WO2006060225A3 - Processus destine a la synthese asymetrique d'hexahydropyrimido[1,2-a] azepine-2-carboxamides et de composes correspondants - Google Patents
Processus destine a la synthese asymetrique d'hexahydropyrimido[1,2-a] azepine-2-carboxamides et de composes correspondants Download PDFInfo
- Publication number
- WO2006060225A3 WO2006060225A3 PCT/US2005/042211 US2005042211W WO2006060225A3 WO 2006060225 A3 WO2006060225 A3 WO 2006060225A3 US 2005042211 W US2005042211 W US 2005042211W WO 2006060225 A3 WO2006060225 A3 WO 2006060225A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- carboxamides
- hexahydropyrimido
- azepine
- related compounds
- asymmetric synthesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63032204P | 2004-11-23 | 2004-11-23 | |
US60/630,322 | 2004-11-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006060225A2 WO2006060225A2 (fr) | 2006-06-08 |
WO2006060225A3 true WO2006060225A3 (fr) | 2006-10-12 |
Family
ID=36216789
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/042211 WO2006060225A2 (fr) | 2004-11-23 | 2005-11-18 | Processus destine a la synthese asymetrique d'hexahydropyrimido[1,2-a] azepine-2-carboxamides et de composes correspondants |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2006060225A2 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2662419A1 (fr) * | 2006-09-15 | 2008-03-20 | Stefan Abrecht | Methode de preparation de derives de pyrido[2,1-a]isoquinoline par hydrogenation asymetrique catalytique d'une enamine |
WO2008123067A1 (fr) * | 2007-03-19 | 2008-10-16 | Takeda Pharmaceutical Company Limited | Procédé d'hydrogénation asymétrique d'allyl amine |
PE20110344A1 (es) * | 2008-10-06 | 2011-06-22 | Merck Sharp & Dohme | Derivados de etanodiamida como inhibidores de la integrasa del vih |
US9227901B2 (en) * | 2012-07-05 | 2016-01-05 | Abbvie Inc. | Process for preparing bicyclic amine derivatives |
WO2014008636A1 (fr) * | 2012-07-11 | 2014-01-16 | Merck Sharp & Dohme Corp. | Composés macrocycliques en tant qu'inhibiteurs de l'intégrase du vih |
CN115677579B (zh) * | 2022-11-02 | 2024-05-24 | 上海药坦药物研究开发有限公司 | 四氢罂粟碱及其中间体的制备方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1386901A1 (fr) * | 2002-07-30 | 2004-02-04 | Takasago International Corporation | Procédé pour la préparation d'un béta acide aminé optiquement actif |
WO2004058757A1 (fr) * | 2002-12-27 | 2004-07-15 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa | Tetrahydro-4h-pyrido[1,2-a]pyrimidines et composes associes utilises en tant qu'inhibiteurs de l'integrase du vih |
WO2005061501A2 (fr) * | 2003-12-12 | 2005-07-07 | Merck & Co., Inc. | Procede de preparation de hexahydropyrimido[1,2-a]azepine-2-carboxylates et composes connexes |
-
2005
- 2005-11-18 WO PCT/US2005/042211 patent/WO2006060225A2/fr active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1386901A1 (fr) * | 2002-07-30 | 2004-02-04 | Takasago International Corporation | Procédé pour la préparation d'un béta acide aminé optiquement actif |
WO2004058757A1 (fr) * | 2002-12-27 | 2004-07-15 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa | Tetrahydro-4h-pyrido[1,2-a]pyrimidines et composes associes utilises en tant qu'inhibiteurs de l'integrase du vih |
WO2005061501A2 (fr) * | 2003-12-12 | 2005-07-07 | Merck & Co., Inc. | Procede de preparation de hexahydropyrimido[1,2-a]azepine-2-carboxylates et composes connexes |
Non-Patent Citations (2)
Title |
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RINGWALD M ET AL: "ASYMMETRIC THERMAL TRANSFORMATION, A NEW WAY TO ENANTIOPURE BIPHENYL-BRIDGED TITANOCENE AND ZIRCONOCENE COMPLEXES: EFFICIENT CATALYSTS FOR ASYMMETRIC IMINE HYDROGENATION", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 121, no. 7, 1999, pages 1524 - 1527, XP000962051, ISSN: 0002-7863 * |
YI HSIAO ET AL: "Highly Efficient Synthesis of beta-Amino Acid Derivatives via Asymmetric Hydrogenation of Unprotected Enamines", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 126, no. 32, 21 July 2004 (2004-07-21), pages 9918 - 9919, XP002339712, ISSN: 0002-7863 * |
Also Published As
Publication number | Publication date |
---|---|
WO2006060225A2 (fr) | 2006-06-08 |
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