WO2007017846A3 - Localization of a radioactive source - Google Patents

Localization of a radioactive source Download PDF

Info

Publication number
WO2007017846A3
WO2007017846A3 PCT/IB2006/052770 IB2006052770W WO2007017846A3 WO 2007017846 A3 WO2007017846 A3 WO 2007017846A3 IB 2006052770 W IB2006052770 W IB 2006052770W WO 2007017846 A3 WO2007017846 A3 WO 2007017846A3
Authority
WO
WIPO (PCT)
Prior art keywords
detector
radiation
relative orientation
working volume
localization
Prior art date
Application number
PCT/IB2006/052770
Other languages
French (fr)
Other versions
WO2007017846A8 (en
WO2007017846A2 (en
Inventor
David Maier Neustadter
Giora Kornblau
Original Assignee
Navotek Medical Ltd
David Maier Neustadter
Giora Kornblau
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IL2005/000871 external-priority patent/WO2006016368A2/en
Application filed by Navotek Medical Ltd, David Maier Neustadter, Giora Kornblau filed Critical Navotek Medical Ltd
Priority to EP06795628A priority Critical patent/EP1922011B1/en
Priority to US11/990,315 priority patent/US7952079B2/en
Priority to AT06795628T priority patent/ATE555737T1/en
Priority to US11/791,890 priority patent/US20090131734A1/en
Publication of WO2007017846A2 publication Critical patent/WO2007017846A2/en
Priority to EP07706152A priority patent/EP1988844B1/en
Priority to PCT/IL2007/000215 priority patent/WO2007094002A2/en
Priority to PCT/IL2007/000214 priority patent/WO2007094001A2/en
Publication of WO2007017846A3 publication Critical patent/WO2007017846A3/en
Publication of WO2007017846A8 publication Critical patent/WO2007017846A8/en
Priority to IL189442A priority patent/IL189442A/en
Priority to IL193412A priority patent/IL193412A0/en
Priority to IL209159A priority patent/IL209159A0/en
Priority to IL209160A priority patent/IL209160A0/en
Priority to IL209161A priority patent/IL209161A0/en
Priority to IL209158A priority patent/IL209158A0/en
Priority to US13/091,775 priority patent/US8198600B2/en
Priority to US13/347,503 priority patent/US20120323117A1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/29—Measurement performed on radiation beams, e.g. position or section of the beam; Measurement of spatial distribution of radiation
    • G01T1/2907—Angle determination; Directional detectors; Telescopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/42—Arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4258—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector for detecting non x-ray radiation, e.g. gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/101—Computer-aided simulation of surgical operations
    • A61B2034/105—Modelling of the patient, e.g. for ligaments or bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A61B2034/2046—Tracking techniques
    • A61B2034/2051—Electromagnetic tracking systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A61B2034/2068—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis using pointers, e.g. pointers having reference marks for determining coordinates of body points
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B2090/101—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis for stereotaxic radiosurgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/392—Radioactive markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/1126—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb using a particular sensing technique
    • A61B5/1127—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb using a particular sensing technique using markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • High Energy & Nuclear Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Robotics (AREA)
  • Nuclear Medicine (AREA)
  • Length-Measuring Devices Using Wave Or Particle Radiation (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

An angle-responsive sensor, comprising: a radiation detector adapted to detect ionizing radiation; at least one radiation absorbing element arranged to block radiation from reaching said detector in a manner dependent on a relative orientation of a radiation source, said detector and said element, said detector and said element defining an aim for said sensor; and circuitry coupled to said detector and which generates an output signal which varies as a function of said relative orientation, wherein said detector and said element are arranged to have a working volume of at least 10 cm in depth and having an angular width, such that said signal defines an accuracy of better than 3 mm within one standard deviation, over said working volume.
PCT/IB2006/052770 2004-08-12 2006-08-10 Localization of a radioactive source WO2007017846A2 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
EP06795628A EP1922011B1 (en) 2005-08-11 2006-08-10 Localization of a radioactive source
US11/990,315 US7952079B2 (en) 2004-08-12 2006-08-10 Localization of a radioactive source
AT06795628T ATE555737T1 (en) 2005-08-11 2006-08-10 LOCALIZATION OF A RADIOACTIVE SOURCE
PCT/IL2007/000214 WO2007094001A2 (en) 2006-02-16 2007-02-15 Implantable medical marker and methods of preparation thereof
PCT/IL2007/000215 WO2007094002A2 (en) 2006-02-16 2007-02-15 Location indication by pointing to an intrabody radiation source
US11/791,890 US20090131734A1 (en) 2006-02-16 2007-02-15 Implantable medical marker and methods of preparation thereof
EP07706152A EP1988844B1 (en) 2006-02-16 2007-02-15 Implantable medical marker and methods of preparation thereof
IL189442A IL189442A (en) 2005-08-11 2008-02-11 Localization of a radioactive source
IL193412A IL193412A0 (en) 2006-02-16 2008-08-12 Implantable medical marker and methods of preparation thereof
IL209159A IL209159A0 (en) 2005-08-11 2010-11-04 Localization of a radioactive source
IL209158A IL209158A0 (en) 2005-08-11 2010-11-04 Localization of a radioactive source
IL209161A IL209161A0 (en) 2005-08-11 2010-11-04 Localization of a radioactive source
IL209160A IL209160A0 (en) 2005-08-11 2010-11-04 Localization of a radioactive source
US13/091,775 US8198600B2 (en) 2004-08-12 2011-04-21 Localization of a radioactive source
US13/347,503 US20120323117A1 (en) 2006-02-16 2012-01-10 Implantable Medical Marker and Methods of Preparation Thereof

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
PCT/IL2005/000871 WO2006016368A2 (en) 2004-08-12 2005-08-11 Localization of a radioactive source within a body of a subject
ILPCT/IL2005/000871 2005-08-11
US77393006P 2006-02-16 2006-02-16
US77393106P 2006-02-16 2006-02-16
US60/773,931 2006-02-16
US60/773,930 2006-02-16
US80417806P 2006-06-08 2006-06-08
US60/804,178 2006-06-08

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2005/000871 Continuation-In-Part WO2006016368A2 (en) 2004-08-12 2005-08-11 Localization of a radioactive source within a body of a subject

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US11/990,315 A-371-Of-International US7952079B2 (en) 2004-08-12 2006-08-10 Localization of a radioactive source
PCT/IB2006/052771 Continuation-In-Part WO2007017847A1 (en) 2004-08-12 2006-08-10 Medical treatment system and method using radioactivity based position sensor
US13/091,775 Division US8198600B2 (en) 2004-08-12 2011-04-21 Localization of a radioactive source

Publications (3)

Publication Number Publication Date
WO2007017846A2 WO2007017846A2 (en) 2007-02-15
WO2007017846A3 true WO2007017846A3 (en) 2007-09-07
WO2007017846A8 WO2007017846A8 (en) 2007-11-29

Family

ID=37500052

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/052770 WO2007017846A2 (en) 2004-08-12 2006-08-10 Localization of a radioactive source

Country Status (3)

Country Link
US (2) US7952079B2 (en)
EP (1) EP1922011B1 (en)
WO (1) WO2007017846A2 (en)

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