WO2008149563A1 - 作用選択的ビタミンd受容体作用剤 - Google Patents
作用選択的ビタミンd受容体作用剤 Download PDFInfo
- Publication number
- WO2008149563A1 WO2008149563A1 PCT/JP2008/050027 JP2008050027W WO2008149563A1 WO 2008149563 A1 WO2008149563 A1 WO 2008149563A1 JP 2008050027 W JP2008050027 W JP 2008050027W WO 2008149563 A1 WO2008149563 A1 WO 2008149563A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- function
- receptor agonist
- vitamin
- selective vitamin
- selective
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009517731A JP5283043B2 (ja) | 2007-06-04 | 2008-01-07 | 作用選択的ビタミンd受容体作用剤 |
US12/601,998 US9278992B2 (en) | 2007-06-04 | 2008-01-07 | Function-selective vitamin D receptor agonist |
EP08702908.8A EP2163557B1 (en) | 2007-06-04 | 2008-01-07 | Function-selective vitamin d receptor agonist |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007147866 | 2007-06-04 | ||
JP2007-147866 | 2007-06-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008149563A1 true WO2008149563A1 (ja) | 2008-12-11 |
Family
ID=40093393
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/050027 WO2008149563A1 (ja) | 2007-06-04 | 2008-01-07 | 作用選択的ビタミンd受容体作用剤 |
Country Status (4)
Country | Link |
---|---|
US (1) | US9278992B2 (ja) |
EP (1) | EP2163557B1 (ja) |
JP (1) | JP5283043B2 (ja) |
WO (1) | WO2008149563A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017131144A1 (ja) * | 2016-01-28 | 2017-08-03 | 国立大学法人お茶の水女子大学 | ビタミンd活性を有するリトコール酸誘導体 |
CN114686450A (zh) * | 2020-12-28 | 2022-07-01 | 苏州引航生物科技有限公司 | 经修饰的维生素d羟化酶突变体及其应用 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX356006B (es) * | 2013-10-18 | 2018-04-24 | Centro De Investig Y Asistencia En Tecnologia Y Diseno Del Estado De Jalisco A C | Proceso para obtener una molécula que sirve como elicitor de péptidos antimicrobianos. |
CN112074274B (zh) | 2018-03-19 | 2024-03-26 | 艾匹赛特制药公司 | 用于治疗因缺钙引起的病状的组合物 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007147866A (ja) | 2005-11-25 | 2007-06-14 | Sony Corp | 自発光表示装置、発光条件制御装置、発光条件制御方法及びプログラム |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3846411A (en) * | 1971-08-04 | 1974-11-05 | Medichemie Ag | Choleretically active esters and salts of bile acids |
-
2008
- 2008-01-07 WO PCT/JP2008/050027 patent/WO2008149563A1/ja active Application Filing
- 2008-01-07 US US12/601,998 patent/US9278992B2/en not_active Expired - Fee Related
- 2008-01-07 JP JP2009517731A patent/JP5283043B2/ja not_active Expired - Fee Related
- 2008-01-07 EP EP08702908.8A patent/EP2163557B1/en not_active Not-in-force
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007147866A (ja) | 2005-11-25 | 2007-06-14 | Sony Corp | 自発光表示装置、発光条件制御装置、発光条件制御方法及びプログラム |
Non-Patent Citations (6)
Title |
---|
ADACHI, R. ET AL.: "Selective activation of vitamin D receptor by lithocholic acid acetate, a bile acid derivative", JOURNAL OF LIPID RESEARCH, vol. 46, 2005, pages 46 - 57, XP008116081 * |
ISHIZAWA, M. ET AL.: "Lithocholic acid derivatives act as selective vitamin D receptor modulators", J LIPID RES, 7 January 2008 (2008-01-07), XP008116082, Retrieved from the Internet <URL:http://www.jlr.org/cgi/ reprint/M700293-J> [retrieved on 20080311] * |
MAKISHIMA, M. ET AL.: "Vitamin D Receptor As an Intestinal Bile Acid Sensor", SCIENCE, vol. 296, 17 May 2002 (2002-05-17), pages 1313 - 1316, XP008116080 * |
NAGPAL, S. ET AL.: "Noncalcemic actions of vitamin D receptor ligands", ENDOCRINE REVIEWS, vol. 26, no. 5, 2005, pages 662 - 687, XP003020911 * |
See also references of EP2163557A4 * |
SHAIKH ET AL.: "Synthesis and mesomorphic behaviour of lithocholic acid derivatives", BULLETIN OF MATERIAL SCIENCE, vol. 26, no. 5, 2003, pages 559 - 563, XP008116077 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017131144A1 (ja) * | 2016-01-28 | 2017-08-03 | 国立大学法人お茶の水女子大学 | ビタミンd活性を有するリトコール酸誘導体 |
CN114686450A (zh) * | 2020-12-28 | 2022-07-01 | 苏州引航生物科技有限公司 | 经修饰的维生素d羟化酶突变体及其应用 |
CN114686450B (zh) * | 2020-12-28 | 2024-04-16 | 苏州引航生物科技有限公司 | 经修饰的维生素d羟化酶突变体及其应用 |
Also Published As
Publication number | Publication date |
---|---|
EP2163557B1 (en) | 2014-10-15 |
JP5283043B2 (ja) | 2013-09-04 |
US9278992B2 (en) | 2016-03-08 |
EP2163557A1 (en) | 2010-03-17 |
EP2163557A4 (en) | 2011-06-22 |
US20100204191A1 (en) | 2010-08-12 |
JPWO2008149563A1 (ja) | 2010-08-19 |
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