WO2007057768A3 - Derives de sulfonyle - Google Patents

Derives de sulfonyle Download PDF

Info

Publication number
WO2007057768A3
WO2007057768A3 PCT/IB2006/003287 IB2006003287W WO2007057768A3 WO 2007057768 A3 WO2007057768 A3 WO 2007057768A3 IB 2006003287 W IB2006003287 W IB 2006003287W WO 2007057768 A3 WO2007057768 A3 WO 2007057768A3
Authority
WO
WIPO (PCT)
Prior art keywords
sulfonyl derivatives
compounds
sulfonyl
derivatives
hsd
Prior art date
Application number
PCT/IB2006/003287
Other languages
English (en)
Other versions
WO2007057768A2 (fr
Inventor
Hengmiao Cheng
Stephan James Cripps
Jennifer Anne Lafontaine
Phuong Thi Quy Le
Jean Joo Matthews
Sajiv Krishnan Nair
Original Assignee
Pfizer Prod Inc
Hengmiao Cheng
Stephan James Cripps
Jennifer Anne Lafontaine
Phuong Thi Quy Le
Jean Joo Matthews
Sajiv Krishnan Nair
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc, Hengmiao Cheng, Stephan James Cripps, Jennifer Anne Lafontaine, Phuong Thi Quy Le, Jean Joo Matthews, Sajiv Krishnan Nair filed Critical Pfizer Prod Inc
Publication of WO2007057768A2 publication Critical patent/WO2007057768A2/fr
Publication of WO2007057768A3 publication Critical patent/WO2007057768A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96—Sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des composés, des compositions pharmaceutiques contenant ces composés et des procédés destinés à traiter une pathologie liée à la modulation de l’enzyme 11-β-hsd-1.
PCT/IB2006/003287 2005-11-18 2006-11-06 Derives de sulfonyle WO2007057768A2 (fr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US73815405P 2005-11-18 2005-11-18
US60/738,154 2005-11-18
US75375905P 2005-12-23 2005-12-23
US60/753,759 2005-12-23
US79920706P 2006-05-09 2006-05-09
US60/799,207 2006-05-09
US86354206P 2006-10-30 2006-10-30
US60/863,542 2006-10-30

Publications (2)

Publication Number Publication Date
WO2007057768A2 WO2007057768A2 (fr) 2007-05-24
WO2007057768A3 true WO2007057768A3 (fr) 2007-11-01

Family

ID=38049021

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/003287 WO2007057768A2 (fr) 2005-11-18 2006-11-06 Derives de sulfonyle

Country Status (1)

Country Link
WO (1) WO2007057768A2 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007125398A2 (fr) * 2006-04-27 2007-11-08 Pfizer Japan Inc. Sulfonamides
EP2025674A1 (fr) 2007-08-15 2009-02-18 sanofi-aventis Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament
ES2350077B1 (es) 2009-06-04 2011-11-04 Laboratorios Salvat, S.A. Compuestos inhibidores de 11beta-hidroxiesteroide deshidrogenasa de tipo 1.
WO2011107494A1 (fr) 2010-03-03 2011-09-09 Sanofi Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation
US8933024B2 (en) 2010-06-18 2015-01-13 Sanofi Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
US8895552B2 (en) 2010-09-03 2014-11-25 Sumitomo Dainippon Pharma Co., Ltd. Cyclic amide derivative
WO2012120054A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
WO2012120056A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés oxathiazine tétra-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
WO2012120052A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés d'oxathiazine substitués par des carbocycles ou des hétérocycles, leur procédé de préparation, médicaments contenant ces composés et leur utilisation
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2683699B1 (fr) 2011-03-08 2015-06-24 Sanofi Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
KR101332805B1 (ko) * 2011-03-31 2013-11-27 한국화학연구원 아다만틸기를 갖는 설파마이드 유도체 및 이의 약제학적으로 허용 가능한 염
KR101409847B1 (ko) * 2011-08-04 2014-06-27 현대약품 주식회사 인간 11-베타-히드록시스테로이드 탈수소효소 타입 1을 억제하는 화합물 및 이를 포함하는 약학조성물
WO2013020440A1 (fr) * 2011-08-09 2013-02-14 上海医药集团股份有限公司 Dérivés d'amide et son procédé de préparation, composition pharmaceutique et son utilisation
WO2013037390A1 (fr) 2011-09-12 2013-03-21 Sanofi Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
WO2013045413A1 (fr) 2011-09-27 2013-04-04 Sanofi Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b] pyridine-4-carboxylique utilisés comme inhibiteurs de kinase
CN108368041B (zh) * 2015-12-14 2021-09-07 帝斯曼知识产权资产管理有限公司 用于美容用途的(r)-n-(金刚烷基-2-基)吡咯烷-2-甲酰胺衍生物
EP3235813A1 (fr) 2016-04-19 2017-10-25 Cidqo 2012, S.L. Dérivés aza-tétra-cycliques
JP7164521B2 (ja) * 2016-06-21 2022-11-01 オリオン・オフサルモロジー・エルエルシー 炭素環式プロリンアミド誘導体

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004056745A2 (fr) * 2002-12-23 2004-07-08 Janssen Pharmaceutica N.V. Acetamides d'adamantyle utiles comme inhibiteurs de la deshydrogenase 11-beta hydroxysteroide
US20050245745A1 (en) * 2004-04-29 2005-11-03 Link James T Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004056745A2 (fr) * 2002-12-23 2004-07-08 Janssen Pharmaceutica N.V. Acetamides d'adamantyle utiles comme inhibiteurs de la deshydrogenase 11-beta hydroxysteroide
US20050245745A1 (en) * 2004-04-29 2005-11-03 Link James T Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme

Also Published As

Publication number Publication date
WO2007057768A2 (fr) 2007-05-24

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