WO2008117775A1 - Taxanes ayant une structure de cycle oxétane - Google Patents
Taxanes ayant une structure de cycle oxétane Download PDFInfo
- Publication number
- WO2008117775A1 WO2008117775A1 PCT/JP2008/055428 JP2008055428W WO2008117775A1 WO 2008117775 A1 WO2008117775 A1 WO 2008117775A1 JP 2008055428 W JP2008055428 W JP 2008055428W WO 2008117775 A1 WO2008117775 A1 WO 2008117775A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- taxanes
- ring structure
- oxetane ring
- cancer
- represented
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention propose de nouveaux agents anticancéreux de taxane extrêmement sûrs qui présentent une activité antitumorale élevée. L'invention concerne des taxanes ayant une structure de cycle oxétane qui sont représentés par la formule générale (1) ; des médicaments contenant les taxanes ; des compositions pharmaceutiques contenant les taxanes ; et un procédé de traitement du cancer avec les taxanes. (1)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007081742 | 2007-03-27 | ||
JP2007-081742 | 2007-03-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008117775A1 true WO2008117775A1 (fr) | 2008-10-02 |
Family
ID=39788510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/055428 WO2008117775A1 (fr) | 2007-03-27 | 2008-03-24 | Taxanes ayant une structure de cycle oxétane |
Country Status (2)
Country | Link |
---|---|
TW (1) | TW200901967A (fr) |
WO (1) | WO2008117775A1 (fr) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07233159A (ja) * | 1993-12-20 | 1995-09-05 | Dai Ichi Seiyaku Co Ltd | タキソール誘導体 |
JPH08503219A (ja) * | 1992-11-13 | 1996-04-09 | フロリダ・ステート・ユニバーシティー | アルキル置換側鎖を有するタキサンおよびそれを含有する薬剤組成物 |
JPH0912578A (ja) * | 1995-04-28 | 1997-01-14 | Dai Ichi Seiyaku Co Ltd | 五環性化合物 |
WO1999037631A1 (fr) * | 1998-01-26 | 1999-07-29 | Hanmi Pharmaceutical Co., Ltd. | Nouveaux composes de taxaneterpine |
WO2007049575A1 (fr) * | 2005-10-25 | 2007-05-03 | Daiichi Sankyo Company, Limited | Composé du taxane ayant une structure cyclique d'azétidine |
-
2008
- 2008-03-24 WO PCT/JP2008/055428 patent/WO2008117775A1/fr active Application Filing
- 2008-03-26 TW TW097110661A patent/TW200901967A/zh unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08503219A (ja) * | 1992-11-13 | 1996-04-09 | フロリダ・ステート・ユニバーシティー | アルキル置換側鎖を有するタキサンおよびそれを含有する薬剤組成物 |
JPH07233159A (ja) * | 1993-12-20 | 1995-09-05 | Dai Ichi Seiyaku Co Ltd | タキソール誘導体 |
JPH0912578A (ja) * | 1995-04-28 | 1997-01-14 | Dai Ichi Seiyaku Co Ltd | 五環性化合物 |
WO1999037631A1 (fr) * | 1998-01-26 | 1999-07-29 | Hanmi Pharmaceutical Co., Ltd. | Nouveaux composes de taxaneterpine |
WO2007049575A1 (fr) * | 2005-10-25 | 2007-05-03 | Daiichi Sankyo Company, Limited | Composé du taxane ayant une structure cyclique d'azétidine |
Non-Patent Citations (1)
Title |
---|
ZHU Q. ET AL.: "Comparative molecular field analysis of a serious of paclitaxel analogs", JOURNAL OF MEDICINAL CHEMISTRY, vol. 40, no. 26, 1997, pages 4319 - 4328 * |
Also Published As
Publication number | Publication date |
---|---|
TW200901967A (en) | 2009-01-16 |
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