WO2008148318A1 - Appareil à réglage autonome pour mesure de flux sanguin cérébral - Google Patents

Appareil à réglage autonome pour mesure de flux sanguin cérébral Download PDF

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Publication number
WO2008148318A1
WO2008148318A1 PCT/CN2008/070839 CN2008070839W WO2008148318A1 WO 2008148318 A1 WO2008148318 A1 WO 2008148318A1 CN 2008070839 W CN2008070839 W CN 2008070839W WO 2008148318 A1 WO2008148318 A1 WO 2008148318A1
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WO
WIPO (PCT)
Prior art keywords
probe
motor
angle
link
motors
Prior art date
Application number
PCT/CN2008/070839
Other languages
English (en)
Chinese (zh)
Inventor
Xiaoyi Wang
Kai Wang
Original Assignee
Shenzhen Delicate Electronics Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Delicate Electronics Co., Ltd. filed Critical Shenzhen Delicate Electronics Co., Ltd.
Publication of WO2008148318A1 publication Critical patent/WO2008148318A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42—Details of probe positioning or probe attachment to the patient
    • A61B8/4209—Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42—Details of probe positioning or probe attachment to the patient
    • A61B8/4209—Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames
    • A61B8/4227—Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames characterised by straps, belts, cuffs or braces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow

Definitions

  • the present invention relates to a cerebral blood flow detecting device, and more particularly to an automatic adjusting device for cerebral blood flow detecting.
  • transcranial Doppler blood flow analyzer also known as “transcranial Doppler cerebral blood flow diagnostic system”, “transcranial Doppler detector”, “transcranial Doppler” Diagnosis and monitoring system “etc.” detection of cerebrovascular signals
  • TCD is a specialized medical device for non-invasive diagnosis and/or monitoring of intracranial and cervical vascular diseases in humans.
  • the position and angle of the probe to adjust the ultrasonic wave to the patient's head are the most. The best state is the key to successful diagnosis and monitoring, and the most difficult part of the entire clinical application process.
  • a probe holder device that holds the probe.
  • the head frame 10a can be fitted to the head of the subject, and the head frame 10a is provided with a fixed arm l la, which can usually be connected by bolts. It is fixed to the headstock 10a (the probe is not shown, only the mounting hole 12a of the probe is shown).
  • the device has the characteristics of a patient suitable for different brain shapes and sizes; the device can fix the probe after manually finding the target blood vessel, eliminating long-distance operation (especially long-range monitoring).
  • the hand-held probe is easily trembled. Any small movements, such as speech, which are susceptible to fatigue and the resulting signal instability. [6] But the main drawback of this device today is that the process of finding the location of the target vessel is still entirely manual.
  • An automatic adjusting device for cerebral blood flow detection comprising a probe and a controller; the device further comprising a motor for adjusting the angle of the probe, and one end connected to the a transmission mechanism connected to the output of the motor at the other end; the probe is mounted on the support member, and the probe is rotatable relative to the support member;
  • the controller is configured to control the motor to adjust an angle of the probe through the transmission mechanism.
  • the device further includes a probe holder for mounting the probe;
  • the front end of the probe is mounted on the support member by elastic damping or through a hard support connection structure, and the rear end of the probe is connected to the transmission mechanism;
  • the motor includes two angle adjustment motors.
  • the hard support connection structure includes a spherical support disposed at a periphery of the probe, and a spherical mounting position provided on the support member to cooperate with the spherical support member; or
  • the hard support connection structure includes a spherical outer casing of the probe itself, and a spherical mounting position provided on the support member that cooperates with the spherical outer casing.
  • the transmission mechanism includes a steering blade mounted on an output of the angle adjustment motor, and a link connected between the steering blade and the probe; and Eccentrically mounted on the steering vane.
  • the connecting rod includes two connecting ends respectively connected to the output of each angle adjusting motor; the other end of the connecting rod is respectively connected to the rear end of the probe, Alternatively, wherein the other end of the first link is connected to the rear end of the probe, and the other end of the second link is connected to the first link.
  • the probe and the angle adjustment motor for adjusting the angle are set as an angle adjustment module, and at least one azimuth motor is disposed on the probe holder for driving the angle adjustment
  • the module adjusts position in the space from the surface being measured.
  • the azimuth motors are set to three.
  • the controller controls the respective motors in a split mode to sequentially adjust each of the motors.
  • the controller controls the respective motors in the same manner, and each of the motors is provided with a control device to adjust the respective motors.
  • An automatic adjusting device for cerebral blood flow detection provided by the present invention can be equipped on a TCD device of an existing probe (the rack), and the probe adjusting operation for finding a blood vessel can be automatically detected by the system, and the system
  • the motor capable of controlling the automatic adjusting device drives the probe to rotate and automatically track and retrieve the blood vessel, thereby solving the defect that the conventional probe frame completely relies on manual adjustment of the probe and cannot automatically recover the blood vessel, thereby reducing the clinical situation.
  • the difficulty of operation, and unlimited clinical applications such as long daytime detection, long-range monitoring, and nighttime monitoring can be implemented.
  • Figures la, lb, and lc are operational schematic diagrams of a single drive motor for the automatic adjustment device for cerebral blood flow detection of the present invention
  • FIG. 2 is a schematic diagram of the working principle of the driving motor for adjusting the angle and direction of the automatic adjusting device for cerebral blood flow detection according to the present invention
  • FIG. 3 is a schematic diagram showing the operation of a driving motor for adjusting a spatial position of an automatic adjusting device for cerebral blood flow detection according to the present invention
  • FIG. 4 is a schematic illustration of another form of probe mounting of an automatic adjustment device for cerebral blood flow detection of the present invention.
  • Figure 5 is a schematic illustration of another form of probe mounting of an automatic adjustment device for cerebral blood flow detection of the present invention.
  • FIG. 6 is a schematic view showing another form of connection of a connecting rod and a probe of an automatic adjusting device for cerebral blood flow detecting according to the present invention
  • FIG. 7 is a schematic structural view of a prior art TCD head frame.
  • the automatic adjustment device for cerebral blood flow detection of the present invention has the basic technical effect of realizing the adjustment process of the automatic control probe, and the automatic control means that the controlled object is controlled by the controller without direct participation of the person. Or the process is automatically carried out according to the predetermined requirements.
  • the controller such as the microcontroller 100 for controlling the motor means consisting of a double probe for controlling the position of the controlled object is a cerebral blood flow may be mounted in the detection probe holder
  • Probe 110 is shown in Figures la, lb and lc.
  • the implementation of the single chip microcomputer 100 of the present invention can be implemented in various ways.
  • a single-chip circuit can be set on the probe frame, and the discriminating result is sent by the TCD host circuit, and the position and angle of the probe can be adjusted by the single-chip circuit, and the control function of the single-chip microcomputer can also be realized in the TCD host circuit.
  • the prior art TCD host circuit can be set as an embedded system or as a PC system.
  • the motor of the present invention is controlled by the single chip microcomputer 100, it can be swung forward or backward or left and right to adjust the angle of the probe 110, as shown in FIGS. 1a, 1b, and 1c, to adjust the angle of the probe 110.
  • a connecting rod 111 is disposed, one end is disposed at a bottom end of the probe 110, and a top end of the probe 110 is disposed on an elastic damping 120, as shown in FIG. 2; the other end of the connecting rod 111 is connected to the steering blade 131 of the motor 130. Up, and eccentrically disposed, as the steering blade of the motor 130 rotates, the angle of the probe 110 on the elastic damping 120 can be varied.
  • the motor 130 is an angle adjustment motor, which is controlled by the single chip microcomputer 100, so that The angle of the probe 110 is arbitrarily adjusted within a predetermined range, and it is detected whether the intensity of the blood flow signal satisfies the requirement.
  • the connecting rod 111 and the steering vane 131 on the motor 130 constitute a transmission mechanism, and it is obvious to those skilled in the art that other transmission mechanisms can be replaced, such as gear transmission and belt transmission, etc., as long as adjustment can be achieved.
  • the angle and position of the probe can be.
  • the automatic adjustment probe technology of the automatic adjustment device for cerebral blood flow detection of the present invention utilizes two orthogonal motors to drive the probe to achieve the purpose of adjusting the position and angle of the probe, thereby realizing the angle adjustment thereof.
  • the angle adjustment module consisting of the probe and the motor for adjusting the angle, as a whole, can additionally use three motors to move in three directions of space. The implementation of the technical solution will be described in detail below.
  • the present invention mounts the front end of the probe 110 on the elastic damping 120 as shown in FIG.
  • the resilient damping 120 is mounted on a support member, such as the rigid housing of the entire automatic adjustment device.
  • the elastic damping 120 acts as a soft support when the probe 110 is rotated.
  • the front end of the probe 110 can also be mounted on a hard support 150 having a spherical shape, as shown in FIG. 4; the hard support 150 is rotatably mounted on the support member 160, and the support member 160 is opened and The spherical mounting position of the hard support 150 fits. After the probe 110 is rotated, the hard support 150 is rotated relative to the support member 160. As shown in Figure 5, the probe 110' is attached to the support member 160 by another hard support connection structure.
  • the outer casing of the probe 110' in the figure is directly formed in a spherical shape, and is opened on the support member 160 in a spherical mounting position in which the spherical outer casing is fitted.
  • the probe 110' is rotated and rotated directly relative to the support member 160.
  • the rear end of the probe 110 is connected to the steering vane 131 of the motor through a link structure.
  • the connecting rod has two connecting ends respectively corresponding to the connecting rods of the output steering blades 131 of each angle adjusting motor, and the other end of each connecting rod is the same
  • the crucible is mounted on the rear end of the probe 110, and acts on the probe 110 by using two-links to drive the probe to rotate.
  • one ends of the two links are respectively connected to each of the steering blades 131, and the other end of the first link 111' is connected to the rear end of the probe 110.
  • the other end of the second connecting rod 111" is connected to the first connecting rod 11 ,, and the combined force of the two connecting rods acts on the probe to drive the probe to rotate.
  • the connecting rod 111 When the motor is driven by the control of the single chip 100 to drive the blade to rotate, the connecting rod 111 will pull the rear end of the probe 110 closer to or away from the fixed position of the motor, and the front end of the probe is damped, and the connecting rod 111 pushes the probe.
  • the rear end of the 110 will inevitably generate a moment such that the probe 110 as a whole has a small angle of contact with the elastic damping 120 as a center of rotation, resulting in an angled inclination.
  • the center of the probe 110 is opposite to the surface to be tested. Displacement is also generated, and the larger the tilt angle of the probe 110, the larger the displacement of the center position, thereby achieving the equivalent effect of moving the probe position.
  • the maximum deflection angle of the probe 110 depends on the distance H between the connecting rod and the blade connection end to the center of the motor (ie, the limit distance that can be pulled or pushed away from the back end of the probe), and the H value can be adjusted by calculation. Obtain the appropriate, desired probe deflection angle.
  • a single motor and linkage can achieve angular variation of the probe in one dimension (ie, one swing direction, front and rear, or left and right).
  • Adding a motor and connecting rod whose rotating center is perpendicular to the rotating center of the original motor can realize another dimension adjustment.
  • the motor is arranged in the vertical direction of the figure, which can make the probe along X and Y.
  • the axial direction is deflected, that is, the probe is tilted in two axial directions (ie, "ten" shape) near its initial position.
  • the superposition effect of the two deflection directions can be obtained, that is, obtaining an arbitrary deflection direction and a certain range of displacement effects in the direction, and the specific effects of the displacement and the angle deflection are required.
  • the operation and control of the microcontroller The operation and control of the microcontroller.
  • the present invention is provided with two angle-adjusted motor ⁇ , any one of which drives the link to move, and the other link has a tendency to hinder this movement, so the connection between the link and the probe should be an active connection. To eliminate this effect and reduce drag. Also, an active connection should be placed between the connecting rod and the steering vane.
  • the motor and the connecting rod of the rotating center in other directions can be continuously increased to achieve more dimensional adjustment.
  • five motors are required, that is, two of them control the pitch angle of the probe (as above), and then the structure shown in Fig. 2 is used as a whole, that is, the angle adjustment module 140, as shown in Fig. 3, another three motors are set. Controlling the overall adjustment of the angle adjustment module in three axial directions, similar to the three-axis adjustment of a machine tool, etc., will not be described in detail herein.
  • the automatic adjusting device of the cerebral blood flow detecting probe frame of the invention needs to be provided with single-chip control to realize the omnidirectional adjustment of the probe 110, namely: the distance from the measured surface; the position relative to the test point on the measured surface; the test angle .
  • the automatic adjusting device of the cerebral blood flow detecting probe frame of the present invention is easy for the structural designer to realize, the difference is that the volume occupied by the adjusting mechanism will increase, and the control circuit and the software become complicated.
  • the device of the invention regards two motors as the most conventional and practical structure, and it should be noted that the setting of the azimuth motor is not necessarily set to three, and if possible, one or two azimuth motors can be set. , used to adjust the position.
  • FIG. 3 The adjustment structure of the angle adjustment module in the automatic adjusting device for cerebral blood flow detection of the present invention is shown in FIG. 3, which includes three azimuth motors 1, 2, 3, and the azimuth motor 1 is used to adjust the angle adjustment module.
  • Azimuth motor 2 is used to adjust the angle adjustment module in the up and down position shown in FIG. 3, and the azimuth motor 3 is used to adjust the moving position of the angle adjustment module on the vertical paper surface shown in FIG.
  • the gears of each azimuth motor and the angle adjustment module can be properly matched by a gear bite.
  • the automatic adjusting device for cerebral blood flow detection of the present invention is equipped with a plurality of motors for adjusting the head frame, and each motor needs to be preset in the single chip control circuit.
  • the control circuit of the single chip of the invention needs to realize the sequence control of the motor, and the more the motor, the more complicated the control.
  • the automatic adjustment device probe holder provided by the invention, according to the automatic control principle and method, can systematically track and monitor the blood flow signal detected by the probe in the actual clinical application process. When the quality of the blood flow signal drops or the signal is lost, the system continuously adjusts the probe position and angle through the probe drive module until the satisfactory blood flow signal is regained.
  • the TCD equipped with the probe (frame) provided by the present invention can automatically perform the probe adjustment operation for finding the blood vessel, and the system can automatically track and retrieve the blood vessel through the automatic adjustment device, thereby solving the traditional problem well.
  • the probe holder relies entirely on the manual adjustment of the probe and the inability to automatically retrieve the blood vessel, which reduces the difficulty of clinical operation, and can carry out various clinical applications such as long daytime detection, long-range monitoring, and nighttime monitoring without limitation.
  • the structure of the above embodiment is not limited to the structure of the present invention.
  • the connecting rod may be a straight shaft or a crankshaft, or may be other
  • the shape can be realized by an equivalent replacement structure such as shrapnel; the installation and adjustment of the probe can add more motors and connecting rods as needed, and can be installed in one plane or different planes, and the adjustable dimension can be Some adjustments are the same; the arrangement of the motors can be that the rotary axes are not perpendicular to each other at any angle; the motor components that control the action can be different types of motors, or can be realized by hydraulic components;
  • the single-chip microcomputer can also use any other device that can control and/or drive the motor to move the motor.
  • the control device can control the multiple motors in two ways: bifurcation and bifurcation. Controlling multiple motors in sequence using only one control unit; ⁇ Using the same method, each motor is equipped with a control The unit, multiple motors can be independently controlled and operated simultaneously.

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  • Health & Medical Sciences (AREA)
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Abstract

L'invention concerne un appareil à réglage autonome destiné à mesurer le flux cérébral sanguin, comprenant une sonde (110) et un contrôleur (100). Cet appareil comprend aussi un moteur (130) permettant de régler l'angle de la sonde, et un mécanisme de transmission avec une extrémité raccordée à cette sonde (110) et l'autre extrémité raccordée à la sortie du moteur. Cette sonde (110) est montée sur un élément de support et cette sonde (110) peut tourner par rapport à cet élément de support. Le contrôleur (100) est utilisé pour commander le moteur (130) afin de régler l'angle de la sonde par le mécanisme de transmission.
PCT/CN2008/070839 2007-06-01 2008-04-29 Appareil à réglage autonome pour mesure de flux sanguin cérébral WO2008148318A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNB2007100746905A CN100566663C (zh) 2007-06-01 2007-06-01 一种脑血流检测探头架
CN200710074690.5 2007-06-01

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WO2008148318A1 true WO2008148318A1 (fr) 2008-12-11

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WO (1) WO2008148318A1 (fr)

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CN103431877B (zh) * 2013-09-04 2015-04-15 中国科学院深圳先进技术研究院 脑血流检测探头支架
EP3369381A1 (fr) * 2017-03-01 2018-09-05 Koninklijke Philips N.V. Agencement de sonde ultrasonore
CN108132305A (zh) * 2017-12-21 2018-06-08 飞依诺科技(苏州)有限公司 一种换能器阵元性能测试的方法和装置
CN209004039U (zh) * 2018-05-07 2019-06-21 深圳市德力凯医疗设备股份有限公司 一种基于环阵探头的经颅多普勒系统
CN208808519U (zh) * 2018-05-07 2019-05-03 深圳市德力凯医疗设备股份有限公司 一种经颅三维脑血管成像系统
CN108814649B (zh) * 2018-07-05 2024-04-05 河南省计量测试科学研究院 多普勒超声诊断仪血流波形模体及校准方法
CN111248863B (zh) * 2020-01-19 2023-01-31 国家康复辅具研究中心 一种诱发人体皮肤充血响应的加压装置
CN112057105B (zh) * 2020-09-11 2021-10-26 中国科学院长春光学精密机械与物理研究所 超声探头压力调整装置
CN114903639B (zh) * 2021-02-09 2024-08-30 上海交通大学医学院附属瑞金医院 一种基于立体定向头架的猕猴脑深部核团电极植入适配装置及方法

Citations (5)

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US5402789A (en) * 1992-11-23 1995-04-04 Capistrano Labs, Inc. Ultrasonic peripheral vascular probe assembly
CN1133166A (zh) * 1995-04-10 1996-10-16 深圳安科高技术有限公司 一种使用经颅多普勒超声技术检测颅内脑血流状态分布的方法及仪器
US6109270A (en) * 1997-02-04 2000-08-29 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Multimodality instrument for tissue characterization
WO2001058337A2 (fr) * 2000-02-09 2001-08-16 Spencer Technologies, Inc. Procede et appareil associant le diagnostic par ultrason a la therapie par ultrason de façon a ameliorer les thrombolyses
US6663571B1 (en) * 2002-05-28 2003-12-16 Philip Chidi Njemanze Transcranial doppler ultrasound device for odor evaluation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5402789A (en) * 1992-11-23 1995-04-04 Capistrano Labs, Inc. Ultrasonic peripheral vascular probe assembly
CN1133166A (zh) * 1995-04-10 1996-10-16 深圳安科高技术有限公司 一种使用经颅多普勒超声技术检测颅内脑血流状态分布的方法及仪器
US6109270A (en) * 1997-02-04 2000-08-29 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Multimodality instrument for tissue characterization
WO2001058337A2 (fr) * 2000-02-09 2001-08-16 Spencer Technologies, Inc. Procede et appareil associant le diagnostic par ultrason a la therapie par ultrason de façon a ameliorer les thrombolyses
US6663571B1 (en) * 2002-05-28 2003-12-16 Philip Chidi Njemanze Transcranial doppler ultrasound device for odor evaluation

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CN101313854A (zh) 2008-12-03

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