WO2007134117A3 - Détection de polymorphismes d'acides aminés simples par marquage isotopique et spectrométrie de masse - Google Patents

Détection de polymorphismes d'acides aminés simples par marquage isotopique et spectrométrie de masse Download PDF

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Publication number
WO2007134117A3
WO2007134117A3 PCT/US2007/068584 US2007068584W WO2007134117A3 WO 2007134117 A3 WO2007134117 A3 WO 2007134117A3 US 2007068584 W US2007068584 W US 2007068584W WO 2007134117 A3 WO2007134117 A3 WO 2007134117A3
Authority
WO
WIPO (PCT)
Prior art keywords
amino acid
mass spectrometry
single amino
isotopic labeling
acid polymorphisms
Prior art date
Application number
PCT/US2007/068584
Other languages
English (en)
Other versions
WO2007134117A2 (fr
Inventor
David E Clemmer
Stephen J Valentine
Original Assignee
Univ Indiana Res & Tech Corp
Predictive Physiology And Medi
David E Clemmer
Stephen J Valentine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Indiana Res & Tech Corp, Predictive Physiology And Medi, David E Clemmer, Stephen J Valentine filed Critical Univ Indiana Res & Tech Corp
Publication of WO2007134117A2 publication Critical patent/WO2007134117A2/fr
Publication of WO2007134117A3 publication Critical patent/WO2007134117A3/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/976—Trypsin; Chymotrypsin
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Hematology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne une combinaison de techniques de marquage isotopique et de spectrométrie de masse/tube de dérive à champ fractionné, permettant d'identifier des polymorphismes d'acides aminés simples (SAAP).
PCT/US2007/068584 2006-05-09 2007-05-09 Détection de polymorphismes d'acides aminés simples par marquage isotopique et spectrométrie de masse WO2007134117A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79940606P 2006-05-09 2006-05-09
US60/799,406 2006-05-09

Publications (2)

Publication Number Publication Date
WO2007134117A2 WO2007134117A2 (fr) 2007-11-22
WO2007134117A3 true WO2007134117A3 (fr) 2008-02-21

Family

ID=38694678

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/068584 WO2007134117A2 (fr) 2006-05-09 2007-05-09 Détection de polymorphismes d'acides aminés simples par marquage isotopique et spectrométrie de masse

Country Status (1)

Country Link
WO (1) WO2007134117A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7400139B1 (ja) 2022-06-02 2023-12-18 山東省食品薬品検験研究院 枝角種属由来を高速で鑑別する特徴的ポリペプチドライブラリー及びその使用

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2794248C (fr) 2010-03-24 2018-02-20 Glendon John Parker Procedes pour conduire une analyse genetique utilisant le polymorphisme de proteine
CN114591399B (zh) * 2022-03-25 2023-05-09 山东省食品药品检验研究院 一种中药制剂中筛查驯鹿鹿茸投料的特征多肽及其应用

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GATLIN ET AL.: "Automated identification of amino acid sequence variations in proteins by HPLC/microspray tandem spectrometry", ANAL. CHEM., vol. 72, no. 4, February 2000 (2000-02-01), pages 757 - 763 *
JULKA ET AL.: "Quantification in proteomics through stable isotope coding: A review", JOURNAL OF PROTEOME RESEARCH, vol. 3, no. 3, May 2004 (2004-05-01) - June 2004 (2004-06-01), pages 350 - 363 *
LIU ET AL.: "Technique Review: Development of high throughput dispersive LC-ion mobility-TOFMS techniques for analyzing the human plasma proteome", BRIEFINGS IN FUNCTIONAL GENOMICS AND PROTEOMICS, vol. 3, no. 2, August 2004 (2004-08-01), pages 177 - 186 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7400139B1 (ja) 2022-06-02 2023-12-18 山東省食品薬品検験研究院 枝角種属由来を高速で鑑別する特徴的ポリペプチドライブラリー及びその使用

Also Published As

Publication number Publication date
WO2007134117A2 (fr) 2007-11-22

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