WO2006086673A3 - Nucleotide compositions and uses thereof - Google Patents

Nucleotide compositions and uses thereof Download PDF

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Publication number
WO2006086673A3
WO2006086673A3 PCT/US2006/004810 US2006004810W WO2006086673A3 WO 2006086673 A3 WO2006086673 A3 WO 2006086673A3 US 2006004810 W US2006004810 W US 2006004810W WO 2006086673 A3 WO2006086673 A3 WO 2006086673A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
compositions
nucleotide compositions
present
labeled
Prior art date
Application number
PCT/US2006/004810
Other languages
French (fr)
Other versions
WO2006086673A2 (en
Inventor
Stephen Turner
Jonas Korlach
Original Assignee
Pacific Biosciences California
Stephen Turner
Jonas Korlach
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pacific Biosciences California, Stephen Turner, Jonas Korlach filed Critical Pacific Biosciences California
Priority to CA002596495A priority Critical patent/CA2596495A1/en
Priority to EP06734790A priority patent/EP1846758A2/en
Priority to AU2006213692A priority patent/AU2006213692C1/en
Publication of WO2006086673A2 publication Critical patent/WO2006086673A2/en
Publication of WO2006086673A3 publication Critical patent/WO2006086673A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Abstract

The present invention relates to preparation of nucleotide compositions and uses thereof for conducting nucleic acid analyses. The compositions and methods embodied in the present invention are particularly useful for nucleic acid analyses that require high-resolution detection of labeled nucleotides or labeled nucleic acid targets.
PCT/US2006/004810 2005-02-09 2006-02-09 Nucleotide compositions and uses thereof WO2006086673A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002596495A CA2596495A1 (en) 2005-02-09 2006-02-09 Nucleotide compositions and uses thereof
EP06734790A EP1846758A2 (en) 2005-02-09 2006-02-09 Nucleotide compositions and uses thereof
AU2006213692A AU2006213692C1 (en) 2005-02-09 2006-02-09 Nucleotide compositions and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65184605P 2005-02-09 2005-02-09
US60/651,846 2005-02-09

Publications (2)

Publication Number Publication Date
WO2006086673A2 WO2006086673A2 (en) 2006-08-17
WO2006086673A3 true WO2006086673A3 (en) 2009-05-28

Family

ID=36793780

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/004810 WO2006086673A2 (en) 2005-02-09 2006-02-09 Nucleotide compositions and uses thereof

Country Status (5)

Country Link
US (3) US7767394B2 (en)
EP (1) EP1846758A2 (en)
AU (1) AU2006213692C1 (en)
CA (1) CA2596495A1 (en)
WO (1) WO2006086673A2 (en)

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WO2002004680A2 (en) * 2000-07-07 2002-01-17 Visigen Biotechnologies, Inc. Real-time sequence determination
US7211414B2 (en) 2000-12-01 2007-05-01 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
US7668697B2 (en) * 2006-02-06 2010-02-23 Andrei Volkov Method for analyzing dynamic detectable events at the single molecule level
US20090186343A1 (en) * 2003-01-28 2009-07-23 Visigen Biotechnologies, Inc. Methods for preparing modified biomolecules, modified biomolecules and methods for using same
EP1846758A2 (en) * 2005-02-09 2007-10-24 Pacific Biosciences of California, Inc. Nucleotide compositions and uses thereof
US20080091005A1 (en) * 2006-07-20 2008-04-17 Visigen Biotechnologies, Inc. Modified nucleotides, methods for making and using same
US20080241951A1 (en) * 2006-07-20 2008-10-02 Visigen Biotechnologies, Inc. Method and apparatus for moving stage detection of single molecular events
US20080241938A1 (en) * 2006-07-20 2008-10-02 Visigen Biotechnologies, Inc. Automated synthesis or sequencing apparatus and method for making and using same
EP3936857B1 (en) * 2006-09-01 2023-06-21 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
DE102007033737A1 (en) * 2007-07-18 2009-01-22 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. A method for determining a measurement based on single molecule events
WO2009076323A2 (en) * 2007-12-06 2009-06-18 Genalyte Inc. Monitoring enzymatic process
US8252911B2 (en) 2008-02-12 2012-08-28 Pacific Biosciences Of California, Inc. Compositions and methods for use in analytical reactions
US8143030B2 (en) 2008-09-24 2012-03-27 Pacific Biosciences Of California, Inc. Intermittent detection during analytical reactions
US20100036110A1 (en) * 2008-08-08 2010-02-11 Xiaoliang Sunney Xie Methods and compositions for continuous single-molecule nucleic acid sequencing by synthesis with fluorogenic nucleotides
US20100227327A1 (en) * 2008-08-08 2010-09-09 Xiaoliang Sunney Xie Methods and compositions for continuous single-molecule nucleic acid sequencing by synthesis with fluorogenic nucleotides
EP2347247B1 (en) 2008-10-27 2019-06-26 Genalyte, Inc. Biosensors based on optical probing and sensing
EP3266881B1 (en) 2010-11-05 2019-12-25 Genalyte, Inc. Optical analyte detection systems and methods of use
WO2013056241A2 (en) 2011-10-14 2013-04-18 Pacific Biosciences Of California, Inc. Real-time redox sequencing
US8956816B2 (en) 2012-06-05 2015-02-17 Pacific Biosciences Of California, Inc. Methods and compositions for performing analytical operations
EP2891709A4 (en) * 2012-08-30 2016-04-13 Hitachi High Tech Corp Nucleic acid analysis device
US9637782B2 (en) 2012-09-28 2017-05-02 Pacific Biosciences Of California, Inc. Charged triplet-state quenchers for mitigation of photo-induced damage
US9983206B2 (en) 2013-03-15 2018-05-29 The Board Of Trustees Of The University Of Illinois Methods and compositions for enhancing immunoassays
US10302972B2 (en) 2015-01-23 2019-05-28 Pacific Biosciences Of California, Inc. Waveguide transmission
WO2017087696A1 (en) 2015-11-18 2017-05-26 Pacific Biosciences Of California, Inc. Methods and compositions for loading of polymerase complexes
US10870872B2 (en) * 2016-04-04 2020-12-22 President And Fellows Of Harvard College Enzymatic nucleic acid synthesis
US11667951B2 (en) 2016-10-24 2023-06-06 Geneinfosec, Inc. Concealing information present within nucleic acids
US10871485B2 (en) 2018-04-13 2020-12-22 Rarecyte, Inc. Kits for labeling of biomarkers and methods of using the same

Citations (1)

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US6617138B1 (en) * 1998-04-01 2003-09-09 Genpoint As Nucleic acid detection method

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Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
US6617138B1 (en) * 1998-04-01 2003-09-09 Genpoint As Nucleic acid detection method

Also Published As

Publication number Publication date
US7767394B2 (en) 2010-08-03
US20100240045A1 (en) 2010-09-23
AU2006213692C1 (en) 2011-08-04
US20150167074A1 (en) 2015-06-18
EP1846758A2 (en) 2007-10-24
US8927211B2 (en) 2015-01-06
US20060194232A1 (en) 2006-08-31
AU2006213692B2 (en) 2011-03-24
AU2006213692A1 (en) 2006-08-17
CA2596495A1 (en) 2006-08-17
WO2006086673A2 (en) 2006-08-17

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