WO2007064865A3 - Fabg polypeptides ( 3-oxoacyl- [ acyl-carrier protein ] reductase ) involved in bacterial fatty acid synthesis - Google Patents

Fabg polypeptides ( 3-oxoacyl- [ acyl-carrier protein ] reductase ) involved in bacterial fatty acid synthesis Download PDF

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Publication number
WO2007064865A3
WO2007064865A3 PCT/US2006/045969 US2006045969W WO2007064865A3 WO 2007064865 A3 WO2007064865 A3 WO 2007064865A3 US 2006045969 W US2006045969 W US 2006045969W WO 2007064865 A3 WO2007064865 A3 WO 2007064865A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
fabg
oxoacyl
reductase
acyl
Prior art date
Application number
PCT/US2006/045969
Other languages
French (fr)
Other versions
WO2007064865A2 (en
Inventor
Judd M Berman
Nachum Kaplan
Original Assignee
Affinium Pharm Inc
Judd M Berman
Nachum Kaplan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affinium Pharm Inc, Judd M Berman, Nachum Kaplan filed Critical Affinium Pharm Inc
Publication of WO2007064865A2 publication Critical patent/WO2007064865A2/en
Publication of WO2007064865A3 publication Critical patent/WO2007064865A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

The present invention relates to polypeptide targets for pathogenic bacteria. The invention also provides biochemical and biophysical characteristics of those polypeptides.
PCT/US2006/045969 2005-12-01 2006-12-01 Fabg polypeptides ( 3-oxoacyl- [ acyl-carrier protein ] reductase ) involved in bacterial fatty acid synthesis WO2007064865A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74206605P 2005-12-01 2005-12-01
US60/742,066 2005-12-01

Publications (2)

Publication Number Publication Date
WO2007064865A2 WO2007064865A2 (en) 2007-06-07
WO2007064865A3 true WO2007064865A3 (en) 2008-01-10

Family

ID=37998691

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/045969 WO2007064865A2 (en) 2005-12-01 2006-12-01 Fabg polypeptides ( 3-oxoacyl- [ acyl-carrier protein ] reductase ) involved in bacterial fatty acid synthesis

Country Status (1)

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WO (1) WO2007064865A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103678947B (en) * 2014-01-06 2017-02-22 上海微谱信息技术有限公司 Method and system for determining long chain organic compound structure by using carbon spectrum data
CN103728330B (en) * 2014-01-09 2016-06-01 上海微谱信息技术有限公司 Carbon-13 nmr spectra data are utilized to determine method and the system of organic compound structure
CN105954311A (en) * 2016-06-22 2016-09-21 四川好医生攀西药业有限责任公司 Method for constructing <1>H-NMR fingerprint spectra of Periplaneta americana and extract of Periplaneta americana

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023611A1 (en) * 1998-10-22 2000-04-27 Smithkline Beecham Corporation FabG
US20050026187A1 (en) * 2001-01-03 2005-02-03 Smithkline Beecham Corporation Methods of and compounds for modulating the activity of bacterial FabG

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023611A1 (en) * 1998-10-22 2000-04-27 Smithkline Beecham Corporation FabG
US20050026187A1 (en) * 2001-01-03 2005-02-03 Smithkline Beecham Corporation Methods of and compounds for modulating the activity of bacterial FabG

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE UniProt [online] 1 June 2003 (2003-06-01), "3-oxoacyl-(Acyl-carrier-protein) reductase.", XP002441977, retrieved from EBI accession no. UNIPROT:Q81JG6 Database accession no. Q81JG6 *
FARBER G K: "NEW APPROACHES TO RATIONAL DRUG DESIGN", PHARMACOLOGY AND THERAPEUTICS, ELSEVIER, GB, vol. 84, no. 3, December 1999 (1999-12-01), pages 327 - 332, XP001062868, ISSN: 0163-7258 *

Also Published As

Publication number Publication date
WO2007064865A2 (en) 2007-06-07

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