WO2009009818A1 - Thérapie cellulaire bio-vivante - Google Patents

Thérapie cellulaire bio-vivante Download PDF

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Publication number
WO2009009818A1
WO2009009818A1 PCT/AU2008/000106 AU2008000106W WO2009009818A1 WO 2009009818 A1 WO2009009818 A1 WO 2009009818A1 AU 2008000106 W AU2008000106 W AU 2008000106W WO 2009009818 A1 WO2009009818 A1 WO 2009009818A1
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WO
WIPO (PCT)
Prior art keywords
skin
ovine
treatment
penetration
liquid
Prior art date
Application number
PCT/AU2008/000106
Other languages
English (en)
Inventor
Tanti Diana Tanujaya
Original Assignee
Tanti Diana Tanujaya
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanti Diana Tanujaya filed Critical Tanti Diana Tanujaya
Publication of WO2009009818A1 publication Critical patent/WO2009009818A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/982—Reproductive organs; Embryos, Eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/83—Electrophoresis; Electrodes; Electrolytic phenomena

Definitions

  • BIO-Living Cell Therapy is a skin treatment which treating skin problem by stimulating the skin to grow in purpose to replace and repair the damaged skin tissue.
  • Pure Ovine Amniotic liquid from the sheep embryo is used in this treatment as the serum which is penetrated to the skin tissues.
  • This ovine amniotic liquid contains the essential substance - i.e. nucleic acids (DNA and RNA), amino acids, vitamins, minerals and many others - needed by our body to repair or replace damaged skin cells.
  • Ionthophoresis system is a system which based on the properties of negative and positive ions (attraction and repulsion forces between ions). By combining ionthophoresis system and the natural body 'attraction and repulsion' properties, we can create a similar system as the normal skin system i.e.: Excretion
  • BIO-Living Cell Therapy is skin treatment which combines together ionthophoresis system and ovine amniotic liquid.
  • Ovine amniotic liquid from the sheep embryo has only 0.14 ppm (per part million) differences with human DNA.
  • Ionthophoresis system created a stimulation of skin characteristics of absorption which helps the penetration process of ovine amniotic liquid into the skin.
  • Ionizer machine is the machine used in this treatment which based on the ionthophoresis system. Every 10 level of the units in the machine is equal to 1 ml deep penetration to the skin and within 5 minutes after the penetration of ovine amniotic liquid, the 3 Growth Factor starts to occur.
  • FIG 1 is a diagram to illustrate the stages and system of BIO-LIVING Cell Therapy.
  • Pure ovine amniotic liquid (1) is penetrated into the skin tissue using the ionthophoresis system (2). This penetration will lead to 3 Growth Factors (3) simultaneously. The 3 Growth factors will then result in the repair, replacement and rebuild (4) the damaged and problematic area of the skin tissue.
  • the Roller is connected to the ionizer machine which produces ionthophoresis system and the pure sheep embryo is dropped simultaneously (figure 2).
  • Ionthophoresis system penetrates the pure sheep ovine amniotic liquid into the skin tissues.
  • the machine also produces micro vibrations which help the penetration (figure 3). After a few minute - as explained above - the "3 Growth Factor" occurred and repair, replace and rebuild new skin tissues over the damaged area (figure 4).
  • the 3 Growth Factor are:
  • the ovine liquid carries important substances which needed by the body, therefore the ovine liquid will rebuild the natural moisture to keep the elasticity and softness and also provide enough content of water and provide enough water content for skin.
  • the content of amino acids and vitamins in ovine liquid will caused the growth of immune system and therefore evoke the detoxification to occur.
  • the skin is sensitive or weak or has a deposit unused substance inside, for example melanoma and melasma, detoxification may occur.
  • itchiness, redness and red spots will occur on the problematic area.
  • the highest reaction occurs within about 48 hours and after that it will calm down in about 3-4 days time. At 5 th or 6 th day the skin will be dry; on the 7 th day growth of new skin can be seen.
  • Skin cancer is developing because the skin has been exposed for too long with the UV rays.
  • Our skin itself is the barrier from the UV rays but due to harsh environment some parts of our skin can be damaged and cause the 'barrier' disappears. This caused UV rays to penetrate deeper into the skin and caused the skin cancer.
  • Melanoma formed firstly under the epidermis layer of skin (figure 5), so it is really hard to be recognized but after a while it will develop and it can be seen as a brown spot on skin (figure 6) which then it will develop to a blackish/dark purplish lump (figure 7).
  • the small skin cancer can be removed (figure 8 and 9) without leaving obvious mark by the BIO-LIVING Cell Therapy.
  • the penetration of ovine liquid will strengthen our body immune and our healthy tissues will defeat the skin cancer.
  • the cancer will be removed by 'suction' from the ionizer (opposite mechanism of penetration).
  • the minimum mark will covered by penetrating the ovine liquid to rebuild new skin tissue over the mark.
  • the suction of skin cancer is by using the ionthophoresis system - but opposite mechanism of penetration — which produced a safer way of suction with less pain. If the melanoma is big, the suction may leave mark and further treatment (penetration of pure sheep ovine liquid) to cover the mark may be needed to rebuilt the new skin tissue.
  • This skin therapy has produce treatments that can cure and repair almost all skin problems back to the nearest individual's normal skin condition with light side effect and less pain.
  • This therapy is safe and do not involve injection, chemical abrasion and surgical operation system.
  • Figure 11 is showing that her skin is very sensitive before the treatment. But after a single treatment, her skin becomes much less sensitive and shinier. Replace the lose skin tissues because of a severe damaged in the skin tissues, hormonal, chemical and the surrounding environment. Scar, eye paunch, wrinkle, and blemish are example of the 'lose' skin condition. Below are some pictures for people who had the treatment:
  • Figure 16 is showing a case of wrinkle. Before the treatment there are deep lines around the eyes and lips and cheeks. After 5x treatments the lines became light and less obvious, the skin also became shinier. After 8x treatments the lines are gone and the skin became smooth.
  • Figure 17 is showing a freckles skin problem. The girl has freckles since she was a teenager. After 15x treatments, most of her freckles had lessened and her skin is not sensitive anymore.
  • Figure 18 is showing a case of face lifting.
  • Her age is about 75 years old. She has a saggy skin, eye pounce, weak skin (after sick) melasma, dark circle and some dark spot around her eyes. After 4x treatments, her skin became healthier, the dark circle and the dark spots removed. The fibroblast is grown at that time. After 6x treatments, the dark spots marks are removed without leaving obvious mark.
  • FIG. 19 Another case of face lifting is shown in figure 19.
  • Her age is 54 years old with problem of light burned skin (especially on the right cheek, eyes and chin), dark circle (around eyes) and some freckles under the eyes.
  • Figure 20 is showing before-and-after picture of a woman who has a sensitive skin, dark eyes ring and wrinkles. Her age is 67 years old. Firstly she has a very sensitive skin, dark eyes and wrinkle around eyes.
  • this treatment is strengthening the immune system, it can be used to cure the early stage or symptoms of skin cancer.
  • the pure sheep ovine liquid is penetrated to the skin will increase our immune system and also build a healthier skin tissue which strong enough to defeat the early skin cancer. After the skin cancer defeated, it then sucks out again using the ionthophoresis system (opposite to the penetration circulation of ions). The small mark of the suction will be easily cover by penetrating the ovine liquid to rebuilt new skin tissue on the small scar area.
  • Weaker skin barrier will allow most of the UV rays to penetrate the dermis and cause greater chance of the formation of melanoma. This treatment can build a stronger skin barrier which allows only little of UV rays to penetrate the inner layer of the skin.
  • Figure 1 illustrates the mechanism of BIO-LIVING CELL Therapy.
  • Figure 2 is an illustration of the first stage of BIO-LIVING CELL Therapy.
  • Figure 3 is an illustration of the middle stage of BIO-LIVING CELL Therapy.
  • Figure 4 is an illustration of ovine amniotic liquid which had been penetrated and the The pure sheep ovine liquid had penetrated to the skin tissues and become part of the skin tissues.
  • Figure 5 is a picture of the early stage of the formation of skin cancer.
  • Figure 6 is showing animated picture and the real appearance of the skin cancer under development.
  • Figure 7 is showing both animated picture and real appearance of skin cancer which already developed big enough to form a lump.
  • Figure 8 is pictures of the result of small skin cancer removal using the BIO-LIVING CELL Therapy.
  • Figure 9 is pictures showing the result of the removal of a slightly bigger skin cancer by using BIO-LIVING CELL Therapy.
  • Figure 10 is the pictures of the result of rough skin and scar treatment using the BIO- LIVING CELL Therapy.
  • Figure 11 is the before-after pictures of the result of sensitive skin treatment using the BIO-LIVING CELL Therapy.
  • Figure 12 is showing the result of acne treatment done by BIO-LIVING CELL Therapy.
  • Figure 13J s the before-after pictures of discolor and Face Corrective treatment using BIO-LIVING CELL Therapy.
  • Figure 14 is the before-after pictures of the result of eye pouch treatment using BIO- LIVING CELL Therapy.
  • Figure 15 is the before-after pictures of infection and scar treatment using the BIO- LIVING CELL Therapy.
  • Figure 16 is showing the result pictures of blemish and scar treatment of BIO- LIVING CELL Therapy.
  • Figure 17 is the before-after pictures of the wrinkle treatment using the BIO-LIVING CELL Therapy.
  • Figure 18 is the before-after pictures of the freckles treatment using the BIO-LIVING CELL Therapy.
  • Figure 19 is the before-after pictures of face lifting treatment by BIO-LIVING CELL Therapy.
  • Figure 20 is the before-after pictures of another case of face lifting using BIO- LIVING CELL Therapy.
  • Figure 21 is the before-after pictures of the result of sensitive, dark eye pouches and wrinkle treatment by BIO-LIVING CELL Therapy.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Developmental Biology & Embryology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biotechnology (AREA)
  • Birds (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne un procédé permettant de traiter des troubles cutanés et consistant à faire pénétrer un liquide amniotique ovin au moyen de l'iontophorèse. La pénétration du fluide amniotique ovin conduit à la production d'un facteur de croissance des fibroblastes (FGF), d'un facteur de croissance de l'humidité naturelle (NMGF) et d'un facteur de croissance des anticorps naturels immuns (NIBGF), qui à son tour conduit à la réparation, au remplacement et à la reconstruction des tissus cutanés. Les troubles cutanés qui peuvent être traités par le procédé décrit incluent le cancer de la peau, y compris un mélanome, la réduction de la cicatrisation et des imperfections, et la prévention du vieillissement précoce.
PCT/AU2008/000106 2007-07-17 2008-01-31 Thérapie cellulaire bio-vivante WO2009009818A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2007100645A AU2007100645A4 (en) 2007-07-17 2007-07-17 Bio-Living Cell Therapy
AU2007100645 2007-07-17

Publications (1)

Publication Number Publication Date
WO2009009818A1 true WO2009009818A1 (fr) 2009-01-22

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AU (1) AU2007100645A4 (fr)
WO (1) WO2009009818A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109833222A (zh) * 2019-04-10 2019-06-04 长沙嘉兰生物科技有限公司 一种羊胚胎素多肽及其制备方法
CN109846804A (zh) * 2019-01-29 2019-06-07 湖南海济药业有限公司 一种提取羊胚胎素的方法及含羊胚胎素的护肤液

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2160285A1 (en) * 1971-11-17 1973-06-29 Metzinger Albert Embryonic serum-based compsn - used as a skin tonic
JPH06345637A (ja) * 1993-06-08 1994-12-20 Nonogawa Shoji Kk 美白剤
WO2001080945A1 (fr) * 2000-04-21 2001-11-01 Doctors Tech Co., Ltd. Administration transdermique d'acide ascorbique

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2160285A1 (en) * 1971-11-17 1973-06-29 Metzinger Albert Embryonic serum-based compsn - used as a skin tonic
JPH06345637A (ja) * 1993-06-08 1994-12-20 Nonogawa Shoji Kk 美白剤
WO2001080945A1 (fr) * 2000-04-21 2001-11-01 Doctors Tech Co., Ltd. Administration transdermique d'acide ascorbique

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109846804A (zh) * 2019-01-29 2019-06-07 湖南海济药业有限公司 一种提取羊胚胎素的方法及含羊胚胎素的护肤液
CN109833222A (zh) * 2019-04-10 2019-06-04 长沙嘉兰生物科技有限公司 一种羊胚胎素多肽及其制备方法

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