WO2006108430A8 - Nutrient composition comprising green tea polyphenols for treating osteosarcoma - Google Patents

Nutrient composition comprising green tea polyphenols for treating osteosarcoma

Info

Publication number
WO2006108430A8
WO2006108430A8 PCT/EP2005/003775 EP2005003775W WO2006108430A8 WO 2006108430 A8 WO2006108430 A8 WO 2006108430A8 EP 2005003775 W EP2005003775 W EP 2005003775W WO 2006108430 A8 WO2006108430 A8 WO 2006108430A8
Authority
WO
WIPO (PCT)
Prior art keywords
green tea
tea polyphenols
nutrient composition
osteosarcoma
treating osteosarcoma
Prior art date
Application number
PCT/EP2005/003775
Other languages
French (fr)
Other versions
WO2006108430A1 (en
Inventor
Matthias Rath
M Waheed Roomi
Vadim Ivanov
Tatiana Kalinovsky
Aleksandra Niedzwiecki
Original Assignee
Matthias Rath
M Waheed Roomi
Vadim Ivanov
Tatiana Kalinovsky
Aleksandra Niedzwiecki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matthias Rath, M Waheed Roomi, Vadim Ivanov, Tatiana Kalinovsky, Aleksandra Niedzwiecki filed Critical Matthias Rath
Priority to EP05738146A priority Critical patent/EP1874354A1/en
Priority to BRPI0520221-3A priority patent/BRPI0520221A2/en
Priority to CNA2005800498374A priority patent/CN101180080A/en
Priority to PCT/EP2005/003775 priority patent/WO2006108430A1/en
Publication of WO2006108430A1 publication Critical patent/WO2006108430A1/en
Publication of WO2006108430A8 publication Critical patent/WO2006108430A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/32—Manganese; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to the use of a composition comprising an ascorbic acid compound, a L-lysine compound, a L-proline compound, and a polyphenol compound for the preparation of a pharmaceutical composition for treating osteosarcoma. Moreover, the invention further relates to a method of treatment wherein said composition is administered to a subject suffering from osteosarcoma.
PCT/EP2005/003775 2005-04-11 2005-04-11 Nutrient composition comprising green tea polyphenols for treating osteosarcoma WO2006108430A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP05738146A EP1874354A1 (en) 2005-04-11 2005-04-11 Nutrient composition comprising green tea polyphenols for treating osteosarcoma
BRPI0520221-3A BRPI0520221A2 (en) 2005-04-11 2005-04-11 Use of a nutrient composition comprising green tea polyphenols for treating osteosarcoma
CNA2005800498374A CN101180080A (en) 2005-04-11 2005-04-11 Nutritive composition including green tea polyphenol for treating osteosarcoma
PCT/EP2005/003775 WO2006108430A1 (en) 2005-04-11 2005-04-11 Nutrient composition comprising green tea polyphenols for treating osteosarcoma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2005/003775 WO2006108430A1 (en) 2005-04-11 2005-04-11 Nutrient composition comprising green tea polyphenols for treating osteosarcoma

Publications (2)

Publication Number Publication Date
WO2006108430A1 WO2006108430A1 (en) 2006-10-19
WO2006108430A8 true WO2006108430A8 (en) 2007-01-25

Family

ID=35295399

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/003775 WO2006108430A1 (en) 2005-04-11 2005-04-11 Nutrient composition comprising green tea polyphenols for treating osteosarcoma

Country Status (3)

Country Link
EP (1) EP1874354A1 (en)
BR (1) BRPI0520221A2 (en)
WO (1) WO2006108430A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2439804B1 (en) 2009-06-01 2021-07-21 Showa Denko Materials Co., Ltd. Organic electronic material, ink composition containing same, and organic thin film, organic electronic element, organic electroluminescent element, lighting device, and display device formed therewith
EP2976061B1 (en) * 2013-03-18 2019-10-16 Dentalmed Pharm Holding Ltd. Combinations of n-acetyl cysteine derivatives and cranberry polyphenols in compositions and methods for preventing and treating periodontal diseases and peri-implatitis
WO2022124386A1 (en) * 2020-12-07 2022-06-16 L' Oreal Composition comprising ascorbic acid and cyclic amino acid
CN115836666A (en) * 2021-09-20 2023-03-24 上海中医药大学附属龙华医院 Mouse model of in-situ osteosarcoma and pulmonary metastatic tumor and preparation method and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198465A (en) * 1991-06-19 1993-03-30 Dioguardi Francesco S Compositions based on amino acids for preventing and treating precursor deficiencies in the synthesis of collagen
WO2000057875A1 (en) * 1999-03-30 2000-10-05 Purdue Research Foundation Compositions containing tea catechins as cancer specific proliferation inhibitors
DK1195159T3 (en) * 2000-10-09 2006-10-02 Matthias Dr Med Rath Therapeutic combination of ascorbate with lysine and arginine for the prevention or treatment of cancer
RU2301666C2 (en) 2002-01-11 2007-06-27 Маттиас Рат Polyphenol-base pharmaceutical composition possessing nutrient properties and its using in cancer treatment

Also Published As

Publication number Publication date
BRPI0520221A2 (en) 2009-04-22
EP1874354A1 (en) 2008-01-09
WO2006108430A1 (en) 2006-10-19

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