WO2007014545A2 - Appareil d'electrocardiographie mobile - Google Patents

Appareil d'electrocardiographie mobile Download PDF

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Publication number
WO2007014545A2
WO2007014545A2 PCT/DE2006/001282 DE2006001282W WO2007014545A2 WO 2007014545 A2 WO2007014545 A2 WO 2007014545A2 DE 2006001282 W DE2006001282 W DE 2006001282W WO 2007014545 A2 WO2007014545 A2 WO 2007014545A2
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WO
WIPO (PCT)
Prior art keywords
ecg
memory
mobile
electrodes
unit
Prior art date
Application number
PCT/DE2006/001282
Other languages
German (de)
English (en)
Other versions
WO2007014545A3 (fr
Inventor
Markus Riemenschneider
Klaus Bonaventura
Thomas Doerr
Original Assignee
Markus Riemenschneider
Klaus Bonaventura
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Markus Riemenschneider, Klaus Bonaventura filed Critical Markus Riemenschneider
Priority to DE112006002661T priority Critical patent/DE112006002661A5/de
Publication of WO2007014545A2 publication Critical patent/WO2007014545A2/fr
Publication of WO2007014545A3 publication Critical patent/WO2007014545A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/332—Portable devices specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0462—Apparatus with built-in sensors
    • A61B2560/0468—Built-in electrodes

Definitions

  • the present invention relates to a mobile ECG device.
  • Coronary heart disease is one of the leading causes of death. For example, several hundred thousand people in Germany suffer from a heart attack each year. The medical follow-up after such a heart attack makes a regular check of the heart activity over a longer period necessary. Likewise, heart disease or precautionary measures may require repeated monitoring of cardiac activity over an extended period of time.
  • a sequence of electrical discharges is generated periodically, forming a regular but complex waveform. From this waveform, it can be seen whether the cardiac activity is normal or if there is a deviation from normal cardiac activity.
  • Monitoring cardiac activity therefore typically involves monitoring and recording the waveform.
  • electrodes are placed on the body, which measure skin potentials, which are subject to fluctuations in function of the heart activity.
  • the recorded waveform is commonly referred to as an electrocardiogram or ECG for short.
  • ECG electrocardiogram
  • Cardiac monitoring systems have been developed. Such a system is described for example in US 6,073,046. The portable described there
  • ECG device is equipped with a number of electrodes which are attached to the body of the patient and the electrical influenced by the heart
  • Measure potentials The recorded potentials are collected and forwarded to a central facility, where, for example, a doctor can assess the patient's ECG.
  • a mobile telephone is known, on the back of which four electrodes are arranged, which can be placed on the chest of a human and with whose help electrical potentials of the heart are detected, from which an ECG is derived.
  • the derived ECG is then forwarded to an emergency center, where decisions are made based on the received ECG.
  • EP 0 965 115 B1 is to be used as an emergency call device, the patient must decide for himself whether he should use the device in order to trigger an emergency call. However, it is not always easy for the patient to recognize whether an acute danger situation exists for him. On the other hand, if he recognizes the danger situation, it may already be too late for successful treatment.
  • An early detection or early warning for example, includes the request to see a doctor, is therefore possible only with a more or less permanent monitoring, which, as described above, is associated with great effort.
  • the object of the present invention is therefore to provide a mobile ECG device which makes it possible to check the cardiac activity triggered by a patient and is able to recognize a dangerous situation and be used flexibly.
  • An inventive mobile ECG device comprises:
  • a number of electrodes adapted for application to the body of a patient and for receiving electrical signals of the heart
  • a processor unit configured to derive an ECG from the received electrical signals
  • comparison unit connected to the memory for receiving the reference ECG and to the processor unit for receiving the ECG derived from the electrical signals, configured to compare the derived ECG to the reference ECG.
  • the comparison unit can be realized as a hardware module or as a software module.
  • an individual ECG of the patient is stored in the memory as a reference ECG.
  • the mobile ECG device makes it possible to detect changes in cardiac activity early on the basis of the comparison of the currently derived ECG with the stored individual reference ECG and thus provide a basis for the early issuance of a cardiac output Warning, for example, in the form "Please look for a doctor to spend.
  • the reference ECG is an individual ECG of the patient
  • the mobile ECG device allows the patient's medical history to be taken into account when compared to the derived ECG.
  • heart disease can lead to changes in the ECG that would be normal for the sick patient, whereas for a person with normal heart activity, they would give reason to visit a doctor.
  • the mobile ECG device would hardly be usable in people with pre-existing conditions of the heart because it would constantly produce warning messages that the patient does not need. With an individual ECG of the patient as a reference ECG, such unnecessary alerts can be avoided, so that the device is more flexible than if it contained a standardized reference ECG.
  • the mobile ECG device thus offers, in particular, the possibility of monitoring the heart activity of a patient without transmitting the ECG to a central station, where it is examined by medically trained personnel taking into account the patient's previous history.
  • a significant reduction in the cost of monitoring the cardiac activity of a patient can be achieved.
  • the mobile ECG device comprises a classification unit connected to the comparison unit for receiving the comparison result, which is configured to classify the comparison result into one of at least two classes to which an item of information may be assigned.
  • the classification unit can also be designed as a software module or as a hardware module. Possible information here in particular the information "reaction required” or "no reaction required” in question.
  • the mobile ECG device further comprises one with the classification unit for receiving the classification result connected signal generator, which is designed to output the associated information in the case of a predetermined classification result.
  • One of the possible signals may in particular be a request to visit a doctor and may be output, for example, visually or acoustically. If the classification unit has more than two classes into which the comparison result can be classified, a gradual warning of the patient is also possible, for example "find a doctor at the next opportunity", “seek out a heart specialist immediately”, etc.
  • the mobile ECG device has a writing unit connected to both the processor unit and the memory, and there is also a triggering element connected to the writing unit and externally operable, which is designed to write when actuated trigger the current ECG as a reference ECG in the memory by the writing unit, the stored in the memory reference ECG can be updated at any time. In this way, it is possible to respond appropriately to changes in the clinical picture of the patient. It is not necessary to specify a reference ECG stored once.
  • the writing unit can be designed as a hardware module or as a software module.
  • the ECG device may be equipped with an output device, such as an LCD monitor, on the front side. A brief summary of the findings or a warning message can be displayed on this monitor.
  • the ECG device may have a back with four electrodes, which is designed to be placed on the chest of the patient. The patient can then simply place the device on the chest with the back of the device and press a shutter button to record an ECG.
  • the simple and uncomplicated handling that is possible with it increases the comfort of the patient when creating an ECG and reduces the number of possible sources of error.
  • the mobile ECG device can have a connection for connecting an electrode cable, with at least 4 electrodes.
  • the use of the electrode cable increases the possibilities of using the ECG device and, in particular, allows operation in a coronary mode in which it is possible to detect circulatory disturbances of the heart.
  • the processor unit is equipped with an algorithm which is designed to derive a so-called 12-channel ECG from the signals of the four electrodes. Using the 12-lead ECG, a more detailed analysis of the heart condition is possible than with simple so-called 1-channel ECG or a 3-lead ECG.
  • the ECG device also includes a communication interface, which is designed for wireless or wired communication with other devices.
  • the wireless communication can take place, for example, on protocols such as Bluetooth, WLAN, etc.
  • a wired interfaces for example, parallel interfaces or USB interfaces in question.
  • the communication interface allows communication with computers or personal digital assistants (PDAs), as well as communication with a modem to transmit a derived ECG to a location with trained medical personnel. The latter may in particular be desired if the comparison with the reference ECG reveals that a doctor should be visited and the doctor should be informed in advance that the triggering ECG is to be sighted.
  • the reference memory comprises a database in which personal ECG data of the patient are stored.
  • the ECGs of the past days can be stored, so that a doctor can get an overview of the course of the medical history of the last days by sifting the ECGs stored in the database.
  • the mobile ECG device may also include at least two memory or database areas assigned to different patients can be. It then has a switching device which enables a switching of the access by the comparison unit from the one memory or database area to the other memory or database area.
  • a separate reference ECG can be stored for a number of patients.
  • the mobile ECG device can then be used by several patients at the same time to monitor the heart activity.
  • the memory or database areas can here be embodied as objectively separate memories or databases or as logically separate memories or databases, for example in the form of different sections of the same memory or the same database.
  • Fig. 1 shows an inventive ECG device in a perspective view.
  • FIG. 2 shows the rear side of the mobile ECG device shown in FIG. 1.
  • Fig. 3 shows the internal structure of the ECG device according to the invention as a block diagram.
  • Fig. 4 shows the structure of the microcontroller of Fig. 3 in the form of a block diagram.
  • FIG. 1 An embodiment of the mobile ECG device according to the invention is shown in Fig. 1 in a perspective view. The back of the mobile ECG device 1 is shown in FIG.
  • the electrodes 3 to 9 essentially form the corners of a square ö
  • the front of the mobile ECG device is equipped with an input device in the form of, for example, a keypad 11 and an output device in the form of, for example, an LCD monitor 13.
  • the keypad 11 is for operating the device, the monitor 13 for outputting an examination result after performing an ECG recording and issuing a warning message, if necessary.
  • the mobile ECG device 1 is equipped with a connection 15 to which a cable with external electrodes can be connected, for example, by means of a connector.
  • a connection 15 to which a cable with external electrodes can be connected, for example, by means of a connector.
  • the cable only needs to have 4 electrodes and allows greater freedom in placing the electrodes on the body. More details are given below.
  • the mobile ECG device 1 further comprises a communication interface 17, which enable communication of the device with other devices, such as a PC, a PDA, etc.
  • the wireless communication interface 17 is designed as an infrared interface, but it may alternatively be designed, for example, as a Bluetooth interface, WLAN interface, DECT interface, GSM interface, etc ..
  • the design as an interface for a wired communication for example as a USB interface, serial interface, parallel interface, etc, is possible. If a routine examination is to be performed or if chest discomfort occurs, the device with the four attachment electrodes 3 to 9 can be placed on the chest and a start button on the keypad 11 can be actuated. Pressing the start button will trigger the recording of an ECG and its interpretation.
  • the interpretation result is finally output on the monitor 13.
  • a warning message may also be issued.
  • the device 1 can be equipped with several operating modes. For example, there may be a mode in which only cardiac arrhythmias are judged. In this case, the apparatus can be used alone with the four rear electrodes 9 to 13. It is preferably still another mode, the so-called coronary mode, available, in which also circulatory disorders can be assessed. In this mode, the electrode cable is used with the at least four external electrodes. To record an ECG in coronary mode, apply the electrodes to the back of the neck and chest and then press the shutter button on the keypad 11.
  • the heart rate is displayed on the monitor 13. After the internal
  • This recommendation may, for example, "No special finding, therefore no action needed", "Please visit a doctor at the next opportunity”, “Please see a cardiologist as soon as possible”, etc.
  • FIG. 3 The internal structure of the mobile ECG device 1 according to the invention is shown in FIG. 3 in the form of a block diagram. This shows in a highly schematic representation of the electrodes 3, 5, 7, 9 on the back of the device 1 and a connected electrode cable with four external electrodes 102, 105, 107 and 109.
  • the device further comprises an ECG amplifier 19, an A. / D converter 21, a microcontroller 23 and a nonvolatile memory 25, for example in the form of an EPROM, an EEPROM, a flash EPROM, etc., and a RAM memory 27, that is, a memory with random access.
  • the ECG amplifier 19 is connected to the electrodes 3, 5, 7, 9 or 103, 105, 107, 109 for receiving the signals measured by them. It amplifies the signals of the electrodes and outputs them to the A / D converter 21 Next, which converts the previously analog signals into digital signals. The digital signals are finally read out by the microcontroller 23, which performs the evaluation and interpretation of the potentials picked up by the electrodes. For this he accesses stored in the non-volatile memory 25 reference data, which represent a reference ECG. As a reference data or reference ECG, an EKG recorded by the patient at an earlier time is stored here in the non-volatile memory.
  • the non-volatile memory may include a database with a number of prior findings of the patient.
  • the database or the non-volatile memory may be divided into several memory areas that are assigned to different patients.
  • the non-volatile memory may contain reference ECGs for multiple patients and, if appropriate, previous findings from these patients. This can include other important data such as blood type or other diseases or the like.
  • the RAM memory 27 serves only as a working memory for the microcontroller 23.
  • the internal structure of the microcontroller is shown in FIG. 4 in the form of a block switch.
  • the microcontroller 23 comprises a processor unit 231 which reads out the output signals of the A / D converter, a comparison unit 233 connected to the processor unit 231 and a classification unit 235 connected to the comparison unit.
  • the described structure can be realized as a hardware structure of the microcontroller. Preferably, however, it is realized in the form of software modules.
  • the microcontroller 23 also comprises a writing unit 237 and as a triggering element, for example, via the keypad 11 to be actuated trigger circuit 239.
  • the writing unit 237 and the trigger circuit 239 are designed to actuate the .
  • Trigger circuit 239 to write a new reference ECG in the non-volatile memory 25.
  • the trigger circuit 239 is executed in the present embodiment in the form of a push button eg. On the keypad 11. If the input device 11 and the output device 13 are implemented in the form of a touchscreen, the triggering element can also be realized via the touchscreen by means of a suitable software module.
  • the writing unit 237 may, for example, be designed as a hardware component of the microcontroller 23. Preferably, however, it is implemented as software.
  • this is at least partially designed as a programmable read-only memory, in particular as electrically erasable and programmable read-only memory EEPROM (electrical erasable p_rogrammable read only memory). Alternatively, however, other forms of programmable read-only memory may be used.
  • EEPROM electrically erasable and programmable read-only memory
  • other forms of programmable read-only memory may be used.
  • the use of a programmable read-only memory as a non-volatile memory 25 also allows updating the software of the ECG device and the database with the patient data.
  • the ECG device may also include a filter (not shown) that removes or suppresses interferences such as noise or artifacts due to muscle tensions in the analog or digital signals.
  • the filter can also be implemented as a hardware component or realized in the form of a suitable filter software.
  • the processor unit 231 reads out the digital ECG data from the A / D converter 21. It serves as the central control unit of the microcontroller 23.
  • the comparison unit 233 receives from the processor unit 231 the derived ECG. It also receives the individual reference ECG from the nonvolatile memory 25 and compares it to the derived ECG.
  • the comparison result is forwarded to the classification unit 235 which, according to various, in particular, medical criteria, places it in one of at least two classes divides.
  • the classes are associated with various information to be displayed on the display element 13 or notifications.
  • the classification in the classification unit 235 takes place in particular on the basis of medically relevant criteria, which may be given for example by certain parameters of an ECG or by a specific course of the ECG.
  • One of the classes into which the comparison result can be classified is that the comparison between the derived ECG and the reference ECG does not provide any medically relevant findings. Otherwise, the comparison result is classified into the other class, which stands for a medically relevant finding, which causes the microcontroller 23 to issue a warning message, for example, "Please see a doctor at the next opportunity," on the display element 13.
  • a medically relevant finding which causes the microcontroller 23 to issue a warning message, for example, "Please see a doctor at the next opportunity," on the display element 13.
  • an output is made on the display unit 13, for example, "No particular finding".
  • the processor unit 231 in the microcontroller 23 is equipped in particular with an algorithm which determines a so-called 12-channel ECG from the signals recorded by the four electrodes 103, 105, 107, 109 of the electrode cable by scaling and combining them.
  • an algorithm which determines a so-called 12-channel ECG from the signals recorded by the four electrodes 103, 105, 107, 109 of the electrode cable by scaling and combining them.
  • they are attached to the back of the neck of the patient and to his chest such that the electrode positions represent the tips of a tetrahedron. in the center of which is the heart.
  • the processor 231 is also formed in the present embodiment for deriving a so-called vector ECG from the signals of the four electrodes 103, 105, 107, 109 of the electrode cable.
  • a vector ECG the potential differences are treated as if they were generated by an electric dipole, which is in place of the heart.
  • An electric dipole represents a directional quantity that can be described in the form of a vector.
  • both the magnitude and orientation of the cardiac vector vary.
  • the components of the heart vector are now determined over a heart cycle, for example in a Cartesian coordinate system in which all coordinate axes are perpendicular to one another.
  • the information about the heart activity is then in the fluctuations of the vector components over a cardiac cycle.
  • the comparison of the recorded ECG with the reference ECG and the interpretation of the comparison result in the ECG device according to the invention can be carried out on the basis of the vector ECG data. Determining the 12-lead ECG is not absolutely necessary. However, the 12-lead ECG makes it easier for a physician to interpret the ECG data because it is similar to conventional cardiac or hospital-derived ECGs.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

L'invention concerne un appareil d'électrocardiographie mobile (1) comportant une pluralité d'électrodes (3, 5, 7, 9, 103, 105, 107, 109) conçues pour être fixées sur le corps d'un patient et pour recevoir des signaux électriques du coeur, une unité de traitement (231) conçue pour réaliser un électrocardiogramme à partir des signaux électriques reçus, une mémoire (25) à l'intérieur de laquelle un électrocardiogramme de référence est mémorisé ainsi qu'une unité de comparaison (233) reliée à la mémoire (25) pour recevoir l'électrocardiogramme de référence et à l'unité de traitement (231) pour recevoir l'électrocardiogramme réalisé à partir des signaux électriques, laquelle unité de comparaison est conçue pour comparer l'électrocardiogramme réalisé avec l'électrocardiogramme de référence. L'électrocardiogramme de référence mémorisé est un électrocardiogramme individuel du patient.
PCT/DE2006/001282 2005-07-30 2006-07-26 Appareil d'electrocardiographie mobile WO2007014545A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE112006002661T DE112006002661A5 (de) 2005-07-30 2006-07-26 Mobiles EKG-Gerät

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005036501A DE102005036501A1 (de) 2005-07-30 2005-07-30 EKG-Gerät
DE102005036501.9 2005-07-30

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WO2007014545A2 true WO2007014545A2 (fr) 2007-02-08
WO2007014545A3 WO2007014545A3 (fr) 2007-06-21

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Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010018566A1 (fr) * 2008-08-14 2010-02-18 David Amitai Dispositif d'acquisition de données d'électrocardiogramme
US8301232B2 (en) 2010-06-08 2012-10-30 Alivecor, Inc. Wireless, ultrasonic personal health monitoring system
US8509882B2 (en) 2010-06-08 2013-08-13 Alivecor, Inc. Heart monitoring system usable with a smartphone or computer
CN103330561A (zh) * 2013-06-07 2013-10-02 北京丰拓生物技术有限公司 心电测量装置
US8700137B2 (en) 2012-08-30 2014-04-15 Alivecor, Inc. Cardiac performance monitoring system for use with mobile communications devices
US9220430B2 (en) 2013-01-07 2015-12-29 Alivecor, Inc. Methods and systems for electrode placement
US9247911B2 (en) 2013-07-10 2016-02-02 Alivecor, Inc. Devices and methods for real-time denoising of electrocardiograms
US9254092B2 (en) 2013-03-15 2016-02-09 Alivecor, Inc. Systems and methods for processing and analyzing medical data
US9254095B2 (en) 2012-11-08 2016-02-09 Alivecor Electrocardiogram signal detection
US9351654B2 (en) 2010-06-08 2016-05-31 Alivecor, Inc. Two electrode apparatus and methods for twelve lead ECG
US9420956B2 (en) 2013-12-12 2016-08-23 Alivecor, Inc. Methods and systems for arrhythmia tracking and scoring
US9839363B2 (en) 2015-05-13 2017-12-12 Alivecor, Inc. Discordance monitoring
US11375938B2 (en) 2008-08-14 2022-07-05 Ticker Medical Ltd Miniature ECG data acquisition device

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CN105496401A (zh) * 2016-02-23 2016-04-20 宫志华 一种心电图手持设备
NL2021115B1 (en) * 2018-06-13 2019-12-19 Stichting Cardiovasculaire Biologie Scb Device for recording a multi-channel-ecg using and a method there for

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Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8082025B2 (en) * 2008-08-14 2011-12-20 David Amitai ECG data acquisition device
US11375938B2 (en) 2008-08-14 2022-07-05 Ticker Medical Ltd Miniature ECG data acquisition device
US11707218B2 (en) 2008-08-14 2023-07-25 Ticker Medical Ltd Miniature ECG data acquisition device
WO2010018566A1 (fr) * 2008-08-14 2010-02-18 David Amitai Dispositif d'acquisition de données d'électrocardiogramme
US9351654B2 (en) 2010-06-08 2016-05-31 Alivecor, Inc. Two electrode apparatus and methods for twelve lead ECG
US8301232B2 (en) 2010-06-08 2012-10-30 Alivecor, Inc. Wireless, ultrasonic personal health monitoring system
US8509882B2 (en) 2010-06-08 2013-08-13 Alivecor, Inc. Heart monitoring system usable with a smartphone or computer
US11382554B2 (en) 2010-06-08 2022-07-12 Alivecor, Inc. Heart monitoring system usable with a smartphone or computer
US9026202B2 (en) 2010-06-08 2015-05-05 Alivecor, Inc. Cardiac performance monitoring system for use with mobile communications devices
US9833158B2 (en) 2010-06-08 2017-12-05 Alivecor, Inc. Two electrode apparatus and methods for twelve lead ECG
US9649042B2 (en) 2010-06-08 2017-05-16 Alivecor, Inc. Heart monitoring system usable with a smartphone or computer
US8700137B2 (en) 2012-08-30 2014-04-15 Alivecor, Inc. Cardiac performance monitoring system for use with mobile communications devices
US9254095B2 (en) 2012-11-08 2016-02-09 Alivecor Electrocardiogram signal detection
US10478084B2 (en) 2012-11-08 2019-11-19 Alivecor, Inc. Electrocardiogram signal detection
US9579062B2 (en) 2013-01-07 2017-02-28 Alivecor, Inc. Methods and systems for electrode placement
US9220430B2 (en) 2013-01-07 2015-12-29 Alivecor, Inc. Methods and systems for electrode placement
US9254092B2 (en) 2013-03-15 2016-02-09 Alivecor, Inc. Systems and methods for processing and analyzing medical data
CN103330561A (zh) * 2013-06-07 2013-10-02 北京丰拓生物技术有限公司 心电测量装置
US9247911B2 (en) 2013-07-10 2016-02-02 Alivecor, Inc. Devices and methods for real-time denoising of electrocardiograms
US9681814B2 (en) 2013-07-10 2017-06-20 Alivecor, Inc. Devices and methods for real-time denoising of electrocardiograms
US9420956B2 (en) 2013-12-12 2016-08-23 Alivecor, Inc. Methods and systems for arrhythmia tracking and scoring
US10159415B2 (en) 2013-12-12 2018-12-25 Alivecor, Inc. Methods and systems for arrhythmia tracking and scoring
US9572499B2 (en) 2013-12-12 2017-02-21 Alivecor, Inc. Methods and systems for arrhythmia tracking and scoring
US10537250B2 (en) 2015-05-13 2020-01-21 Alivecor, Inc. Discordance monitoring
US9839363B2 (en) 2015-05-13 2017-12-12 Alivecor, Inc. Discordance monitoring

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DE112006002661A5 (de) 2008-07-10
DE102005036501A1 (de) 2007-02-01
WO2007014545A3 (fr) 2007-06-21

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