WO2007085729A3 - Nouvelle methode de synthese de l,4-morpholine-2,5-diones - Google Patents
Nouvelle methode de synthese de l,4-morpholine-2,5-diones Download PDFInfo
- Publication number
- WO2007085729A3 WO2007085729A3 PCT/FR2007/000135 FR2007000135W WO2007085729A3 WO 2007085729 A3 WO2007085729 A3 WO 2007085729A3 FR 2007000135 W FR2007000135 W FR 2007000135W WO 2007085729 A3 WO2007085729 A3 WO 2007085729A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- diones
- morpholine
- synthesis
- novel method
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008551822A JP2009528982A (ja) | 2006-01-25 | 2007-01-24 | 1,4−モルホリン−2,5−ジオンの新規の合成方法 |
CA002640031A CA2640031A1 (fr) | 2006-01-25 | 2007-01-24 | Nouvelle methode de synthese de l,4-morpholine-2,5-diones |
US12/162,334 US20100036120A1 (en) | 2006-01-25 | 2007-01-24 | Novel method for synthesis of 1,4-morpholine-2,5-diones |
EP07730853A EP1981861A2 (fr) | 2006-01-25 | 2007-01-24 | Nouvelle methode de synthese de l,4-morpholine-2,5-diones |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0600662A FR2896502B1 (fr) | 2006-01-25 | 2006-01-25 | Nouvelle methode de synthese de 1,4-morpholine-2,5-diones |
FR06/00662 | 2006-01-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007085729A2 WO2007085729A2 (fr) | 2007-08-02 |
WO2007085729A3 true WO2007085729A3 (fr) | 2008-04-24 |
Family
ID=36636457
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR2007/000135 WO2007085729A2 (fr) | 2006-01-25 | 2007-01-24 | Nouvelle methode de synthese de l,4-morpholine-2,5-diones |
Country Status (8)
Country | Link |
---|---|
US (1) | US20100036120A1 (fr) |
EP (1) | EP1981861A2 (fr) |
JP (1) | JP2009528982A (fr) |
CN (1) | CN101374822A (fr) |
CA (1) | CA2640031A1 (fr) |
FR (1) | FR2896502B1 (fr) |
RU (1) | RU2008134461A (fr) |
WO (1) | WO2007085729A2 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103012238A (zh) * | 2013-01-11 | 2013-04-03 | 华东理工大学 | 一种n-取代-1h-吡咯的制备方法 |
US20220354783A1 (en) | 2018-08-01 | 2022-11-10 | Edix-O Sarl | Injectable prolonged-action compositions for use in the treatment of nail disease and/or for promoting nail growth |
EP3603650A1 (fr) | 2018-08-01 | 2020-02-05 | Edix O Sarl | Compositions injectables et a duree d'action prolongee pour leur utilisation dans le traitement de maladies de l'ongle et/ou pour accelerer la croissance de l'ongle |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3392169A (en) * | 1965-09-02 | 1968-07-09 | Monsanto Co | 3, 6-dioxo-2-morpholine acetic acids and process for making them |
DE4440193A1 (de) * | 1994-11-10 | 1996-05-15 | Bayer Ag | Verwendung von Dioxomorpholinen zur Bekämpfung von Endoparasiten, neue Dioxomorpholine und Verfahren zur ihrer Herstellung |
WO1996040202A1 (fr) * | 1995-06-07 | 1996-12-19 | Chiron Corporation | Synthese d'oligomeres n-substitues |
-
2006
- 2006-01-25 FR FR0600662A patent/FR2896502B1/fr not_active Expired - Fee Related
-
2007
- 2007-01-24 EP EP07730853A patent/EP1981861A2/fr not_active Withdrawn
- 2007-01-24 US US12/162,334 patent/US20100036120A1/en not_active Abandoned
- 2007-01-24 WO PCT/FR2007/000135 patent/WO2007085729A2/fr active Application Filing
- 2007-01-24 CN CN200780003517.4A patent/CN101374822A/zh active Pending
- 2007-01-24 JP JP2008551822A patent/JP2009528982A/ja not_active Abandoned
- 2007-01-24 CA CA002640031A patent/CA2640031A1/fr not_active Abandoned
- 2007-01-24 RU RU2008134461/04A patent/RU2008134461A/ru not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3392169A (en) * | 1965-09-02 | 1968-07-09 | Monsanto Co | 3, 6-dioxo-2-morpholine acetic acids and process for making them |
DE4440193A1 (de) * | 1994-11-10 | 1996-05-15 | Bayer Ag | Verwendung von Dioxomorpholinen zur Bekämpfung von Endoparasiten, neue Dioxomorpholine und Verfahren zur ihrer Herstellung |
WO1996040202A1 (fr) * | 1995-06-07 | 1996-12-19 | Chiron Corporation | Synthese d'oligomeres n-substitues |
Non-Patent Citations (19)
Title |
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ARCELLI, ANTONIO ET AL: "Chiral 1,4-morpholine-2,5-dione derivatives as .alpha.-glucosidase inhibitors: Part 2", TETRAHEDRON: ASYMMETRY , 16(8), 1495-1501 CODEN: TASYE3; ISSN: 0957-4166, 2005, XP004842441 * |
ARCELLI, ANTONIO ET AL: "Chiral 1,4-morpholine-2,5-diones. Synthesis and evaluation as glucosidase inhibitors", MONATSHEFTE FUER CHEMIE , 135(8), 951-958 CODEN: MOCMB7; ISSN: 0026-9247, 2004, XP002469417 * |
CARLONI, ARMANDO ET AL: "Stereoselective synthesis of uncommon .alpha.',.alpha.'-dialkyl-.alpha.- amino acids. Part 1", TETRAHEDRON: ASYMMETRY , 9(17), 2987-2998 CODEN: TASYE3; ISSN: 0957-4166, 1998, XP004138976 * |
CINGOLANI G M ET AL: "Synthesis of l-(+)-3-(3-hydroxy-4-pivaloyloxybenzyl)-2,5-diketomorph oline as potential prodrug of l-dopa", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, vol. 10, no. 12, June 2000 (2000-06-01), pages 1385 - 1388, XP004207011, ISSN: 0960-894X * |
CRANE, SHELDON N. ET AL: "A Novel Enantioselective Synthetic Route to Omuralide Analogues with the Potential for Species Selectivity in Proteasome Inhibition", ORGANIC LETTERS , 3(9), 1395-1397 CODEN: ORLEF7; ISSN: 1523-7060, 2001, XP008038134 * |
DI FELICE, PINA ET AL: "A new stereoselective approach to .beta.-hydroxy-.alpha.-amino acids and dipeptides", TETRAHEDRON: ASYMMETRY , 10(11), 2191-2201 CODEN: TASYE3; ISSN: 0957-4166, 1999, XP004174102 * |
DIJKSTRA P J ET AL: "SYNTHETIC PATHWAYS TO POLYDEPSIPEPTIDES", MACROMOLECULAR SYMPOSIA, WILEY VCH VERLAG, WEINHEIM, DE, no. 153, March 2000 (2000-03-01), pages 67 - 76, XP000991927, ISSN: 1022-1360 * |
FENG, YAKAI ET AL: "Lipase-catalyzed ring-opening polymerization of 3(S)-sec-butylmorpholine- 2,5-dione", MACROMOLECULAR BIOSCIENCE , 1(2), 66-74 PUBLISHED IN: MACROMOL. CHEM. PHYS., 202(5) CODEN: MBAIBU; ISSN: 1616-5187, 2001, XP002396670 * |
GERONA-NAVARRO, GUILLERMO ET AL: "Entry to New Conformationally Constrained Amino Acids. First Synthesis of 3-Unsubstituted 4-Alkyl-4-carboxy-2-azetidinone Derivatives via an Intramolecular N.alpha.-C.alpha.-Cyclization Strategy", JOURNAL OF ORGANIC CHEMISTRY , 66(10), 3538-3547 CODEN: JOCEAH; ISSN: 0022-3263, 2001, XP002469416 * |
GRAZIANI, LUCIA ET AL: "An improved procedure for the enantioselective synthesis of (+)- and (-)-cis-4-hydroxyprolines and bulgecinines", TETRAHEDRON: ASYMMETRY , 7(5), 1341-1346 CODEN: TASYE3; ISSN: 0957-4166, 1996, XP004047693 * |
HUANG, XUEFEI ET AL: "Absolute Configurational Assignments of Secondary Amines by CD-Sensitive Dimeric Zinc Porphyrin Host", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , 124(35), 10320-10335 CODEN: JACSAT; ISSN: 0002-7863, 2002, XP002396669 * |
IN'T VELD P J A ET AL: "SYNTHESIS OF BIODEGRADABLE POLYESTERAMIDES WITH PENDANT FUNCTIONAL GROUPS", MAKROMOLEKULARE CHEMIE, MACROMOLECULAR CHEMISTRY AND PHYSICS, HUTHIG UND WEPF VERLAG, BASEL, CH, vol. 193, no. 11, 1 November 1992 (1992-11-01), pages 2713 - 2730, XP000311432, ISSN: 0025-116X * |
KOCH, CLAUS-JURGEN ET AL: "Asymmetric synthesis with 6-tert-butyl-5-methoxy-6-methyl-3,6-dihydro-2H- 1,4-oxazin-2-one as a new chiral glycine equivalent: preparation of enantiomerically pure .alpha.-tertiary and .alpha.-quaternary .alpha.-amino acids", EUROPEAN JOURNAL OF ORGANIC CHEMISTRY , (7), 1244-1263 CODEN: EJOCFK; ISSN: 1434-193X, 2003, XP002396668 * |
L.A. PAQUETTE, S. BRAND AND C. BEHRENS: "an enantioselective ring expansion route leading to furanose and pyranose nucleosides featuring spirodiketopiperazines at anomeric position", JOURNAL OF ORGANIC CHEMISTRY, vol. 64, no. 6, 1999, pages 2010 - 2025, XP002396695 * |
PORZI, GIANNI ET AL: "A new stereoselective synthesis of sterically constrained uncommon .alpha.,.alpha.'-dialkylated .alpha.-amino acids. Part 2", TETRAHEDRON: ASYMMETRY , 9(19), 3411-3420 CODEN: TASYE3; ISSN: 0957-4166, 1998, XP004339196 * |
PORZI, GIANNI ET AL: "Enantioselective synthesis of (R)- and (S)-.alpha.-amino acids using (6S)- and (6R)-6-methyl-morpholine-2,5-dione derivatives", TETRAHEDRON: ASYMMETRY , 7(1), 189-96 CODEN: TASYE3; ISSN: 0957-4166, 1996, XP004047913 * |
SHIRAHAMA H ET AL: "SYNTHESIS AND BIODEGRADABILITY OF DEPSIPEPTIDE COPOLYMERS - EFFECT OF AMINO ACID UNIT", KOBUNSHI RONBUNSHU (JAPANESE POLYMER SCIENCE AND TECHNOLOGY), SOCIETY OF POLYMER SCIENCE, TOKYO, JP, vol. 55, no. 6, 1 June 1998 (1998-06-01), pages 359 - 366, XP000779572, ISSN: 0386-2186 * |
SHIRAHAMA H ET AL: "SYNTHESIS AND BIODEGRADATION OF CYCLIC DEPSIPEPTIDE/EPSILON- CAPROLACTONE COPOLYMERS - EFFECT OF HYDROXY ACID UNIT -", KOBUNSHI RONBUNSHU (JAPANESE POLYMER SCIENCE AND TECHNOLOGY), SOCIETY OF POLYMER SCIENCE, TOKYO, JP, vol. 56, no. 2, February 1999 (1999-02-01), pages 77 - 85, XP000804328, ISSN: 0386-2186 * |
WEE ET AL: "Dirhodium tetraacetate catalyzed carbon-hydrogen insertion reaction in N-substituted.alpha.-carbomethoxy-.alpha.-diazoacetanilides and structural analogs. Substituent and conformational effects", JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 57, no. 16, 1992, pages 4404 - 4414, XP002177360, ISSN: 0022-3263 * |
Also Published As
Publication number | Publication date |
---|---|
WO2007085729A2 (fr) | 2007-08-02 |
FR2896502B1 (fr) | 2010-09-24 |
FR2896502A1 (fr) | 2007-07-27 |
JP2009528982A (ja) | 2009-08-13 |
US20100036120A1 (en) | 2010-02-11 |
EP1981861A2 (fr) | 2008-10-22 |
RU2008134461A (ru) | 2010-02-27 |
CA2640031A1 (fr) | 2007-08-02 |
CN101374822A (zh) | 2009-02-25 |
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