WO2007011740A2 - A powder mix of potassium calcium citrate for the treatment of kidney stones and osteoporosis - Google Patents

A powder mix of potassium calcium citrate for the treatment of kidney stones and osteoporosis Download PDF

Info

Publication number
WO2007011740A2
WO2007011740A2 PCT/US2006/027398 US2006027398W WO2007011740A2 WO 2007011740 A2 WO2007011740 A2 WO 2007011740A2 US 2006027398 W US2006027398 W US 2006027398W WO 2007011740 A2 WO2007011740 A2 WO 2007011740A2
Authority
WO
WIPO (PCT)
Prior art keywords
calcium
citrate
potassium
meq
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/027398
Other languages
English (en)
French (fr)
Other versions
WO2007011740A3 (en
Inventor
Charles Y. C. Pak
Khashayar Sakhaee
Neill B. Walsdorf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Mission Pharmacal Co
University of Texas at Austin
Original Assignee
University of Texas System
Mission Pharmacal Co
University of Texas at Austin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Texas System, Mission Pharmacal Co, University of Texas at Austin filed Critical University of Texas System
Priority to AU2006270162A priority Critical patent/AU2006270162B2/en
Priority to JP2008521643A priority patent/JP2009514786A/ja
Priority to EP06787322A priority patent/EP1922064A4/en
Publication of WO2007011740A2 publication Critical patent/WO2007011740A2/en
Anticipated expiration legal-status Critical
Publication of WO2007011740A3 publication Critical patent/WO2007011740A3/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Definitions

  • composition is administered orally as an aqueous solution; however, other forms of administration and other forms of the composition known to those skilled in the art (e.g., suspensions, or solid dosage forms such as tablets, etc.) are also part of the present invention.
  • Citric acid-H 2 O g 1.402 1.752 2.103 2.804 3.380 4.206

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
PCT/US2006/027398 2005-07-15 2006-07-13 A powder mix of potassium calcium citrate for the treatment of kidney stones and osteoporosis Ceased WO2007011740A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2006270162A AU2006270162B2 (en) 2005-07-15 2006-07-13 A powder mix of potassium calcium citrate for the treatment of kidney stones and osteoporosis
JP2008521643A JP2009514786A (ja) 2005-07-15 2006-07-13 腎結石及び骨粗鬆症の処置のためのクエン酸カリウムカルシウムの粉末混合物
EP06787322A EP1922064A4 (en) 2005-07-15 2006-07-13 PULSE MIXTURE OF CALIUM CALCIUM CITRATE FOR THE TREATMENT OF KIDNEY STONES AND OSTEOPOROSIS

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/183,140 US20070077314A1 (en) 2005-07-15 2005-07-15 Powder mix of potassium calcium citrate for the treatment of kidney stones and osteoporosis
US11/183,140 2005-07-15

Publications (2)

Publication Number Publication Date
WO2007011740A2 true WO2007011740A2 (en) 2007-01-25
WO2007011740A3 WO2007011740A3 (en) 2009-04-30

Family

ID=37669400

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/027398 Ceased WO2007011740A2 (en) 2005-07-15 2006-07-13 A powder mix of potassium calcium citrate for the treatment of kidney stones and osteoporosis

Country Status (5)

Country Link
US (2) US20070077314A1 (enExample)
EP (1) EP1922064A4 (enExample)
JP (1) JP2009514786A (enExample)
AU (1) AU2006270162B2 (enExample)
WO (1) WO2007011740A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015120272A1 (en) * 2014-02-06 2015-08-13 University Of Houston System Organic acids as growth inhibitors of pathological calcification and uses thereof
WO2016159897A1 (en) * 2015-04-01 2016-10-06 Ay Doğan Potassium citrate suspension
US10285961B2 (en) 2014-02-06 2019-05-14 University Of Houston System Organic acids as agents to dissolve calcium minerals in pathological calcification and uses thereof
IT202200021258A1 (it) * 2022-10-14 2024-04-14 Neilos S R L “Composizione nutraceutica o farmaceutica per il benessere renale”

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9278112B2 (en) * 2013-03-15 2016-03-08 New York University Citrate containing beverage
US9529465B2 (en) * 2013-12-02 2016-12-27 At&T Intellectual Property I, L.P. Secure interaction with input devices
CN104069125B (zh) * 2014-07-16 2017-02-08 华南理工大学 一种用于泌尿系磷酸盐结石的溶石剂及其制备方法
WO2019035989A1 (en) * 2017-08-17 2019-02-21 The Board Of Regents Of The University Of Texas System PREVENTION OF CALCIUM OXALATE RENAL CALCULATIONS BY POTASSIUM HYDROXYCITRATE

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4722847A (en) 1986-05-07 1988-02-02 The Procter & Gamble Company Fruit juice beverages and juice concentrates nutritionally supplemented with calcium
US4871554A (en) 1987-08-12 1989-10-03 Coca-Cola Company Calcium fortified food product
US6319490B1 (en) 1996-02-20 2001-11-20 Smithkline Beecham Plc Liquid oral compositions comprising a calcium compound and an acidulant
US6680305B1 (en) 1993-06-04 2004-01-20 Biotime, Inc. Physiologically acceptable aqueous solutions and methods for their use
US20040185119A1 (en) 2003-02-26 2004-09-23 Theuer Richard C. Method and compositions for treating gastric hyperacidity while diminishing the likelihood of producing vitamin deficiency

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888182A (en) * 1983-04-11 1989-12-19 Board Of Regents Of The University Of Texas System Compositions and methods of treating calcium renal stones
US4772467A (en) * 1985-02-19 1988-09-20 Board Of Regents, U T Systems Osteoporosis inhibition by dietary calcium supplementation
US5128374A (en) * 1987-08-28 1992-07-07 The Procter & Gamble Company Use of calcium citrate malate for the treatment of osteoporosis and related disorders
ES2061394B1 (es) * 1993-02-05 1995-06-16 Robert S A Lab Procedimiento de fabricacion de un granulado de citrato potasico con cesion retardada.
DE19503190A1 (de) * 1995-02-01 1996-08-08 Dietl Hans Mittel zur Beeinflussung von Störungen der Knochenbildung
US6287607B2 (en) * 1999-07-19 2001-09-11 Mission Pharmacal Company Potassium calcium citrate compositions and methods therefor
US6599544B2 (en) * 2000-01-26 2003-07-29 American Micronutrients, Inc. Calcium enrichment composition and method for producing the same
BR0114988A (pt) * 2000-10-16 2004-02-03 Pepsico Inc Bebidas suplementadas com cálcio e métodos para fabricá-las
US20030175360A1 (en) * 2002-02-22 2003-09-18 Renzo Luzzatti Symptomatic relief of gastrointestinal disorders
US7507421B2 (en) * 2002-04-30 2009-03-24 Unibar Corporation Hydroxycitric acid salt composition and method of making
US6833146B2 (en) * 2002-07-08 2004-12-21 Unilab Pharmatech, Ltd. Powered beverage mix with rapidly dissolving calcium
US7138151B2 (en) * 2002-11-22 2006-11-21 Unilab Pharmatech, Ltd. Calcium-fortified acidic beverages

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4722847A (en) 1986-05-07 1988-02-02 The Procter & Gamble Company Fruit juice beverages and juice concentrates nutritionally supplemented with calcium
US4871554A (en) 1987-08-12 1989-10-03 Coca-Cola Company Calcium fortified food product
US6680305B1 (en) 1993-06-04 2004-01-20 Biotime, Inc. Physiologically acceptable aqueous solutions and methods for their use
US6319490B1 (en) 1996-02-20 2001-11-20 Smithkline Beecham Plc Liquid oral compositions comprising a calcium compound and an acidulant
US6719963B2 (en) 1996-02-20 2004-04-13 Smithkline Beecham P.L.C. Liquid oral compositions comprising a calcium compound and an acidulant
US6908909B2 (en) 1996-02-20 2005-06-21 Smithkline Beecham Plc Liquid oral compositions comprising a calcium compound and an acidulant
US20040185119A1 (en) 2003-02-26 2004-09-23 Theuer Richard C. Method and compositions for treating gastric hyperacidity while diminishing the likelihood of producing vitamin deficiency

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015120272A1 (en) * 2014-02-06 2015-08-13 University Of Houston System Organic acids as growth inhibitors of pathological calcification and uses thereof
US10285961B2 (en) 2014-02-06 2019-05-14 University Of Houston System Organic acids as agents to dissolve calcium minerals in pathological calcification and uses thereof
WO2016159897A1 (en) * 2015-04-01 2016-10-06 Ay Doğan Potassium citrate suspension
IT202200021258A1 (it) * 2022-10-14 2024-04-14 Neilos S R L “Composizione nutraceutica o farmaceutica per il benessere renale”

Also Published As

Publication number Publication date
AU2006270162B2 (en) 2012-01-12
US20070077314A1 (en) 2007-04-05
AU2006270162A1 (en) 2007-01-25
JP2009514786A (ja) 2009-04-09
EP1922064A4 (en) 2010-12-22
US20100227006A1 (en) 2010-09-09
US8216614B2 (en) 2012-07-10
WO2007011740A3 (en) 2009-04-30
EP1922064A2 (en) 2008-05-21

Similar Documents

Publication Publication Date Title
US8216614B2 (en) Powder mix of potassium calcium citrate for the treatment of kidney stones and osteoporosis
KR101497003B1 (ko) 인산염 흡착제
DK169231B1 (da) Calciumkosttilskudspræparat til opløsning i vand, fremgangsmåde til fremstilling af et sådant, fremgangsmåde til fremstilling af en drikkelig væske baseret derpå, og drikkelig væske, der er egnet som kosttilskud af calcium
AU2008216234B2 (en) Improved stability in vitamin and mineral supplements
CA2587924C (en) Oral compositions for absorption of phosphorus compounds
US8129430B2 (en) Method of reducing phosphate nephropathy in a mammal
US20130189377A1 (en) Compositions
CA2376017C (en) Potassium calcium citrate compositions and methods for production
Porena et al. Prevention of stone disease.
JPS62501846A (ja) 液体食事カルシウム補足
WO2007108712A1 (en) Kit and method for treating or preventing anemia caused by iron deficiency
US20040048925A1 (en) Composition and method for enhancing the bioavailability of calcium and magnesium in dietary supplements and food additives
WO2019201707A1 (de) Stoffgemisch umfassend k-mg-citrat zur verwendung als arzneimittel
RU2527042C1 (ru) Биологически активная добавка к пище для профилактики заболеваний остеопорозом
AU2018327614B2 (en) Composition for calcium supplementation
EP0426098B1 (de) Phosphatbinder zur oralen Verabreichung
US3055805A (en) Process of treating acidosis with t.h.a.m.
US12251400B2 (en) Liquid concentrates of calcium and magnesium
CN102232964B (zh) 治疗泌尿系统结石及高尿酸血症的药物组合物
JP3486755B2 (ja) 高燐血症予防・治療剤
US20200078395A1 (en) Averting complications of pump inhibitor therapy by effervescent calcium magnesium citrate
Abrahams et al. Urinary Stone Inhibitors: Citrate and Magnesium
CA2611659A1 (en) Method for enhancing delivery and uniformity of concentration of dietary ingredients

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
ENP Entry into the national phase

Ref document number: 2008521643

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2006270162

Country of ref document: AU

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2006270162

Country of ref document: AU

Date of ref document: 20060713

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2006787322

Country of ref document: EP