WO2009041786A3 - Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from piper longum for the prevention and treatment of inflammatory disease - Google Patents

Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from piper longum for the prevention and treatment of inflammatory disease Download PDF

Info

Publication number
WO2009041786A3
WO2009041786A3 PCT/KR2008/005722 KR2008005722W WO2009041786A3 WO 2009041786 A3 WO2009041786 A3 WO 2009041786A3 KR 2008005722 W KR2008005722 W KR 2008005722W WO 2009041786 A3 WO2009041786 A3 WO 2009041786A3
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical composition
piper longum
inhibitors
prevention
treatment
Prior art date
Application number
PCT/KR2008/005722
Other languages
French (fr)
Other versions
WO2009041786A2 (en
Inventor
Mun-Chual Rho
Young-Kook Kim
Hyun-Sun Lee
Chang-Duk Jun
Koanhoi Kim
Seung-Woong Lee
Jung Ho Choi
Jae Jun Song
Original Assignee
Korea Res Inst Of Bioscience
Mun-Chual Rho
Young-Kook Kim
Hyun-Sun Lee
Chang-Duk Jun
Koanhoi Kim
Seung-Woong Lee
Jung Ho Choi
Jae Jun Song
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Res Inst Of Bioscience, Mun-Chual Rho, Young-Kook Kim, Hyun-Sun Lee, Chang-Duk Jun, Koanhoi Kim, Seung-Woong Lee, Jung Ho Choi, Jae Jun Song filed Critical Korea Res Inst Of Bioscience
Publication of WO2009041786A2 publication Critical patent/WO2009041786A2/en
Publication of WO2009041786A3 publication Critical patent/WO2009041786A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to a Piper longum extract having prophylactic and therapeutic effects on inflammatory or infectious diseases, and to amide compounds isolated therefrom. In addition, the present invention relates to a pharmaceutical composition for preventing or treating inflammatory or infectious diseases, comprising the Piper longum extract or amide compounds isolated therefrom as an active ingredient.
PCT/KR2008/005722 2007-09-28 2008-09-26 Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from piper longum for the prevention and treatment of inflammatory disease WO2009041786A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2007-0097967 2007-09-28
KR1020070097967A KR100954865B1 (en) 2007-09-28 2007-09-28 Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from Piper longum for the prevention and treatment of inflammatory disease

Publications (2)

Publication Number Publication Date
WO2009041786A2 WO2009041786A2 (en) 2009-04-02
WO2009041786A3 true WO2009041786A3 (en) 2009-05-14

Family

ID=40512029

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2008/005722 WO2009041786A2 (en) 2007-09-28 2008-09-26 Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from piper longum for the prevention and treatment of inflammatory disease

Country Status (2)

Country Link
KR (1) KR100954865B1 (en)
WO (1) WO2009041786A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2647385A4 (en) * 2010-12-02 2014-04-30 Maruzen Pharm Co Ltd Tie2 ACTIVATOR, VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, ANTI-ANGIOGENIC AGENT, AGENT FOR MATURING BLOOD VESSELS, AGENT FOR NORMALIZING BLOOD VESSELS, AGENT FOR STABILIZING BLOOD VESSELS, AND PHARMACEUTICAL COMPOSITION
US20170095520A1 (en) * 2014-03-21 2017-04-06 Dong Wha Pharm. Co., Ltd. A composition for preventing, treating, and improving of voiding dysfunction comprising extract of Piper longum L.
KR101704678B1 (en) * 2014-12-04 2017-02-08 한국생명공학연구원 Composition for preventing or treating parasitization in fishes comprising piper longum extract, or isolated compounds therefrom
KR101704918B1 (en) * 2015-08-24 2017-02-09 동국대학교 경주캠퍼스 산학협력단 Pharmaceutical composition comprising the extracts of mixed crude drugs for the prevention or treatment of the Parkinson's disease
KR20200078803A (en) 2018-12-21 2020-07-02 강릉원주대학교산학협력단 An anti-inflammatory or immunological enhancing composition comprising a Halocynthia aurantium tunic lipids as an active ingredient
KR102652245B1 (en) * 2020-12-11 2024-03-27 경희대학교 산학협력단 Composition for Prophylaxis and Treatment of Osteoporosis Comprising Piperis Longi Fructus Extract

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005298429A (en) * 2004-04-14 2005-10-27 Maruzen Pharmaceut Co Ltd Vascular endothelial type nitric oxide synthase activity promoter
US7081260B2 (en) * 2002-10-29 2006-07-25 Council Of Scientific And Industrial Research α-Glucosidase inhibitors from a natural source

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7081260B2 (en) * 2002-10-29 2006-07-25 Council Of Scientific And Industrial Research α-Glucosidase inhibitors from a natural source
JP2005298429A (en) * 2004-04-14 2005-10-27 Maruzen Pharmaceut Co Ltd Vascular endothelial type nitric oxide synthase activity promoter

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ASHOK K ET AL.: "Investigation toward new lead compounds from medicinally important plants", PURE APPL. CHEM., vol. 77, no. 1, 2005, pages 25 - 40 *
JOCHEN R ET AL.: "Constituents of Chinese Piper species and their inhibitory activity on prostaglandin and leukotriene biosynthesis in vitro", J. ETHNOPHARMACOL., vol. 75, 2001, pages 133 - 139 *
SARVESH KUMAR ET AL.: "Piperine inhibits TNF- a induced adhesion of neutrophils to endothelial monolayer through suppression of NF- K B and I K B kinase activation", EUR. J. PHARMACOL., vol. 575, 3 August 2007 (2007-08-03), pages 177 - 186 *

Also Published As

Publication number Publication date
WO2009041786A2 (en) 2009-04-02
KR20090032600A (en) 2009-04-01
KR100954865B1 (en) 2010-04-28

Similar Documents

Publication Publication Date Title
WO2009041787A3 (en) Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from piper nigrum for the prevention and treatment of inflammatory disease
WO2006096439A3 (en) Pharmaceutical compositions for the treatment and/or prevention of schizophrenia and related diseases
WO2008148074A3 (en) Inhibitors of mtor and methods of treatment using same
WO2008022256A3 (en) Methods and compositions for preventing or treating age-related diseases
WO2007019251A3 (en) Sphingosine kinase inhibitors and methods of their use
WO2007096151A3 (en) Inhibitors of p38-kinase for treatment of pulmonary hypertension
WO2009144555A8 (en) Pyrazolospiroketone acetyl-coa carboxylase inhibitors
WO2007133637A3 (en) Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
WO2007106537A3 (en) Aminoquinolones as gsk-3 inhibitors
EA200900613A1 (en) SPIROKETONE ACETYL-COA-CARBOXYLAS INHIBITORS
WO2009030952A3 (en) Phenylcarboxamide derivatives as inhibitors and effectors of the hedgehog pathway
WO2006096434A3 (en) Pharmaceutical compositions for the treatment and/or prevention of anxiety disorders
WO2009024611A3 (en) 4-benzylaminoquinolines, pharmaceutical compositions containing them and their use
WO2012046030A3 (en) Phosphodiesterase inhibitors
WO2009109613A3 (en) 1-BENZYL-3-HYDROXYMETHYLINDAZOIιE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF DISEASES BASED ON THE EXPRESSION OF MCP-1, CX3CR1
IL193252A0 (en) N-hydroxyacrylamide compounds
EP2142549A4 (en) Adenosine derivatives, method for the synthesis thereof, and the pharmaceutical compositions for the prevention and treatment of the inflammatory diseases containing the same as an active ingredient
WO2008076954A3 (en) Heterocycle compounds and methods of use thereof
WO2009109616A3 (en) 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of mcp-1, cxrl and p40
WO2007128086A3 (en) Novel viral replication inhibitor
WO2009041663A1 (en) Agent for prevention and/or treatment of skin diseases
WO2009035634A3 (en) Cyanoaminoquinolones and tetrazoloaminoquinolones as gsk-3 inhibitors
WO2009109654A8 (en) 1-benzyl-3-hydr0xymethylindaz0le derivatives and use thereof in the treatment of diseases based on the expression of mcp-1, and cx3cr1
WO2008129501A3 (en) Pharmaceutical compositions of duloxetine
WO2009041786A3 (en) Pharmaceutical composition comprising inhibitors of cell adhesion molecule isolated from piper longum for the prevention and treatment of inflammatory disease

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08832968

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08832968

Country of ref document: EP

Kind code of ref document: A2