninklijke Philips N.V. | Non-invasive dehydration monitoring |
WO2016087556A1 (fr) | 2014-12-02 | 2016-06-09 | Jacquet-Lagreze Matthias | Dispositif, système et procédé d'évaluation de la microcirculation sanguine d'un tissu |
RU2712047C2 (ru) * | 2014-12-15 | 2020-01-24 | Конинклейке Филипс Н.В. | Способ измерения времени наполнения капилляров |
US11622690B2 (en) | 2014-12-15 | 2023-04-11 | Koninklijke Philips N.V. | Approach for measuring capillary refill time |
US20170209091A1 (en) * | 2016-01-22 | 2017-07-27 | Welch Allyn, Inc. | Estimating Hydration Using Capillary Refill Time |
US11344254B2 (en) * | 2016-01-22 | 2022-05-31 | Welch Allyn, Inc. | Estimating hydration using capillary refill time |
JP2018108278A (ja) * | 2017-01-04 | 2018-07-12 | 京セラ株式会社 | 推定装置、推定システム、推定方法及び推定プログラム |
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