WO2007075572A3 - Inhibiteurs a base de purine oralement actifs de la proteine de choc thermique 90 - Google Patents
Inhibiteurs a base de purine oralement actifs de la proteine de choc thermique 90 Download PDFInfo
- Publication number
- WO2007075572A3 WO2007075572A3 PCT/US2006/048250 US2006048250W WO2007075572A3 WO 2007075572 A3 WO2007075572 A3 WO 2007075572A3 US 2006048250 W US2006048250 W US 2006048250W WO 2007075572 A3 WO2007075572 A3 WO 2007075572A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- heat shock
- shock protein
- orally active
- based inhibitors
- hsp90
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/36—Sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002634723A CA2634723A1 (fr) | 2005-12-22 | 2006-12-18 | Inhibiteurs a base de purine oralement actifs de la proteine de choc thermique 90 |
EP06845721A EP1962863A4 (fr) | 2005-12-22 | 2006-12-18 | Inhibiteurs a base de purine oralement actifs de la proteine de choc thermique 90 |
AU2006331917A AU2006331917A1 (en) | 2005-12-22 | 2006-12-18 | Orally active purine-based inhibitors of heat shock protein 90 |
JP2008547398A JP2009521446A (ja) | 2005-12-22 | 2006-12-18 | 熱ショックタンパク質90の経口活性なプリンベースの阻害剤 |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75363605P | 2005-12-22 | 2005-12-22 | |
US75344805P | 2005-12-22 | 2005-12-22 | |
US75369805P | 2005-12-22 | 2005-12-22 | |
US60/753,448 | 2005-12-22 | ||
US60/753,636 | 2005-12-22 | ||
US60/753,698 | 2005-12-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007075572A2 WO2007075572A2 (fr) | 2007-07-05 |
WO2007075572A3 true WO2007075572A3 (fr) | 2009-05-07 |
Family
ID=38218505
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/048250 WO2007075572A2 (fr) | 2005-12-22 | 2006-12-18 | Inhibiteurs a base de purine oralement actifs de la proteine de choc thermique 90 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1962863A4 (fr) |
JP (1) | JP2009521446A (fr) |
AU (1) | AU2006331917A1 (fr) |
CA (1) | CA2634723A1 (fr) |
WO (1) | WO2007075572A2 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2652263A1 (fr) * | 2006-05-12 | 2007-11-22 | Myriad Genetics, Inc. | Composes therapeutiques et leur utilisation contre le cancer |
US8324240B2 (en) * | 2007-03-20 | 2012-12-04 | Curis, Inc. | Fused amino pyridine as HSP90 inhibitors |
WO2009065035A1 (fr) * | 2007-11-14 | 2009-05-22 | Myriad Genetics, Inc. | Composés thérapeutiques et leur utilisation dans le traitement de maladies et de troubles |
EP2387316A4 (fr) | 2009-01-16 | 2012-06-13 | Curis Inc | Aminopyridines fusionnées pour le traitement de tumeurs cérébrales |
US9346808B2 (en) | 2011-04-05 | 2016-05-24 | Sloan-Kettering Institute For Cancer Research | Hsp90 inhibitors |
KR101984480B1 (ko) | 2011-04-05 | 2019-05-31 | 슬로안-케테링인스티튜트퍼캔서리서치 | Hsp90 억제제 |
CA2885259A1 (fr) | 2012-10-04 | 2014-04-10 | Pfizer Limited | Inhibiteurs de kinase associee a la tropomyosine pyrrolo[3,2-c]pyridine |
MX370664B (es) | 2013-08-16 | 2019-12-19 | Memorial Sloan Kettering Cancer Center | Inhibidores de la proteína regulada por glucosa 94 (gpr94) selectivos y usos de los mismos. |
CN109721499A (zh) * | 2018-12-19 | 2019-05-07 | 南京杰科丰环保技术装备研究院有限公司 | 一种硝基甲苯加氢制备甲基苯胺的制备方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4971972A (en) * | 1989-03-23 | 1990-11-20 | Schering Corporation | Phosphodiesterase inhibitors having an optionally substituted purine derivative portion and a benzo- or cyclopenta-furan portion |
US20040092520A1 (en) * | 2002-10-28 | 2004-05-13 | Pfizer Inc. | Purine compounds and uses thereof |
US20050113340A1 (en) * | 2003-09-18 | 2005-05-26 | Conforma Therapeutics Corporation | 2-Aminopurine analogs having HSP90-inhibiting activity |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2426952C (fr) * | 2000-11-02 | 2012-06-26 | Sloan-Kettering Institute For Cancer Research | Compositions renfermant des petites molecules destinees a se lier a hsp90 |
EP2336133A1 (fr) * | 2001-10-30 | 2011-06-22 | Conforma Therapeutics Corporation | Analogues de purine présentant une activité inhibitrice de HSP90 |
US7834181B2 (en) * | 2005-02-01 | 2010-11-16 | Slaon-Kettering Institute For Cancer Research | Small-molecule Hsp90 inhibitors |
-
2006
- 2006-12-18 EP EP06845721A patent/EP1962863A4/fr not_active Withdrawn
- 2006-12-18 AU AU2006331917A patent/AU2006331917A1/en not_active Abandoned
- 2006-12-18 JP JP2008547398A patent/JP2009521446A/ja not_active Withdrawn
- 2006-12-18 CA CA002634723A patent/CA2634723A1/fr not_active Abandoned
- 2006-12-18 WO PCT/US2006/048250 patent/WO2007075572A2/fr active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4971972A (en) * | 1989-03-23 | 1990-11-20 | Schering Corporation | Phosphodiesterase inhibitors having an optionally substituted purine derivative portion and a benzo- or cyclopenta-furan portion |
US20040092520A1 (en) * | 2002-10-28 | 2004-05-13 | Pfizer Inc. | Purine compounds and uses thereof |
US20050113340A1 (en) * | 2003-09-18 | 2005-05-26 | Conforma Therapeutics Corporation | 2-Aminopurine analogs having HSP90-inhibiting activity |
Non-Patent Citations (1)
Title |
---|
See also references of EP1962863A4 * |
Also Published As
Publication number | Publication date |
---|---|
AU2006331917A1 (en) | 2007-07-05 |
JP2009521446A (ja) | 2009-06-04 |
WO2007075572A2 (fr) | 2007-07-05 |
CA2634723A1 (fr) | 2007-07-05 |
EP1962863A4 (fr) | 2010-11-24 |
EP1962863A2 (fr) | 2008-09-03 |
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