WO2008136510A1 - 自己免疫性膵炎及び劇症１型糖尿病の検査方法及び検査試薬 - Google Patents

自己免疫性膵炎及び劇症１型糖尿病の検査方法及び検査試薬 Download PDF

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Publication number
WO2008136510A1
WO2008136510A1 PCT/JP2008/058413 JP2008058413W WO2008136510A1 WO 2008136510 A1 WO2008136510 A1 WO 2008136510A1 JP 2008058413 W JP2008058413 W JP 2008058413W WO 2008136510 A1 WO2008136510 A1 WO 2008136510A1
Authority
WO
WIPO (PCT)
Prior art keywords
detection
diabetes
autoimmune pancreatitis
detection method
antibody
Prior art date
Application number
PCT/JP2008/058413
Other languages
English (en)
French (fr)
Inventor
Tetsuro Kobayashi
Toyoshi Endo
Atsushi Sakuraoka
Original Assignee
University Of Yamanashi
Cosmic Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Yamanashi, Cosmic Corporation filed Critical University Of Yamanashi
Priority to EP08752318A priority Critical patent/EP2154536B1/en
Priority to AT08752318T priority patent/ATE526584T1/de
Priority to US12/598,416 priority patent/US8278119B2/en
Publication of WO2008136510A1 publication Critical patent/WO2008136510A1/ja

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • G01N2333/926—Hydrolases (3) acting on glycosyl compounds (3.2) acting on alpha -1, 4-glucosidic bonds, e.g. hyaluronidase, invertase, amylase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

検体中の、アミラーゼα２－Ａと免疫学的に反応する抗体を検出することによりAIPもしくはFT1DMを検査する、または、FT1DMの発症可能性を判定する。この抗体の検出は、例えば、この抗体と免疫学的に反応する抗原を用いる免疫学的方法により行われる。抗原は、好ましくは、ヒトアミラーゼα２－Ａのアミノ酸配列のアミノ酸番号２９９～５１２を含む部分断片である。
PCT/JP2008/058413 2007-05-02 2008-05-02 自己免疫性膵炎及び劇症１型糖尿病の検査方法及び検査試薬 WO2008136510A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP08752318A EP2154536B1 (en) 2007-05-02 2008-05-02 Detection method and detection reagent for autoimmune pancreatitis or fulminant type-1 diabetes
AT08752318T ATE526584T1 (de) 2007-05-02 2008-05-02 Nachweisverfahren und nachweisreagens für autoimmune pankreatitis oder fulminanten typ-1- diabetes
US12/598,416 US8278119B2 (en) 2007-05-02 2008-05-02 Detection method and detection reagent for autoimmune pancreatitis or fulminant type-1 diabetes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007121461A JP4922057B2 (ja) 2007-05-02 2007-05-02 自己免疫性膵炎及び劇症１型糖尿病の検査方法及び検査試薬
JP2007-121461 2007-05-02

Publications (1)

Publication Number Publication Date
WO2008136510A1 true WO2008136510A1 (ja) 2008-11-13

Family

ID=39943614

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/058413 WO2008136510A1 (ja) 2007-05-02 2008-05-02 自己免疫性膵炎及び劇症１型糖尿病の検査方法及び検査試薬

Country Status (5)

Country Link
US (1) US8278119B2 (ja)
EP (1) EP2154536B1 (ja)
JP (1) JP4922057B2 (ja)
AT (1) ATE526584T1 (ja)
WO (1) WO2008136510A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012225941A (ja) * 2012-08-20 2012-11-15 Univ Of Yamanashi 劇症１型糖尿病の検査方法及び検査試薬
CN103808924A (zh) * 2014-02-24 2014-05-21 北京工业大学 一种Th17免疫相关因子与IgG4抗体组合物及其应用

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012012051A2 (en) * 2010-07-20 2012-01-26 Trustees Of Dartmouth College Method for multicolor codetection of microrna and proteins
US8580513B2 (en) 2010-07-20 2013-11-12 Trustees Of Dartmouth College Methods for determining response to neoadjuvant therapy and survival using MicroRNA-10b
WO2013155476A1 (en) * 2012-04-12 2013-10-17 Integrative Enzymatics, Inc. Composition and method for modulating inflammatory molecules with amylase
JP6431721B2 (ja) * 2014-08-13 2018-11-28 学校法人大阪医科薬科大学 劇症１型糖尿病の検出方法及びバイオマーカー並びにキット

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005253434A (ja) * 2004-03-15 2005-09-22 Hokkaido Technology Licence Office Co Ltd ２型糖尿病の診断方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030186345A1 (en) * 2003-01-30 2003-10-02 Hortin Glen L. Macromolecular enzyme substrates
EP1775590A1 (en) * 2005-10-11 2007-04-18 Laboratorios S.A.L.V.A.T., S.A. Non-invasive in vitro method to detect transitional cell carcinoma of the bladder
US20080166741A1 (en) * 2007-01-05 2008-07-10 Industrial Technology Research Institute Method for Diagnosing Membranous Glomerulonephritis Disease and a Kit Thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005253434A (ja) * 2004-03-15 2005-09-22 Hokkaido Technology Licence Office Co Ltd ２型糖尿病の診断方法

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
"Autoimmune pancreatitis diagnostic criteria", 2002, JAPAN PANCREAS SOCIETY
"Fulminant type 1 diabetes mellitus diagnostic criteria", 2004, THE JAPAN DIABETES SOCIETY
DIABETES CARE, vol. 24, 2001, pages 1661 - 7
J. GASTROENTEROL., vol. 36, 2001, pages 293 - 302
N. ENGL. J. MED., vol. 344, 2001, pages 732 - 8
NAKAJO ET AL.: "Hi Jiko Men'ekisei Gekisho 1 Gata Tonyobyo no Rinshozo o Teishita ga Ko GAD Kotai ga Yosei de atta 1 Rei", THE JOURNAL OF THE JAPAN DIABETIC SOCIETY, vol. 46, no. 2, 2003, pages 125 - 128, XP008118271 *
TODD ET AL.: "An Experimental Model of Autoimmune Pancreatitis in the Rat", AMERICAN JOURNAL OF PATHOLOGY, vol. 166, 2005, pages 729 - 736, XP008123657 *
WISE ET AL., J. MOL. BIOL. MED., vol. 2, 1984, pages 307 - 322

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012225941A (ja) * 2012-08-20 2012-11-15 Univ Of Yamanashi 劇症１型糖尿病の検査方法及び検査試薬
CN103808924A (zh) * 2014-02-24 2014-05-21 北京工业大学 一种Th17免疫相关因子与IgG4抗体组合物及其应用
CN103808924B (zh) * 2014-02-24 2016-03-09 北京工业大学 一种Th17免疫相关因子与IgG4抗体组合物及其应用

Also Published As

Publication number Publication date
ATE526584T1 (de) 2011-10-15
EP2154536B1 (en) 2011-09-28
JP4922057B2 (ja) 2012-04-25
JP2008275527A (ja) 2008-11-13
US8278119B2 (en) 2012-10-02
EP2154536A1 (en) 2010-02-17
EP2154536A4 (en) 2010-05-26
US20100129832A1 (en) 2010-05-27

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