WO2008058272A3 - Polymer-based antimicrobial agents, methods of making said agents, and products and applications using said agents - Google Patents

Polymer-based antimicrobial agents, methods of making said agents, and products and applications using said agents Download PDF

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Publication number
WO2008058272A3
WO2008058272A3 PCT/US2007/084269 US2007084269W WO2008058272A3 WO 2008058272 A3 WO2008058272 A3 WO 2008058272A3 US 2007084269 W US2007084269 W US 2007084269W WO 2008058272 A3 WO2008058272 A3 WO 2008058272A3
Authority
WO
WIPO (PCT)
Prior art keywords
agents
metal
water
ions
metal ions
Prior art date
Application number
PCT/US2007/084269
Other languages
French (fr)
Other versions
WO2008058272A2 (en
Inventor
Ashraf A Ismail
Leonard Pinchuk
Orley R Pinchuk
David Pinchuk
Original Assignee
Smart Anti Microbial Solutions
Ashraf A Ismail
Leonard Pinchuk
Orley R Pinchuk
David Pinchuk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/558,027 external-priority patent/US20070087023A1/en
Priority claimed from US11/558,023 external-priority patent/US7951853B2/en
Application filed by Smart Anti Microbial Solutions, Ashraf A Ismail, Leonard Pinchuk, Orley R Pinchuk, David Pinchuk filed Critical Smart Anti Microbial Solutions
Priority to MX2009004968A priority Critical patent/MX2009004968A/en
Priority to EP07871421A priority patent/EP2086511A4/en
Priority to CA002669334A priority patent/CA2669334A1/en
Priority to AU2007317253A priority patent/AU2007317253A1/en
Priority to BRPI0718703-3A priority patent/BRPI0718703A2/en
Publication of WO2008058272A2 publication Critical patent/WO2008058272A2/en
Publication of WO2008058272A3 publication Critical patent/WO2008058272A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10Macromolecular compounds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/14Boron; Compounds thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/16Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/16Heavy metals; Compounds thereof
    • A01N59/20Copper
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015Drug-containing film-forming compositions, e.g. spray-on

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Dispersion Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

The present invention relates to antimicrobial agents, methods for the production of these agents, and the use of these agents. The antimicrobial agent of the present invention includes a water-soluble polymer and oligodynamic metal ions which interact with counter-ions of the polymer such that the metal ions are bound to corresponding counter-ions. The water-soluble polymer controls a sustained release of the metal ions. The oligodynamic metal ions preferably include small size metal particles (e.g., nano-sized silver particles) that interact to the water-soluble polymer as well as metal ions derived from one or more water-soluble oligodynamic metal compositions (e.g., metal sulfates and/or metal nitrates). The agent may also include one or more acids, including organic acids (such as sulfates, carboxylic acids, amines, hydroxyls, nitrates, and phosphates) and/or non-organic acids (such as boric acid and dioctylborate).
PCT/US2007/084269 2006-11-09 2007-11-09 Polymer-based antimicrobial agents, methods of making said agents, and products and applications using said agents WO2008058272A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
MX2009004968A MX2009004968A (en) 2006-11-09 2007-11-09 Polymer-based antimicrobial agents, methods of making said agents, and products and applications using said agents.
EP07871421A EP2086511A4 (en) 2006-11-09 2007-11-09 Polymer-based antimicrobial agents, methods of making said agents, and products and applications using said agents
CA002669334A CA2669334A1 (en) 2006-11-09 2007-11-09 Polymer-based antimicrobial agents, methods of making said agents, and products and applications using said agents
AU2007317253A AU2007317253A1 (en) 2006-11-09 2007-11-09 Polymer-based antimicrobial agents, methods of making said agents, and products and applications using said agents
BRPI0718703-3A BRPI0718703A2 (en) 2006-11-09 2007-11-09 POLYMER-BASED ANTIMICROBIAN AGENTS, METHODS FOR MANUFACTURING SUCH AGENTS AND PRODUCTS AND APPLICATIONS USING THESE AGENTS

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11/558,027 US20070087023A1 (en) 2005-03-11 2006-11-09 Polymer-Based Antimicrobial Agents, Methods of Making Said Agents, and Applications Using Said Agents
US11/558,027 2006-11-09
US11/558,023 2006-11-09
US11/558,023 US7951853B2 (en) 2002-05-02 2006-11-09 Polymer-based antimicrobial agents, methods of making said agents, and products incorporating said agents

Publications (2)

Publication Number Publication Date
WO2008058272A2 WO2008058272A2 (en) 2008-05-15
WO2008058272A3 true WO2008058272A3 (en) 2008-10-02

Family

ID=39365394

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/084269 WO2008058272A2 (en) 2006-11-09 2007-11-09 Polymer-based antimicrobial agents, methods of making said agents, and products and applications using said agents

Country Status (7)

Country Link
EP (1) EP2086511A4 (en)
AU (1) AU2007317253A1 (en)
BR (1) BRPI0718703A2 (en)
CA (1) CA2669334A1 (en)
CO (1) CO6210718A2 (en)
MX (1) MX2009004968A (en)
WO (1) WO2008058272A2 (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030185889A1 (en) * 2002-03-27 2003-10-02 Jixiong Yan Colloidal nanosilver solution and method for making the same
US20040010215A1 (en) * 1997-11-14 2004-01-15 Gibbins Bruce L. Silver-containing compositions, devices and methods for making
US6716895B1 (en) * 1999-12-15 2004-04-06 C.R. Bard, Inc. Polymer compositions containing colloids of silver salts
US6905711B1 (en) * 2002-05-02 2005-06-14 Smart Anti-Microbial Solutions, Llc Antimicrobial agents, products incorporating said agents and methods of making products incorporating antimicrobial agents
US20050266981A1 (en) * 2004-05-28 2005-12-01 Masayuki Nakajima Hydrophilic compositions, methods for their production, and substrates coated with such compositions
US20060147549A1 (en) * 2004-12-30 2006-07-06 Grab Lawrence A Methods and compositions for reducing population of plant pathogen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005329045A1 (en) * 2005-03-11 2006-09-21 Smart Anti-Microbal Solutions, Llc Polymer-based antimicrobial agents, methods of making said agents, and products incorporating said agents

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040010215A1 (en) * 1997-11-14 2004-01-15 Gibbins Bruce L. Silver-containing compositions, devices and methods for making
US6716895B1 (en) * 1999-12-15 2004-04-06 C.R. Bard, Inc. Polymer compositions containing colloids of silver salts
US20030185889A1 (en) * 2002-03-27 2003-10-02 Jixiong Yan Colloidal nanosilver solution and method for making the same
US6905711B1 (en) * 2002-05-02 2005-06-14 Smart Anti-Microbial Solutions, Llc Antimicrobial agents, products incorporating said agents and methods of making products incorporating antimicrobial agents
US20050266981A1 (en) * 2004-05-28 2005-12-01 Masayuki Nakajima Hydrophilic compositions, methods for their production, and substrates coated with such compositions
US20060147549A1 (en) * 2004-12-30 2006-07-06 Grab Lawrence A Methods and compositions for reducing population of plant pathogen

Also Published As

Publication number Publication date
CO6210718A2 (en) 2010-10-20
AU2007317253A1 (en) 2008-05-15
WO2008058272A2 (en) 2008-05-15
MX2009004968A (en) 2009-08-12
CA2669334A1 (en) 2008-05-15
EP2086511A2 (en) 2009-08-12
EP2086511A4 (en) 2012-07-04
BRPI0718703A2 (en) 2014-01-07

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