WO2007107385A3 - Inhibitoren der löslichen adenylatzyklase - Google Patents
Inhibitoren der löslichen adenylatzyklase Download PDFInfo
- Publication number
- WO2007107385A3 WO2007107385A3 PCT/EP2007/002708 EP2007002708W WO2007107385A3 WO 2007107385 A3 WO2007107385 A3 WO 2007107385A3 EP 2007002708 W EP2007002708 W EP 2007002708W WO 2007107385 A3 WO2007107385 A3 WO 2007107385A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- adenylate cyclase
- cyclase inhibitors
- soluble adenylate
- soluble
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07723654A EP2001847A2 (de) | 2006-03-23 | 2007-03-22 | Inhibitoren der löslichen adenylatzyklase |
CA002646650A CA2646650A1 (en) | 2006-03-23 | 2007-03-22 | Soluble adenylate cyclase inhibitors |
JP2009500787A JP2009531319A (ja) | 2006-03-23 | 2007-03-22 | 可溶性アデニレートシクラーゼ阻害剤 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006014320.5 | 2006-03-23 | ||
DE102006014320A DE102006014320B4 (de) | 2006-03-23 | 2006-03-23 | Inhibitoren der löslichen Adenylatzklase |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007107385A2 WO2007107385A2 (de) | 2007-09-27 |
WO2007107385A3 true WO2007107385A3 (de) | 2007-11-29 |
Family
ID=38229991
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2007/002708 WO2007107385A2 (de) | 2006-03-23 | 2007-03-22 | Inhibitoren der löslichen adenylatzyklase |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP2001847A2 (de) |
JP (1) | JP2009531319A (de) |
KR (1) | KR20090007351A (de) |
CN (1) | CN101448789A (de) |
AR (1) | AR063661A1 (de) |
CA (1) | CA2646650A1 (de) |
DE (1) | DE102006014320B4 (de) |
DO (1) | DOP2007000059A (de) |
PE (1) | PE20080012A1 (de) |
TW (1) | TW200815347A (de) |
UY (1) | UY30236A1 (de) |
WO (1) | WO2007107385A2 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2036906A1 (de) * | 2007-09-05 | 2009-03-18 | Bayer Schering Pharma Aktiengesellschaft | Azaindole als Inhibitoren der löslichen Adenylatzyklase |
CN108096244B (zh) * | 2018-01-25 | 2020-11-24 | 昆明医科大学 | 1-氢-2-吲哚酮-3-苄基/取代苄基-3-甲酸酯类化合物的用途 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005030715A1 (en) * | 2003-09-25 | 2005-04-07 | Wyeth | Substituted sulfonamide-indole-2-carboxylic acid derivatives as pai-1 inhibitors |
WO2006010008A1 (en) * | 2004-06-22 | 2006-01-26 | Vertex Pharmaceuticals Incorporated | Heterocyclic derivatives for modulation of calcium channels |
WO2006032541A1 (de) * | 2004-09-24 | 2006-03-30 | Bayer Schering Pharma Aktiengesellschaft | Indol derivative als inhibitoren der löslichen adenylatzyklase |
-
2006
- 2006-03-23 DE DE102006014320A patent/DE102006014320B4/de not_active Expired - Fee Related
-
2007
- 2007-03-22 WO PCT/EP2007/002708 patent/WO2007107385A2/de active Application Filing
- 2007-03-22 EP EP07723654A patent/EP2001847A2/de not_active Withdrawn
- 2007-03-22 JP JP2009500787A patent/JP2009531319A/ja active Pending
- 2007-03-22 CN CNA2007800187317A patent/CN101448789A/zh active Pending
- 2007-03-22 KR KR1020087025818A patent/KR20090007351A/ko not_active Application Discontinuation
- 2007-03-22 CA CA002646650A patent/CA2646650A1/en not_active Abandoned
- 2007-03-23 TW TW096110185A patent/TW200815347A/zh unknown
- 2007-03-23 UY UY30236A patent/UY30236A1/es not_active Application Discontinuation
- 2007-03-23 DO DO2007000059A patent/DOP2007000059A/es unknown
- 2007-03-23 AR ARP070101194A patent/AR063661A1/es unknown
- 2007-03-23 PE PE2007000335A patent/PE20080012A1/es not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005030715A1 (en) * | 2003-09-25 | 2005-04-07 | Wyeth | Substituted sulfonamide-indole-2-carboxylic acid derivatives as pai-1 inhibitors |
WO2006010008A1 (en) * | 2004-06-22 | 2006-01-26 | Vertex Pharmaceuticals Incorporated | Heterocyclic derivatives for modulation of calcium channels |
WO2006032541A1 (de) * | 2004-09-24 | 2006-03-30 | Bayer Schering Pharma Aktiengesellschaft | Indol derivative als inhibitoren der löslichen adenylatzyklase |
Also Published As
Publication number | Publication date |
---|---|
WO2007107385A2 (de) | 2007-09-27 |
KR20090007351A (ko) | 2009-01-16 |
DOP2007000059A (es) | 2007-09-30 |
DE102006014320A1 (de) | 2007-09-27 |
UY30236A1 (es) | 2007-10-31 |
DE102006014320B4 (de) | 2009-01-22 |
AR063661A1 (es) | 2009-02-11 |
TW200815347A (en) | 2008-04-01 |
CN101448789A (zh) | 2009-06-03 |
PE20080012A1 (es) | 2008-04-03 |
CA2646650A1 (en) | 2007-09-27 |
EP2001847A2 (de) | 2008-12-17 |
JP2009531319A (ja) | 2009-09-03 |
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