WO2008060792A3 - Nouvelles cellules et compositions et nouveaux procédés associés - Google Patents

Nouvelles cellules et compositions et nouveaux procédés associés Download PDF

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Publication number
WO2008060792A3
WO2008060792A3 PCT/US2007/081280 US2007081280W WO2008060792A3 WO 2008060792 A3 WO2008060792 A3 WO 2008060792A3 US 2007081280 W US2007081280 W US 2007081280W WO 2008060792 A3 WO2008060792 A3 WO 2008060792A3
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WO
WIPO (PCT)
Prior art keywords
methods
compositions
novel cells
cells
disclosed
Prior art date
Application number
PCT/US2007/081280
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English (en)
Other versions
WO2008060792A2 (fr
WO2008060792A9 (fr
Inventor
David H Kelly
Original Assignee
Stem Cells Innovations
David H Kelly
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stem Cells Innovations, David H Kelly filed Critical Stem Cells Innovations
Priority to PCT/US2007/081280 priority Critical patent/WO2008060792A2/fr
Publication of WO2008060792A2 publication Critical patent/WO2008060792A2/fr
Publication of WO2008060792A3 publication Critical patent/WO2008060792A3/fr
Publication of WO2008060792A9 publication Critical patent/WO2008060792A9/fr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0611—Primordial germ cells, e.g. embryonic germ cells [EG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/119—Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/41—Hedgehog proteins; Cyclopamine (inhibitor)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/04—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from germ cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Neurosurgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des compositions et des précédés peremettant de produire des cellules et des cellules souches. L'invention concerne également de nouveaux procédés, des cellules souches multipotentes et des banques de cellules souches correspondantes.
PCT/US2007/081280 2006-10-12 2008-04-07 Nouvelles cellules et compositions et nouveaux procédés associés WO2008060792A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/US2007/081280 WO2008060792A2 (fr) 2006-10-12 2008-04-07 Nouvelles cellules et compositions et nouveaux procédés associés

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60/829,172 2006-10-12
US60/829,175 2006-10-12
PCT/US2007/081280 WO2008060792A2 (fr) 2006-10-12 2008-04-07 Nouvelles cellules et compositions et nouveaux procédés associés

Publications (3)

Publication Number Publication Date
WO2008060792A2 WO2008060792A2 (fr) 2008-05-22
WO2008060792A3 true WO2008060792A3 (fr) 2008-12-31
WO2008060792A9 WO2008060792A9 (fr) 2009-02-12

Family

ID=39402357

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/081280 WO2008060792A2 (fr) 2006-10-12 2008-04-07 Nouvelles cellules et compositions et nouveaux procédés associés

Country Status (1)

Country Link
WO (1) WO2008060792A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130149287A1 (en) 2010-07-30 2013-06-13 Cambridge Enterprise Limited Corticogenesis of Human Pluripotent Cells
EP2825637A4 (fr) * 2012-03-14 2015-12-23 Childrens Medical Center Criblage chimique à haut rendement fondé sur l'imagerie, applicable à une culture de cellules de blastomères de poisson-zèbre
TW201900870A (zh) * 2017-05-26 2019-01-01 美商凱特製藥公司 製備和使用胚胎間充質先驅細胞的方法
CN110665059B (zh) * 2019-10-17 2021-09-28 苏州大学 一种组织工程化神经移植体及其制备方法
JP2023516484A (ja) 2020-03-11 2023-04-19 ビット バイオ リミテッド 肝細胞作製方法

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
CHIBA S. ET AL.: "Noggin and Basic FGF were Implicated in Forebrain Fate and Caudal Fate, Respectively, of the Neural Tube-Like Structures Emerging from Mouse ES Cell Culture", EXPERIMENTAL BRAIN RESEARCH, vol. 163, 2005, pages 86 - 99, XP019328842, DOI: doi:10.1007/s00221-004-2148-y *
CHUNG S. ET AL.: "Analysis of Different Promoter Systems for Efficient Transgene Expression in Mouse Embryonic Stem Cell Lines", STEM CELLS, vol. 20, 2002, pages 139 - 145 *
KELVIN D.J. ET AL.: "Growth Factors, Signaling Pathways, and the Regulation of Proliferation and Differentiation in BC3H1 Muscle Cells. I. A Pertussis Toxin-Sensitive Pathway is Involved", JOURNAL OF CELL BIOLOGY, vol. 108, 1 January 1989 (1989-01-01), pages 159 - 167 *
KINOSHITA T. ET AL.: "Hepatic Differentiation Induced by Oncostatin M Attenuates Fetal Liver Hematopoiesis", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA), vol. 96, June 1999 (1999-06-01), pages 7265 - 7270 *
LORENZON P. ET AL.: "Properties of Primary Mouse Myoblasts Expanded in Culture", EXPERIMENTAL CELL RESEARCH, vol. 278, 2002, pages 84 - 91 *
MATINEZ-SERRANO ET AL.: "Immortalized Neural Progenitor Cells for CNS Transfer and Repair", TRENDS IN NEUROSCIENCE, vol. 20, no. 11, 1997, pages 530 - 538, XP002926796, DOI: doi:10.1016/S0166-2236(97)01119-3 *
ROY N.S. ET AL.: "Enhancer-Specified GFP-Based FACS Purification of Human Motor Neurons from Embryonic Stem Cells", EXPERIMENTAL NEUROLOGY, vol. 196, 2005, pages 224 - 234, XP005153370, DOI: doi:10.1016/j.expneurol.2005.06.021 *
SAITO S. ET AL.: "Isolation of Embryonic Stem-Like Cells from Equine Blastocysts and their Differentiation in Vitro", FEBS LETTERS, vol. 531, 2002, pages 389 - 396, XP004392674, DOI: doi:10.1016/S0014-5793(02)03550-0 *
THOMSON J.A. ET AL.: "Embryonic Stem Cell Lines from Human Blastocysts", SCIENCE, vol. 282, 6 November 1998 (1998-11-06), pages 1145 - 1147, XP002933311, DOI: doi:10.1126/science.282.5391.1145 *
WICHTERLE H. ET AL.: "Directed Differentiation of Embryonic Stem Cells into Motor Neurons", CELL, vol. 110, 9 August 2002 (2002-08-09), pages 385 - 397, XP002537463, DOI: doi:10.1016/S0092-8674(02)00835-8 *
XU C. ET AL.: "Basic Fibroblasts Growth Factor Supports Undifferentiated Human Embryonic Stem Cell Growth Without Conditionted Medium", STEM CELLS, vol. 23, 2005, pages 315 - 323 *
YANG W.-F. ET AL.: "Improved Isolation and Culture of Embryonic Germ Cells from Guanzhong Dairy Goat", AGRICULTURAL SCIENCES IN CHINA, vol. 5, no. 7, July 2006 (2006-07-01), pages 550 - 557, XP022855446, DOI: doi:10.1016/S1671-2927(06)60091-6 *

Also Published As

Publication number Publication date
WO2008060792A2 (fr) 2008-05-22
WO2008060792A9 (fr) 2009-02-12

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