WO2007068707A2

WO2007068707A2 - Sunscreen agent comprising merocyanines and triazines

Info

Publication number: WO2007068707A2
Application number: PCT/EP2006/069627
Authority: WO
Inventors: Heike Lerg; Claudia Mundt; Kerstin Skubsch; Christoph Smuda; Mirko Tesch
Original assignee: Beiersdorf Ag
Priority date: 2005-12-13
Filing date: 2006-12-13
Publication date: 2007-06-21
Also published as: EP1965870A2; WO2007068707A3; DE102005059739A1

Abstract

The invention relates to a cosmetic preparation containing a) one or several merocyanines, b) one or several triazines.

Description

Beiersdorf Aktiengesellschaft Hamburg

description

Sunscreens containing merocyanines and triazines

The present invention relates to sunscreens containing merocyanines and triazines.

The trend away from sophisticated paleness to "healthy, sporty brown skin" has been unbroken for years, and people are exposing their skin to sunlight, as it causes pigmentation in the sense of melanin formation, which has ultraviolet radiation from sunlight In addition to the acute injury (sunburn), long-term damage such as an increased risk of developing skin cancer due to excessive exposure to light from the UVB range (wavelength: 280-320 nm) occurs UVB and UVA radiation (wavelength: 320-400 nm) also leads to a weakening of the elastic and collagen fibers of the connective tissue, which leads to numerous phototoxic and photoallergic reactions and leads to premature aging of the skin.

To protect the skin, therefore, a number of sunscreen filter substances have been developed which can be used in cosmetic preparations. These UVA and UVB filters are summarized in most industrialized countries in the form of positive lists such as Appendix 7 of the Cosmetics Regulation.

However, the large number of commercially available sunscreen products must not hide the fact that these prior art preparations have a number of disadvantages:

^■ The incorporation in particular of larger amounts of UV filter substances, the combination of the filters with each other and with other components is usually limited for stability reasons.

^■ The preparations do not show a balanced UV absorption spectrum. The photoprotective filter performance in the UVA range, in particular in the UVA1 range (from 340 to

400 nm) and the UV-A balance (according to DIN 67502) is deficient. ^■ A range of UV photoprotective filters, such as butylmethoxydibenzoylmethane, are photolabile and must be stabilized frequently with other UV photoprotective filters, such as p-methylbenzylidene camphor, whose medical compatibility is not uncontroversial. ^■ The removal from storage containers made of plastic (in particular polyethylene,

Polypropylene, polyethylene terephthalate) is not easily possible. In particular, the "complete" emptying of the storage vessels is difficult.

It was therefore the object of the present invention to overcome the deficiencies of the prior art and to develop cosmetic preparations in which

^{■ increases} the incorporation of, in particular, larger quantities of UV filter substances, and the combination of the filters with one another and with other constituents is made easier for reasons of stability,

^■ the preparations show a balanced UV absorption spectrum, ^■ the sunscreen filter performance is increased in the UVA range, in particular in the UVA1 range (from 340 to 400 nm),

^■ the UV-A balance (according to DIN 67502) is higher than 30,

^■ the preparations themselves are photostable,

^■ the preparations photolabile UV-filters, for example, butyl methoxydibenzoylmethane, which may contain, it being possible to dispense with the use of p-methylbenzylidenecamphor,

^■ The removal of storage containers made of plastic (especially polyethylene, polypropylene, Polyehtylenterephthalat) is facilitated, in particular, the "complete" emptying of the storage vessels should be simplified.

Surprisingly, the objects are achieved by a cosmetic preparation comprising a) one or more merocyanines, b) one or more triazines.

Although WO 2004/006878 discloses cosmetic preparations with merocyanines, this document could not point the way to the present invention.

According to the invention, the preparation according to the invention is advantageously characterized in that the preparation contains merocyanines in a total concentration of 0.1 to 20% by weight and preferably of 0.5 to 10% by weight, based on the total weight of the preparation. Furthermore, according to the invention, the cosmetic preparation according to the invention is advantageously characterized in that the preparation contains triazines in a total concentration of 0.1 to 30% by weight and preferably in a total concentration of 0.5 to 15% by weight, based on the total weight of the preparation ,

Embodiments of the present invention which are advantageous according to the invention are characterized in that the weight ratio of merocyanines to triazines is from 1:20 to 20: 1 and preferably from 1:10 to 10: 1.

It is preferred for the purposes of the present invention if one or more of the following compounds is used as merocyanines:

Connection 1

Compound 2 Compound 3

In a preferred embodiment of the present invention, the following compound is used as merocyanine:

Connection 1

In this case, the preparation according to the invention contains this merocyanine in a concentration of 0.1 to 20% by weight and preferably in a concentration of 0.5 to 10% by weight, based on the total weight of the preparation.

In another preferred embodiment according to the invention, the following compound is used as merocyanine:

Connection 2

Embodiments of the present invention which are advantageous according to the invention are characterized in that the triazines used are one or more compounds selected from the group of the compounds 2,4-bis - {[4- (2-ethylhexyloxy) -2-hydroxy] -phenyl} -6 - (4-methoxyphenyl) -1, 3,5-triazine (INChBis-ethylhexyloxyphenol methoxyphenyl triazine); Dioctylbutylamidotriazone (INCI:

Diethylhexyl-Butamidotriazone); 2,4-bis- [5-1 (dimethylpropyl) benzoxazol-2-yl- (4-phenyl) -imino] -

6- (2-ethylhexyl) -imino-1,3,5-triazine with (CAS No. 288254-16-0); 4,4 ', 4 "- (1,3,5-triazine-2,4,6-triyltriimino) -tris-benzoic acid tris (2-ethylhexyl ester) (also: 2,4,6-tris [anilino] (p-carbo-2'-ethyl-

1'-hexyloxy)] - 1, 3,5-triazine (INCI: ethylhexyl triazone); 2,4,6-Tribiphenyl-4-yl-1,3,5-triazine can be used. It is preferred according to the invention if the following triazines are used in the preparation according to the invention: 2,4-bis - {[4- (2-ethyl-hexyloxy) -2-hydroxy] -phenyl} -6- (4-methoxyphenyl) - 1, 3,5-triazine (INCkBis-ethylhexyloxyphenol methoxyphenyl triazine); 4,4 ', 4 "- (1,3,5-triazine-2,4,6-triyltriimino) tris-benzoic acid tris (2-ethylhexyl ester) (also: 2,4,6-tris [anilino] (p-carbo-2'-ethyl-1'-hexyloxy)] - 1, 3,5-triazine (INCI: ethylhexyl triazone).

Preferred embodiments of the present invention are characterized in that the preparation comprises one or more further UV filters selected from the group of the compounds phenylene-1,4-bis (2-benzimidazyl) -3,3'-5,5'-tetrasulfonic acid salts ; 2-phenylbenzimidazole-5-sulfonic acid salts; 1,4-di (2-oxo-10-sulfo-3-bomylidenemethyl) benzene and its salts; 4- (2-oxo-3-bornylidenemethyl) benzenesulfonic acid; 2-methyl-5- (2-oxo-3-bornylidenemethyl) sulfonic acid salts; 2,2'-methylenebis (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) -phenol); 2- (2H-Benzotriazol-2-yl) -4-methyl-6- [2-methyl-3- [1,3,3,3-tetramethyl-1 - [(trimethylsilyl) oxy] disiloxanyl] propyl] -phenol; 3- (4-methylbenzylidene) camphor; 3-benzylidene-camphor; ethylhexyl salicylate; Terephthalidendicamphersulfonsäure; 2-ethylhexyl 4- (dimethylamino) benzoate; 4- (dimethylamino) benzoic acid amyl ester; 4

Methoxybenzalmalon-säuredi (2-ethylhexyl) ester; 4-methoxycinnamate (2-ethylhexyl) ester; 4-methoxycinnamic acid isoamyl ester; 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone; 2,2'-dihydroxy-4-methoxybenzophenone; Hexyl 2- (4'-diethylamino-2'-hydroxybenzoyl) benzoate 4- (tert-butyl) -4'-methoxydibenzoylmethane;

homomenthyl; 2-ethylhexyl 2-hydroxybenzoate; 2-ethylhexyl-2-cyano-3,3-diphenylacrylate; dimethicodiethylbenzalmalonate; 3- (4- (2,2-ethoxycarbonylvinyl) phenoxy) propenyl) methoxysiloxane / dimethylsiloxane copolymer; titanium dioxide; Zinc oxide in a concentration of 0.01 to 40% by weight and preferably in a concentration of 1 to 20% by weight, based on the total weight of the preparation.

The pigments (titanium dioxide, zinc oxide) can advantageously also be used in the form of commercially available oily or aqueous predispersions for the purposes of the present invention. Advantageously, dispersants and / or solubilizers can be added to these predispersions.

According to the invention, the pigments (titanium dioxide, zinc oxide) can advantageously be surface-treated ("coated"), in which case for example a hydrophilic, amphiphilic or hydrophobic character is to be formed or is to be retained.This surface treatment can consist in that the pigments are prepared by processes known per se with a thin hydrophilic and / or hydrophobic inorganic and / or organic layer Various surface coatings may also contain water for the purposes of the present invention.

Inorganic surface coatings in the context of the present invention may consist of aluminum oxide (Al ₂ O ₃ ), aluminum hydroxide Al (OH) ₃ , or aluminum oxide hydrate (also: alumina, CAS No .: 1333-84-2), sodium hexametaphosphate (NaPO ₃ ) ₆ , sodium metaphosphate (NaPOs) _n , silica (SiO ₂ ) (also: silica, CAS No .: 7631-86-9), barium sulfate (BaSO ₄ ) or iron oxide (Fe ₂ O ₃ ). These inorganic surface coatings may occur alone, in combination and / or in combination with organic coating materials.

Organic surface coatings for the purposes of the present invention may consist of vegetable or animal aluminum stearate, vegetable or animal stearic acid, lauric acid, dimethylpolysiloxane (also: dimethicone), methylpolysiloxane (methicone), simethicone (a mixture of dimethylpolysiloxane with an average chain length of 200 to 350 Dimethylsiloxane units and silica gel) or alginic acid. These organic surface coatings may be present alone, in combination and / or in combination with inorganic coating materials.

According to the invention, the preparation according to the invention is free of p-methylbenzylidene camphor.

Advantageously in accordance with the invention, the preparation according to the invention is free from diethylhexyl naphthalate (Hallbrite TQ or Corapan TQ from Symrise).

According to the invention, the preparation according to the invention is present in the form of an emulsion. The following two embodiments have proven to be preferred according to the invention:

On the one hand, it is advantageous according to the invention if the preparation is in the form of an O / W emulsion. In this case, it is particularly preferred according to the invention if the preparation comprises one or more O / W emulsifiers selected from the group of the compounds glyceryl stearate citrate, glyceryl stearate (self-emulsifying), stearic acid, stearate salts, polyglyceryl-3-methylglycose distearate, ceteareth-20, PEG-40 Stearate and sodium Cetearylsulfat contains. These O / W emulsifiers according to the invention may advantageously be present in a concentration of 0.1 to 10% by weight and preferably in a concentration of 0.2 to 7% by weight, based on the total weight of the preparation in this.

On the other hand, it is advantageous according to the invention if the preparation is in the form of a W / O emulsion. In this case, it is particularly preferred according to the invention if the preparation contains one or more W / O emulsifiers selected from the group of the compounds polyglyceryl-2-dipolyhydroxystearate, PEG-30 dipolyhydroxystearate, cetyl dimethicone copolyol, polyglyceryl-3 diisostearate.

According to the invention, these W / O emulsifiers according to the invention may advantageously be present in a concentration of from 0.1 to 10% by weight and preferably in a concentration of from 0.2 to 7% by weight, based on the total weight of the preparation.

The preparations according to the invention may also advantageously contain self-tanning substances, for example dihydroxyactone and / or melanin derivatives in concentrations of 1% by weight up to 10% by weight, based on the total weight of the preparation.

Furthermore, the preparations according to the invention may also advantageously contain repellents for protection against mosquitoes, ticks and spiders and the like. Advantageous z. N, N-diethyl-3-methylbenzamide (trade name: Meta-delphene, "DEET"), dimethyl phthalate (trade name: Palatinol M, DMP), 1-piperidinecarboxylic acid 2- (2-hydroxyethyl) -1-methylpropyl ester, and especially 3- (Nn-butyl-N-acetyl-amino) -propionic acid ethyl ester (available commercially from Merck under the tradename Insekt Repellent® 3535.) The repellents can be used either singly or in combination.

Moisturizers are substances or mixtures of substances which give cosmetic preparations the property, after application or spreading on the skin surface, to reduce the moisture release of the horny layer (also called transepidermal water joss (TEWL)) and / or hydration of the horny layer positively influence.

Advantageous humectants (moisturizers) for the purposes of the present invention are, for example, glycerol, lactic acid and / or lactates, in particular sodium lactate,

Butylene Glycol, Propylene Glycol, Biosaccaride Gum-1, Glycine Soy, Ethylhexyloxyglycerol,

Pyrrolidonecarboxylic acid, hydroxyethyl urea and urea. Furthermore, it is in particular of Advantage of using polymeric moisturizers from the group of water-soluble and / or water-swellable and / or water-gellable polysaccharides. Hyaluronic acid, chitosan and / or a fucose-rich polysaccharide, for example, which are filed in the Chemical Abstracts under the registry number 178463-23-5 and z. B. under the name Fucogel®1000 of the company SOLABIA SA is available. Moisturizers can also be used advantageously as anti-wrinkle active ingredients for protection against skin changes, as described, for example, in US Pat. B. occur during skin aging, can be used.

It is advantageous for the purposes of the present invention, when the inventive preparation one or more humectants in a total concentration of 0.1 to 20% by weight and preferably in a total concentration of 0.5 to 10% by weight, each based on the total weight of Preparation containing.

The cosmetic preparations according to the invention may also advantageously, although not necessarily, contain fillers which are e.g. B. the sensory and cosmetic

Further improve the properties of the formulations and, for example, cause or enhance a velvety or silky feel on the skin. Advantageous fillers for the purposes of the present invention are starch and starch derivatives (such as, for example, tapioca starch,

Distarch phosphate, aluminum or sodium starch octenylsuccinate and the like), pigments which have neither primarily a UV filter effect nor a coloring effect (such as. For example, boron nitride etc.) and / or Aerosils ^® (CAS-No. 7631-86 -9) and / or talc.

The aqueous phase of the preparations according to the invention may advantageously comprise customary cosmetic auxiliaries, for example alcohols, in particular those of low C number, preferably ethanol and / or isopropanol, diols or polyols of low C number and their ethers, preferably propylene glycol, 2-methylpropane-1, 3-diol, glycerol, ethylene glycol, ethylene glycol monoethyl or monobutyl ether, propylene glycol monomethyl, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ether and analogous products, polymers, foam stabilizers, electrolytes, self-tanning agents and in particular one or more thickeners, which or which can be advantageously selected from the group of silica, aluminum silicates, polysaccharides or their derivatives, for. As hyaluronic acid, xanthan gum, hydroxypropylmethylcellulose, particularly advantageous from the group of polyacrylates, preferably a polyacrylate from the group of so-called carbopols, for example Carbopols types 980, 981, 1382, 2984, 5984, each individually or in combination nation. Further thickeners advantageous according to the invention are permuents TR 1, TR 2, Aristoflex AVC. According to the invention, the preparations according to the invention advantageously contain one or more film formers. Film formers for the purposes of the present invention are substances of different composition, which are characterized by the following property: If a film former is dissolved in water or other suitable solvents and the solution is then applied to the skin, it forms a film after the solvent has evaporated which essentially has a protective function.

It is particularly advantageous to use the film formers from the group of polymers based on polyvinylpyrrolidone (PVP).

to choose. Particularly preferred are copolymers of polyvinylpyrrolidone, for example the PVP hexadecene copolymer and the PVP eicosene copolymer, which are available under the trade names Antaron V216 and Antaron V220 in the GAF Chemicals Cooperation.

Also advantageous are other polymeric film formers, such as sodium polystyrene sulfonate, sold under the tradename Flexan 130 at National Starch and Chemical Corp. and / or polyisobutene, available from Rewo under the tradename Rewopal PIB1000. Other suitable polymers are e.g. Polyacrylamides (Seppigel 305), polyvinyl alcohols, PVP, PVP / VA copolymers, polyglycols. Also advantageous is the use of hydrogenated castor oil dimerdilinoleate (CAS 646054-62-8, INCI Hydrogenated Castor OiI Dimer Dilinoleate), which can be purchased from Kokyu Alcohol Kogyo under the name Risocast DA-H or PPG-3 Benzylethermyristat ( CAS 403517-45-3), which can be obtained under the trade name Crodamol STS from Croda Chemicals.

The oil phase of the preparation according to the invention is advantageously selected from the group of polar oils, for example from the group of lecithins and fatty acid triglycerides, namely the triglycerol esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of 8 to 24, in particular 12 to 18 carbon atoms. The fatty acid triglycerides can be selected, for example, advantageously from the group of synthetic, semi-synthetic and natural oils, such as. Cocoglyceride, olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, castor oil, wheat germ oil, grapeseed oil, thistle oil, evening primrose oil, macadamia nut oil and the like. Also advantageous according to the invention are z. As natural waxes of animal and vegetable origin, such as beeswax and other insect waxes and berry wax, shea butter and / or lanolin (wool wax).

In the context of the present invention, further advantageous polar oil components can furthermore be selected from the group of esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of 3 to 30 carbon atoms and saturated and / or unsaturated, branched and / or or unbranched alcohols of a chain length of 3 to 30 carbon atoms and from the group of esters of aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols having a chain length of 3 to 30 carbon atoms. Such ester oils can then advantageously be selected from the group consisting of phenylethyl benzoate, octyl palmitate, octyl cocoate, octyl isostearate, octyldodeceyl myristate, octyldodecanol, cetearyl isononanoate, isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n-butyl stearate, n-hexyl laurate, n-decyl oleate, isooctyl stearate, isononyl stearate, Isononyl isononanoate, 2-ethylhexyl palmitate, 2-ethylhexyl laurate, 2-hexyldecyl stearate, 2-octyl dodecyl palmitate, stearyl heptanoate, isopropyl lauroyl sarcosinate, oleyl oleate, oleyl erucate, erucyl oleate, erucyl erucate, tridecyl stearate, tridecyl trimellitate, as well as synthetic, semi-synthetic and natural mixtures of such esters, e.g. , B. jojoba oil.

Furthermore, the oil phase can be advantageously selected from the group of dialkyl ethers and dialkyl carbonates, advantageous z. B. dicaprylyl ether (Cetiol OE) and / or dicaprylyl, for example, that available under the trade name Cetiol CC in the company. Cognis.

It is further preferred that the oil component or components from the group Isoeikosan, Neopentylglykoldiheptanoat, Propylenglykoldicaprylat / dicaprate, caprylic / capric / diglycerylsuccinate, butylene glycol dicaprylate / dicaprate, Ci ₂ -i ₃ -alkyllactate, di-Ci ₂ -i ₃ -Alkyltartrat , Triisostearin, dipentaerythrityl hexacaprylate / hexacaprate, propylene glycol monoisostearate, tricaprylin, dimethylisorboride. It is particularly advantageous if the oil phase of the formulation according to the invention has a content of stanchions Ci ₂ has -is-alkyl benzoate, or consists entirely of this.

Advantageous oil components are also z. Butyloctyl salicylate (for example that available under the trade name Hallbrite BHB from the company CP Hall), hexadecyl benzoate and butyloctyl benzoate and mixtures thereof (Hallstar AB).

Any mixtures of such oil and wax components are also advantageous to use in the context of the present invention. Furthermore, the oil phase can also advantageously contain non-polar oils, for example those which are selected from the group of branched and unbranched hydrocarbons and waxes, in particular mineral oil, Vaseline (petrolatum), paraffin oil, squalane and squalene, polyolefins, hydrogenated polyisobutenes, C13- 16 isoparaffin and isohexadecane. Among the polyolefins, polydecenes are the preferred substances.

The preparations according to the invention can furthermore advantageously contain one or more substances from the following group of siloxane elastomers, for example in order to increase the water resistance and / or the sun protection factor of the products: (a) siloxane elastomers which contain the units R ₂ SiO and RSiOi ₅ and / or R ₃ SiO ₀ S and / or SiO ₂ , wherein the individual radicals R are each independently hydrogen, Ci _-24- alkyl (such as methyl, ethyl, propyl) or aryl (such as phenyl or ToIyI), alkenyl (such as vinyl ) and the weight ratio of the units R ₂ SiO to RSiOi _{5 is selected} from the range of 1: 1 to 30: 1;

(b) Siloxane elastomers which are insoluble and swellable in silicone oil obtainable by the addition reaction of an organopolysiloxane (1) containing silicon-bonded hydrogen with an organopolysiloxane (2) containing unsaturated aliphatic groups, the proportions used being such be such that the amount of hydrogen of the organopolysiloxane (1) or the unsaturated aliphatic groups of the organopolysiloxane (2)

In the range of 1 to 20 mol%, if the organopolysiloxane is not cyclic and

In the range of 1 to 50 mol%, when the organopolysiloxane is cyclic.

Advantageously in the context of the present invention, the siloxane elastomer (s) are in the form of spherical powders or in the form of gels.

Advantageously present in the form of spherical powders siloxane elastomers are those with the INCI name dimethicone / vinyl dimethicone crosspolymer, for example that available from DOW CORNING under the trade names DOW CORNING 9506 Powder available.

It is particularly preferred if the siloxane elastomer is used in combination with oils of hydrocarbons of animal and / or vegetable origin, synthetic oils, synthetic esters, synthetic ethers or mixtures thereof. Particularly advantageous preparations are also obtained when antioxidants are used as additives or active ingredients. According to the invention, the preparations advantageously contain one or more antioxidants. As favorable, but nevertheless optional to be used antioxidants all suitable or common for cosmetic applications antioxidants can be used.

Particularly advantageous for the purposes of the present invention, water-soluble antioxidants can be used, such as vitamins, eg. As ascorbic acid and its derivatives.

Further preferred antioxidants are vitamin E and its derivatives as well as vitamin A and its derivatives.

The amount of the antioxidants (one or more compounds) in the preparations is preferably 0.001 to 30 wt .-%, particularly preferably 0.05 to 20 wt .-%, in particular 0.1 to 10 wt .-%, based on the total weight the preparation.

If vitamin E and / or its derivatives represent the antioxidant (s), it is advantageous to choose their respective concentrations from the range from 0.001 to 10% by weight, based on the total weight of the formulation.

If vitamin A or vitamin A derivatives, or carotenes or derivatives thereof, are the antioxidant (s), it is advantageous if their respective concentrations are in the range from 0.001 to 10% by weight, based on the total weight of the formulation choose.

It is particularly advantageous if the cosmetic preparations according to the present invention contain cosmetic active ingredients, where preferred active ingredients are antioxidants which can protect the skin against oxidative stress.

Further advantageous active ingredients in the context of the present invention are natural active ingredients and / or derivatives thereof, such as. Alpha-lipoic acid, folic acid, phytoene, D-biotin, coenzyme Q10, alpha-glucosylrutin, carnitine, carnosine, natural and / or synthetic isoflavonoids, creatine, creatinine, taurine and / or beta-alanine, and 8-hexadecene-1, 16-dicarboxylic acid (dioic acid, CAS number 20701-68-2, provisional INCI name octadecenedioic acid) and / or licochalcone A.

Inventive formulations which z. B. known anti-wrinkle agents such as flavone glycosides (especially α-glycosyl rutin), coenzyme Q10, vitamin E and / or derivatives and the like contain, are particularly advantageous for protection against aesthetically unattractive skin changes, as z. Skin aging (such as dryness, roughness, dryness wrinkles, itching, decreased refatting (eg, after washing), visible vascular dilation (telangiectasia, cuperosis), slackness and wrinkle and wrinkle formation, localized hypersensitivity). , Hypo and false pigmentation (eg, age spots), increased susceptibility to mechanical stress (eg, cracking and the like), and fatigued skin, Further advantageously, they are useful against the appearance of dry or rough skin.

The cosmetic preparations according to the invention may contain cosmetic adjuvants, such as are commonly used in such preparations, for. Preservatives, preservatives, complexing agents, bactericides, perfumes, substances for preventing or increasing foaming, dyes, pigments which have a coloring effect, thickeners, moisturizing and / or moisturizing substances, fillers which improve the feel on the skin, fats, oils, Waxes or other common ingredients of a cosmetic or dermatological formulation such as alcohols, polyols, polymers, foam stabilizers, electrolyte, organic solvents or silicone derivatives.

Also according to the invention is a plastic bottle containing the cosmetic preparation according to the invention. It is inventively preferred when used as plastic for the plastic bottle polyethylene, polypropylene or polyethylene terephthalate.

Advantageous in the context of the present invention are preparations for the care of the skin: they can serve the cosmetic sunscreen, as well as make-up product in decorative cosmetics.

According to their structure, cosmetic compositions according to the present invention may be used, for example, as a skin protection cream, day cream or night cream, etc. It may be possible and advantageous to use the compositions according to the invention as a basis for pharmaceutical formulations.

It is also advantageous in the context of the present invention to prepare cosmetic preparations whose main purpose is not the protection from sunlight, but which nevertheless contain a content of UV protective substances. So z. B. in day creams or makeup products usually incorporated UV-A or UV-B filter substances. Also, UV protectants, as well as antioxidants and, if desired, preservatives, an effective protection of the preparations themselves against spoilage. Also favorable are cosmetic preparations which are in the form of a sunscreen.

In particular, according to the invention, the use of the preparation according to the invention for protection against aging of the skin (in particular for protection against UV-related aging of the skin) and as a sunscreen agent.

According to the invention, the preparation according to the invention advantageously has a pH of 5 to 8. This can be adjusted by the conventional acids, bases and buffer systems.

According to the invention, the preparation according to the invention advantageously has a UV-A balance of greater than or equal to 30 (measured according to DIN 67502).

For use, the cosmetic preparations according to the invention in the for

Cosmetics usual way applied to the skin and / or hair in sufficient quantity.

Comparative test

The following comparative experiment illustrates the effect of reduced degradation of the merocyanine after irradiation. (Example of a formulation with less photostability).

Execution:

The emulsions were applied to roughened Plexiglas plates and recorded the absorption spectrum at λ> 290 nm to 400 nm before and after irradiation. The measuring procedure was carried out analogously to DIN Method 67502. Irradiation was by sun-simulated light (SSR light), the dose of which was determined with a UVA probe.

Examples

The following examples are intended to illustrate the present invention without limiting it. Unless indicated otherwise, all amounts, proportions and percentages are based on the weight and the total amount or on the total weight of the preparations.

1. Examples of W / O emulsions

2. Examples of cosmetic foams

3. Examples of O / W emulsions

Claims

claims:

1. Cosmetic preparation comprising a) one or more merocyanines, b) one or more triazines.

2. Cosmetic preparation according to claim 1, characterized in that the

Preparation Merocyanine in a total concentration of 0.1 to 20% by weight, based on the total weight of the preparation contains.

3. Cosmetic preparation according to one of the preceding claims, characterized in that the preparation contains triazines in a total concentration of 0.1 to 30% by weight, based on the total weight of the preparation.

4. Cosmetic preparation according to one of the preceding claims, characterized in that the weight ratio of merocyanines to triazines from 1: 20 to 20: 1.

5. Cosmetic preparation according to one of the preceding claims, characterized in that as merocyanines one or more of the following compounds is used:

6. Cosmetic preparation according to one of the preceding claims, characterized in that the following compound is used as merocyanine:

7. Cosmetic preparation according to one of the preceding claims, characterized in that the following compound is used as merocyanine:

8. Cosmetic preparation according to one of the preceding claims, characterized in that as triazines one or more compounds selected from the group of compounds 2,4-bis - {[4- (2-ethyl-hexyloxy) -2-hydroxy] -phenyl } -6- (4-methoxyphenyl) -1, 3,5-triazine (INCI:: bis-ethylhexyloxyphenol methoxyphenyl triazine);

Dioctylbutylamidotriazone (INCI: diethylhexyl-butamidotriazone); 2,4-bis- [5-1 (dimethylpropyl) benzoxazol-2-yl- (4-phenyl) -imino] -6- (2-ethylhexyl) -imino-1,3,5-triazine with the CAS No. 288254-16-0); 4,4 ', 4 "- (1,3,5-triazine-2,4,6-triyltriimino) tris-benzoic acid tris (2-ethylhexyl ester) (also: 2,4,6-tris [anilino] (p-carbo-2'-ethyl-1'-hexyloxy)] - 1, 3,5-triazine (INCI: ethylhexyl triazone); 2,4,6-tribiphenyl-4-yl-1,3,5-triazine ,

9. Cosmetic preparation according to one of the preceding claims, characterized in that the preparation one or more further UV filters selected from the group of compounds phenylene-1, 4-bis (2-benzimidazyl) -3,3'-5, 5'-tetrasulfonic acid salts; 2-phenylbenzimidazole-5-sulfonic acid salts; 1,4-di (2-oxo-10-sulfo-3-bomylidenemethyl) benzene and its salts; 4- (2-oxo-3-bomylidenemethyl) benzene sulfonic acid salts; 2-methyl-5- (2-oxo-3-bornylidenemethyl) sulfonic acid salts; 2,2'-methyl-bis (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) -phenol); 2- (2H-benzotriazol-2-yl) -4-methyl-6- [2-methyl-3- [1,3,3,3-tetramethyl-1 - [(trimethylsilyl) oxy] disiloxanyl] propyl] -phenol; 3- (4-methylbenzylidene) camphor; 3-benzylidenecamphor; ethylhexyl salicylate; Terephthalidendicamphersulfonsäure; 2-ethylhexyl 4- (dimethylamino) benzoate; 4- (dimethylamino) benzoic acid amyl ester; Di (2-ethylhexyl) -4-methoxybenzalmalonate; 2-ethylhexyl 4-methoxycinnamate; Isoamyl 4-methoxycinnamate; 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone;2,2'-dihydroxy-4-methoxybenzophenone; Hexyl 2- (4'-diethylamino-2'-hydroxybenzoyl) benzoate 4- (tert-butyl) -4'-methoxydibenzoylmethane;homomenthyl; 2-ethylhexyl 2-hydroxybenzoate; 2-ethylhexyl-2-cyano-3,3-diphenylacrylate; dimethicodiethylbenzalmalonate; 3- (4- (2,2-bisethoxycarbonylvinyl) phenoxy) propenyl) methoxysiloxane / dimethylsiloxane copolymer;

titanium dioxide; Contains zinc oxide in a concentration of 0.01 to 30% by weight, based on the total weight of the preparation.

10. Cosmetic preparation according to one of the preceding claims, characterized in that the preparation is in the form of an O / W emulsion.

1 1. A cosmetic preparation according to claim 10, characterized in that the

Preparation of one or more O / W emulsifiers selected from the group of compounds glyceryl stearate citrate, glyceryl stearate (self-emulsifying), stearic acid, stearate salts, polyglyceryl-3-methylglycose distearate, ceteareth-20, PEG-40 stearate, sodium cetearyl sulfate.

12. Cosmetic preparation according to one of the preceding claims, characterized in that the preparation is in the form of a W / O emulsion.

13. Cosmetic preparation according to claim 12, characterized in that the preparation contains one or more W / O emulsifiers selected from the group of the compounds polyglyceryl-2-dipolyhydroxystearate, PEG-30 dipolyhydroxystearate, cetyl dimethicone copolyol, polyglyceryl-3 diisostearate.

14. Plastic bottle containing a cosmetic preparation according to one of the preceding claims.

15. Plastic bottle according to claim 14, characterized in that are used as plastic polyethylene, polypropylene or polyethylene terephthalate.