WO2008126785A1 - 有用物質の製造法 - Google Patents
有用物質の製造法 Download PDFInfo
- Publication number
- WO2008126785A1 WO2008126785A1 PCT/JP2008/056760 JP2008056760W WO2008126785A1 WO 2008126785 A1 WO2008126785 A1 WO 2008126785A1 JP 2008056760 W JP2008056760 W JP 2008056760W WO 2008126785 A1 WO2008126785 A1 WO 2008126785A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- useful substance
- culture medium
- medium
- protein
- activity
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
本発明により、配列番号1で表されるアミノ酸配列を有する蛋白質、または該蛋白質のホモログの活性が親株より低下、または喪失している微生物を培地中で培養し、培養物中に有用物質を生成、蓄積させ、該培養物中より該有用物質を採取することを特徴とする有用物質の製造法、および配列番号1で表されるアミノ酸配列を有する蛋白質、または該蛋白質のホモログの活性が親株より低下、または喪失している微生物の培養物または該培養物の処理物、ATPをエネルギー源として有用物質を生成する活性を有する酵素または該活性を有する細胞の培養物または該培養物の処理物、炭素源、および該有用物質の前駆物質を媒体中に共存せしめ、該媒体中に有用物質を生成、蓄積させ、該媒体中より該有用物質を採取することを特徴とする有用物質の製造法が提供される。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009509319A JPWO2008126785A1 (ja) | 2007-04-06 | 2008-04-04 | 有用物質の製造法 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007099955 | 2007-04-06 | ||
JP2007-099955 | 2007-04-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008126785A1 true WO2008126785A1 (ja) | 2008-10-23 |
Family
ID=39863884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/056760 WO2008126785A1 (ja) | 2007-04-06 | 2008-04-04 | 有用物質の製造法 |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPWO2008126785A1 (ja) |
WO (1) | WO2008126785A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013505714A (ja) * | 2009-09-24 | 2013-02-21 | ユセベ ファルマ ソシエテ アノニム | シャペロン活性を保持するプロテアーゼ欠損DegP並びにノックアウトTsp及びptr遺伝子を持つ、組換えタンパク質発現のための細菌株 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007037301A1 (ja) * | 2005-09-29 | 2007-04-05 | Kyowa Hakko Kogyo Co., Ltd. | 有用物質の製造法 |
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2008
- 2008-04-04 JP JP2009509319A patent/JPWO2008126785A1/ja not_active Withdrawn
- 2008-04-04 WO PCT/JP2008/056760 patent/WO2008126785A1/ja active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007037301A1 (ja) * | 2005-09-29 | 2007-04-05 | Kyowa Hakko Kogyo Co., Ltd. | 有用物質の製造法 |
Non-Patent Citations (1)
Title |
---|
JONES W.R. ET AL.: "Altered growth-rate-dependent regulation of 6-phosphogluconate dehydrogenase level in hisT mutants of Salmonella typhimurium and Escherichia coli", J. BACTERIOL., vol. 172, no. 3, 1990, pages 1197 - 1205 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013505714A (ja) * | 2009-09-24 | 2013-02-21 | ユセベ ファルマ ソシエテ アノニム | シャペロン活性を保持するプロテアーゼ欠損DegP並びにノックアウトTsp及びptr遺伝子を持つ、組換えタンパク質発現のための細菌株 |
JP2016116517A (ja) * | 2009-09-24 | 2016-06-30 | ユセベ ファルマ ソシエテ アノニム | シャペロン活性を保持するプロテアーゼ欠損DegP並びにノックアウトTsp及びptr遺伝子を持つ、組換えタンパク質発現のための細菌株 |
Also Published As
Publication number | Publication date |
---|---|
JPWO2008126785A1 (ja) | 2010-07-22 |
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