WO2008105215A1 - アルコール性肝障害診断用マーカーペプチドおよびそれを利用したアルコール性肝障害診断方法 - Google Patents

アルコール性肝障害診断用マーカーペプチドおよびそれを利用したアルコール性肝障害診断方法 Download PDF

Info

Publication number
WO2008105215A1
WO2008105215A1 PCT/JP2008/051519 JP2008051519W WO2008105215A1 WO 2008105215 A1 WO2008105215 A1 WO 2008105215A1 JP 2008051519 W JP2008051519 W JP 2008051519W WO 2008105215 A1 WO2008105215 A1 WO 2008105215A1
Authority
WO
WIPO (PCT)
Prior art keywords
diagnosis
liver disease
alcoholic liver
same
marker peptide
Prior art date
Application number
PCT/JP2008/051519
Other languages
English (en)
French (fr)
Inventor
Kazuyuki Sogawa
Fumio Nomura
Takeshi Tomonaga
Mamoru Sato
Tatsuya Ohashi
Iwao Kiyokawa
Ryo Kojima
Katsuhiro Katayama
Original Assignee
Nitto Boseki Co., Ltd.
National University Corporation Chiba University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitto Boseki Co., Ltd., National University Corporation Chiba University filed Critical Nitto Boseki Co., Ltd.
Priority to JP2009501157A priority Critical patent/JP5419680B2/ja
Publication of WO2008105215A1 publication Critical patent/WO2008105215A1/ja

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

Abstract

　ヒトフィブリノペプチドＡの分解産物あるいはヒトフィブリノーゲンα－Ｅ鎖の分解産物をマーカーペプチドとして利用することによりアルコール性肝障害を的確にかつ迅速に診断することができる。
PCT/JP2008/051519 2007-02-28 2008-01-31 アルコール性肝障害診断用マーカーペプチドおよびそれを利用したアルコール性肝障害診断方法 WO2008105215A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009501157A JP5419680B2 (ja) 2007-02-28 2008-01-31 アルコール性肝障害診断用マーカーペプチドおよびそれを利用したアルコール性肝障害診断方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-048523 2007-02-28
JP2007048523 2007-02-28

Publications (1)

Publication Number Publication Date
WO2008105215A1 true WO2008105215A1 (ja) 2008-09-04

Family

ID=39721053

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/051519 WO2008105215A1 (ja) 2007-02-28 2008-01-31 アルコール性肝障害診断用マーカーペプチドおよびそれを利用したアルコール性肝障害診断方法

Country Status (2)

Country Link
JP (1) JP5419680B2 (ja)
WO (1) WO2008105215A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011052380A1 (ja) * 2009-10-28 2011-05-05 日東紡績株式会社 ５．９ｋＤａペプチドの免疫学的測定方法
WO2014202955A1 (en) * 2013-06-20 2014-12-24 Neuro-Bio Ltd Biomarkers for alzheimer's disease
ES2537052A1 (es) * 2015-02-27 2015-06-01 Fundación Para La Formación E Investigación Sanitarias De La Región De Murcia Procedimiento para la predicción de cirrosis hepática alcohólica no vírica en un sujeto
JP2017015607A (ja) * 2015-07-02 2017-01-19 学校法人兵庫医科大学 飲酒に伴う高血圧発症の予測用ペプチドおよびそれを用いた飲酒に伴う高血圧発症の予測方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004058966A1 (ja) * 2002-12-24 2004-07-15 Nitto Boseki Co., Ltd. 肝臓疾患診断用マーカー蛋白質およびそれを利用した肝臓疾患診断方法
JP2006308533A (ja) * 2005-05-02 2006-11-09 Mcbi:Kk 新規肝がんバイオマーカーおよび該バイオマーカーを用いた肝がんの検出方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004058966A1 (ja) * 2002-12-24 2004-07-15 Nitto Boseki Co., Ltd. 肝臓疾患診断用マーカー蛋白質およびそれを利用した肝臓疾患診断方法
JP2006308533A (ja) * 2005-05-02 2006-11-09 Mcbi:Kk 新規肝がんバイオマーカーおよび該バイオマーカーを用いた肝がんの検出方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GRAM J. ET AL.: "Increased Levels of Fibrinolysis Reaction Products (D-Dimer) in Patients with Decompensated Alcoholic Liver Cirrhosis", ALCOHOLIC LIVER CIRRHOSIS AND HAEMOSTASIS, vol. 26, no. 11, 1991, pages 1173 - 1178 *

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011052380A1 (ja) * 2009-10-28 2011-05-05 日東紡績株式会社 ５．９ｋＤａペプチドの免疫学的測定方法
CN102597772A (zh) * 2009-10-28 2012-07-18 日东纺绩株式会社 5.9kDa肽的免疫学测定方法
EP2495564A1 (en) * 2009-10-28 2012-09-05 Nitto Boseki Co., Ltd 5.9 kDa PEPTIDE IMMUNOASSAY METHOD
US20120276562A1 (en) * 2009-10-28 2012-11-01 Nitto Boseki Co., Ltd. 5.9 kDa PEPTIDE IMMUNOASSAY METHOD
EP2495564A4 (en) * 2009-10-28 2013-07-10 Nitto Boseki Co Ltd 5.9 kDa PEPTIDE IMMUNOASSAY METHOD
CN102597772B (zh) * 2009-10-28 2014-08-20 日东纺绩株式会社 5.9kDa肽的免疫学测定方法
JP5585587B2 (ja) * 2009-10-28 2014-09-10 日東紡績株式会社 ５．９ｋＤａペプチドの免疫学的測定方法
US9017959B2 (en) 2009-10-28 2015-04-28 Nitto Boseki Co., Ltd. 5.9 kDa peptide immunoassay method
WO2014202955A1 (en) * 2013-06-20 2014-12-24 Neuro-Bio Ltd Biomarkers for alzheimer's disease
ES2537052A1 (es) * 2015-02-27 2015-06-01 Fundación Para La Formación E Investigación Sanitarias De La Región De Murcia Procedimiento para la predicción de cirrosis hepática alcohólica no vírica en un sujeto
JP2017015607A (ja) * 2015-07-02 2017-01-19 学校法人兵庫医科大学 飲酒に伴う高血圧発症の予測用ペプチドおよびそれを用いた飲酒に伴う高血圧発症の予測方法

Also Published As

Publication number Publication date
JP5419680B2 (ja) 2014-02-19
JPWO2008105215A1 (ja) 2010-06-03

Similar Documents

Publication Publication Date Title
WO2010069532A8 (en) Antibodies against human angiopoietin 2
WO2009139817A3 (en) Crystalline pharmaceutical and methods of preparation and use thereof
WO2009021754A3 (en) Monospecific and multispecific antibodies and method of use
WO2008157635A3 (en) Synthetic bile acid composition, method, and preparation
WO2007066232A3 (en) Salts of fatty acids and methods of making and using thereof
WO2007103447A3 (en) A method for the preparation of recombinant human thrombin
ATE441638T1 (de) 4,5-diphenyl-pyrimidinyl substituierte carbonsäuren, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
WO2007093627A3 (de) Biozide zusammensetzung
WO2009126688A8 (en) Novel compositions and methods for the treatment of immune related diseases
WO2011106322A3 (en) Biomarkers for acute ischemic stroke
WO2009149956A3 (en) Fusion protein and use thereof
WO2011066291A3 (en) Lyophilization methods, compositions, and kits
WO2008015015A3 (en) Dendritic polyglycerol sulfates and sulfonates and their use for inflammatory diseases
WO2008035066A3 (en) Processes for the preparation of ciclesonide and its crystal form
WO2009100275A3 (en) Compositions and devices
WO2008049183A8 (en) Method for modifying plant architecture and enhancing plant biomass and/or sucrose yield
WO2009124962A3 (en) Sulfonamides
WO2009035959A3 (en) Radiofluorination methods
WO2008105215A1 (ja) アルコール性肝障害診断用マーカーペプチドおよびそれを利用したアルコール性肝障害診断方法
WO2010098583A3 (ko) 스타틴 화합물 또는 그 염의 신규 제조방법, 및 이에 사용되는 중간체 화합물
WO2008112840A3 (en) Novel composition and methods for the treatment of immune related diseases
WO2011092694A3 (en) Method for improved fibrin sealing
WO2008017636A8 (en) Genes and proteins of brachyspira hyodysenteriae and uses thereof
WO2010057647A3 (en) Methods and compositions for the diagnosis and treatment of diabetes
WO2012042062A3 (de) Markersequenzen für multiple sklerose und deren verwendung

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08704266

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2009501157

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08704266

Country of ref document: EP

Kind code of ref document: A1