WO2006091921A3 - Super-sparger microcarrier beads and precision extrusion deposited poly-epsilon-caprolactone structures for biological applications - Google Patents

Super-sparger microcarrier beads and precision extrusion deposited poly-epsilon-caprolactone structures for biological applications Download PDF

Info

Publication number
WO2006091921A3
WO2006091921A3 PCT/US2006/006790 US2006006790W WO2006091921A3 WO 2006091921 A3 WO2006091921 A3 WO 2006091921A3 US 2006006790 W US2006006790 W US 2006006790W WO 2006091921 A3 WO2006091921 A3 WO 2006091921A3
Authority
WO
WIPO (PCT)
Prior art keywords
sparger
epsilon
caprolactone
super
structures
Prior art date
Application number
PCT/US2006/006790
Other languages
French (fr)
Other versions
WO2006091921A2 (en
Inventor
Andrew Darling
Lauren Shor
Wei Sun
Selcuk Guceri
Original Assignee
Univ Drexel
Andrew Darling
Lauren Shor
Wei Sun
Selcuk Guceri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Drexel, Andrew Darling, Lauren Shor, Wei Sun, Selcuk Guceri filed Critical Univ Drexel
Publication of WO2006091921A2 publication Critical patent/WO2006091921A2/en
Priority to US11/842,796 priority Critical patent/US20080020049A1/en
Publication of WO2006091921A3 publication Critical patent/WO2006091921A3/en
Priority to US12/877,818 priority patent/US8735117B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Dispersion Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A microcarrier bead having a porous three-dimensional core having at least 99% interconnected pores and an outer protective layer for growing cells in a bioreactor using higher sparging rates than cells would ordinary withstand. A method of making an artificial scaffold wherein a scaffolding material is extruded into a coolant and thereby creating a porous material.
PCT/US2006/006790 2005-02-25 2006-02-24 Super-sparger microcarrier beads and precision extrusion deposited poly-epsilon-caprolactone structures for biological applications WO2006091921A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US11/842,796 US20080020049A1 (en) 2005-02-25 2007-08-21 Super-sparger microcarrier beads and precision extrusion deposited poly-epsilon-caprolactone structures for biological applications
US12/877,818 US8735117B2 (en) 2005-02-25 2010-09-08 Method for making artificial scaffold having porous three-dimensional body comprising cells

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US65650505P 2005-02-25 2005-02-25
US65625805P 2005-02-25 2005-02-25
US60/656,258 2005-02-25
US60/656,505 2005-02-25

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/842,796 Continuation-In-Part US20080020049A1 (en) 2005-02-25 2007-08-21 Super-sparger microcarrier beads and precision extrusion deposited poly-epsilon-caprolactone structures for biological applications

Publications (2)

Publication Number Publication Date
WO2006091921A2 WO2006091921A2 (en) 2006-08-31
WO2006091921A3 true WO2006091921A3 (en) 2007-12-27

Family

ID=36928102

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/006790 WO2006091921A2 (en) 2005-02-25 2006-02-24 Super-sparger microcarrier beads and precision extrusion deposited poly-epsilon-caprolactone structures for biological applications

Country Status (1)

Country Link
WO (1) WO2006091921A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8828720B2 (en) 2008-03-17 2014-09-09 Agency For Science, Technology And Research Microcarriers for stem cell culture
US9458431B2 (en) 2008-03-17 2016-10-04 Agency For Science, Technology And Research Microcarriers for stem cell culture
JP2011514169A (en) 2008-03-17 2011-05-06 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ Microcarrier for stem cell culture
US8691569B2 (en) 2008-03-17 2014-04-08 Agency For Science, Technology And Research Microcarriers for stem cell culture
EP2408903B1 (en) 2009-03-20 2014-08-06 Agency For Science, Technology And Research Culture of pluripotent and multipotent cells on microcarriers
KR101067827B1 (en) * 2010-03-19 2011-09-27 포항공과대학교 산학협력단 Three-dimensional scaffold and fabrication method for the same
US20160083690A1 (en) * 2013-04-10 2016-03-24 Agency For Science, Technology And Research Microcarriers for stem cell culture and fabrication thereof
EP3623136B1 (en) * 2018-09-14 2023-11-29 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Method for producing three-dimensional hydrogel structures and device for the layerwise building-up of such hydrogel structures
US20220184276A1 (en) * 2019-03-29 2022-06-16 Akira Science Ab Scaffolds for use in tissue engineering and method for preparing scaffolds
CN110124103B (en) * 2019-05-08 2021-07-23 上海交通大学 Active substance sustained-release material system for tissue repair and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5073491A (en) * 1988-12-23 1991-12-17 Hoffman-La Roche Inc. Immobilization of cells in alginate beads containing cavities for growth of cells in airlift bioreactors
US20040010320A1 (en) * 2000-05-11 2004-01-15 Huckle James William Tissue regrafting
WO2004012782A1 (en) * 2002-07-30 2004-02-12 Bionethos Holding Method and device for culturing cells
US20060154365A1 (en) * 2004-08-30 2006-07-13 Anthony Ratcliffe Cultured three dimensional tissues and uses thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5073491A (en) * 1988-12-23 1991-12-17 Hoffman-La Roche Inc. Immobilization of cells in alginate beads containing cavities for growth of cells in airlift bioreactors
US20040010320A1 (en) * 2000-05-11 2004-01-15 Huckle James William Tissue regrafting
WO2004012782A1 (en) * 2002-07-30 2004-02-12 Bionethos Holding Method and device for culturing cells
US20050221485A1 (en) * 2002-07-30 2005-10-06 Augustinus Bader Method and device for culturing cells
US20060154365A1 (en) * 2004-08-30 2006-07-13 Anthony Ratcliffe Cultured three dimensional tissues and uses thereof

Also Published As

Publication number Publication date
WO2006091921A2 (en) 2006-08-31

Similar Documents

Publication Publication Date Title
WO2006091921A3 (en) Super-sparger microcarrier beads and precision extrusion deposited poly-epsilon-caprolactone structures for biological applications
CN101439905B (en) Foaming extrusion molding thermoplastic composite material stuffing for biological treatment of waste water
ATE493264T1 (en) POROUS COMPOSITE MATERIALS AND METHOD FOR THE PRODUCTION AND USE THEREOF
WO2005081970A3 (en) Self-assembling cell aggregates and methods of making engineered tissue using the same
AU1135101A (en) Rapid-prototyping method and apparatus
DE50207943D1 (en) CRYSTALLINE ANTICHOLINERGICUM, METHOD FOR THE PRODUCTION THEREOF AND ITS USE IN THE MANUFACTURE OF A MEDICAMENT
JP4846232B2 (en) Pattern surface formation method
CN106413918B (en) Painting method
CN108476906A (en) A kind of construction method of vertical planting and its application
EP1693075B1 (en) Substrate for tissue regeneration
DE10332093A8 (en) Process for producing an electrochemical cell and the electrochemical cell
DE602005003678D1 (en) MIXED OLANZAPINE SOLVATE, METHOD FOR THE PRODUCTION THEREOF, AND METHOD FOR THE PRODUCTION OF OLANZAPINE FORM I THEREOF
CN111485667A (en) 3d printing customized building block brick and method for building complex wall body by same
DE102006019446A1 (en) Carrier material as growth surface for immobilizing biofilm containing microorganisms in wastewater for biological treatment of wastewater, includes disk-, ring- or unsymmetrical calotte shaped hollow plastic bodies with rough surface
JP3682405B2 (en) Method for producing porous ceramics for planting
CN2880963Y (en) Structure of multifunction ceramsite plate
EP1069128A3 (en) Process for preparing complex lithium salts for use in electrochemical cells
EP2913440B1 (en) Cement-based multilayer assembly that can be used as a biological support for building facades or other structures
CN109796080A (en) A kind of module body for wetland and preparation method thereof and artificial wet land system
EP2386369A3 (en) Method for manufacturing compound bodies
ATE499722T1 (en) METHOD FOR PRODUCING A GAS-TIGHT SOLID ELECTROLYTE LAYER AND SOLID ELECTROLYTE LAYER
EP1139467A3 (en) Active material for anodes in electrochemical cells and process of manufacture thereof
CN107558652A (en) A kind of light thermal-insulation non-light tight concrete building block and its manufacture method
CN112906109B (en) Layered pouring design method for rapidly filling deep cushion layer by utilizing foam concrete
CN219060012U (en) Ecological U-shaped support pile

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 11842796

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 06736169

Country of ref document: EP

Kind code of ref document: A2