WO2008096814A1 - 新規ポリペプチド及びそれを有効成分として含有する抗菌剤 - Google Patents

新規ポリペプチド及びそれを有効成分として含有する抗菌剤 Download PDF

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Publication number
WO2008096814A1
WO2008096814A1 PCT/JP2008/052020 JP2008052020W WO2008096814A1 WO 2008096814 A1 WO2008096814 A1 WO 2008096814A1 JP 2008052020 W JP2008052020 W JP 2008052020W WO 2008096814 A1 WO2008096814 A1 WO 2008096814A1
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WO
WIPO (PCT)
Prior art keywords
antibacterial agent
polypeptide
active ingredient
novel polypeptide
same
Prior art date
Application number
PCT/JP2008/052020
Other languages
English (en)
French (fr)
Inventor
Hironori Nakagami
Tomoyuki Nishikawa
Yasufumi Kaneda
Kazunori Tomono
Akito Maeda
Nao Tamura
Original Assignee
Genomidea Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomidea Inc. filed Critical Genomidea Inc.
Priority to JP2008557152A priority Critical patent/JP5384948B2/ja
Publication of WO2008096814A1 publication Critical patent/WO2008096814A1/ja

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

優れた抗菌活性を有する新規なポリペプチド及びそれを有効成分として含有する抗菌剤が開示されている。特定のアミノ酸配列を有するポリペプチド及びそれを有効成分として含有する抗菌剤が提供された。優れた抗菌活性を有する新規なポリペプチド及びそれを有効成分として含有する抗菌剤が提供された。この抗菌剤は、褥瘡、創傷、皮膚潰瘍、蜂巣炎、急性リンパ管炎、リンパ節炎、丹毒、皮膚膿瘍、壊死性皮下感染、ブドウ球菌性熱傷様 皮膚症候群（SSSS）、毛包炎、フルンケル、化膿性汗腺炎、カルブンケル（癰）、感染性爪囲炎、紅色陰癬、重症感染症（敗血症）等の疾患の処置のための予防、改善又は治療等に優れた効果を発揮する。
PCT/JP2008/052020 2007-02-09 2008-02-07 新規ポリペプチド及びそれを有効成分として含有する抗菌剤 WO2008096814A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008557152A JP5384948B2 (ja) 2007-02-09 2008-02-07 新規ポリペプチド及びそれを有効成分として含有する抗菌剤

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-029920 2007-02-09
JP2007029920 2007-02-09

Publications (1)

Publication Number Publication Date
WO2008096814A1 true WO2008096814A1 (ja) 2008-08-14

Family

ID=39681718

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/052020 WO2008096814A1 (ja) 2007-02-09 2008-02-07 新規ポリペプチド及びそれを有効成分として含有する抗菌剤

Country Status (2)

Country Link
JP (1) JP5384948B2 (ja)
WO (1) WO2008096814A1 (ja)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010061915A1 (ja) * 2008-11-28 2010-06-03 アンジェスＭｇ株式会社 血管新生誘導活性及び抗菌活性を有する新規ポリペプチド並びにその医薬用途
WO2010101237A1 (ja) 2009-03-06 2010-09-10 アンジェスＭｇ株式会社 ポリペプチド及びその抗菌または消毒用途
WO2010137594A1 (ja) * 2009-05-25 2010-12-02 アンジェスＭｇ株式会社 血管新生誘導活性及び抗菌活性を有するポリペプチドおよびそれを含有する創傷治療剤
WO2012101156A3 (en) * 2011-01-26 2013-05-30 Pergamum Ab Human lactoferrin based peptides having antiinflammatory activity
WO2014157485A1 (ja) * 2013-03-29 2014-10-02 国立大学法人大阪大学 抗老化作用を有するペプチドおよびその利用
US10112978B2 (en) 2014-09-26 2018-10-30 Osaka University Peptide and use thereof
CN116217357A (zh) * 2023-03-16 2023-06-06 天津师范大学 一种液态多联苯芳烃及其合成方法与应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003520808A (ja) * 2000-01-21 2003-07-08 ザ バーナム インスティチュート プロアポトーシス活性を有するキメラ前立腺ホーミングペプチド
JP2004526663A (ja) * 2000-06-28 2004-09-02 ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア ノビスピリン抗菌ペプチド
WO2005090564A1 (ja) * 2004-03-19 2005-09-29 Genomidea Inc. 血管内皮増殖促進遺伝子

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0402807D0 (sv) * 2004-11-17 2004-11-17 Dermagen Ab Novel antimicrobial peptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003520808A (ja) * 2000-01-21 2003-07-08 ザ バーナム インスティチュート プロアポトーシス活性を有するキメラ前立腺ホーミングペプチド
JP2004526663A (ja) * 2000-06-28 2004-09-02 ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア ノビスピリン抗菌ペプチド
WO2005090564A1 (ja) * 2004-03-19 2005-09-29 Genomidea Inc. 血管内皮増殖促進遺伝子

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
AURORA R. ET AL.: "Helix capping", PROTEIN SCI., vol. 7, no. 1, 1998, pages 21 - 38 *
D'ANDREA L.D. ET AL.: "Targeting angiogenesis: Structural characterization and biological properties of a de novo engineered VEGF mimicking peptide", PNAS, vol. 102, no. 40, 2005, pages 14215 - 14220, XP002430308 *
NAKAGAMI H. ET AL.: "Shinki Kekkan Shinsei Peptide AG-30 no Kino Kaiseki", THER. RES., vol. 28, no. 3, March 2007 (2007-03-01), pages 367 *
NISHIKAWA T. ET AL.: "Shinki Kekkan Shinsei Peptide AG-30 no Dotei", ANNUAL MEETING OF THE MOLECULAR BIOLOGY SOCIETY OF JAPAN KOEN YOSHISHU, vol. 28TH, 2005, pages 537 + ABSTR. NO. 2P-1132 *

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010061915A1 (ja) * 2008-11-28 2010-06-03 アンジェスＭｇ株式会社 血管新生誘導活性及び抗菌活性を有する新規ポリペプチド並びにその医薬用途
US9376470B2 (en) 2008-11-28 2016-06-28 Funpep Inc. Polypeptide having angiogenesis-inducing activity and antibacterial activity, and use thereof for medical purposes
JP5691049B2 (ja) * 2008-11-28 2015-04-01 アンジェスＭｇ株式会社 血管新生誘導活性及び抗菌活性を有する新規ポリペプチド並びにその医薬用途
US8470765B2 (en) 2009-03-06 2013-06-25 Anges Mg, Inc. Polypeptides and antibacterial or antiseptic use of same
JP5750765B2 (ja) * 2009-03-06 2015-07-22 株式会社ファンペップ ポリペプチド及びその抗菌または消毒用途
WO2010101237A1 (ja) 2009-03-06 2010-09-10 アンジェスＭｇ株式会社 ポリペプチド及びその抗菌または消毒用途
JP2016104726A (ja) * 2009-03-06 2016-06-09 株式会社ファンペップ ポリペプチド及びその抗菌または消毒用途
JPWO2010101237A1 (ja) * 2009-03-06 2012-09-10 アンジェスＭｇ株式会社 ポリペプチド及びその抗菌または消毒用途
JP2015038108A (ja) * 2009-03-06 2015-02-26 アンジェスＭｇ株式会社 ポリペプチド及びその抗菌または消毒用途
US9695219B2 (en) 2009-05-25 2017-07-04 Funpep Inc. Polypeptide having antibacterial activity and angiogenesis-inducing activity and wound-healing drug containing said polypeptide
US20120172287A1 (en) * 2009-05-25 2012-07-05 Anges Mg, Inc. Polypeptide Having Antibacterial Activity and Angiogenesis-Inducing Activity and Wound-Healing Drug Containing Said Polypeptide
JP5750766B2 (ja) * 2009-05-25 2015-07-22 株式会社ファンペップ 血管新生誘導活性及び抗菌活性を有するポリペプチドおよびそれを含有する創傷治療剤
US8969311B2 (en) 2009-05-25 2015-03-03 Anges Mg, Inc. Polypeptide having antibacterial activity and angiogenesis-inducing activity and wound-healing drug containing said polypeptide
WO2010137594A1 (ja) * 2009-05-25 2010-12-02 アンジェスＭｇ株式会社 血管新生誘導活性及び抗菌活性を有するポリペプチドおよびそれを含有する創傷治療剤
US8846608B2 (en) 2011-01-26 2014-09-30 Pergamum Ab Human lactoferrin derived peptides and their use
US9132165B2 (en) 2011-01-26 2015-09-15 Pergamum Ab Synthetic peptides and their use
JP2014505062A (ja) * 2011-01-26 2014-02-27 ペルガモン アクティエボラーグ ヒトラクトフェリン由来ペプチド及びその使用
JP2014505061A (ja) * 2011-01-26 2014-02-27 ペルガモン アクティエボラーグ 新規合成ペプチド及びそれらの使用
AU2012210564B2 (en) * 2011-01-26 2016-10-27 Pergamum Ab Human lactoferrin based peptides having antiinflammatory activity
WO2012101156A3 (en) * 2011-01-26 2013-05-30 Pergamum Ab Human lactoferrin based peptides having antiinflammatory activity
WO2014157485A1 (ja) * 2013-03-29 2014-10-02 国立大学法人大阪大学 抗老化作用を有するペプチドおよびその利用
US9872825B2 (en) 2013-03-29 2018-01-23 Osaka University Peptide with anti-aging effect and use thereof
US10463592B2 (en) 2013-03-29 2019-11-05 Osaka University Peptide with anti-aging effect and use thereof
US10112978B2 (en) 2014-09-26 2018-10-30 Osaka University Peptide and use thereof
US10233215B2 (en) 2014-09-26 2019-03-19 Osaka University Peptide and use thereof
CN116217357A (zh) * 2023-03-16 2023-06-06 天津师范大学 一种液态多联苯芳烃及其合成方法与应用
CN116217357B (zh) * 2023-03-16 2024-05-07 天津师范大学 一种液态多联苯芳烃及其合成方法与应用

Also Published As

Publication number Publication date
JP5384948B2 (ja) 2014-01-08
JPWO2008096814A1 (ja) 2010-05-27

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