WO2008040357A1 - Réticulation de mousses de kératine s-sulfonée - Google Patents

Réticulation de mousses de kératine s-sulfonée Download PDF

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Publication number
WO2008040357A1
WO2008040357A1 PCT/DK2007/050134 DK2007050134W WO2008040357A1 WO 2008040357 A1 WO2008040357 A1 WO 2008040357A1 DK 2007050134 W DK2007050134 W DK 2007050134W WO 2008040357 A1 WO2008040357 A1 WO 2008040357A1
Authority
WO
WIPO (PCT)
Prior art keywords
keratin
foam
cross
linked
foams
Prior art date
Application number
PCT/DK2007/050134
Other languages
English (en)
Inventor
Jens Hoeg Truelsen
Pia Nielsen
Original Assignee
Coloplast A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coloplast A/S filed Critical Coloplast A/S
Priority to CA002665253A priority Critical patent/CA2665253A1/fr
Priority to AU2007304585A priority patent/AU2007304585A1/en
Priority to EP07817933A priority patent/EP2079787A1/fr
Publication of WO2008040357A1 publication Critical patent/WO2008040357A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/36—After-treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2389/00—Characterised by the use of proteins; Derivatives thereof
    • C08J2389/04—Products derived from waste materials, e.g. horn, hoof or hair

Definitions

  • Foams in the form of scaffolds are guiding structures used for wound care applications resulting in development of new tissue. They are usually made up of biomaterials and are added to tissue to guide the organization, growth and differentiation of cells in the process of forming functional tissue.
  • Soft, flexible, absorbent and coherent keratin foams are in general needed for ensuring a comfortable and proper treatment of difficult-to-heal wounds and as releasing media for active ingredients such as growth factors.
  • the present invention relates to a process for cross-linking of a highly porous foam of S-sulfonated keratin, said process comprising the steps of
  • the invention also relates to the use of a cross-linked keratin foam as defined herein for the preparation of a scaffold for supporting cell adhesion or the in-growth for regeneration of tissue, and to the use of a cross-linked keratin foam as defined herein for the preparation of a scaffold adapted for wound care applications.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)

Abstract

La présente invention concerne un procédé pour réticuler des mousses hautement poreuses de kératine S-sulfonée, et des mousses de kératine réticulées, hautement poreuses (par exemple des scaffolds) en tant que tels. De tels scaffolds (mousses) sont particulièrement utiles pour soigner les plaies. De telles mousses de kératine poreuses peuvent être obtenues par en remplaçant la solution aqueuse du réducteur comme milieu de réticulation par une solution alcoolique du même réducteur, et en remplaçant les procédures de lavage aqueux par une procédure similaire de lavage avec un alcool.
PCT/DK2007/050134 2006-10-02 2007-10-02 Réticulation de mousses de kératine s-sulfonée WO2008040357A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002665253A CA2665253A1 (fr) 2006-10-02 2007-10-02 Reticulation de mousses de keratine s-sulfonee
AU2007304585A AU2007304585A1 (en) 2006-10-02 2007-10-02 Cross-linking of foams of S-sulfonated keratin
EP07817933A EP2079787A1 (fr) 2006-10-02 2007-10-02 Réticulation de mousses de kératine s-sulfonée

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200601269 2006-10-02
DKPA200601269 2006-10-02

Publications (1)

Publication Number Publication Date
WO2008040357A1 true WO2008040357A1 (fr) 2008-04-10

Family

ID=37946243

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2007/050134 WO2008040357A1 (fr) 2006-10-02 2007-10-02 Réticulation de mousses de kératine s-sulfonée

Country Status (4)

Country Link
EP (1) EP2079787A1 (fr)
AU (1) AU2007304585A1 (fr)
CA (1) CA2665253A1 (fr)
WO (1) WO2008040357A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9045600B2 (en) 2009-05-13 2015-06-02 Keraplast Technologies, Ltd. Biopolymer materials
US11505587B2 (en) * 2013-01-18 2022-11-22 Nanyang Technological University Method of preparing a keratin-based biomaterial and keratin-based biomaterial formed thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999026570A1 (fr) * 1997-11-26 1999-06-03 Keraplast Technologies, Ltd. Technique de reticulation de film, de feuilles et de materiau en vrac a base de keratine
WO2003018673A1 (fr) * 2001-08-31 2003-03-06 Keratec Limited Production de materiaux biopolymeres sous forme de films, de fibres, de mousses ou d'adhesifs, a partir de derives de keratine s-sulfonee
WO2003103737A1 (fr) * 2002-06-10 2003-12-18 Wool Research Organisaton Of New Zealand (Inc) Materiaux orthopediques derives de la keratine
WO2005058380A1 (fr) * 2003-12-19 2005-06-30 Keratec Limited Produits de soin pour les plaies contenant de la keratine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999026570A1 (fr) * 1997-11-26 1999-06-03 Keraplast Technologies, Ltd. Technique de reticulation de film, de feuilles et de materiau en vrac a base de keratine
WO2003018673A1 (fr) * 2001-08-31 2003-03-06 Keratec Limited Production de materiaux biopolymeres sous forme de films, de fibres, de mousses ou d'adhesifs, a partir de derives de keratine s-sulfonee
WO2003103737A1 (fr) * 2002-06-10 2003-12-18 Wool Research Organisaton Of New Zealand (Inc) Materiaux orthopediques derives de la keratine
WO2005058380A1 (fr) * 2003-12-19 2005-06-30 Keratec Limited Produits de soin pour les plaies contenant de la keratine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9045600B2 (en) 2009-05-13 2015-06-02 Keraplast Technologies, Ltd. Biopolymer materials
US11505587B2 (en) * 2013-01-18 2022-11-22 Nanyang Technological University Method of preparing a keratin-based biomaterial and keratin-based biomaterial formed thereof

Also Published As

Publication number Publication date
CA2665253A1 (fr) 2008-04-10
AU2007304585A1 (en) 2008-04-10
EP2079787A1 (fr) 2009-07-22

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