WO2007103538A3 - Procedes de marquage d'anticorps multiples et utilisations desdits procedes - Google Patents

Procedes de marquage d'anticorps multiples et utilisations desdits procedes Download PDF

Info

Publication number
WO2007103538A3
WO2007103538A3 PCT/US2007/005996 US2007005996W WO2007103538A3 WO 2007103538 A3 WO2007103538 A3 WO 2007103538A3 US 2007005996 W US2007005996 W US 2007005996W WO 2007103538 A3 WO2007103538 A3 WO 2007103538A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
antibody labeling
multiple antibody
organisms
cell
Prior art date
Application number
PCT/US2007/005996
Other languages
English (en)
Other versions
WO2007103538A2 (fr
Inventor
David N Krag
Edward A Manna
Original Assignee
Univ Vermont
David N Krag
Edward A Manna
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Vermont, David N Krag, Edward A Manna filed Critical Univ Vermont
Publication of WO2007103538A2 publication Critical patent/WO2007103538A2/fr
Publication of WO2007103538A3 publication Critical patent/WO2007103538A3/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne, en partie, des procédés d'utilisation d'anticorps multiples produits dans deux espèces différentes ou plus, pour marquer et identifier des cellules, des organismes et des cibles supplémentaires. En outre, l'invention a trait, en partie, à des dosages de diagnostic pour des maladies telles que le cancer, à l'identification d'organismes ou de contaminants dans des échantillons, et à des dosages permettant d'évaluer le statut des cellules, notamment la différenciation des cellules et le lignage des cellules.
PCT/US2007/005996 2006-03-08 2007-03-08 Procedes de marquage d'anticorps multiples et utilisations desdits procedes WO2007103538A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78033106P 2006-03-08 2006-03-08
US60/780,331 2006-03-08

Publications (2)

Publication Number Publication Date
WO2007103538A2 WO2007103538A2 (fr) 2007-09-13
WO2007103538A3 true WO2007103538A3 (fr) 2007-12-06

Family

ID=38372382

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/005996 WO2007103538A2 (fr) 2006-03-08 2007-03-08 Procedes de marquage d'anticorps multiples et utilisations desdits procedes

Country Status (1)

Country Link
WO (1) WO2007103538A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5580142B2 (ja) * 2010-08-24 2014-08-27 田中貴金属工業株式会社 免疫測定法による尿中抗原の検出方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683197A (en) * 1981-07-16 1987-07-28 Hoffmann-La Roche Inc. Detection method for occult blood

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683197A (en) * 1981-07-16 1987-07-28 Hoffmann-La Roche Inc. Detection method for occult blood

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DAVID N KRAG ET AL: "The Detection of Isolated Tumor Cells in Bone Marrow Comparing Bright-Field Immunocytochemistry and Multicolor Immunofluorescence", ANNALS OF SURGICAL ONCOLOGY, SPRINGER-VERLAG, NE, vol. 12, no. 9, 1 September 2005 (2005-09-01), pages 753 - 760, XP019369729, ISSN: 1534-4681 *
M. LAGRANGE ET AL: "Non-specifically labelled cells that simulate bone marrow metastases in patients with non-metastatic breast cancer.", JOURNAL OF CLINICAL PATHOLOGY MAR 1997, vol. 50, no. 3, March 1997 (1997-03-01), England, pages 206 - 211, XP002448051, ISSN: 0021-9746 *

Also Published As

Publication number Publication date
WO2007103538A2 (fr) 2007-09-13

Similar Documents

Publication Publication Date Title
WO2009048530A3 (fr) Dosages à base de particules hautement multiplexées
WO2012021795A3 (fr) Biomarqueurs du cancer du pancréas et leurs utilisations
WO2009105670A3 (fr) Subtrats pour des dosages multiplexés et utilisations de ceux-ci
WO2006124641A3 (fr) Anticorps diriges contre la mesotheline utiles pour des dosages immunologiques
WO2010019414A3 (fr) Détection d'acide nucléique
EP2333116A3 (fr) Marqueurs de rejet de greffe de rein et de lésions rénales
WO2008073316A3 (fr) Identification et isolation de cellules souches de leucémie myéloïde aiguë
WO2007086900A3 (fr) Analyses de recherche de stilbazium
WO2007039319A3 (fr) Dispositif d'analyse pour identifier rapidement des agents pathogenes
EP3206031A3 (fr) Procédés, réactifs et kits pour phénotypage immunologique par cytométrie de flux
WO2009129505A3 (fr) Compositions, procédé et trousses utilisant des sondes synthétiques pour déterminer la présence d'un acide nucléique voulu
WO2007135368A3 (fr) Composés de type teinte et application de leurs conjugués marqués
EP3275901A8 (fr) Procédés de cellules souches embryonnaires humaines et expression podxl
WO2007010379A3 (fr) Evaluation calorimetrique de micro-organismes et utilisation
WO2015035239A3 (fr) Réactifs et procédés de criblage mps i, ii, iiia, iiib, iva, vi, et vii
WO2008140581A3 (fr) Systèmes et procédés pour préparer et analyser des échantillons
NZ609824A (en) Immunochromatography devices, methods and kits
WO2009005536A3 (fr) Procédure de capture de cellules bactériennes entières et procédés d'analyse d'échantillons de bactéries
WO2007085923A8 (fr) Nouvelles protéines fluorescentes et procédés d'utilisation de celles-ci
WO2006076687A3 (fr) Dosages elisa utilisant des reactifs peptides specifiques du prion
AR067135A1 (es) Metodos para aislar arn de fragmento largo de muestras fijas
WO2010092164A3 (fr) Adn bactérien en tant que marqueurs de maladie cardiovasculaire et/ou métabolique
EP2232319B8 (fr) Procédé et système pour identifier des lames porte-échantillon biologique en utilisant des empreintes de lame unique
WO2019139980A8 (fr) Procédés de mesure d'un analyte et/ou d'une protéine dans des échantillons biologiques
EP1722231A3 (fr) Méthode d'identification de cellules somatiques dérivées

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 07752679

Country of ref document: EP

Kind code of ref document: A2