WO2009041700A1 - Composition pharmaceutique - Google Patents

Composition pharmaceutique Download PDF

Info

Publication number
WO2009041700A1
WO2009041700A1 PCT/JP2008/067693 JP2008067693W WO2009041700A1 WO 2009041700 A1 WO2009041700 A1 WO 2009041700A1 JP 2008067693 W JP2008067693 W JP 2008067693W WO 2009041700 A1 WO2009041700 A1 WO 2009041700A1
Authority
WO
WIPO (PCT)
Prior art keywords
compound
stretch
pharmaceutical composition
composition
nerve
Prior art date
Application number
PCT/JP2008/067693
Other languages
English (en)
Japanese (ja)
Inventor
Manabu Nozaki
Shigeki Sawamura
Original Assignee
Kobayashi Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kobayashi Pharmaceutical Co., Ltd. filed Critical Kobayashi Pharmaceutical Co., Ltd.
Publication of WO2009041700A1 publication Critical patent/WO2009041700A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135Compounds containing heavy metals
    • A61K31/714Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention concerne une composition qui peut inhiber l'activité d'inhibition de l'étirement nerveux d'un composé 1 contenu dans cette composition ; et une composition capable de favoriser l'étirement nerveux, qui peut favoriser, de manière significative, l'étirement d'une cellule nerveuse. L'invention concerne ainsi une composition pharmaceutique caractérisée en ce qu'elle renferme un composé 1 et un composé 2 ; et une composition destinée à favoriser l'étirement nerveux, qui est caractérisée en ce qu'elle renferme au moins un composé 1 et un composé 2 et en ce qu'elle comprend en outre un composé 3.
PCT/JP2008/067693 2007-09-28 2008-09-29 Composition pharmaceutique WO2009041700A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-256016 2007-09-28
JP2007256016A JP5376785B2 (ja) 2007-09-28 2007-09-28 医薬組成物

Publications (1)

Publication Number Publication Date
WO2009041700A1 true WO2009041700A1 (fr) 2009-04-02

Family

ID=40511578

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/067693 WO2009041700A1 (fr) 2007-09-28 2008-09-29 Composition pharmaceutique

Country Status (2)

Country Link
JP (1) JP5376785B2 (fr)
WO (1) WO2009041700A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579584A (zh) * 2011-01-06 2012-07-18 赵能 一种疏通经络治理面瘫的保健丸

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5376786B2 (ja) * 2007-09-28 2013-12-25 小林製薬株式会社 神経細胞賦活組成物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001504104A (ja) * 1996-11-06 2001-03-27 ブリストル―マイヤーズ・スクイブ・カンパニー アルツハイマー病の治療法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000057879A1 (fr) * 1999-03-26 2000-10-05 Barry Reisberg Traitement des transformations intervenant dans le cerveau au moyen d'agents protegeant la myeline
JP5376786B2 (ja) * 2007-09-28 2013-12-25 小林製薬株式会社 神経細胞賦活組成物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001504104A (ja) * 1996-11-06 2001-03-27 ブリストル―マイヤーズ・スクイブ・カンパニー アルツハイマー病の治療法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SWEENEY, C.J. ET AL.: "Two drug interaction studies evaluating the pharmacokinetics and toxicity of pemetrexed when coadministered with aspirin or Ibuprofen in patients with advanced cancer", CLIN CANCER RES, vol. 12, no. 2, 2006, pages 536 - 542 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579584A (zh) * 2011-01-06 2012-07-18 赵能 一种疏通经络治理面瘫的保健丸

Also Published As

Publication number Publication date
JP2009084207A (ja) 2009-04-23
JP5376785B2 (ja) 2013-12-25

Similar Documents

Publication Publication Date Title
WO2008106128A3 (fr) Inhibiteurs d'urée et de carbamate de 11b-hydroxystéroïde déshydrogénase 1 cycliques
IL219234A (en) Pyrolidino Compounds [c – 4,3] Diprolidine Dual-Converted Positions n, n ', Pharmaceutical Preparations Containing and Uses
WO2008024497A3 (fr) INHIBITEURS DE LA 11β-HYDROXYSTÉROÏDE DÉSHYDROGÉNASE DE TYPE 1
WO2009075835A8 (fr) Inhibiteurs cycliques d'urée de la 11-hydroxystéroïde déhydrogénase 1
WO2010108074A3 (fr) Inhibiteurs de pi3 kinase
MX2010005889A (es) Derivados de tiofeno como agonistas de s1p1/edg1.
TN2012000152A1 (en) Spiropiperidine compounds and pharmaceutical use thereof for treating diabetes
TN2012000248A1 (en) Novel spiropiperidine compounds
WO2010003133A3 (fr) Modulateurs de cdk
WO2011014795A3 (fr) Composés et compositions pouvant servir d'inhibiteurs de la kinase syk
WO2008103470A3 (fr) Composés létaux dépendants du signal de ras oncogénique
SG179034A1 (en) 2 -aminodihydro [1, 3] thiazines as bace 2 inhibitors for the treatment of diabetes
HK1133596A1 (en) Inhibitors of diacylglycerol o-acyltransferase type 1 enzyme
WO2008032191A3 (fr) Composés spiro-oxazolidinone et leur utilisation comme potentialisateurs du récepteur métabotropique du glutamate
WO2008070268A3 (fr) Compositions pharmaceutiques
MX2013005069A (es) Formas cristalinas de sal de clorhidrato de (4a-r, 9a-s)-1-(1h-benzoimidazol-5-carbonil)-2,3,4,4a,9,9a,-hexahidro-1h -indeno[2,1-b]piridin-6-carbonitrilo y su uso como inhibidores de 11 beta-hidroxiesteroide deshidrogenasa 1.
WO2009038412A3 (fr) Composés inhibiteurs de la béta-sécrétase
MY165041A (en) Composition for improving brain function and method for improving brain function
WO2011088160A3 (fr) Nouveaux inhibiteurs de cyp17
WO2010123959A3 (fr) Antagonistes ccr3 d'arylsulfonamides 2,5-disubstitués
WO2009129208A8 (fr) Compositions et procédés permettant d'induire une réponse au stress du réticulum endoplasmique
WO2012075015A3 (fr) Compositions pharmaceutiques orales de métronidazole
WO2010072770A3 (fr) Analogues de griséofulvine pour le traitement du cancer par inhibition de l'agrégat centrosomial
TW200800993A (en) Organic compounds
WO2009041700A1 (fr) Composition pharmaceutique

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08834472

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08834472

Country of ref document: EP

Kind code of ref document: A1