WO2007035474A3 - Transdermal delivery peptides and method of use thereof - Google Patents

Transdermal delivery peptides and method of use thereof Download PDF

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Publication number
WO2007035474A3
WO2007035474A3 PCT/US2006/036012 US2006036012W WO2007035474A3 WO 2007035474 A3 WO2007035474 A3 WO 2007035474A3 US 2006036012 W US2006036012 W US 2006036012W WO 2007035474 A3 WO2007035474 A3 WO 2007035474A3
Authority
WO
WIPO (PCT)
Prior art keywords
transdermal delivery
peptides
methods
delivery peptides
disclosed
Prior art date
Application number
PCT/US2006/036012
Other languages
French (fr)
Other versions
WO2007035474A2 (en
Inventor
Long-Ping Wen
Yongping Chen
Yuanyuan Shen
Xin Guo
Weiping Wang
Brian M Zhang
Original Assignee
Novomed Technologies Inc Shang
Ustc Univ Science Tech Cn
Long-Ping Wen
Yongping Chen
Yuanyuan Shen
Xin Guo
Weiping Wang
Brian M Zhang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novomed Technologies Inc Shang, Ustc Univ Science Tech Cn, Long-Ping Wen, Yongping Chen, Yuanyuan Shen, Xin Guo, Weiping Wang, Brian M Zhang filed Critical Novomed Technologies Inc Shang
Publication of WO2007035474A2 publication Critical patent/WO2007035474A2/en
Publication of WO2007035474A3 publication Critical patent/WO2007035474A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH] (Somatotropin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Transdermal delivery peptides for the treatment of skin diseases and/or facilitation or enhancement of transdermal delivery of pharmaceutically active agents are provided. Compositions comprising the transdermal delivery peptides and methods of therapeutic use, including the improvement of transdermal delivery of drugs or other pharmaceutically active agents, are also disclosed. Nucleic acids, expression vectors, and methods of their use, which encode the transdermal delivery peptides are disclosed. Methods are also provided for in vivo phage display for identifying further peptides with enhanced transdermal delivery capability.
PCT/US2006/036012 2005-09-15 2006-09-14 Transdermal delivery peptides and method of use thereof WO2007035474A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US71749705P 2005-09-15 2005-09-15
US60/717,497 2005-09-15
US74071305P 2005-11-30 2005-11-30
US60/740,713 2005-11-30

Publications (2)

Publication Number Publication Date
WO2007035474A2 WO2007035474A2 (en) 2007-03-29
WO2007035474A3 true WO2007035474A3 (en) 2008-01-17

Family

ID=37889354

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/036012 WO2007035474A2 (en) 2005-09-15 2006-09-14 Transdermal delivery peptides and method of use thereof

Country Status (1)

Country Link
WO (1) WO2007035474A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8877890B2 (en) 2009-11-23 2014-11-04 Palatin Technologies, Inc. Melanocortin-1 receptor-specific cyclic peptides
US8933194B2 (en) 2009-11-23 2015-01-13 Palatin Technologies, Inc. Melanocortin-1 receptor-specific linear peptides
CN106366161A (en) * 2012-05-31 2017-02-01 Lg生活健康株式会社 Skin-permeating peptide

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008106646A2 (en) * 2007-03-01 2008-09-04 Introgen Therapeutics, Inc Methods and formulations for topical gene therapy
US9815875B2 (en) 2008-02-19 2017-11-14 Myocept Inc. Postsynaptically targeted chemodenervation agents and their methods of use
EP2300036B1 (en) 2008-06-09 2017-04-05 Palatin Technologies, Inc. Melanocortin receptor-specific peptides for treatment of sexual dysfunction
CN102449140B (en) * 2009-03-03 2014-11-26 密执安大学评议会 Methods of inhibiting photoreceptor apoptosis
UY32690A (en) 2009-06-08 2011-01-31 Astrazeneca Ab SPECIFIC PEPTIDES FOR MELANOCORTIN RECEPTORS
KR20130139254A (en) 2010-11-09 2013-12-20 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 Skin permeating and cell entering (space) peptides and methods of use thereof
CN102225206B (en) * 2011-06-17 2013-03-06 中国科学技术大学 Composite for enhancing transdermal administration and application thereof
WO2016033314A1 (en) * 2014-08-27 2016-03-03 The Regents Of The University Of California Skin penetrating peptides (spps) and methods of use therefor
CN108606935A (en) * 2018-05-24 2018-10-02 广州市韵丽生物科技有限公司 A kind of skin care item preparation method containing transdermal small peptide
IL303969A (en) 2021-01-24 2023-08-01 David Forrest Michael Bnjm

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001075067A2 (en) * 2000-03-31 2001-10-11 Hyseq, Inc. Novel nucleic acids and polypeptides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001075067A2 (en) * 2000-03-31 2001-10-11 Hyseq, Inc. Novel nucleic acids and polypeptides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DUERR ET AL.: "Identification of peptide sequences that induce the transport of phage across the gastrointestinal mucosal barrier", JOURNAL OF VIROLOGICAL METHODS, vol. 116, no. 2, 15 March 2004 (2004-03-15), pages 177 - 180, Retrieved from the Internet <URL:http://www.sciencedirect.com/science?ob=Article&_udi=B6T96-4BBMWW9-1&_user=571676&_coverDate=03%2F15%2F2004&_rdoc=10&_fmt=full&_orig=browse&_srch=doc-info(%23toc%235106%232004%23998839997%23476450%23FLA%23display%23Volume)&_cdi=5106&_sort=d&_docanchor=....> *
PRAUSNITZ ET AL.: "Current status and future potential of transdermal drug delivery", NATURE REVIEWS: DRUG DISCOVERY, vol. 3, no. 2, February 2004 (2004-02-01), pages 115 - 124, XP002574503, Retrieved from the Internet <URL:http://www.nature.com.proxy?2.library.uiuc.edu/nrd/journal/v3/n2/abs/nrd1304.html;[sessionid=175FC1AC238377019DD2F08174AEF170]> DOI: doi:10.1038/nrd1304 *
WEINER ET AL.: "Targeted follicular delivery of macromolecules via liposomes", INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 162, no. 1-2, 20 March 1998 (1998-03-20), pages 29 - 38, XP002913863, Retrieved from the Internet <URL:http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T7W3SY3G1W_5&_user=10&_coverDate=03%F20%2F1998&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version1&_urlVersion=0&_userid=10&md5=e6fb9e2d7c41d4ba42c0298b9a602bb1> DOI: doi:10.1016/S0378-5173(97)00409-2 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8877890B2 (en) 2009-11-23 2014-11-04 Palatin Technologies, Inc. Melanocortin-1 receptor-specific cyclic peptides
US8933194B2 (en) 2009-11-23 2015-01-13 Palatin Technologies, Inc. Melanocortin-1 receptor-specific linear peptides
US9447148B2 (en) 2009-11-23 2016-09-20 Palatin Technologies, Inc. Melanocortin-1 receptor-specific cyclic peptides
US9580466B2 (en) 2009-11-23 2017-02-28 Palatin Technologies, Inc. Melanocortin-1 receptor-specific linear peptides
CN106366161A (en) * 2012-05-31 2017-02-01 Lg生活健康株式会社 Skin-permeating peptide
CN106366161B (en) * 2012-05-31 2019-12-06 Lg生活健康株式会社 Skin-permeable peptides

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