WO2008011755A1 - Female sanitary article and its manufacturing method - Google Patents

Female sanitary article and its manufacturing method Download PDF

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Publication number
WO2008011755A1
WO2008011755A1 PCT/CN2006/001760 CN2006001760W WO2008011755A1 WO 2008011755 A1 WO2008011755 A1 WO 2008011755A1 CN 2006001760 W CN2006001760 W CN 2006001760W WO 2008011755 A1 WO2008011755 A1 WO 2008011755A1
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WO
WIPO (PCT)
Prior art keywords
liquid
layer
sanitary
permeable surface
surface layer
Prior art date
Application number
PCT/CN2006/001760
Other languages
French (fr)
Chinese (zh)
Inventor
Yonghong Zhu
Biao Dai
Original Assignee
Kasly Holding Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kasly Holding Company Limited filed Critical Kasly Holding Company Limited
Priority to PCT/CN2006/001760 priority Critical patent/WO2008011755A1/en
Priority to TW095126741A priority patent/TW200806268A/en
Priority to MYPI20064108A priority patent/MY163529A/en
Publication of WO2008011755A1 publication Critical patent/WO2008011755A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/15577Apparatus or processes for manufacturing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/51Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators characterised by the outer layers
    • A61F13/511Topsheet, i.e. the permeable cover or layer facing the skin
    • A61F13/513Topsheet, i.e. the permeable cover or layer facing the skin characterised by its function or properties, e.g. stretchability, breathability, rewet, visual effect; having areas of different permeability
    • A61F13/51305Topsheet, i.e. the permeable cover or layer facing the skin characterised by its function or properties, e.g. stretchability, breathability, rewet, visual effect; having areas of different permeability having areas of different permeability
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • A61L2300/608Coatings having two or more layers

Definitions

  • the present invention relates to an absorbent pad and a method of preparing the same, and more particularly to an externally applied sanitary napkin and sanitary pad and a method of preparing the same. Background technique
  • Sanitary napkins and sanitary pads are similar in structure and consist of a liquid permeable surface layer, a liquid absorbing layer and a liquid impervious adhesive layer.
  • Sanitary napkins are used during women's travel. When women have menstrual cramps, their body resistance is poor, and they are prone to infection. In particular, the natural defense effect of inhibiting bacterial growth is weakened by the slight opening of the cervix, the endometrial exfoliation, and the reduction of vaginal acidity. Invasion of pathogenic bacteria can easily cause inflammation or infection of the genitourinary system. In addition, some women cannot replace sanitary napkins in time due to various reasons. The localized menstrual blood has greatly improved the humidity and poor ventilation and ventilation, which is more beneficial to the reproduction of bacteria and enhances the frequency of various gynecological diseases.
  • a feminine hygiene product which comprises a liquid permeable surface layer and is transparent a liquid absorbing layer below the liquid surface layer and a liquid-impermeable adhesive layer under the liquid absorbing layer, characterized in that the outer surface of the liquid permeable surface layer comprises borneol
  • a method of preparing a feminine hygiene product comprising the steps of: preparing a liquid absorbing layer of a sanitary article; bonding the liquid absorbing layer of the sanitary article to the liquid permeable surface layer; and bonding to the liquid absorbing layer of the sanitary article On the outer surface of the liquid permeable surface layer, a liquid medicine composed of borneol and alcohol is applied; and the other side of the liquid absorbing layer of the sanitary article is adhered to the liquid-impermeable adhesive layer.
  • the outer surface of the liquid-permeable surface layer of the hygienic article of the present invention is only applied with a liquid mixture of alcohol and borneol, the alcohol itself has a bactericidal and bacteriostatic action, and after volatilization, only the remaining water-repellent ingredients are left in the sanitary article.
  • the borneol has the functions of sterilization, bacteriostasis, anti-inflammatory, etc., so that the sanitary article of the invention can prevent, inhibit and treat various gynecological diseases.
  • the product of the present invention includes only one drug of borneol, the pressure on the natural environment caused by the abandonment after use is relatively small.
  • the content of the borneol in the feminine hygiene product of the present invention is further preferably such that, in the case of ensuring the beneficial effects of the borneol, the content of the borneol is maintained as low as possible, thereby The pressure on the environment of the inventive product is further reduced after use. In view of the amount of such products, the products of the present invention have great significance in environmental protection.
  • the sanitary article of the present invention Since the water sheet is used as a medicinal ingredient, the sanitary article of the present invention has a cool and comfortable feeling when applied, and is suitable for use under specific climatic conditions.
  • the inventors have unexpectedly found that the hygienic article of the present invention is less susceptible to allergy due to the use of borneol as a medicinal ingredient.
  • the feminine hygiene product in the present invention may be a variety of sanitary napkins and sanitary pads, and the sanitary napkins may be classified into daily sanitary napkins and night hygiene according to different requirements of the user during the day and night. towel.
  • the feminine hygiene product of the present invention comprises a liquid permeable surface layer, a liquid absorbing layer located below the liquid permeable surface layer, and a liquid-impermeable adhesive layer under the liquid absorbing layer, wherein the liquid permeable surface outer surface comprises There are water tablets.
  • the liquid permeable surface is intended to be in direct contact with the human body, to receive body fluids, by a unidirectionally permeable material that has a fast absorption rate and ability, is capable of keeping the surface dry, and is not capable of reversing extravasation of body fluids (eg, menstrual blood). production.
  • the liquid absorbing layer is made of a polymer water absorbing material, and is capable of absorbing a large amount of body fluid, and absorbing the body fluid therein.
  • the liquid-impermeable adhesive layer is made of a material that prevents liquid penetration, which This can prevent leakage of body fluids. Further, a release paper may be adhered to the bottom of the liquid-impermeable adhesive layer as needed.
  • the specific content may vary depending on the purpose of use and the use of sanitary napkins and sanitary pads.
  • sanitary napkins are used during menstruation, and sanitary pads are used for a few days before or after menstruation or when there are more secretions during menstruation, so the sanitary napkins are required for sterilization and bacteriostatic purposes.
  • the amount of ice tablets such as anti-inflammatory is more.
  • the amount of borneol applied from the outer surface of the liquid permeable surface of the sanitary napkin and the sanitary pad, including in the sanitary napkin and the sanitary pad can each vary within a range. . 00300g/p or the diaper of the liquid permeable outer surface of the sanitary pad comprising the borneol of the sanitary napkin.
  • the amount is about 0.001 01g/p - about
  • the sanitary napkin or the sanitary pad can achieve the object of the present invention, can have a sterilization and anti-inflammatory effect, and can prevent allergy.
  • the outer surface of the liquid-permeable surface layer of the sanitary napkin comprises a water-sheet amount of about 0.0000 gg/p to about 0.000400 g/p or the outer surface of the liquid-permeable surface layer of the sanitary pad comprises about borneol.
  • 0. 00116g / p - about 0. 00140g / p sanitary napkins or sanitary pads have better sterilization and anti-inflammatory effects, and can prevent allergies.
  • the sanitary napkin or sanitary pad has the best sterilization and anti-inflammatory effects, and can also prevent allergies.
  • the borneol included in the outer surface of the liquid permeable surface layer is preferably distributed on the surface layer of the outer surface of the liquid permeable surface layer, and is evenly distributed.
  • it is critical that the total content of borneol on the outer surface of the liquid permeable surface layer.
  • the amount of the borneol applied in the sanitary napkin or the sanitary pad is less than the respective minimum amount specified in the foregoing invention, the effects of sterilization, bacteriostasis, anti-inflammatory, etc. are relatively poor, and the invention is not obtained. the goal of.
  • the amount of the borneol applied in the sanitary napkin or the sanitary pad is greater than the respective maximum amounts specified in the foregoing invention, although the object of the present invention can be attained, the effects of sterilization, bacteriostatic, anti-inflammatory, etc. are increased. Micro, so this will cause waste of borneol drugs, while also adding some pressure to environmental protection, it is not desirable.
  • the method of preparing the feminine hygiene product of the present invention is described in detail below.
  • a polymer material having a water absorbing property such as a polymer composite paper or a dust-free paper, is formed into a liquid absorbing layer having a desired shape, for example, a strip shape.
  • the liquid absorbing layer has a strong adsorption property and can absorb body fluids or other excretions.
  • the liquid permeable surface layer is preferably made of a material that has unidirectional penetration and is not capable of reverse osmosis.
  • liquid medicine composed of borneol and a pharmaceutically acceptable solvent (e.g., alcohol)
  • a pharmaceutically acceptable solvent e.g., alcohol
  • the concentration of the liquid medicine composed of borneol and alcohol may also vary within a certain range, as long as the amount of borneol contained in the sanitary article applied from the outer surface of the liquid permeable surface layer of the sanitary article can reach the present invention.
  • the purpose of sterilization, anti-inflammatory, and the amount of the liquid is relatively easy to dry the sanitary article.
  • the concentration of the liquid medicine may be from about 4:100 g/ml to about 6:100 g/ml, and the amount of the liquid medicine applied to each sanitary article at this time can satisfy the above requirements, and can be ensured to be applied to sanitary articles.
  • the concentration of the drug solution is in the range of about 4. 5: 100 g/ml to about 5. 5: 100 g/ml. More preferably, the concentration of the drug solution is about 5: 100 g/ml.
  • Administration herein includes all possible methods for uniformly applying the mixed solution to the sanitary article from the outer surface of the liquid permeable topsheet of the sanitary article, for example, spraying, brushing, and the like.
  • the liquid medicine composed of borneol and alcohol is applied to the outer surface of the liquid permeable surface layer, the liquid medicine is substantially infiltrated, and the sanitary product can be optionally dried.
  • an adhesive is applied to the other side of the liquid absorbing layer or to one side of the liquid-impermeable adhesive layer, and the liquid-impermeable adhesive layer is adhered to the other side of the liquid absorbing layer.
  • Example 1 Preparation of sanitary napkin
  • the polymeric paper is transferred to a tissue wrapping device, which is wrapped with a toilet paper into a sanitary napkin tampon which acts as a liquid absorbing layer in the sanitary napkin.
  • the tampon is then cut, and the glue is applied to the upper side or a side of a liquid permeable surface cloth using a glue applicator, and the two are bonded together.
  • a liquid medicine composed of borneol and alcohol on the outer surface layer of the surface cloth which has been bonded to the sliver, and enter the diversion tank device so that the sprayed liquid medicine is hooked in the effective area. penetration.
  • the borneol was placed in a 70% alcohol solution and prepared with a 15 ml solution at a concentration of 4:100 (g/ml). The 15 ml of the drug solution was applied to 200 sheets of the sanitary napkin or the sanitary napkin.
  • Example 1 a sanitary napkin tampon was prepared and bonded to a liquid permeable surface cloth.
  • a liquid chemical composed of a water sheet and alcohol is sprayed on the outer surface of the surface cloth which has been bonded to the sliver, and is introduced into the dredging device to uniformly permeate the sprayed liquid in the effective area.
  • the borneol was placed in an alcohol having a concentration of 72%, and a 16 ml liquid having a concentration of 6:100 (g/ml) was prepared.
  • the 16 ml of the drug solution was applied to 200 sheets of the sanitary napkin or the sanitary napkin.
  • the sanitary napkin coated with the medical liquid is dried using a drying device.
  • Example 1 a sanitary napkin tampon was prepared and bonded to a liquid permeable surface cloth.
  • the liquid surface composed of the water piece and the alcohol is sprayed on the outer surface layer of the surface cloth which has been bonded to the sliver, and enters the diversion tank device so that the sprayed liquid medicine is in the effective area. Penetrate evenly.
  • the water piece was placed in an alcohol having a concentration of 75%, and a 30 ml liquid medicine having a concentration of 5:100 (g/ml) was prepared. The 30 ml of the drug solution was applied to 400 sheets of the sanitary napkin or night sanitary napkin.
  • the sanitary napkin coated with the medical liquid is dried using a drying device.
  • a casting film made of a liquid-impermeable material is attached to the other side of the sliver.
  • a clean paper is prepared, which has a certain water absorption property.
  • a glue sprayer is used to spray glue on one side of the dust-free paper or on one side of a liquid-permeable surface cloth, and to bond the two together.
  • Example 4 a dust-free paper was prepared and bonded to a liquid-permeable surface cloth.
  • the liquid material composed of the water sheet and the alcohol is sprayed on the outer surface layer of the surface cloth which has been bonded to the dust-free paper, and the liquid medicine is uniformly permeated in the effective area.
  • the water piece was placed in an alcohol having a concentration of 72%, and a 21 ml solution having a concentration of 6:100 (g/ml) was prepared.
  • the 21 ml of the drug solution was applied to 800 pieces of the sanitary pad.
  • the sanitary pad that has been sprayed with the drug solution is dried by a drying device.
  • Example 6 Preparation of a sanitary pad
  • Example 4 a dust-free paper was prepared and adhered to a liquid-permeable surface cloth. put them together.
  • the liquid surface composed of the ice sheet and the alcohol is sprayed on the outer surface layer of the surface cloth which has been bonded to the dust-free paper, and the liquid medicine is infiltrated in the effective area.
  • the water piece was placed in an alcohol having a concentration of 75%, and a 15 ml liquid solution having a concentration of 5:100 (g/ml) was prepared.
  • the 15 ml of the drug solution was applied to 600 pieces of the sanitary pad.
  • the sanitary pad that has been sprayed with the drug solution is dried by a drying device.
  • Example 4 the dust-free paper was bonded to the liquid-impermeable cast film, and subjected to full-temperature heat sealing and setting.
  • Skin allergy test experimental animal, guinea pig. RESULTS: Animal skin test area did not show erythema and edema 6 to 12 hours after acute administration, and the skin sensitization rate was zero.
  • Vaginal stimulation test experimental animals, rabbits. RESULTS: There was no abnormality such as congestion and edema in the vaginal wall of rabbits. There was no difference between the two groups and the blank control group, indicating that the borneol had no obvious stimulating effect on the vagina.
  • Analgesic experiment Experimental animals, Kunming mice. RESULTS: Compared with the blank control group, low doses of borneol significantly increased the pain threshold in mice induced by thermal stimulation. It shows that borneol has an analgesic effect.
  • Antipruritic test experimental animals, guinea pigs. RESULTS: The borneol dose group significantly increased histamine-induced itch response in guinea pigs. Description of borneol on guinea pig induced by histamine phosphate Itching has a certain antipruritic effect.
  • Antibacterial test In vitro antibacterial experiment was carried out with borneol.
  • the water tablet has antibacterial effect at a lower concentration, and has a bactericidal effect at a high concentration. The longer the contact time, the stronger the antibacterial effect.
  • the test proved that the borneol has obvious bactericidal action against Staphylococcus aureus, Streptococcus hemolyticus, Streptococcus mutans, Streptococcus pneumoniae and Escherichia coli.
  • Case selection Patients with pruritus itching, redness and vaginal secretion, as well as patients with vaginal inflammation and vaginitis.
  • the invention mainly observes clinical curative effect on patients with irregular menstruation, under-sex, and pruritus.
  • the selected patients were mainly distributed in Xi'an and Nanjing, where there were significant differences in all aspects of the climate. Of these, 41 out of a total of 189 patients had allergies due to various reasons for using sanitary napkins or sanitary pads.
  • Hygiene articles Prepared according to the examples.
  • the sanitary article of the present invention is clinically summarized for patients with irregular menstruation, under-belt, and itching (using the sanitary napkin prepared in Example 1 and the sanitary pad prepared in Example 4)
  • the user After using the sanitary article of the present invention, the user has a no-allergy comparison table (using the sanitary napkin prepared in Example 3 and the sanitary pad prepared in Example 6): Use the product with or without sanitary napkins or sanitary care. The number of people in the area of production is not allergic.
  • the hygienic article of the invention has good prevention, inhibition and treatment for various vaginitis, pelvic inflammatory disease and the resulting symptoms of genital itching and redness. effect.
  • this feminine hygiene product is suitable for both the southern and northern populations of China, and has a wide range of applications and is not easy to cause allergies.
  • the feminine hygiene product of the present invention is reduced in the amount of the traditional Chinese medicine contained in the commercially available pharmaceutical similar product, the damage caused by the drug loss on the environment is greatly reduced.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Manufacturing & Machinery (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A kind of female sanitary article which comprises a liquid permeable surface layer, a liquid absorptive layer under the liquid permeable surface layer and a liquid impermeable adhesive layer under the liquid absorptive layer, wherein the exterior surface of the liquid permeable surface layer contains borneol. And a method for manufacturing the female sanitary article, wherein the medicinal solution mixed only by borneol and alcohol is sprayed onto the exterior surface of the liquid permeable surface layer.

Description

女性卫生用品及其制备方法 发曰月领域  Feminine hygiene products and preparation method thereof
本发明涉及一种吸收垫及其制备方法, 更具体而言, 涉及一种体 外贴敷的卫生巾和卫生护垫及其制备方法。 背景技术  The present invention relates to an absorbent pad and a method of preparing the same, and more particularly to an externally applied sanitary napkin and sanitary pad and a method of preparing the same. Background technique
卫生巾及卫生护垫结构相似, 都是由透液性表层、 吸液层和不透 液性粘附层组成。  Sanitary napkins and sanitary pads are similar in structure and consist of a liquid permeable surface layer, a liquid absorbing layer and a liquid impervious adhesive layer.
卫生巾供女性行经期间使用。女性月经来潮时,全身抵抗力较差, 易于感染疾病, 特别是由于子宫颈口微张、 子宫内膜剥落留有创面、 阴道酸度降低而抑制细菌生长的自然防御作用有所削弱, 因此, 一旦 致病菌入侵, 极易引起泌尿生殖系统炎症或感染。 加之部分女性由于 各种原因而不能适时更换卫生巾, 局部积存的经血使湿度大大提高、 通风透气性变差, 这对细菌繁衍更有利, 提升了各种妇科疾病发病的 频率。  Sanitary napkins are used during women's travel. When women have menstrual cramps, their body resistance is poor, and they are prone to infection. In particular, the natural defense effect of inhibiting bacterial growth is weakened by the slight opening of the cervix, the endometrial exfoliation, and the reduction of vaginal acidity. Invasion of pathogenic bacteria can easily cause inflammation or infection of the genitourinary system. In addition, some women cannot replace sanitary napkins in time due to various reasons. The localized menstrual blood has greatly improved the humidity and poor ventilation and ventilation, which is more beneficial to the reproduction of bacteria and enhances the frequency of various gynecological diseases.
另外, 很多女性在经血少或分泌物较多时使用卫生护垫, 由于卫 生护垫结构与卫生巾相似, 所以同样存在有利于细菌繁衍、 可能导致 各种妇科疾病的缺点。  In addition, many women use sanitary pads when there is less menstrual blood or more secretions. Because the sanitary pad structure is similar to sanitary napkins, there are also disadvantages that are beneficial to bacterial reproduction and may lead to various gynecological diseases.
目前市场上出现的妇女卫生用品中, 有些用多种中草药物等施用 于卫生用品表面或将多种中草药物颗粒包于卫生用品内部结构中, 这 样能够起到杀菌、 抑菌、 通窍、 镇痛、 去除炎症及散播香味等作用, 从而达到预防多种妇科疾病以及去除经血异味的目的。 但是, 这些产 品大多包括多种药物, 成本偏高。 同时, 这些产品一次性使用后即抛 弃, 目前尚无回收处理的成熟技术, 仍然采取填埋的方法处理。 因此, 其中的药物如果能够减少种类和数量, 对于环境保护而言, 显然是有 意义的。 发明内容  Among the women's hygiene products currently on the market, some are applied to the surface of sanitary products with a variety of Chinese herbal medicines or a variety of Chinese herbal medicine particles are packaged in the internal structure of sanitary products, which can sterilize, inhibit bacteria, alleviate and analgesic. It removes inflammation and spreads fragrance, thus achieving the purpose of preventing various gynecological diseases and removing menstrual blood odor. However, most of these products include multiple drugs and are costly. At the same time, these products are discarded after being used once. There is no mature technology for recycling, and they are still treated by landfill. Therefore, if the drugs can reduce the types and quantities, it is obviously meaningful for environmental protection. Summary of the invention
本发明的目的在于提供一种能够杀菌、 消炎且能减少对环境污染 的女性卫生用品及其制备方法。  It is an object of the present invention to provide a feminine hygiene product which is sterilizable, anti-inflammatory and which can reduce environmental pollution and a preparation method thereof.
根据本发明, 提供一种女性卫生用品, 包括透液性表层、 位于透 液性表层下方的吸液层以及位于所述吸液层下方的不透液性粘附层, 其特征在于, 透液性表层外表面包括有冰片 According to the present invention, a feminine hygiene product is provided, which comprises a liquid permeable surface layer and is transparent a liquid absorbing layer below the liquid surface layer and a liquid-impermeable adhesive layer under the liquid absorbing layer, characterized in that the outer surface of the liquid permeable surface layer comprises borneol
根据本发明, 还提供一种制备女性卫生用品的方法, 包括如下步 骤: 制备卫生用品吸液层; 将卫生用品吸液层与透液性表层粘结; 在 已与卫生用品吸液层粘结的透液性表层外表面上, 施用由冰片与酒精 组成的药液; 将卫生用品吸液层的另一面与不透液性粘附层粘贴。  According to the present invention, there is also provided a method of preparing a feminine hygiene product comprising the steps of: preparing a liquid absorbing layer of a sanitary article; bonding the liquid absorbing layer of the sanitary article to the liquid permeable surface layer; and bonding to the liquid absorbing layer of the sanitary article On the outer surface of the liquid permeable surface layer, a liquid medicine composed of borneol and alcohol is applied; and the other side of the liquid absorbing layer of the sanitary article is adhered to the liquid-impermeable adhesive layer.
由于本发明的卫生用品的透液性表层外表面仅施用由酒精和冰片 混合而成的药液, 酒精本身具有杀菌、 抑菌的作用, 其挥发后在卫生 用品中只剩留)水片成分, 而冰片又具有杀菌、 抑菌、 消炎等作用, 因 而本发明的卫生用品能够达到预防、抑制、 治疗各种妇科疾病。 同时, 由于本发明的产品中仅包括冰片一种药物, 因而在使用其后的抛弃对 自然环境造成的压力相对较小。 在本发明的一个优选实施方案中, 本 发明的妇女卫生用品中冰片的含量进一步优选, 在确保冰片的有益效 果的情况下, 使冰片的含量尽可能维持在一个较低的水平, 从而使得 本发明的产品在使用后对环境的压力进一步减小。 考虑到此类产品的 用量, 本发明的产品在环境保护方面具有很大的意义。  Since the outer surface of the liquid-permeable surface layer of the hygienic article of the present invention is only applied with a liquid mixture of alcohol and borneol, the alcohol itself has a bactericidal and bacteriostatic action, and after volatilization, only the remaining water-repellent ingredients are left in the sanitary article. The borneol has the functions of sterilization, bacteriostasis, anti-inflammatory, etc., so that the sanitary article of the invention can prevent, inhibit and treat various gynecological diseases. Meanwhile, since the product of the present invention includes only one drug of borneol, the pressure on the natural environment caused by the abandonment after use is relatively small. In a preferred embodiment of the present invention, the content of the borneol in the feminine hygiene product of the present invention is further preferably such that, in the case of ensuring the beneficial effects of the borneol, the content of the borneol is maintained as low as possible, thereby The pressure on the environment of the inventive product is further reduced after use. In view of the amount of such products, the products of the present invention have great significance in environmental protection.
由于采用水片作为药用成分, 本发明的卫生用品在贴敷使用时还 会有清凉舒适的感觉, 适于在特定的气候条件下使用。  Since the water sheet is used as a medicinal ingredient, the sanitary article of the present invention has a cool and comfortable feeling when applied, and is suitable for use under specific climatic conditions.
另外, 本发明人还意外地发现, 由于采用冰片作为药用成分, 本 发明的卫生用品不易致人过敏。 具体实施方式  Further, the inventors have unexpectedly found that the hygienic article of the present invention is less susceptible to allergy due to the use of borneol as a medicinal ingredient. detailed description
本发明中的女性卫生用品可以是通常所说的各种卫生巾及卫生护 垫, 而卫生巾根据使用者在白天与夜晚的不同使用要求等, 又可以分 为日用卫生巾和夜用卫生巾。  The feminine hygiene product in the present invention may be a variety of sanitary napkins and sanitary pads, and the sanitary napkins may be classified into daily sanitary napkins and night hygiene according to different requirements of the user during the day and night. towel.
本发明的女性卫生用品包括透液性表层、 位于透液性表层下方的 吸液层以及位于所述吸液层下方的不透液性粘附层, 其特征在于, 透 液性表层外表面包括有水片。 如常规的同类产品一样, 所述透液性表 面拟与人体直接接触、 接受体液, 由吸收速率及能力快、 能够保持表 面干爽、 且不能反向外渗体液(例如经血) 的单向渗透材料制成。 所 述吸液层是由高分子吸水材料制成, 能够大量吸收体液, 吸收后体液 藏于其内部。 所述不透液性粘附层是由阻止液体渗透的材料制成, 这 样可以防止体液外漏。 另外, 还可以根据需要, 任选在不透液性粘附 层的底部粘有离型纸。 The feminine hygiene product of the present invention comprises a liquid permeable surface layer, a liquid absorbing layer located below the liquid permeable surface layer, and a liquid-impermeable adhesive layer under the liquid absorbing layer, wherein the liquid permeable surface outer surface comprises There are water tablets. As with conventional products of the same type, the liquid permeable surface is intended to be in direct contact with the human body, to receive body fluids, by a unidirectionally permeable material that has a fast absorption rate and ability, is capable of keeping the surface dry, and is not capable of reversing extravasation of body fluids (eg, menstrual blood). production. The liquid absorbing layer is made of a polymer water absorbing material, and is capable of absorbing a large amount of body fluid, and absorbing the body fluid therein. The liquid-impermeable adhesive layer is made of a material that prevents liquid penetration, which This can prevent leakage of body fluids. Further, a release paper may be adhered to the bottom of the liquid-impermeable adhesive layer as needed.
本发明的透液性表层外表面包括的水片含量通常为 0. 0010g/p (克 /片, 下同) -约 0. 0050g/p , 优选为 0. 00115g/p -约 0. 0040g/p , 更优选为 0. 00125g/p -约 0. 00375g/p , 具体含量可因卫生巾和卫生护 垫的使用目的及使用情况不同而不同。 一般而言, 卫生巾使用于女性 行经期间, 而卫生护垫使用于经期前后几天或非经期分泌物较多时, 故相对于卫生护垫而言, 卫生巾上需要的用于杀菌、 抑菌、 消炎等的 冰片量要多。 且在保证能达到本发明目的的情况下, 从卫生巾和卫生 护垫的透液性表层外表面上施用的、 包括在卫生巾和卫生护垫内的冰 片量都可以各自在一个范围内变化。 经实践证明, 当所述卫生巾的透 液性表层外表面包括的冰片量为约 0. 00300g/p-约 0. 00480g/p或所述 卫生护垫的透液性表层外表面包括的冰片量为约 0. 001 01g/p -约  0015g/p - about 0. 0040g / / 0. 0010g / p - 0. 0040g / p - 0. 0040g / p - 0. 0040g / p. p, more preferably 0. 00125g / p - about 0. 00375g / p, the specific content may vary depending on the purpose of use and the use of sanitary napkins and sanitary pads. In general, sanitary napkins are used during menstruation, and sanitary pads are used for a few days before or after menstruation or when there are more secretions during menstruation, so the sanitary napkins are required for sterilization and bacteriostatic purposes. And the amount of ice tablets such as anti-inflammatory is more. And, in the case of ensuring that the object of the present invention is achieved, the amount of borneol applied from the outer surface of the liquid permeable surface of the sanitary napkin and the sanitary pad, including in the sanitary napkin and the sanitary pad, can each vary within a range. . 00300g/p or the diaper of the liquid permeable outer surface of the sanitary pad comprising the borneol of the sanitary napkin. The amount is about 0.001 01g/p - about
0. 00157g/p时, 所述卫生巾或卫生护垫可以达到本发明的目的, 能够 起到杀菌、 消炎的效果, 并可以防止过敏。 当所述卫生巾的透液性表 层外表面包括的水片量为约 0. 00350g/p-约 0. 00400g/p或所述卫生护 垫的透液性表层外表面包括的冰片量为约 0. 00116g/p -约 0. 00140g/p 时, 卫生巾或卫生护垫的杀菌、 消炎效果较好, 可以防止过敏。 当所 述卫生巾的透液性表层外表面包括的冰片量为约 0. 00375g/p或所述 卫生护垫的透液性表层外表面包括的冰片量为约 0. 00125g/p时,所述 卫生巾或卫生护垫的杀菌、 消炎效果最好, 同时也可以防止过敏。 At 0. 00157 g/p, the sanitary napkin or the sanitary pad can achieve the object of the present invention, can have a sterilization and anti-inflammatory effect, and can prevent allergy. When the outer surface of the liquid-permeable surface layer of the sanitary napkin comprises a water-sheet amount of about 0.0000 gg/p to about 0.000400 g/p or the outer surface of the liquid-permeable surface layer of the sanitary pad comprises about borneol. 0. 00116g / p - about 0. 00140g / p, sanitary napkins or sanitary pads have better sterilization and anti-inflammatory effects, and can prevent allergies. 00125g/p, when the amount of borneol of the outer surface of the liquid-repellent surface of the sanitary napkin is about 0. 00125g / p, The sanitary napkin or sanitary pad has the best sterilization and anti-inflammatory effects, and can also prevent allergies.
本发明妇女卫生用品中, 透液性表层外表面所包括的冰片优选分 布在所述透液性表层外表面的表层上, 并且为平均分布。 但是, 必须 指出, 在本发明中, 关键的是冰片在所述透液性表层外表面上的总含 量。  In the feminine hygiene product of the present invention, the borneol included in the outer surface of the liquid permeable surface layer is preferably distributed on the surface layer of the outer surface of the liquid permeable surface layer, and is evenly distributed. However, it must be noted that in the present invention, it is critical that the total content of borneol on the outer surface of the liquid permeable surface layer.
需要说明的是, 当在所述卫生巾或卫生护垫中施用的冰片的量不 足本发明前述规定的各自最小用量时, 杀菌、 抑菌以及消炎等的效果 相对较差, 达不到本发明的目的。 相反, 当在所述卫生巾或卫生护垫 中施用的冰片的量大于本发明前述规定的各自最大用量时, 虽然能达 到本发明的目的, 但由于杀菌、 抑菌以及消炎等的效果增加甚微, 因 而这样会造成冰片药物浪费, 同时还给环境保护增加一定压力, 因此 不可取。 下面详细介绍制备本发明的女性卫生用品的方法。 It should be noted that when the amount of the borneol applied in the sanitary napkin or the sanitary pad is less than the respective minimum amount specified in the foregoing invention, the effects of sterilization, bacteriostasis, anti-inflammatory, etc. are relatively poor, and the invention is not obtained. the goal of. On the contrary, when the amount of the borneol applied in the sanitary napkin or the sanitary pad is greater than the respective maximum amounts specified in the foregoing invention, although the object of the present invention can be attained, the effects of sterilization, bacteriostatic, anti-inflammatory, etc. are increased. Micro, so this will cause waste of borneol drugs, while also adding some pressure to environmental protection, it is not desirable. The method of preparing the feminine hygiene product of the present invention is described in detail below.
首先, 将具有吸水特性的高分子材料, 例如高分子复合纸、 无尘 纸等, 制作成所需形状的吸液层, 例如长条状。 该吸液层具有很强的 吸附特性, 可以吸收体液或其它排泄物。  First, a polymer material having a water absorbing property, such as a polymer composite paper or a dust-free paper, is formed into a liquid absorbing layer having a desired shape, for example, a strip shape. The liquid absorbing layer has a strong adsorption property and can absorb body fluids or other excretions.
随后, 在该吸液层的一面或一透液性表层的一面施用粘合剂, 并 将该吸液层和透液性表层粘结, 使二者结合在一起。 该透液性表层优 选是由具有单向渗透、 且不能反向渗透的材料制得。 这样可以在由前 述制得的吸液层将体液吸收后, 体液不会再反渗到该透液性表层的外 表面, 从而可保持与人体接触的该透液性表层的外表面干爽。  Subsequently, an adhesive is applied to one side of the liquid absorbing layer or one side of a liquid permeable surface layer, and the liquid absorbing layer and the liquid permeable surface layer are bonded to bond the two together. The liquid permeable surface layer is preferably made of a material that has unidirectional penetration and is not capable of reverse osmosis. Thus, after the body fluid is absorbed by the liquid absorbing layer prepared as described above, the body fluid does not re-infiltrate to the outer surface of the liquid permeable surface layer, so that the outer surface of the liquid permeable surface layer which is in contact with the human body can be kept dry.
此时, 就可以在透液性表层外表面上施用已配备好的由冰片与可 药用溶剂 (例如酒精)组成的药液。 如果采用酒精, 则其浓度可以为 At this time, it is possible to apply a liquid medicine composed of borneol and a pharmaceutically acceptable solvent (e.g., alcohol) to the outer surface of the liquid permeable surface layer. If alcohol is used, its concentration can be
70 % - 75 %。 而且, 随着酒精浓度的增加, 杀菌效果会越来越好, 当 所述酒精浓度为 75 %时, 效果最好。 所述由冰片与酒精组成的药液的 浓度也可以在一定范围内变化, 只要从卫生用品的透液性表层的外表 面上施用的、 包含在卫生用品中的冰片的量可以达到本发明的杀菌、 消炎的目的、 且该药液量又比较容易使得所述卫生用品干燥即可。 例 如,所述药液的浓度可以为约 4: 100g/ml -约 6: 100g/ml ,此时施用于 每片卫生用品上的药液的量可以满足上述要求, 并能保证施于卫生用 品的透液性表层的外表面的冰片量。 优选地, 所述药液的浓度为约 4. 5: 100 g/ml -约 5. 5: 100g/ml的范围内。 更优选地, 所述药液的浓 度为约 5: 100 g/ml。 这里的 "施用" 包括可以将该混合药液均匀由卫 生用品的透液性表层的外表面上施用到卫生用品的所有可行方法, 例 如, 喷涂、 刷洒等。 70% - 75%. Moreover, as the concentration of alcohol increases, the bactericidal effect will be better and better, and when the alcohol concentration is 75 %, the effect is best. The concentration of the liquid medicine composed of borneol and alcohol may also vary within a certain range, as long as the amount of borneol contained in the sanitary article applied from the outer surface of the liquid permeable surface layer of the sanitary article can reach the present invention. The purpose of sterilization, anti-inflammatory, and the amount of the liquid is relatively easy to dry the sanitary article. For example, the concentration of the liquid medicine may be from about 4:100 g/ml to about 6:100 g/ml, and the amount of the liquid medicine applied to each sanitary article at this time can satisfy the above requirements, and can be ensured to be applied to sanitary articles. The amount of borneol on the outer surface of the liquid permeable surface layer. Preferably, the concentration of the drug solution is in the range of about 4. 5: 100 g/ml to about 5. 5: 100 g/ml. More preferably, the concentration of the drug solution is about 5: 100 g/ml. "Administration" herein includes all possible methods for uniformly applying the mixed solution to the sanitary article from the outer surface of the liquid permeable topsheet of the sanitary article, for example, spraying, brushing, and the like.
在透液性表层的外表面上施用由冰片与酒精组成的药液之后, 待 药液基本渗透均勾, 还可以任选地对卫生用品进行干燥。 最后, 在吸 液层的另一面或一不透液性粘附层的一面上施用粘合剂, 并将该不透 液性粘附层粘贴在吸液层的该另一面上。 这样, 就制得了本发明中的 卫生用品。  After the liquid medicine composed of borneol and alcohol is applied to the outer surface of the liquid permeable surface layer, the liquid medicine is substantially infiltrated, and the sanitary product can be optionally dried. Finally, an adhesive is applied to the other side of the liquid absorbing layer or to one side of the liquid-impermeable adhesive layer, and the liquid-impermeable adhesive layer is adhered to the other side of the liquid absorbing layer. Thus, the sanitary article of the present invention is obtained.
当然, 也可以任选地在所述卫生用品的不透液性粘附层上粘贴一 离型纸。 这样在使用时, 使用者可以撕掉离型纸, 就将带有粘性的卫 生用品粘贴在衣物上。  Of course, it is also possible to affix a release paper to the liquid-impermeable adhesive layer of the sanitary article. Thus, when in use, the user can peel off the release paper and attach the sticky sanitary article to the garment.
通过以下具体的实施例对本发明作更详细的说明。 实施例 1 : 卫生巾的制备 The invention is illustrated in more detail by the following specific examples. Example 1: Preparation of sanitary napkin
首先, 将高分子复令纸传送到覆卫生纸包裹装置, 用卫生纸将其 包裹成卫生巾棉条, 该棉条在卫生巾中充当吸液层。  First, the polymeric paper is transferred to a tissue wrapping device, which is wrapped with a toilet paper into a sanitary napkin tampon which acts as a liquid absorbing layer in the sanitary napkin.
随后切割棉条, 使用喷胶装置在其上一面或在一透液性表面布的 一面上喷涂胶水, 并使得两者粘合在一起。  The tampon is then cut, and the glue is applied to the upper side or a side of a liquid permeable surface cloth using a glue applicator, and the two are bonded together.
此时, 就可以在已与棉条粘结的表面布外表层上喷涂已配备好的 由冰片与酒精組成的药液, 并进入导流槽装置使喷涂的药液在有效区 域内均勾地渗透。 将冰片放入浓度为 70%的酒精内, 配备制得浓度为 4: 100 ( g/ml )的 15ml药液。 该 15ml药液施用于 200片所述日用卫生 巾或夜用卫生巾上。  At this time, it is possible to spray a liquid medicine composed of borneol and alcohol on the outer surface layer of the surface cloth which has been bonded to the sliver, and enter the diversion tank device so that the sprayed liquid medicine is hooked in the effective area. penetration. The borneol was placed in a 70% alcohol solution and prepared with a 15 ml solution at a concentration of 4:100 (g/ml). The 15 ml of the drug solution was applied to 200 sheets of the sanitary napkin or the sanitary napkin.
待药液在卫生巾表层基本渗透均勾后,在棉条另一面上喷涂胶水, 接着将不透液材料制成的流延膜粘贴在棉条的该另一面上。 至此, 就 得到了本发明的产品。 实施例 2: 卫生巾的制备  After the liquid medicine is substantially infiltrated on the surface of the sanitary napkin, the glue is sprayed on the other side of the sliver, and then a cast film made of a liquid-impermeable material is attached to the other side of the sliver. So far, the product of the present invention has been obtained. Example 2: Preparation of sanitary napkin
参照实施例 1 , 制备好卫生巾棉条并将其与一透液性表面布粘合 在一起。  Referring to Example 1, a sanitary napkin tampon was prepared and bonded to a liquid permeable surface cloth.
随后, 在已与棉条粘结的表面布外表层上喷涂已配备好的由水片 与酒精组成的药液, 并进入导流槽装置使喷涂的药液在有效区域内均 匀地渗透。 本实施例中, 将冰片放入浓度为 72%的酒精内, 配备制得 浓度为 6: 100 ( g/ml )的 16ml药液。 该 16ml药液施用于 200片所述 日用卫生巾或夜用卫生巾上。  Subsequently, a liquid chemical composed of a water sheet and alcohol is sprayed on the outer surface of the surface cloth which has been bonded to the sliver, and is introduced into the dredging device to uniformly permeate the sprayed liquid in the effective area. In the present embodiment, the borneol was placed in an alcohol having a concentration of 72%, and a 16 ml liquid having a concentration of 6:100 (g/ml) was prepared. The 16 ml of the drug solution was applied to 200 sheets of the sanitary napkin or the sanitary napkin.
接着, 使用干燥装置对已涂有药液的所述卫生巾进行干燥。  Next, the sanitary napkin coated with the medical liquid is dried using a drying device.
随后, 再次参照实施例 1 , 待药液在卫生巾表层基本渗透均匀后, 将不透液材料制成的流延膜粘贴在棉条的该另一面上。 实施例 3: 卫生巾的制备  Subsequently, referring again to the embodiment 1, after the liquid medicine is substantially uniformly permeated on the surface layer of the sanitary napkin, a casting film made of a liquid-impermeable material is attached to the other side of the sliver. Example 3: Preparation of sanitary napkin
参照实施例 1 , 制备好卫生巾棉条并将其与一透液性表面布粘合 在一起。  Referring to Example 1, a sanitary napkin tampon was prepared and bonded to a liquid permeable surface cloth.
随后, 在已与棉条粘结的表面布外表层上喷涂已配备好的由水片 与酒精组成的药液, 并进入导流槽装置使喷涂的药液在有效区域内均 匀地渗透。 本实施例中, 将水片放入浓度为 75%的酒精内, 配备制得 浓度为 5: 100 ( g/ml ) 的 30ml药液。 该 30ml药液施用于 400片所述 日用卫生巾或夜用卫生巾上。 Subsequently, the liquid surface composed of the water piece and the alcohol is sprayed on the outer surface layer of the surface cloth which has been bonded to the sliver, and enters the diversion tank device so that the sprayed liquid medicine is in the effective area. Penetrate evenly. In the present embodiment, the water piece was placed in an alcohol having a concentration of 75%, and a 30 ml liquid medicine having a concentration of 5:100 (g/ml) was prepared. The 30 ml of the drug solution was applied to 400 sheets of the sanitary napkin or night sanitary napkin.
接着, 使用干燥装置对已涂有药液的所述卫生巾进行干燥。  Next, the sanitary napkin coated with the medical liquid is dried using a drying device.
随后, 再次参照实施例 1 , 待药液在卫生巾表层基本渗透均匀后, 将不透液材料制成的流延膜粘贴在棉条的该另一面上。  Subsequently, referring again to the embodiment 1, after the liquid medicine is substantially uniformly permeated on the surface layer of the sanitary napkin, a casting film made of a liquid-impermeable material is attached to the other side of the sliver.
最后, 在所述不透液性流延膜的另一面上粘附离型纸。 实施例 4: 卫生护垫的制备  Finally, a release paper is adhered to the other side of the liquid-impermeable cast film. Example 4: Preparation of Sanitary Pads
首先, 准备无尘纸, 该无尘纸具有一定的吸水性。  First, a clean paper is prepared, which has a certain water absorption property.
使用喷胶装置在该无尘纸一面上或在一透液性表面布的一面上喷 涂胶水, 并使得两者粘合在一起。  A glue sprayer is used to spray glue on one side of the dust-free paper or on one side of a liquid-permeable surface cloth, and to bond the two together.
此时, 就可以在已与无尘纸粘结的表面布外表层上喷涂已配备好 的由水片与酒精组成的药液, 并使药液在有效区域内均勾地渗透。 将 水片放入浓度为 70%的酒精内, 配备制得浓度为 4: 100 ( g/ml )的 33ml 药液。 该 33ml药液施用于 1300片所述卫生护垫上。  At this time, it is possible to spray a liquid chemical composed of water and alcohol on the outer surface of the surface cloth which has been bonded to the dust-free paper, and to infiltrate the liquid in the effective area. The water piece was placed in a 70% alcohol solution and a 33 ml solution was prepared at a concentration of 4:100 (g/ml). The 33 ml of the drug solution was applied to 1,300 of the sanitary pads.
使用喷胶装置在无尘纸另一面上或者在不透液性流延膜的一面上 喷涂胶水, 并将二者粘合在一起, 进行全周热封合定型。 实施例 5 : 卫生护垫的制备  The glue is applied to the other side of the dust-free paper or to the side of the liquid-impermeable cast film, and the two are bonded together for heat sealing and setting. Example 5: Preparation of Sanitary Pads
首先, 参照实施例 4, 制备无尘纸, 并将其与一透液性表面布粘 合在一起。  First, referring to Example 4, a dust-free paper was prepared and bonded to a liquid-permeable surface cloth.
随后, 在已与无尘纸粘结的表面布外表层上喷涂已配备好的由水 片与酒精组成的药液, 并使药液在有效区域内均匀地渗透。 将水片放 入浓度为 72%的酒精内, 配备制得浓度为 6: 100 ( g/ml )的 21ml药液。 该 21ml药液施用于 800片所述卫生护垫上。  Subsequently, the liquid material composed of the water sheet and the alcohol is sprayed on the outer surface layer of the surface cloth which has been bonded to the dust-free paper, and the liquid medicine is uniformly permeated in the effective area. The water piece was placed in an alcohol having a concentration of 72%, and a 21 ml solution having a concentration of 6:100 (g/ml) was prepared. The 21 ml of the drug solution was applied to 800 pieces of the sanitary pad.
接着, 通过干燥装置对已喷涂有药液的卫生护垫进行干燥。  Next, the sanitary pad that has been sprayed with the drug solution is dried by a drying device.
随后, 再次参照实施例 4 , 将无尘纸与不透液性流延膜粘合在一 起, 进行全周热封合定型。 实施例 6: 卫生护垫的制备  Subsequently, referring again to Example 4, the dust-free paper was bonded to the liquid-impermeable cast film to perform heat sealing and setting for the entire circumference. Example 6: Preparation of a sanitary pad
首先, 参照实施例 4, 制备无尘纸, 并将其与一透液性表面布粘 合在一起。 First, referring to Example 4, a dust-free paper was prepared and adhered to a liquid-permeable surface cloth. put them together.
随后, 在已与无尘纸粘结的表面布外表层上喷涂已配备好的由冰 .片与酒精组成的药液, 并使药液在有效区域内均勾地渗透。 将水片放 入浓度为 75%的酒精内, 配备制得浓度为 5: 100 ( g/ml )的 15ml药液。 该 15ml药液施用于 600片所述卫生护垫上。  Subsequently, the liquid surface composed of the ice sheet and the alcohol is sprayed on the outer surface layer of the surface cloth which has been bonded to the dust-free paper, and the liquid medicine is infiltrated in the effective area. The water piece was placed in an alcohol having a concentration of 75%, and a 15 ml liquid solution having a concentration of 5:100 (g/ml) was prepared. The 15 ml of the drug solution was applied to 600 pieces of the sanitary pad.
接着, 通过干燥装置对已喷涂有药液的卫生护垫进行千燥。  Next, the sanitary pad that has been sprayed with the drug solution is dried by a drying device.
随后, 再次参照实施例 4, 将无尘纸与不透液性流延膜粘合在一 起, 进行全周热封合定型。  Subsequently, referring again to Example 4, the dust-free paper was bonded to the liquid-impermeable cast film, and subjected to full-temperature heat sealing and setting.
最后, 在所述不透液性流延膜的另一面上粘附离型纸。 本产品的相关实验:  Finally, a release paper is adhered to the other side of the liquid-impermeable cast film. Related experiments of this product:
一 毒性实验:  A toxicity test:
1.皮肤急性毒性实验: 实验动物, 昆明种小鼠。 结果: 动物精神、 活动、 饮食均未见任何异常反应, 未发现任何全身中毒症状, 无死亡 例, 与空白对照组一致。  1. Skin acute toxicity test: Experimental animals, Kunming mice. RESULTS: No abnormal reactions were observed in animal spirits, activities, and diet. No symptoms of systemic poisoning were found, and no deaths were observed, which was consistent with the blank control group.
2.皮肤刺激实验: 实验动物, 家兔。 结果: 皮肤刺激平均反应值 >0. 05 , 对家兔正常皮肤和损伤皮肤均无刺激性反应。  2. Skin irritation test: experimental animals, rabbits. Results: The average skin reaction value was >0.05, and there was no irritating reaction on normal skin and injured skin of rabbits.
3.皮肤过敏实验: 实验动物, 豚鼠。 结果: 动物皮肤受试区自激 发给药 6 ~ 12小时未出现红斑、 水肿, 皮肤致敏率为零。  3. Skin allergy test: experimental animal, guinea pig. RESULTS: Animal skin test area did not show erythema and edema 6 to 12 hours after acute administration, and the skin sensitization rate was zero.
4.阴道刺激实验: 实验动物, 家兔。 结果: 家兔阴道壁未见充血、 水肿等异常情况, 与空白对照组比较无差异, 说明冰片对阴道无明显 刺激性作用。 二 药效实验:  4. Vaginal stimulation test: experimental animals, rabbits. RESULTS: There was no abnormality such as congestion and edema in the vaginal wall of rabbits. There was no difference between the two groups and the blank control group, indicating that the borneol had no obvious stimulating effect on the vagina. Two pharmacodynamic experiments:
1.镇痛实验: 实验动物, 昆明种小鼠。 结果: 与空白对照组比较, 低剂量的冰片能明显提高热刺激引起小鼠的痛阈值。 说明冰片具有镇 痛作用。  1. Analgesic experiment: Experimental animals, Kunming mice. RESULTS: Compared with the blank control group, low doses of borneol significantly increased the pain threshold in mice induced by thermal stimulation. It shows that borneol has an analgesic effect.
2.抗炎症实验: 实验动物, 昆明种小鼠。 结果: 水片各剂量对二 甲苯致小鼠耳部肿胀具有显著的抑制效应, 说明水片具有一定的消除 炎症的作用。  2. Anti-inflammatory experiments: experimental animals, Kunming mice. Results: Each dose of water tablets had a significant inhibitory effect on xylene-induced ear swelling in mice, indicating that water tablets have a certain role in eliminating inflammation.
3.止痒实验: 实验动物, 豚鼠。 结果: 冰片各剂量组有显著提高 组织胺引起豚鼠致痒反应阔剂量。 说明冰片对磷酸組织胺引起的豚鼠 致痒有一定的止痒作用。 3. Antipruritic test: experimental animals, guinea pigs. RESULTS: The borneol dose group significantly increased histamine-induced itch response in guinea pigs. Description of borneol on guinea pig induced by histamine phosphate Itching has a certain antipruritic effect.
4.抗菌试验: 用冰片进行体外抗菌实验, 水片在较低浓度时有抑 菌作用, 高浓度时有杀菌作用, 接触时间越长, 抗菌效果也随之增强。 试验证明冰片对金黄色葡萄球菌、 乙型溶血性链球菌、 绿色链球菌、 肺炎链球菌、 大肠杆菌有明显的杀菌作用。 三 临床观察:  4. Antibacterial test: In vitro antibacterial experiment was carried out with borneol. The water tablet has antibacterial effect at a lower concentration, and has a bactericidal effect at a high concentration. The longer the contact time, the stronger the antibacterial effect. The test proved that the borneol has obvious bactericidal action against Staphylococcus aureus, Streptococcus hemolyticus, Streptococcus mutans, Streptococcus pneumoniae and Escherichia coli. Three clinical observations:
1.病例选择: 阴部搔痒, 赤白带下、 阴道分泌均增多的患者, 以 及带下及外阴炎症、 阴道炎患者。 本发明主要是对月经不调、 带下、 阴痒患者进行临床疗效观察。 所选患者主要分布于气候各方面都有明 显差异的西安及南京两城市。 其中, 总 189位患者中有 41位曾因使用 卫生巾或卫生护垫的各种原因而发生过过敏。  1. Case selection: Patients with pruritus itching, redness and vaginal secretion, as well as patients with vaginal inflammation and vaginitis. The invention mainly observes clinical curative effect on patients with irregular menstruation, under-sex, and pruritus. The selected patients were mainly distributed in Xi'an and Nanjing, where there were significant differences in all aspects of the climate. Of these, 41 out of a total of 189 patients had allergies due to various reasons for using sanitary napkins or sanitary pads.
2.卫生用品: 按照实施例方式制备。  2. Hygiene articles: Prepared according to the examples.
3.疗效总结:  3. Summary of curative effect:
本发明卫生用品对月经不调、 带下、 阴痒患者临床小结 (使用实 施例 1制备的卫生巾和实施例 4制备的卫生护垫)  The sanitary article of the present invention is clinically summarized for patients with irregular menstruation, under-belt, and itching (using the sanitary napkin prepared in Example 1 and the sanitary pad prepared in Example 4)
Figure imgf000009_0001
使用者使用本发明卫生用品后有、 无过敏情况对照表(使用实施 例 3制备的卫生巾和实施例 6制备的卫生护垫): 使用本产 有无卫生巾或卫生护 使用本产 地区 人数 品不过敏 垫过敏史 品过敏率
Figure imgf000009_0001
After using the sanitary article of the present invention, the user has a no-allergy comparison table (using the sanitary napkin prepared in Example 3 and the sanitary pad prepared in Example 6): Use the product with or without sanitary napkins or sanitary care. The number of people in the area of production is not allergic.
率 有 17 0 100 % 西安  Rate 17 0 100 % Xi'an
无 74 0 100 % 有 24 0 100 % 南 、  74 0 100 % has 24 0 100 % South,
无 115 0 100 % 上述实验、 临床观察以及使用效果表明: 本发明的卫生用品对各 类阴道炎、 盆腔炎以及由此引起的阴部搔痒、 赤白带下等症状具有很 好的预防、 抑制及治疗作用。 另外, 本女性卫生用品同时适用于我国 南方和北方人群, 适用范围广, 且不易致人过敏。  No 115 0 100 % The above experiments, clinical observations and use effects show that: the hygienic article of the invention has good prevention, inhibition and treatment for various vaginitis, pelvic inflammatory disease and the resulting symptoms of genital itching and redness. effect. In addition, this feminine hygiene product is suitable for both the southern and northern populations of China, and has a wide range of applications and is not easy to cause allergies.
再者, 由于本发明中的女性卫生用品与市售药用同类产品相比, 其中包含的中药种类减少, 这样经使用抛弃后, 其上的药物流失对环 境造成的破坏会大大减小。  Further, since the feminine hygiene product of the present invention is reduced in the amount of the traditional Chinese medicine contained in the commercially available pharmaceutical similar product, the damage caused by the drug loss on the environment is greatly reduced.
本领域普通技术人员可以理解的是, 基于本发明产品的结构及性 能, 其用途并不限于上文所述的范围, 还可以用于吸收婴儿尿液和吸 收各类患者体液、 伤部感染所致液体等。  It will be understood by those skilled in the art that, based on the structure and performance of the product of the present invention, the use thereof is not limited to the above-mentioned range, and can also be used for absorbing baby urine and absorbing various body fluids and wound infections of various patients. Cause liquid and so on.

Claims

权利要求 Rights request
1.一种女性卫生用品, 其包括透液性表层、 位于透液性表层下方 的吸液层以及位于所述吸液层下方的不透液性粘附层, 其特征在于, 透液性表层外表面包括有水片。 A feminine hygiene product comprising a liquid permeable surface layer, a liquid absorbing layer located below the liquid permeable surface layer, and a liquid-impermeable adhesive layer under the liquid absorbing layer, characterized by a liquid permeable surface layer The outer surface includes a water sheet.
2.权利要求 1所述的女性卫生用品, 其特征在于, 所述卫生用品 还可包括在不透液性粘附层外表面粘附的离型纸。  The feminine hygiene article according to claim 1, wherein the sanitary article further comprises a release paper adhered to the outer surface of the liquid-impermeable adhesive layer.
3.权利要求 1或 2所述的女性卫生用品, 其特征在于, 所述透液 性表层外表面包括的水片量为 0. 0010g/p -约 0. 0050g/po 0010g/p -约0. 0050g/p o The amount of the water-repellent surface of the liquid-permeable surface layer is 0. 0010g / p - about 0. 0050g / p o
4.权利要求 3所述的女性卫生用品, 其特征在于, 透液性表层外 表面包括的水片量为约 0. 00300g/p-约 0. 00480g/po 00300g/p-约0. 00480g/p o The amount of the water-repellent surface of the liquid-permeable surface layer is about 0. 00300g / p - about 0. 00480g / p o
5.权利要求 3所迷的女性卫生用品, 其特征在于, 透液性表层外 表面包括的冰片量为约 0. 00101g/p -約 0. 00157g/po 00101g/p - about 0. 00157g / p o 00101g / p - about 0. 00157g / p o
6. 一种制备权利要求 1所述的女性卫生用品的方法, 包括如下步 骤: 制备卫生用品吸液层; 将卫生用品吸液层与透液性表层粘结; 在 已与卫生用品吸液层粘结的透液性表层的外表面上, 施用由;水片与酒 精组成的药液; 将卫生用品吸液屋的另一面与不透液性粘附层粘贴。  6. A method of preparing the feminine hygiene product according to claim 1, comprising the steps of: preparing a liquid absorbing layer of the sanitary article; bonding the liquid absorbing layer of the sanitary article to the liquid permeable surface layer; and absorbing the liquid layer with the sanitary article On the outer surface of the bonded liquid-permeable surface layer, a liquid medicine composed of a water piece and an alcohol is applied; and the other side of the liquid absorbent house is attached to the liquid-impermeable adhesive layer.
7.权利要求 6的制备女性卫生用品的方法, 还包括粘贴吸水层和 不透液性粘附层后在不透液性粘附层上粘附离型纸的步骤。  The method of preparing a feminine hygiene article according to claim 6, further comprising the step of adhering the release paper to the liquid-impermeable adhesive layer after the water-absorbing layer and the liquid-impermeable adhesive layer are pasted.
8.权利要求 6的制备女性卫生用品的方法, 还包括在透液性表层 的外表面上施用由冰片与酒精组成的药液之后进行干燥的步骤。  A method of preparing a feminine hygiene article according to claim 6, further comprising the step of applying a liquid medicine consisting of borneol and alcohol on the outer surface of the liquid permeable surface layer followed by drying.
9.权利要求 6的制备女性卫生用品的方法, 其特征在于, 在所述 女性卫生用品透液性表层的外表面上施用的药液浓度为约 4: 100 g/ml -约 6: 100g/ml o 9. The method of preparing a feminine hygiene article according to claim 6, wherein a concentration of the chemical solution applied on the outer surface of the liquid pervious surface layer of the feminine hygiene product is from about 4:100 g/ml to about 6:100 g/ Ml o
10·权利要求 6的制备女性卫生用品的方法,其特征在于,所述酒 精浓度为 75 %。  A method of preparing a feminine hygiene product according to claim 6, wherein the alcohol concentration is 75 %.
PCT/CN2006/001760 2006-07-19 2006-07-19 Female sanitary article and its manufacturing method WO2008011755A1 (en)

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