WO2007106612A3 - Determination d'une mesure d'un produit de glycation ou d'un etat pathologique par fluorescence tissulaire - Google Patents

Determination d'une mesure d'un produit de glycation ou d'un etat pathologique par fluorescence tissulaire Download PDF

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Publication number
WO2007106612A3
WO2007106612A3 PCT/US2007/060997 US2007060997W WO2007106612A3 WO 2007106612 A3 WO2007106612 A3 WO 2007106612A3 US 2007060997 W US2007060997 W US 2007060997W WO 2007106612 A3 WO2007106612 A3 WO 2007106612A3
Authority
WO
WIPO (PCT)
Prior art keywords
light
optical probe
vivo tissue
tissue
properties
Prior art date
Application number
PCT/US2007/060997
Other languages
English (en)
Other versions
WO2007106612A2 (fr
Inventor
Marwood Neal Ediger
John D Maynard
Robert D Johnson
Mauro Maurizio Andrea Di
Original Assignee
Veralight Inc
Marwood Neal Ediger
John D Maynard
Robert D Johnson
Mauro Maurizio Andrea Di
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Veralight Inc, Marwood Neal Ediger, John D Maynard, Robert D Johnson, Mauro Maurizio Andrea Di filed Critical Veralight Inc
Publication of WO2007106612A2 publication Critical patent/WO2007106612A2/fr
Publication of WO2007106612A3 publication Critical patent/WO2007106612A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/443—Evaluating skin constituents, e.g. elastin, melanin, water
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/445—Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

Sous certains modes de réalisation, la présente invention concerne un appareil approprié pour déterminer les propriétés d'un tissu in vivo à partir de données spectrales fournies par le tissu. Un système d'irradiation fournit de la lumière suivant une pluralité de plages de large spectre, lesquelles sont communiquées à une sonde optique. La sonde optique reçoit la lumière du système d'irradiation et la transmet au tissu in vivo; elle reçoit, en réponse à la lumière de large spectre, une lumière réfléchie par réflexion diffuse émise par fluorescence par le tissu in vivo, ou une combinaison de telles lumières. La sonde optique communique la lumière à un spectrographe qui génère un signal représentatif des propriétés spectrales de la lumière. Un système d'analyse détermine une propriété du tissu in vivo à partir des propriétés spectrales. Un dispositif d'étalonnage est monté de telle sorte qu'il soit en communication optique périodique avec la sonde optique.
PCT/US2007/060997 2006-03-10 2007-01-24 Determination d'une mesure d'un produit de glycation ou d'un etat pathologique par fluorescence tissulaire WO2007106612A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78163806P 2006-03-10 2006-03-10
US60/781,638 2006-03-10
US11/624,214 2007-01-17
US11/624,214 US20070276199A1 (en) 2002-04-04 2007-01-17 Determination of a Measure of a Glycation End-Product or Disease State Using Tissue Fluorescence

Publications (2)

Publication Number Publication Date
WO2007106612A2 WO2007106612A2 (fr) 2007-09-20
WO2007106612A3 true WO2007106612A3 (fr) 2007-12-13

Family

ID=38510124

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/060997 WO2007106612A2 (fr) 2006-03-10 2007-01-24 Determination d'une mesure d'un produit de glycation ou d'un etat pathologique par fluorescence tissulaire

Country Status (2)

Country Link
US (1) US20070276199A1 (fr)
WO (1) WO2007106612A2 (fr)

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US20110313296A9 (en) * 2001-04-11 2011-12-22 Johnson Robert D Method and Apparatus for Determination of a Measure of a Glycation End-Product or Disease State Using Tissue Fluorescence
TR201901658T4 (tr) 2008-05-20 2019-02-21 Univ Health Network Floresan bazli görüntüleme ve i̇zleme i̇çi̇n ci̇haz ve metot
US20100003664A1 (en) * 2008-07-01 2010-01-07 Lou Reinisch System for Glycated Protein Detection
US9060687B2 (en) 2009-10-02 2015-06-23 Sharp Kabushiki Kaisha Device for monitoring blood vessel conditions and method for monitoring same
WO2011114578A1 (fr) 2010-03-19 2011-09-22 シャープ株式会社 Dispositif de mesure, procédé de mesure, dispositif de traitement de résultats de mesure, système de mesure, procédé de traitement de résultats de mesure, programme de commande, et support d'enregistrement
JP5641773B2 (ja) * 2010-04-28 2014-12-17 キヤノン株式会社 測定装置
US20130217984A1 (en) * 2010-06-18 2013-08-22 Diagnoptics Holding B.V. Method and apparatus for determining an autofluorescence value of skin tissue
JP5384453B2 (ja) 2010-09-09 2014-01-08 シャープ株式会社 測定装置、測定システム、測定方法、制御プログラム、および、記録媒体
JP5290257B2 (ja) 2010-10-12 2013-09-18 シャープ株式会社 検出装置、検出方法、制御プログラムおよび記録媒体
US9155473B2 (en) * 2012-03-21 2015-10-13 Korea Electrotechnology Research Institute Reflection detection type measurement apparatus for skin autofluorescence
US9888855B2 (en) * 2013-03-18 2018-02-13 Korea Electrotechnology Research Institute Reflection detection type measurement apparatus and method for skin autofluorescence
US20150201840A1 (en) * 2013-03-18 2015-07-23 Korea Electrotechnology Research Institute Reflection detection type measurement apparatus for skin autofluorescence
WO2016011534A1 (fr) 2014-07-24 2016-01-28 University Health Network Collecte et analyse de données à des fins de diagnostic
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Publication number Publication date
WO2007106612A2 (fr) 2007-09-20
US20070276199A1 (en) 2007-11-29

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