WO2006098270A8 - オキシメチルホウ素化合物 - Google Patents

オキシメチルホウ素化合物

Info

Publication number
WO2006098270A8
WO2006098270A8 PCT/JP2006/304894 JP2006304894W WO2006098270A8 WO 2006098270 A8 WO2006098270 A8 WO 2006098270A8 JP 2006304894 W JP2006304894 W JP 2006304894W WO 2006098270 A8 WO2006098270 A8 WO 2006098270A8
Authority
WO
WIPO (PCT)
Prior art keywords
compounds
hydroxymethylation
coupling reaction
oxymethylboron
production
Prior art date
Application number
PCT/JP2006/304894
Other languages
English (en)
French (fr)
Other versions
WO2006098270A1 (ja
Inventor
Keigo Tanaka
Satoshi Inoue
Daisuke Ito
Norio Murai
Yosuke Kaburagi
Shuji Shirotori
Shuichi Suzuki
Yoshiaki Ohashi
Original Assignee
Eisai R&D Man Co Ltd
Keigo Tanaka
Satoshi Inoue
Daisuke Ito
Norio Murai
Yosuke Kaburagi
Shuji Shirotori
Shuichi Suzuki
Yoshiaki Ohashi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd, Keigo Tanaka, Satoshi Inoue, Daisuke Ito, Norio Murai, Yosuke Kaburagi, Shuji Shirotori, Shuichi Suzuki, Yoshiaki Ohashi filed Critical Eisai R&D Man Co Ltd
Priority to JP2007508123A priority Critical patent/JP4198742B2/ja
Priority to EP06715617A priority patent/EP1867650B1/en
Priority to US11/886,340 priority patent/US7696347B2/en
Publication of WO2006098270A1 publication Critical patent/WO2006098270A1/ja
Publication of WO2006098270A8 publication Critical patent/WO2006098270A8/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

　本発明は、パラジウム触媒を用いて芳香環をオキシメチル化するカップリング反応において、有機スズ試薬に替わる安全性に優れた化合物であって、その調製の際にシリカゲル等を用いたクロマトグラフィー精製を必要とせず、大量生産に好適な化合物を提供する。さらに既存の手法ではカップリング反応が進行しないまたは反応性が低い芳香環基質に対しても適用可能な化合物を提供する。  
PCT/JP2006/304894 2005-03-14 2006-03-13 オキシメチルホウ素化合物 WO2006098270A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2007508123A JP4198742B2 (ja) 2005-03-14 2006-03-13 オキシメチルホウ素化合物
EP06715617A EP1867650B1 (en) 2005-03-14 2006-03-13 Hydroxymethylboron compounds
US11/886,340 US7696347B2 (en) 2005-03-14 2006-03-13 Oxymethyl boron compounds

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2005070607 2005-03-14
JP2005-070607 2005-03-14
JP2005-294589 2005-10-07
JP2005294589 2005-10-07

Publications (2)

Publication Number Publication Date
WO2006098270A1 WO2006098270A1 (ja) 2006-09-21
WO2006098270A8 true WO2006098270A8 (ja) 2007-08-02

Family

ID=36991612

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2006/304894 WO2006098270A1 (ja) 2005-03-14 2006-03-13 オキシメチルホウ素化合物

Country Status (4)

Country Link
US (1) US7696347B2 (ja)
EP (1) EP1867650B1 (ja)
JP (1) JP4198742B2 (ja)
WO (1) WO2006098270A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5265368B2 (ja) * 2006-09-11 2013-08-14 エーザイ・アール・アンド・ディー・マネジメント株式会社 芳香環を有するフルオロホウ素化合物もしくはその塩、およびそれらを用いた環状エーテル縮合芳香環を有する化合物の製造方法
WO2014160739A2 (en) * 2013-03-27 2014-10-02 Cellmosaic Inc. Trifluoroborate mass spectrometric tags

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858592B2 (en) * 2001-06-29 2005-02-22 Genzyme Corporation Aryl boronic acids for treating obesity
US7514579B2 (en) * 2002-06-13 2009-04-07 Johns Hopkins University Boronic chalcone derivatives and uses thereof

Also Published As

Publication number Publication date
WO2006098270A1 (ja) 2006-09-21
EP1867650A1 (en) 2007-12-19
US7696347B2 (en) 2010-04-13
EP1867650A4 (en) 2010-09-22
US20080242859A1 (en) 2008-10-02
EP1867650B1 (en) 2012-06-27
JPWO2006098270A1 (ja) 2008-08-21
JP4198742B2 (ja) 2008-12-17

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