WO2007016350A3 - Preparation en comprimes a liberation modifiee presentant des proprietes mecaniques ameliorees - Google Patents
Preparation en comprimes a liberation modifiee presentant des proprietes mecaniques ameliorees Download PDFInfo
- Publication number
- WO2007016350A3 WO2007016350A3 PCT/US2006/029427 US2006029427W WO2007016350A3 WO 2007016350 A3 WO2007016350 A3 WO 2007016350A3 US 2006029427 W US2006029427 W US 2006029427W WO 2007016350 A3 WO2007016350 A3 WO 2007016350A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- mechanical properties
- modified release
- release tablet
- tablet formulations
- enhanced mechanical
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne un procédé de préparation d'un médicament sous forme posologique solide présentant une dureté spécifiée, ce médicament contenant au moins un agent pharmaceutiquement actif présentant un profil de libération dépendant du pH, au moins un agent à libération prolongée non dépendante du pH, et une dose efficace d'Eudragit L100-55.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002616845A CA2616845A1 (fr) | 2005-07-28 | 2006-07-28 | Preparation en comprimes a liberation modifiee presentant des proprietes mecaniques ameliorees |
EP06788799A EP1909767A2 (fr) | 2005-07-28 | 2006-07-28 | Preparation en comprimes a liberation modifiee presentant des proprietes mecaniques ameliorees |
JP2008524198A JP2009502957A (ja) | 2005-07-28 | 2006-07-28 | 機械的特性の向上した徐放性錠剤配合物 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70300005P | 2005-07-28 | 2005-07-28 | |
US60/703,000 | 2005-07-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007016350A2 WO2007016350A2 (fr) | 2007-02-08 |
WO2007016350A3 true WO2007016350A3 (fr) | 2007-05-31 |
Family
ID=37692541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/029427 WO2007016350A2 (fr) | 2005-07-28 | 2006-07-28 | Preparation en comprimes a liberation modifiee presentant des proprietes mecaniques ameliorees |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1909767A2 (fr) |
JP (1) | JP2009502957A (fr) |
CA (1) | CA2616845A1 (fr) |
WO (1) | WO2007016350A2 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009087663A2 (fr) * | 2007-11-30 | 2009-07-16 | Sun Pharmaceutical Industries Ltd. | Comprimé oral enrobé à libération contrôlée |
LT2364360T (lt) | 2008-11-13 | 2017-08-10 | Nogra Pharma Limited | Priešprasmės kompozicijos ir jų gavimo bei panaudojimo būdai |
AT10562U3 (de) * | 2008-12-05 | 2010-01-15 | Aop Orphan Pharmaceuticals Ag | Neuartige zusammensetzung zur behandlung einer essenziellen thrombozytämie |
PL2531181T3 (pl) * | 2010-02-03 | 2019-09-30 | Pharma Two B Ltd. | Preparaty rasagiliny o przedłużonym uwalnianiu i ich zastosowanie |
CN102138906B (zh) * | 2011-04-11 | 2012-09-05 | 合肥合源药业有限公司 | 一种盐酸可乐定缓释微丸制剂 |
TW202400130A (zh) | 2022-06-15 | 2024-01-01 | 日商澤井製藥股份有限公司 | 含胍法辛鹽酸鹽製劑 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020168404A1 (en) * | 1998-07-20 | 2002-11-14 | Isabelle Rault | Use of an acrylic type polymer as disintegrating agent |
US6811794B2 (en) * | 2001-12-20 | 2004-11-02 | Shire Laboratories, Inc. | Sustained release pharmaceutical dosage forms with minimized pH dependent dissolution profiles |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6303607B1 (en) * | 1998-09-10 | 2001-10-16 | Cv Therapeutics, Inc. | Method for administering a sustained release ranolanolazine formulation |
-
2006
- 2006-07-28 WO PCT/US2006/029427 patent/WO2007016350A2/fr active Application Filing
- 2006-07-28 JP JP2008524198A patent/JP2009502957A/ja active Pending
- 2006-07-28 EP EP06788799A patent/EP1909767A2/fr not_active Withdrawn
- 2006-07-28 CA CA002616845A patent/CA2616845A1/fr not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020168404A1 (en) * | 1998-07-20 | 2002-11-14 | Isabelle Rault | Use of an acrylic type polymer as disintegrating agent |
US6811794B2 (en) * | 2001-12-20 | 2004-11-02 | Shire Laboratories, Inc. | Sustained release pharmaceutical dosage forms with minimized pH dependent dissolution profiles |
Non-Patent Citations (3)
Title |
---|
OFOEFULE S I ET AL: "USE OF ACRYCLIC AND METACRYLIC ACID DERIVATIVES AS SUSTAINED RELEASE MATRICES FOR THEOPHYLLINE HYDRATE TABLETS", BOLLETTINO CHIMICO FARMACEUTICO, SOCIETA EDITORIALE FARMACEUTICA, MILANO, IT, vol. 138, no. 10, 1999, pages 526 - 530, XP001030890, ISSN: 0006-6648 * |
SCHULZE M D ET AL: "Indices of tableting performance for acrylic resin polymers with plastic and brittle drugs", DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY 1993 UNITED STATES, vol. 19, no. 12, 1993, pages 1393 - 1411, XP008077210, ISSN: 0363-9045 * |
TAKKA S ET AL: "INFLUENCE OF METHACRYLIC ACID AND HYDROXYPROPYLMETHYL CELLULOSE ON THE TABLET PROPERTIES AND IN VITRO RELEASE OF DEXTROMETHORPHAN HYDROBROMIDE", PHARMAZIE, DIE, GOVI VERLAG, ESCHBORN, DE, vol. 58, no. 12, December 2003 (2003-12-01), pages 886 - 890, XP001178399, ISSN: 0031-7144 * |
Also Published As
Publication number | Publication date |
---|---|
JP2009502957A (ja) | 2009-01-29 |
EP1909767A2 (fr) | 2008-04-16 |
WO2007016350A2 (fr) | 2007-02-08 |
CA2616845A1 (fr) | 2007-02-08 |
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