WO2009016655A1 - Appareil d'aérosol - Google Patents

Appareil d'aérosol Download PDF

Info

Publication number
WO2009016655A1
WO2009016655A1 PCT/IT2007/000534 IT2007000534W WO2009016655A1 WO 2009016655 A1 WO2009016655 A1 WO 2009016655A1 IT 2007000534 W IT2007000534 W IT 2007000534W WO 2009016655 A1 WO2009016655 A1 WO 2009016655A1
Authority
WO
WIPO (PCT)
Prior art keywords
inhaler
filter
compressor unit
compressed air
inlet section
Prior art date
Application number
PCT/IT2007/000534
Other languages
English (en)
Inventor
Stefano Chiesa
Original Assignee
Ca.Mi. Di Attolini Mario E C. S.N.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ca.Mi. Di Attolini Mario E C. S.N.C. filed Critical Ca.Mi. Di Attolini Mario E C. S.N.C.
Priority to PCT/IT2007/000534 priority Critical patent/WO2009016655A1/fr
Publication of WO2009016655A1 publication Critical patent/WO2009016655A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A61M16/0063—Compressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/106—Filters in a path
    • A61M16/107—Filters in a path in the inspiratory path

Definitions

  • This invention relates to aerosol apparatus.
  • the invention relates in particular to an apparatus for nebulizing a medicinal substance, usually liquid.
  • nebulizing apparatus is widely used for aerosol therapy, that is to say, for treating disorders of the upper respiratory tract such as asthma or bronchial conditions.
  • a medicinal liquid 0 in the form of an aerosol that is to say, a dispersion or fine spray of particles of the medicinal liquid is administered by inhalation.
  • Aerosol apparatuses;- are widely used especially in paediatric therapy and to treat chronic disorders of the respiratory system and come in many different fqrms and sizes to meet different user requirements. 5
  • Known mainly, for domestic, use are.
  • pneumatic nebulizing apparatuses so called ( , ⁇ beca ⁇ e ⁇ ,they,comprise, ; a.compressor unit that sucks air in ; , from. the environment arid, pumps it to a nebulizing inhaler containing the medicinal
  • the nebulizing inhaler has an inlet, section connected to 0 the .compressor, .unit for receiving airland an outlet section for, releasing the nebulizing inhaler
  • Nebulization occurs inside . the, inhaler. by the action of the> compressed an; .according to a welkknqwn.technique.
  • Tpday i aerosol j therapy ⁇ s, used mainly to ⁇ administer,, specific, medicines.
  • for tjie treatment of ( diseases of. all parts, of the .respiratory.. system, fromjthe part 5 Jmow ⁇ as , ⁇ e, "upper, ; respiratory. tract” (nose, mouth, throat) to the part known, instead, as the “lower respiratory tract” (pulmonary alveoli).
  • system means, in the case of compressed air apparatus, the assembly composed of the mechanical part, that is to say, the compressor unit that produces the flow of compressed air, and the nebulizing part, that " is to say, the inhaler, that reduces the prescribed drug into , a fine spray or nebulized mist to be inhaled by the patient.
  • AU aerosol apparatuses available on the market today have an air filtration system located at the inlet section of the compressor unit.
  • the filter Rather than providing a protective barrier for the user, the filter ensures the correct operation of the compressor.
  • the air, that cornes.iintp contact, with .the compressor, (downstream, of. ; the filter and hence, directed .towards the inhaler, and .the patient) constitutes, a medium by which extrane,pus parti ⁇ les, and from, different. parts of the compressed air circuit insideithe ⁇ apparatus (for example, , the .compressor pump ? . the pipes, inside the compressor.pr; the : hose that carries, the air, from the compressor, to the; inhaler) can ..easily , be transmitted.
  • the compressed air circuit insideithe ⁇ apparatus for example, , the .compressor pump ? . the pipes, inside the compressor.pr; the : hose that carries, the air, from the compressor, to the; inhaler
  • FIG. 15 7 ; - Figure 3- illustrates .a. third embodiment of the apparatus, of . Figure,!,;,, ,, , ;s
  • The,.apparatus 1 comprises a nebulizing inhaler 2 connected to a compressor 5 unit :;3( V
  • the compressor unit ; 3 constitutes. a source of compressed air. , ; .
  • the inhaler 2 has an inlet section 4 and an outlet section 5.
  • the inhaler 2 receives compressed air from the compressor unit 3 through the inlet section 4.
  • the compressed air is used to nebulize a medicinal product located inside the inhaler 2.
  • the medicinal product may be a liquid originally contained inside an ampoule and poured into the inhaler 2 when required.
  • the nebulized medicinal product is released to the outside environment through the outlet section 5 of the inhaler 2.
  • the inhaler 2 is connected to the compressor unit 3 by a compressed air inlet pipe 6.
  • the pipe 6 has a first end 7 connected to the inhaler 2 inlet section 4, and a second end 8 connected to an outlet section 9 of the compressor unit 3; said outlet section 9 of the compressor unit 3 consisting substantially of the delivery section of a pump forming part of the compressor , unit 3. ,, ,., . .. , ,• • . , ⁇ ; •.. . ⁇ ••
  • the apparatus 1 comprises, a; filter 10 located betweenthe . .compressor unit 3, and ⁇ the; inhaler 2 for filtering the compressed air.flqwmgirpm Jhe compressor unit 3 to the mhaler.,More specifically, the filter ⁇ 0 is > advantageously .located between the outlet ,sectio ; ⁇ t .9. of. the compressor unit 3 : and.the inlet section 4 of the inhaler 2.
  • the filter ,1 Q is! designed tq- clean the air of any, impurities, and substances which, ifinhaled; by a patient, might be dangerous to that patient's, health. • • -. .
  • This invention has ; . three. embQdiments,, . depending. on the position .of. the filter 10 m. the apparatus 1. . ⁇ ⁇ , , . • . . , ., ., , .
  • the filter. 1.0 is located at the inlet section A. of the inhaler 2.
  • H,e ⁇ ce in this case, the filter 10 _is built into the inhaler 2, or coupled to the inhaler 2.
  • the filter 10 is located at the outlet section 9 of the compressor unit 3.
  • the filter 10 is built into the compressor unit 3, or coupled to the compressor unit 3.
  • the filter 10 is built into the inlet pipe 6, or coupled to the inlet pipe 6.
  • the filter 10 operates on the compressed air from the compressor unit 3 before the air comes into contact with the medicinal product inside the inhaler 2. This advantageously avoids the risk of the patient inhaling unwanted substances transported by the flow of compressed air without thereby reducing the efficacy of the aerosol treatment (as. wquld be the case if the filter operated on a fluid where the medicinal product is already present since the medicinal product would itself be filtered, out). . , ... . , . . ;.. , ,. ; . . ., ; ( , h ,., .
  • AIs. o depending oji ho ⁇ the filter 10 is mounted in the apparatus 1 (or how ⁇ e, filter the jnhajer 2,, to the inlet pipe , i6, or , to, the compressor unit 3,), -,thi ⁇ , invention has.three further embodiments. ⁇ e.detaHed .description; that, follows regards, in pariicular, the. different ways of coupling the • filter 10 to the. inhaler 2,. and. therefore /eiers to ,the first embodiment pfpih.e apparatus illustrated m Figure J, where tib.e. filter IQ is built into the inhaler 2'. M . , , .; ,. • , . ⁇ . .
  • the filter 10 comprises a mounting element 11 defining a passage 12.
  • the filter 10 also comprises a filtering membrane 13 located inside the mounting element 11 and designed to filter a flow of air moving through the passage 12.
  • the membrane is preferably of antibacterial type with high filtering characteristics capable of trapping not only dust but also specific bacterial flora according to filtering specifications declared and certified by the manufacturer.
  • the inhaler 2 is especially shaped to fit the mounting element llrofthe filterl Oi
  • the mounting element 11 is coupled to the inhaler 2 removably so that the filter ,10 pan be substituted when; necessary.
  • the, coupling is preferably, of the bayonet., type (see- example illustrated in Figure 4), although other types of coupling are imaginable. ,
  • the • mounting : eleme ⁇ 1; » 11. . is, coupled, to the inhaler ,2 irrerno.vably.
  • the mounting element 1.1. is -fixed to. the inhaler.2 preferably, by ultraspund. welding; or, using specific, high-strength adhesives capable. of irjcemovably. fixing. the materials of whjch.the parts to be fixed are made., to. each other.
  • the inlet ⁇ section 4 of the inhaler 2 defines a seat 14 in which the filtering membrane. ,13,; is fitted...
  • the seat- 1.4 -,and the .filtering membrane 13 define the filter 10, which is built into the inhaler 2.
  • the seat 14 might be defined by fixing a lid 15 to a body 16 of the inhaler 2 at the inlet section 4.
  • the lid 15 also defines the passage 12 for the compressed air flowing into the inhaler 2.
  • the lid 15 of the inhaler 2 is removably connected to the body 16 of the inhaler 2 at the inlet section 4.
  • the lid 15 is preferably screwed to the body.16 of the inhaler 2, although other fastening systems are imaginable, such as, for example, a straight pin and hole fastening system or a pin and hole system fastened by turning.
  • the filter 10 being comprised of the filter membrane 13 defined by the. Hd ;15 coupled, to, -the body.16,. of, the inhaler 2, inbuilt, into the inhaler 2 but, at the same time, can be substituted.
  • This invention also provides a nebulizing inhaler 2 for aerosol therapy advantageously provided with a filter that operates on the compressed air delivered by a compressor unit (or by any other source of compressed air) before the air comes into contact with the medicinal product.
  • the invention also provides a pipe 6 for connecting the aerosol nebulizing inhaler 2 to a source of compressed air (for example, the compressor unit 3) to enable the medicinal product in the inhaler 2 to be nebulized and fitted with the filter 10 for filtering the compressed air.
  • a source of compressed air for example, the compressor unit 3
  • a separate element comprising . , a. mounting, element .11 with a filtering membrane 13 fittqd.to, it.
  • a separate element comprising . , a. mounting, element .11 with a filtering membrane 13 fittqd.to, it.
  • might be remoyabb/ ,orHirremovably c,ouple.d to t trie , pipe, inuthe same way as described above in connection with the inhaler 2-.
  • Fur ⁇ ther, ; the filter . 10 might be . coupled to. the pipe 6 (or built into the pipe 6) at the, first, end 7 or, . alternatively,, at the second, end 8 pr, alternatively ⁇ in ,a part of the pipe ⁇ between the first end and the second.
  • This, invention also contemplates .the, provision of a j compressor unit 3 that can ,be, connected, in an aeros,pji apparatus, to a nebulizing inhaler 2 in order to supply. the latter with, a flow; of compressed air by which a medicinal product inside the inhaler 2 . can be , nebulized, the compresjsqr -unit 3 being advantageously equipped with a filter 10 for filtering the compressed air at an outlet section 9 of the compressor unit 3, that is to say, downstream of the delivery end of a pump of the compressor unit 3.
  • this 5 can be done in different ways according to three different embodiments, in the same way as described above.
  • the filter 10 may be built into the compressor unit 3 or, alternatively, it may be a separate element fixed to the compressor unit 3 irremovably or removably. Notice that, in addition to the filter 10,. the compressor unit 3 also comprises0 a system for cleaning the air intake (according to a known method).
  • the invention advantageously provides an aerosol apparatus that is particularly safe for. the /patient's health thanks to a. filter fpr cleaning, the cprnpressed , air, - flowing . into ; the, inhaler which, during aerosol therapy, prevents. the.patient from, inhaling unwanted substances that may be present5 in the flp w of compressed air;..
  • the Afferent, embodiments t contemplated, , the, invention can advantageously safeguard, tfie, patient's health, thanks to ., the. ) possibility , of applying disposable, single-use replaceable filters ithat.can be coupled to the nebulizing inhaler or to a.pipe 6 connecting the. inhalei; 2 to the compressor0 units , (where, such a. pipe, is, present), or to, the, .compres ⁇ sqr,.unit.3 itself, ,

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention porte sur un appareil d'aérosol (1) qui comprend une unité de compresseur (3), un inhalateur de nébulisation (2) ayant une section d'entrée (4) connectée de façon fonctionnelle à l'unité de compresseur (3) pour recevoir de l'air comprimé et une section de sortie (5) pour libérer un produit médicinal à l'environnement extérieur après qu'il a été nébulisé par l'air comprimé dans l'inhalateur (2), et un filtre (10) situé entre l'unité de compresseur (3) et la section d'entrée (4) de l'inhalateur (2) pour filtrer l'air comprimé. Des appareils d'aérosol de l'état antérieur de la technique n'ont pas de systèmes filtrants pour nettoyer l'air circulant hors du compresseur mais uniquement des filtres qui nettoient l'air circulant à l'intérieur du compresseur. Ceci veut dire qu'il existe un risque que le patient inhale des substances non souhaitées ou potentiellement nuisibles (telles que des particules ou de la poussière produite par usure des parties mobiles, du compresseur ou des corps externes, aspirées de l'extérieur et non retenues par le filtre d'entrée) transportées vers l'inhalateur par l'écoulement d'air comprimé, et provenant, par exemple, de l'intérieur de l'unité de compresseur elle-même.
PCT/IT2007/000534 2007-07-27 2007-07-27 Appareil d'aérosol WO2009016655A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/IT2007/000534 WO2009016655A1 (fr) 2007-07-27 2007-07-27 Appareil d'aérosol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IT2007/000534 WO2009016655A1 (fr) 2007-07-27 2007-07-27 Appareil d'aérosol

Publications (1)

Publication Number Publication Date
WO2009016655A1 true WO2009016655A1 (fr) 2009-02-05

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IT2007/000534 WO2009016655A1 (fr) 2007-07-27 2007-07-27 Appareil d'aérosol

Country Status (1)

Country Link
WO (1) WO2009016655A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9179691B2 (en) 2007-12-14 2015-11-10 Aerodesigns, Inc. Delivering aerosolizable food products
WO2017001486A1 (fr) * 2015-06-30 2017-01-05 Blue Safety Gmbh Unité d'alimentation en eau industrielle pour alimenter une unite de traitement médical, unité de traitement dentaire et procédé de fonctionnement
RU193395U1 (ru) * 2019-06-17 2019-10-28 Евгений Викторович Крейдин Генератор сухого солевого аэрозоля

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB704070A (en) * 1950-08-02 1954-02-17 Rybar Lab Ltd Improvements in or relating to atomisers
EP0771571A1 (fr) * 1995-10-31 1997-05-07 SANYO ELECTRIC Co., Ltd. Système atomiseur comprenant un dispositif d'apport de pression et des unitées pulvérisatrices
EP1468659A2 (fr) * 2003-04-14 2004-10-20 Piero Angelo Policicchio Prophylaxie dentaire et dispositif d'air

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB704070A (en) * 1950-08-02 1954-02-17 Rybar Lab Ltd Improvements in or relating to atomisers
EP0771571A1 (fr) * 1995-10-31 1997-05-07 SANYO ELECTRIC Co., Ltd. Système atomiseur comprenant un dispositif d'apport de pression et des unitées pulvérisatrices
EP1468659A2 (fr) * 2003-04-14 2004-10-20 Piero Angelo Policicchio Prophylaxie dentaire et dispositif d'air

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9179691B2 (en) 2007-12-14 2015-11-10 Aerodesigns, Inc. Delivering aerosolizable food products
WO2017001486A1 (fr) * 2015-06-30 2017-01-05 Blue Safety Gmbh Unité d'alimentation en eau industrielle pour alimenter une unite de traitement médical, unité de traitement dentaire et procédé de fonctionnement
CN107920878A (zh) * 2015-06-30 2018-04-17 蓝色安全有限公司 用于向医疗单元、牙科医疗单元供应的工艺用水供应单元及操作方法
AU2016286269B2 (en) * 2015-06-30 2020-10-01 Blue Safety Gmbh Process water supply unit for supplying a medical treatment unit, dental medical treatment unit and operating method
US10993780B2 (en) 2015-06-30 2021-05-04 Blue Safety Gmbh Process water supply unit for supplying a medical treatment unit, dental medical treatment unit and operating method
RU193395U1 (ru) * 2019-06-17 2019-10-28 Евгений Викторович Крейдин Генератор сухого солевого аэрозоля

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