WO2007093295A2 - Formulation huile dans eau servant à lutter contre les arthropodes et les plathelminthes - Google Patents

Formulation huile dans eau servant à lutter contre les arthropodes et les plathelminthes Download PDF

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Publication number
WO2007093295A2
WO2007093295A2 PCT/EP2007/000953 EP2007000953W WO2007093295A2 WO 2007093295 A2 WO2007093295 A2 WO 2007093295A2 EP 2007000953 W EP2007000953 W EP 2007000953W WO 2007093295 A2 WO2007093295 A2 WO 2007093295A2
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WO
WIPO (PCT)
Prior art keywords
oil
formulation according
mixtures
acid
weight
Prior art date
Application number
PCT/EP2007/000953
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German (de)
English (en)
Other versions
WO2007093295A3 (fr
Inventor
Thomas Gernot
Petra Krebs
Friedrich Koch
Nikolaus Müller
Beate Tombeux
Original Assignee
Saltigo Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Saltigo Gmbh filed Critical Saltigo Gmbh
Publication of WO2007093295A2 publication Critical patent/WO2007093295A2/fr
Publication of WO2007093295A3 publication Critical patent/WO2007093295A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A61K8/894—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants

Definitions

  • the present invention relates to a formulation for arthropod and platelet lineage defense based on piperidine derivatives in oil-in-water formulations.
  • lotions based on these piperidine compounds as well as water and a volatile alcohol component have become established.
  • alcohol physiologically compatible volatile solvents are used here.
  • phenethyl alcohol and benzyl alcohol include monofunctional and polyfunctional aliphatic alcohols (alkanols, alkanediols, alkanetriols).
  • ethanol propanol, isopropanol, n-butanol, sec-butanol, propylene glycol, polypropylene glycol, ethylene glycol, polyethylene glycol, ethylene or propylene oxide based copolymeric polyether polyols (both block copolymers and random copolymers), 2-ethyl-1,3 Hexanediol, glycerin, trimethylolpropane, etc.
  • solubility series is given from a ternary system (icaridine, alcohol, water). These mixtures give each stable lotions.
  • the viscosity of the formulations was determined in accordance with DIN 53019 of November 1983:
  • oil-in-water emulsions have been established in the pharmaceutical and cosmetic industries. They consist essentially of ternary systems of water, an oil component (for example a hydrocarbon mixture, mineral oil, cyclomethicone, linseed oil, apicose kernel, oleic acid, pinienol, ohvenol , Silicone oils, tallow, tung oil, mink oil, oleic acid, etc.) and a suitable mediating component in the form of a surface-active substance, for example an emulsifier or emulsifier system
  • an oil component for example a hydrocarbon mixture, mineral oil, cyclomethicone, linseed oil, apicose kernel, oleic acid, pinienol, ohvenol , Silicone oils, tallow, tung oil, mink oil, oleic acid, etc.
  • a suitable mediating component in the form of a surface-active substance, for example an emulsifier
  • Insect repellent formulations as emulsions based on the active ingredient N, N-diethyl-m-toluamide (DEET) are already known.
  • DEET N-diethyl-m-toluamide
  • US Pat. No. 5,916,541 A1 describes emulsions containing insect repellent, a sunscreen agent and a film former.
  • US Pat. No. 5,989,529 A1 also describes emulsions which are block polymers
  • US 5,980,871 A1 describes emulsions containing an insect repellent active ingredient, an inorganic sunscreen agent and an anionic emulsifier
  • the invention therefore has for its object to provide stable oil-in-water formulations which have a low solvent / alcohol content and optionally a high viscosity
  • the formulations are clear and stable.
  • the formulation preferably has a viscosity of> 20 mPas measured according to DIN 53019 from November 1983.
  • the formulation preferably additionally contains from 0.1% to 20% by weight of N-methylpyrrolidone, phenethyl alcohol, benzyl alcohol, an aliphatic alcohol, aliphatic ethers, aliphatic polyethers and / or mixtures thereof. This can increase the stability.
  • the formulation preferably additionally contains 0.1 to 20% by weight of ethanol, propanol, isopropanol, n-butanol, sec-butanol, propylene glycol, polypropylene glycol, ethylene glycol, polyethylene glycol, copolymeric polyether polyols based on ethylene or propylene oxide, 2-ethyl-1, 3-hexanediol, glycerol, trimethylolpropane and / or mixtures thereof.
  • repellent is preferably a piperidine derivative of the general formula:
  • Ri 'and R 2 ' are each independently alkyl, alkenyl, alkynyl, hydroxyalkyl, hydroxyalkenyl. Hydroxyalkiiryl. Cycloalkyl. Cycloalkenyl, cycloalkynyl, cycloalkoxy, cycloalkenoxy and cycloalkynoxy, and
  • n 0 or 1 or mixtures thereof are used.
  • a piperidine derivative of the general formula is used where Ri 'and R 2 ' independently of one another for Ci-Ci 2 alkyl, C 2 -C 20 alkenyl, C 2 -C 20 alkynyl, Ci-Ci 2 hydroxyalkyl, C 3 -C 20 hydroxyalkenyl, C 3 -C 20 hydroxyalkynyl C 3 -C 02 cycloalkyl, C 3 -C 20 cycloalkenyl, C 3 -C 20 cycloalkynyl, C 3 -C 20 cycloalkoxy, C 3 -C 20 cycloalkenoxy and C 3 -C 20 is cycloalkynoxy, and n is 0 or 1, or mixtures thereof.
  • the repellent used is preferably 1-piperidinecarboxylic acid 2-hydroxyethyl-1-methylpropyl ester (icaridine) and 1- (3-cyclohexen-1-ylcarbonyl) -2-methylpiperidine both as a racemic mixture and as a chiral compound, for example (1S, 2'S). - l- (3-cyclohexen-1-ylcarbonyl) -2-methylpiperidine used.
  • oils are preferably the repellent itself, mineral oils, polycyclic aromatic hydrocarbons, paraffin oils, silicone oils such as polysiloxane, cyclosiloxane, methicone, animal oils such as mink oil, fish oils, natural vegetable oils such as olive oil, sesame oil, linseed oil, palm oil, sunflower oil, peanut oil, rapeseed oil, soybean oil, coconut oil , Paitnkernfett, peach kernel oil, almond oil, castor oil, dehydrated castor oil, pine oil, tall oil and / or mixtures thereof used.
  • additional aliphatic esters are preferably synthetic triglycerides such as caprylic / Caprinkladlycerid, Triglyceridgemische with vegetable fatty acids of chain length C 8 - I2 or other specially selected natural fatty acids, Partialglyceridgemische saturated or unsaturated possibly hydroxyl-containing fatty acids, mono- and diglycerides of Cs / i 0 - fatty acids, Fatty acid esters such as ethyl stearate, di-n-butyl adipate, lauric acid hexyl ester, dipropylene glycol pelargonate, cetearyl glucoside, cetearath-15, glyceryl stearate, glyceryl cetearate, isopropyl palmitate, middle chain branched chain fatty acid ester with saturated fatty alcohols of chain length Ci6-i8, Isopropyl myristate, Isopropylpahnitat, capry
  • Adipic diisopropyl ester Adipic diisopropyl ester, the latter related ester mixtures including fatty alcohols such as isotridecyl alcohol, 2-octyldodecanol, cetylstearyl alcohol, oleyl alcohol and / or mixtures used of it.
  • Cetearyl glucosides are very particularly preferred as aliphatic esters. Cetearath-15, glyceryl stearates, glyceryl cetearaths, isopropyl palmitates and / or mixtures thereof.
  • Particularly preferred is a formulation containing as a mixture of 1-piperidinecarboxylic acid 2-hydroxyethyl-1-methylpropyl ester, cereraryl glucoside, carbomer and water.
  • Particularly preferred is a formulation containing as a mixture 1-piperidinecarboxylic acid 2-hydroxyethyl-1-methylpropyl, silicone polyether, isopropyl palmitate, polydimethylsiloxane, acrylic acid polymer, polycyclic aromatic hydrocarbons and water.
  • Oxybenzone, sulisobenzone (2-hydroxy-4-methylbenzophenone-5-sulfonic acid), dioxybenzene (2,2'-dihydroxy-4-methoxybenzophenone), menthylanthranilate, avobenzone, para-aminobenzoic acid are particularly preferred as components for producing a UV filter effect , octyl methoxycinnamate, octocrylene, TEA-sahcylat Drometrizoltrisiloxan, Octylsahcylat, homomenthyl salicylate, octyl dimethyl PABA, titanium dioxide, Butyhnethoxydibenzoylmethan, diendikamfersulfonkla oxide, octyl, terephthalyl, ethyl PABA, hydroxymethylphenyl
  • biocides are preferably additionally used.
  • Particularly preferred biocides are benzyl alcohol, trichlorobutanol, o-phenylphenol, para-hydroxybenzoic acid methyl ester, para-hydroxybenzoic acid ethyl ester, para-hydroxybenzoic acid propyl ester, butyl para-hydroxybenzoate, n-butanol, propanol, isopropanol, ethanol and / or mixtures thereof.
  • antioxidants preference is given to using butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), tocopherol, sulfites, metabisulfites, such as potassium metabisulfite, ascorbic acid, and / or mixtures thereof.
  • thickeners are preferably used in addition.
  • Particularly preferred thickeners are carboxymethylcellulose, hydroxyethylcellulose, Methyl cellulose and other cellulose and starch derivatives, polyacrylates, polyvinyl acetate, vinyl acetate-crotonic acid copolymer, alginates, gelatin, pectin, casein, agar-agar, gum arabic, aloe vera, polyvinylpyrrolidone, polyvinyl alcohol, copolymers of methyl vinyl ether and maleic anhydride, polyethylene glycols, Polypropylene glycols, block and / or random copolymer of propylene and ethylene glycol units, waxes, colloidal silicic acids, and / or mixtures thereof used.
  • dyes or color pigments it is particularly preferred to use all dyes approved for human or animal use in dissolved or suspended form and as pigments all pigments approved for human or animal use in dissolved or suspended form, and / or mixtures thereof.
  • fragrances are preferably used in addition.
  • Fragrances used are particularly preferably perfume oils and other low-boiling substances which are approved for use on humans or animals, and / or mixtures thereof.
  • the invention also encompasses a process for preparing the formulation, characterized
  • That 1 to 40 weight percent of a repellant, 0 to 20 weight percent of an oil and 0 to 3 weight percent of a carbomer, acrylic acid polymer or their mixtures thereof are mixed together and then with
  • the invention also encompasses the use of the formulations for expelling arthropods and / or platelet mints.
  • the formulation is preferably used to ward off harmful or irritating sucking and biting arthropods, preferably insects, ticks and mites.
  • the sucking insects mainly include the mosquitoes (for example Aedes aegypti, Aedes vexans, Aedes taeniorhynchus, Aedes albopictus, Culex pipiens fatigans, Culex quinquefasciatus, Culex tarsalis, Anopheles albimanus, Anopheles dirus, Anopheles gambiae, Anopheles sinensis, Anopheles stephensi, Mansonia titillans), insect moths (for example Phlebotomus papatasii, Phlebotomus duboscqi), biting midges (for example Culicoides furens, Culicoides minimctatus), blackflies (for example Simulium damnosum, Simulium venustum), Lynxes (for example Stomoxys calcitrans), tsetse flies (for example Glossina mors
  • the biting insects include, essentially, cockroaches (for example, Blattella germanica, Periplaneta americana, Blatta orientalis, Supella longipalpa), beetles (for example, Sitiophilus granarius, Tenebrio molitor, Dermestes lardarius, Stegobium paniceum, Anobium punctatum, Hylotrupes bajulus), termites (e.g.
  • Example Reticulitermes lucifugus ants (for example Lasius niger, Monomorium pharaonis), wasps (for example Vespula germanica) and larvae of moths (for example Ephestia elutella, Ephestia cautella, Plodia interpunctella, Hofmannophila pseudospretella, Tineola bisselliella, Tinea pellionella, Trichophaga tapetzella ).
  • ants for example Lasius niger, Monomorium pharaonis
  • wasps for example Vespula germanica
  • larvae of moths for example Ephestia elutella, Ephestia cautella, Plodia interpunctella, Hofmannophila pseudospretella, Tineola bisselliella, Tinea pellionella, Trichophaga tapetzella ).
  • the other arthropods include ticks (eg Ixodes ricinus, Ixodes scapularis, Argas reflexus, Ornithodorus moubata, Ripicephalus sanguineus, Boophilius microplus, Amblyomma hebraeum) and mites (for example Sarcoptes scabiei, Dermatophagoides pteronyssinus, Dermatophagoides farinae, Dermanyssus gallinae, Acarus siro) ,
  • ticks eg Ixodes ricinus, Ixodes scapularis, Argas reflexus, Ornithodorus moubata, Ripicephalus sanguineus, Boophilius microplus, Amblyomma hebraeum
  • mites for example Sarcoptes scabiei, Dermatophagoides pteronyssinus, Dermatophagoides farinae, Dermanyssus gallinae, A
  • the formulations are preferably used against platelet mints, in particular against infectious stages of Plathehnintlien. Preference is given to the formulation for repelling plamelminths such as Schistosomahaematobium, Schistosoma japonicum, Trichobilharzia spp. and Ornithobilharzia spp., but also Echinostoma spp. used.
  • plamelminths such as Schistosomahaematobium, Schistosoma japonicum, Trichobilharzia spp. and Ornithobilharzia spp., but also Echinostoma spp. used.
  • the formulations are preferably used by applying to the skin of humans or animals by means of dripping, brushing, rubbing, spraying, by dipping / dipping, bathing or washing.
  • the formulations are preferably for impregnation of a carrier or encapsulation / microencapsulation in a shell of liposomes and / or ureas or
  • the carrier is preferably tissue.
  • the viscosity is determined according to DIN 53019 of November 1983.
  • the stability of the formulation was determined by the centrifuge microwave assay.
  • the test serves to evaluate the structure of disperse systems. The test method looks like this:
  • test sample of the formulation to be tested is acclimated after preparation for about 2 days at room temperature. Approximately 10 g of product are weighed from the test sample into a centrifuge tube (25 ml nominal volume).
  • the centrifuge tube is 114 (corresponding to an average power of 75 watts) irradiated 75 seconds with stage 1 of the apparatus AEG Micromat ® in the microwave. Subsequently, this sample is acclimated for one hour at room temperature and centrifuged for 11 minutes at 4350 revolutions / minute in an Eppendorf centrifuge 5403.
  • the test of the sample is done visually by the laboratory technician.
  • the sample is examined for homogeneity of the formulation. Differing appearance to the untreated sample, for example occurring phase separation or bubbles in the centrifuge tube are described.
  • a water-in-oil formulation of the following composition is prepared:
  • phase A is heated to 80 0 C.
  • phase B is slowly added at a temperature of about 25 0 C with vigorous stirring.
  • the mixture is then cooled to below 30 0 C with slow further stirring.
  • phase A is warmed to 60 0 C and mixed.
  • phase B is mixed with a temperature of about 35 ° C. and slowly added to phase A with vigorous stirring.
  • the mixture is then cooled to below 30 ° C. with slow further stirring.
  • a pH control is carried out and adjusted if necessary by means of aqueous sodium hydroxide solution in the range pH 5.5 to 7.0.
  • phase A is warmed to 55 0 C and mixed.
  • phase B is mixed at a temperature of about 35 ° C. and slowly added with vigorous stirring.
  • the mixture is then cooled to below 30 0 C with slow further stirring.
  • a pH control is carried out and adjusted if necessary by means of aqueous sodium hydroxide solution in the range pH 5.5 to 7.0.
  • phase B is mixed at room temperature. Subsequently, phase A at a temperature of about 25 0 C 71.83% wt .-% mixed slowly added with vigorous stirring to phase A. The mixture is then cooled to below 25 0 C with slow further stirring.
  • a pH control is carried out and adjusted if necessary by means of aqueous sodium hydroxide solution in the range pH 5.5 to 7.0.
  • Example 5 An oil-in-water formulation of the following composition is prepared:
  • phase B is mixed at room temperature.
  • Phase A is then mixed at room temperature and slowly added to phase B with vigorous stirring.
  • the mixture is then cooled to below 25 0 C with slow further stirring.
  • a pH control is carried out and adjusted if necessary by means of aqueous sodium hydroxide solution in the range pH 5.5 to 7.0.
  • Phase B 10% wt .-% l-piperidinecarboxylic acid-2-hydroxyethyl-l-methylpropyl (Icaridin, Bayrepel ®)
  • phase A is mixed at room temperature.
  • phase B is mixed with a temperature of about 25 0 C and slowly added with vigorous stirring.
  • the mixture is then cooled to below 25 ° C. with slow further stirring.
  • a pH control is carried out and adjusted if necessary by means of aqueous sodium hydroxide solution in the range pH 5.5 to 7.0.
  • phase A is mixed at room temperature.
  • phase B is mixed and added slowly at a temperature of about 25 ° C. with vigorous stirring.
  • the mixture is then cooled to below 25 0 C with slow further stirring.
  • a water in oil formulation of the following composition is prepared:
  • acrylic acid polymer (Carbopol Ultrez 10)
  • phase A is mixed at room temperature.
  • phase B is mixed and slowly added at a temperature of about 25 0 C with vigorous stirring.
  • the mixture is then cooled to below 25 0 C with slow further stirring.
  • a pH control is carried out and adjusted if necessary by means of aqueous sodium hydroxide solution in the range pH 5.5 to 7.0.

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne une formulation servant à lutter contre les arthropodes et les plathelminthes, à base de dérivés de pipéridine dans des formulations huile dans eau.
PCT/EP2007/000953 2006-02-16 2007-02-05 Formulation huile dans eau servant à lutter contre les arthropodes et les plathelminthes WO2007093295A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006007549.8 2006-02-16
DE200610007549 DE102006007549A1 (de) 2006-02-16 2006-02-16 Öl-in-Wasser-Formulierung zur Arthropoden- und Plathelminthen-Abwehr

Publications (2)

Publication Number Publication Date
WO2007093295A2 true WO2007093295A2 (fr) 2007-08-23
WO2007093295A3 WO2007093295A3 (fr) 2007-12-21

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Application Number Title Priority Date Filing Date
PCT/EP2007/000953 WO2007093295A2 (fr) 2006-02-16 2007-02-05 Formulation huile dans eau servant à lutter contre les arthropodes et les plathelminthes

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DE (1) DE102006007549A1 (fr)
WO (1) WO2007093295A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2218328A1 (fr) * 2009-02-17 2010-08-18 Cognis IP Management GmbH Compositions agrochimiques à base d'huile avec une viscosité améliorée

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102022109353A1 (de) * 2022-04-14 2023-10-19 Andrea Krecklow Repellent für Pferde

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002002087A2 (fr) * 2000-07-06 2002-01-10 Bayer Aktiengesellschaft Produits anthelminthiques permettant de prevenir les infections parasitaires chez l'homme et l'animal ii
WO2003020232A2 (fr) * 2001-08-29 2003-03-13 Beiersdorf Ag Stabilisation de preparations cosmetiques ou dermatologiques contenant des substances actives repulsives
US6562841B1 (en) * 2000-10-19 2003-05-13 The United States Of America As Represented By The Secretary Of Agriculture Methods and compositions for repelling arthropods
WO2005002537A2 (fr) * 2003-07-01 2005-01-13 Hygieia Healthcare Limited Perfectionnements apportes a une matiere organique ou concernant celle-ci
EP1738745A1 (fr) * 2005-06-27 2007-01-03 Beiersdorf AG Emulsion insectifuge
EP1762221A1 (fr) * 2005-07-20 2007-03-14 Beiersdorf AG Insectifuge à longue durée
WO2007079822A1 (fr) * 2005-12-22 2007-07-19 Merck Patent Gmbh Melange d'agents insectifuges
WO2007093298A1 (fr) * 2006-02-16 2007-08-23 Saltigo Gmbh Formulation de gel servant à lutter contre les arthropodes et les plathelminthes

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002002087A2 (fr) * 2000-07-06 2002-01-10 Bayer Aktiengesellschaft Produits anthelminthiques permettant de prevenir les infections parasitaires chez l'homme et l'animal ii
US6562841B1 (en) * 2000-10-19 2003-05-13 The United States Of America As Represented By The Secretary Of Agriculture Methods and compositions for repelling arthropods
WO2003020232A2 (fr) * 2001-08-29 2003-03-13 Beiersdorf Ag Stabilisation de preparations cosmetiques ou dermatologiques contenant des substances actives repulsives
WO2005002537A2 (fr) * 2003-07-01 2005-01-13 Hygieia Healthcare Limited Perfectionnements apportes a une matiere organique ou concernant celle-ci
EP1738745A1 (fr) * 2005-06-27 2007-01-03 Beiersdorf AG Emulsion insectifuge
EP1762221A1 (fr) * 2005-07-20 2007-03-14 Beiersdorf AG Insectifuge à longue durée
WO2007079822A1 (fr) * 2005-12-22 2007-07-19 Merck Patent Gmbh Melange d'agents insectifuges
WO2007093298A1 (fr) * 2006-02-16 2007-08-23 Saltigo Gmbh Formulation de gel servant à lutter contre les arthropodes et les plathelminthes

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2218328A1 (fr) * 2009-02-17 2010-08-18 Cognis IP Management GmbH Compositions agrochimiques à base d'huile avec une viscosité améliorée
WO2010094408A1 (fr) * 2009-02-17 2010-08-26 Cognis Ip Management Gmbh Compositions agrochimiques à base d'huile avec viscosité accrue
US8580287B2 (en) 2009-02-17 2013-11-12 Cognis Ip Management Gmbh Oil-based agrochemical compositions with increased viscosity
AU2010214873B2 (en) * 2009-02-17 2014-08-21 Cognis Ip Management Gmbh Oil-based agrochemical compositions with increased viscosity

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WO2007093295A3 (fr) 2007-12-21
DE102006007549A1 (de) 2007-08-30

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