WO2008143171A1 - 糞便中ヘリコバクター・ピロリ抗原の定量的測定により胃粘膜の状態を判断する方法 - Google Patents

糞便中ヘリコバクター・ピロリ抗原の定量的測定により胃粘膜の状態を判断する方法 Download PDF

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Publication number
WO2008143171A1
WO2008143171A1 PCT/JP2008/059027 JP2008059027W WO2008143171A1 WO 2008143171 A1 WO2008143171 A1 WO 2008143171A1 JP 2008059027 W JP2008059027 W JP 2008059027W WO 2008143171 A1 WO2008143171 A1 WO 2008143171A1
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WO
WIPO (PCT)
Prior art keywords
helicobacter pylori
quantifying
gastric mucosal
subject
feces
Prior art date
Application number
PCT/JP2008/059027
Other languages
English (en)
French (fr)
Inventor
Toshihiro Ohtsu
Shigeru Taniguchi
Naomi Uemura
Yasuhiro Koga
Atsushi Takagi
Kazuhiko Inoue
Shigemi Nakajima
Takashi Kawai
Original Assignee
Meiji Dairies Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Dairies Corporation filed Critical Meiji Dairies Corporation
Priority to CN200880016412A priority Critical patent/CN101680899A/zh
Priority to JP2009515206A priority patent/JP5437062B2/ja
Publication of WO2008143171A1 publication Critical patent/WO2008143171A1/ja

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56922—Campylobacter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/062—Gastritis or peptic ulcer disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

　本発明の課題は、被験者の負担が少なく簡便に実施することができ、かつ、見逃し例の割合が極めて少ない、胃粘膜の状態を病態およびその程度とともに胃癌に罹患している危険率あるいは将来罹患する危険率についても詳細に細分化することが可能な、胃粘膜の状態を判断するための方法を提供することにある。また、各病態の判断に関連して胃内に存在するヘリコバクター・ピロリの菌量を定量するための方法をも提供することにある。 　前記課題は、対象の糞便中に存在するヘリコバクター・ピロリ抗原の定量的測定値を指標として、前記対象の胃粘膜の状態を判断する方法および前記対象の胃内に存在するヘリコバクター・ピロリの菌量を定量する方法により解決される。
PCT/JP2008/059027 2007-05-17 2008-05-16 糞便中ヘリコバクター・ピロリ抗原の定量的測定により胃粘膜の状態を判断する方法 WO2008143171A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN200880016412A CN101680899A (zh) 2007-05-17 2008-05-16 通过粪便中幽门螺杆菌抗原的定量测定来判断胃粘膜状态的方法
JP2009515206A JP5437062B2 (ja) 2007-05-17 2008-05-16 糞便中ヘリコバクター・ピロリ抗原の定量的測定により胃粘膜の状態を判断する方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007131953 2007-05-17
JP2007-131953 2007-05-17

Publications (1)

Publication Number Publication Date
WO2008143171A1 true WO2008143171A1 (ja) 2008-11-27

Family

ID=40031873

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/059027 WO2008143171A1 (ja) 2007-05-17 2008-05-16 糞便中ヘリコバクター・ピロリ抗原の定量的測定により胃粘膜の状態を判断する方法

Country Status (3)

Country Link
JP (1) JP5437062B2 (ja)
CN (1) CN101680899A (ja)
WO (1) WO2008143171A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017032550A (ja) * 2015-07-30 2017-02-09 大塚製薬株式会社 胃粘膜萎縮の有無を判定する方法
WO2021187406A1 (ja) * 2020-03-16 2021-09-23 栄研化学株式会社 ヘリコバクター・ピロリ検出用抗体

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104142399B (zh) * 2013-05-08 2016-03-02 北京美康生物技术研究中心有限责任公司 一种利用胶体金免疫层析技术定量检测血清胃蛋白酶原的试纸条及其制备方法和应用
CN106018792B (zh) * 2016-05-17 2018-02-13 北京美康基因科学股份有限公司 一种胃功能检测用免疫层析试剂盒及其制备方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
INOUE K. ET AL.: "Funbenchu Helicobacter Pylori Kogen Kensa wa Iken(Ken)shin ni Oyo Kano ka? Onajihi ni Okonatta Naishikyo Kensa Oyobi Pepsinogen no Hikaku yori", JOURNAL OF GASTROENTEROLOGICAL MASS SURVEY, vol. 43, no. 6, 2005, pages 623 - 629 *
MUKOBAYASHI C. ET AL.: "Kessei Pepsinogen Kensa ni yoru Igan Kenshin - Yori Koritsuteki na Igan Kenshin o Mezashite -", DAI 93 KAI THE JAPANESE SOCIETY OF GASTROENTEROLOGY SOKAI SHOROKUSHU, 20 March 2007 (2007-03-20), pages A29 + ABSTR. NO. 026 *
TAKAGI A.: "Atarashii Rinsho Kensa Mirai no Rinsho Kensa 5. Kansensho Kensa 1 Helicobacter Pylori Kanren Kensa", KENSA TO GIJUTSU, vol. 34, no. 11, 2006, pages 1242 - 1243 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017032550A (ja) * 2015-07-30 2017-02-09 大塚製薬株式会社 胃粘膜萎縮の有無を判定する方法
WO2021187406A1 (ja) * 2020-03-16 2021-09-23 栄研化学株式会社 ヘリコバクター・ピロリ検出用抗体

Also Published As

Publication number Publication date
JP5437062B2 (ja) 2014-03-12
CN101680899A (zh) 2010-03-24
JPWO2008143171A1 (ja) 2010-08-05

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