New! View global litigation for patent families

WO2006044581A2 - Single-use transurethral needle ablation device - Google Patents

Single-use transurethral needle ablation device

Info

Publication number
WO2006044581A2
WO2006044581A2 PCT/US2005/036906 US2005036906W WO2006044581A2 WO 2006044581 A2 WO2006044581 A2 WO 2006044581A2 US 2005036906 W US2005036906 W US 2005036906W WO 2006044581 A2 WO2006044581 A2 WO 2006044581A2
Authority
WO
Grant status
Application
Patent type
Prior art keywords
device
ablation
needle
energy
catheter
Prior art date
Application number
PCT/US2005/036906
Other languages
French (fr)
Other versions
WO2006044581A3 (en )
Inventor
Mark A. Christopherson
Shahn S. Sage
John M. Swoyer
Ahmed Elmouelhi
Original Assignee
Medtronic, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1477Needle-like probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00238Type of minimally invasive operation
    • A61B2017/00274Prostate operation, e.g. prostatectomy, turp, bhp treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00505Urinary tract
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00547Prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1475Electrodes retractable in or deployable from a housing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/08Accessories or related features not otherwise provided for
    • A61B2090/0803Counting the number of times an instrument is used

Abstract

A one-piece, single-use disposable device (10) for transurethral needle ablation (TUNA) of prostate tissue to alleviate BPH is disclosed. The device may include a flexible catheter tip (60) including a rigid core (62) and a flexible tip (64). The device may also include a single use lockout (80) to help ensure that the device is used to perform only one ablation procedure on a single patient. The device may further include a simplified needle deployment mechanism (100) and/or an automatic needle retraction mechanism (150).

Description

SINGLE-USE TRANSURETHRAL NEEDLE ABLATION

FIELD OF THE INVENTION The invention relates generally to prostate treatment and, more particularly, to techniques for transurethral treatment of benign prostatic hypertrophy (BPH).

BACKGROUND

Benign prostatic hypertrophy or hyperplasia (BPH) is one of the most common medical problems experienced by men over 50 years old. Urinary tract obstruction due to prostatic hyperplasia has been recognized since the earliest days of medicine. Hyperplastic enlargement of the prostate gland often leads to compression of the urethra, resulting in obstruction of the urinary tract and the subsequent development of symptoms including frequent urination, urgency, decrease in urinary flow, nocturia, pain, discomfort, and dribbling.

One surgical procedure for treating BPH is transurethral needle ablation (TUNA). The TUNA technique involves transurethral delivery of an electrically conductive needle to the prostate site. The needle penetrates the prostate in a direction generally perpendicular to the urethral wall, and delivers electrical current to ablate prostate tissue. The electrical current heats tissue surrounding the needle tip to destroy prostate cells, and thereby create a lesion within the prostate gland. The destroyed cells may be absorbed by the body, infiltrated with scar tissue or become non-functional.

U.S. Patent No. 5,807,309 to Lundquist et al. discloses an example of a transurethral ablation device that includes a disposable needle assembly. U.S. Patent No. 5,964,756 to McGaffigan et al. describes another transurethral ablation needle device having a reusable handle and a replaceable cartridge assembly. Table 1 below lists documents that disclose devices for transurethral ablation of prostate tissue. TABLE l

All documents listed in Table 1 above are hereby incorporated by reference herein in their respective entireties. As those of ordinary skill in the art will appreciate readily upon reading the Summary of the Invention, Detailed Description of the Preferred Embodiments and Claims set forth below, many of the devices and methods disclosed in the patents of Table 1 may be modified advantageously by using the techniques of the present invention.

SUMMARY

The present invention is directed to a one-piece, disposable device and method for transurethral needle ablation (TUNA) of prostate tissue to alleviate BPH. The device is designed to perform one ablation procedure on a single patient and then be discarded. The device may include a flexible catheter tip including a rigid core and a flexible tip. The flexible tip provides increased comfort for the patient during insertion of the catheter into the urethra. The rigid core provides support to the flexible tip, and is open ended for delivery of fluid to cool the urethra. The device may also include a single use lock-out to help ensure that the device is used to perform only one ablation procedure on a single patient. The device may further include a simplified needle deployment mechanism and/or an automatic needle retraction mechanism.

Various embodiments of the present invention provide solutions to one or more problems existing in the prior art with respect to the ablation of prostate tissue. One problem, for example, is the requirement that a TUNA device, like most reusable medical devices, must be sterilized before it can be used to perform an ablation procedure on another patient. Sterilization introduces an unavoidable, fixed time delay between ablation procedures. To avoid this delay, the physician must either stock multiple TUNA devices so that procedures can be performed on several patients in sequence, or reduce the number of procedures performed in a given period of time to allow for sterilization of the TUNA device. Another problem encountered with TUNA therapy is discomfort for the patient during insertion of the catheter within the urethra. At the beginning of an ablation procedure, the TUNA catheter is inserted at the tip of the penis and traverses the length of the urethra until the distal end of the catheter is properly positioned with respect to the target tissue. Even with the various types of anesthesia used during a typical TUNA procedure, including both local and topical anesthesias, insertion of the catheter into the urethra may be uncomfortable for many patients.

Another problem may arise with TUNA devices having a disposable catheter cartridge and a reusable handle. This type of device suffers from the same sterilization problem described above. Although the catheter cartridge is designed for single-use and is disposable, the reusable handle still requires sterilization between procedures. In addition, assembly of the cartridge and the handle is required before the procedure can be performed. Users may have difficulty assembling the device, or may fail to properly assemble the device. Either case results in an inefficient procedure for both the physician and the patient. Even when there are no difficulties with assembly, this type of device requires a certain amount of pre-procedure preparation time for assembling the catheter cartridge and the handle.

Another problem with conventional TUNA devices is the need to maintain the device itself. By their very nature, reusable devices intended for long term use require a certain amount of upkeep to keep them in proper working order. Some of this maintenance can be done at the hospital, clinic or other location close to the physician.

Other times, the device must be returned to the manufacturer. For example, in addition to scheduled, periodic maintenance, the devices may sometimes need to be returned to the manufacturer for more intensive maintenance, such as when a device failure occurs. In any event, some conventional TUNA devices will at times be unavailable due to maintenance. Physicians may therefore have to stock a greater number of TUNA devices to ensure a desired patient throughput, or reduce the number of procedures performed in a given amount of time. Another problem arises from the nature of the TUNA procedure itself. In a typical TUNA procedure, multiple ablations may be performed at different locations throughout the prostate. After ablation of tissue in one location is complete, the physician may retract the needles into the catheter, rotate and reposition the catheter within the urethra, and deploy the needles at a different tissue location. At times, however, the physician may fail to fully retract the needles before repositioning the catheter. For example, the physician may attempt to but inadvertently fail to fully retract the needles or may forget to retract the needles entirely before attempting to reposition the device within the urethra. When the catheter is repositioned within the urethra, the still fully or partially deployed needles may cause damage to the prostate and/or the urethra, as well as result in increased patient pain and longer recovery times.

Various embodiments of the present invention may posses one or more features to solve at least one of the foregoing problems. For example, the present invention overcomes at least some of the disadvantages of the foregoing procedures by providing a one-piece, disposable device for transurethral needle ablation (TUNA) of prostate tissue to alleviate BPH. The device may be designed to perform one ablation procedure on a single patient and then be discarded. The device may be constructed of mostly plastic parts. The device may include a single use lock-out to help ensure that the device is not inadvertently used on more than one patient. The device may also include a flexible catheter tip. In addition, the device may include a simplified needle deployment mechanism. As a further feature, the device may include an automatic retraction mechanism.

The invention also provides a transurethral ablation procedure embodied by a method for use of the ablation device described above. The method involves, for example, inserting a distal end of a transurethral needle ablation catheter into a urethra of a male patient, deploying at least one ablation needle, applying ablation energy via the ablation needle, withdrawing the catheter from the urethra, and disposing of the transurethral needle ablation device after the ablation procedure is complete.

In comparison to known implementations of transurethral needle ablation, various embodiments of the present invention may provide one or more advantages. Because the device is designed for one-time use, sterilization is not required. This may minimize preparation time between procedures as well as result in higher patient throughput. In addition, the one-piece design of the device means that no pre-procedure assembly is required, further reducing preparation time. Furthermore, time spent maintaining the device may be reduced or eliminated as the device is used only once and then discarded. In addition, because the device may include a simplified design constructed of mostly plastic parts, the resulting TUNA device may be more reliable, easier to manufacture, lighter in weight and easier for the physician to operate and maneuver. These features may result in a transurethral ablation device that enables the physician to perform faster, more accurate, and more efficient TUNA procedures.

As another advantage, the flexible catheter tip may provide increased patient comfort during insertion of the catheter into the urethra. As another advantage, the single use lockout helps to ensure that the device is used on only a single patient. In this way, the patient receives the benefit of a dedicated TUNA device, increasing procedural safety.

As yet another advantage, the simplified needle deployment mechanism may result in a TUNA device that is more reliable, easier to manufacture, lighter and easier for the physician to maneuver. As yet another advantage, the automatic needle retraction mechanism helps ensure full retraction of the needles. The automatic needle retraction feature thus may increase the safety of the procedure by reducing the likelihood of inadvertent failure to fully retract the needles before the catheter is repositioned within or withdrawn from the urethra, thus reducing the likelihood of damage to the prostate or the urethra, and the associated increases in patient pain and recovery time. Thus, the invention can reduce the complexity of the ablation procedure, while increasing efficiency, convenience and safety. The invention can also result in a procedure in which the risk of damage to the urethra, patient pain and recovery times are minimized, thus further promoting patient safety and procedural efficacy.

The above summary of the present invention is not intended to describe each embodiment or every embodiment of the present invention or each and every feature of the invention. Advantages and attainments, together with a more complete understanding of the invention, will become apparent and appreciated by referring to the following detailed description and claims taken in conjunction with the accompanying drawings. The details of one or more embodiments of the invention are set forth in the accompanying drawings and the description below. Other features and advantages of the invention will be apparent from the description and drawings, and from the claims. BRIEF DESCRIPTION OF DRAWINGS

FIG. 1 is a schematic diagram illustrating a device for transurethral ablation of prostate tissue in accordance with the invention. FIG. 2 illustrates the distal end of the device of FIG. 1 positioned to perform an ablation procedure within the urethra of a patient.

FIGS. 3A and 3B are side and bottom views, respectively, of the catheter tip at the distal end of the catheter of the device of FIG. 1.

FIG. 4 is a block diagram of the device of FIG. 1. FIG. 5 A is a block diagram of the single-use lock out feature for the device of FIG.

1; FIG. 5B is a block diagram of the ablation energy generator.

FIGS. 6A-6J are diagrams illustrating the design and operation of the needle deployment mechanism of the device of FIG. 1.

FIG. 7 is a diagram showing an automatic retraction mechanism for the device of FIG. 1.

DETAILED DESCRIPTION

FIG. 1 is a schematic diagram illustrating a device 10 for transurethral needle ablation (TUNA) of prostate tissue. In one embodiment, device 10 is a one-piece, single use disposable device. The device may also include other features that will be apparent from this description.

As shown in FIG. 1, device 10 includes a housing 12 and a catheter 14 extending from the housing. A trigger-like lever 18 is actuated to advance electrically conductive ablation needles 30 from a distal end 16 of catheter 14. Device 10 may further include an endoscope 20 coupled to an endoscopic transducer (not shown) that extends along the length of catheter 14. Endoscopic viewfinder provides visualization of the urethra to assist the physician in positioning the distal end 16 and ablation needles 30 with respect to the target prostate tissue.

A fluid delivery tube 28 may be coupled to a fluid delivery lumen (not shown) that extends along the length of catheter 14 to deliver fluid to distal end 16. A proximal end of fluid delivery tube 28 is coupled to a fluid delivery device 40 that includes a reservoir containing a fluid and hardware to transmit the fluid to fluid delivery tube 28. For example, fluid delivery device 40 may include a pump, a syringe, or other mechanism to transmit the fluid. In some embodiments, the fluid may be an electrically conductive fluid such as saline.

An ablation current cable 26 is coupled to an electrical conductor that extends along the length of catheter 14 to needles 30. A proximal end of cable 26 is coupled to an ablation energy generator 50. An on/off switch 36 allows the physician to control power to the device 10. In the embodiment shown in FIG. 1, on/off switch 36 is located on ablation current cable 26. Ablation energy generator 50 may include a controller 52 that controls the ablation energy delivered to electrically conductive needles 30. Controller 52 may also control other aspects of the ablation procedure. Controller 52 may include one or more microprocessors, digital signal processors (DSPs), application-specific integrated circuits (ASICs), field-programmable gate arrays (FPGAs), or other equivalent logic circuitry. The image from endoscopic viewfinder 20 and other pertinent information concerning the ablation procedure may be acquired and processed via the ablation energy generator 50 and displayed on an associated graphical user interface 54 for view by a physician.

Ablation energy from ablation energy generator 50 is applied to the prostate tissue via ablation needles 30. Needles 30 may be constructed of a highly flexible, conductive metal such as nickel-titanium alloy, tempered steel, stainless steel, beryllium-copper alloy and the like. Nickel-titanium and similar highly flexible, shaped memory alloys are preferred. The needles 30 may be unipolar or bipolar. In the unipolar embodiment, ablation energy flows through each needle 30 while ground pads attached to the patient's skin act as return electrodes. In the bipolar embodiment, ablation energy flows between the needles 30 and through the surrounding prostate tissue to create a lesion. In another embodiment, a single needle 30 may be used. In that case, the ablation energy may flow between two electrodes carried by the single needle, or between the needle and a ground pad attached to the patient's skin, for example.

Device 10 may be configured to provide several alternative depths to which the needles may be deployed. Needle depth selector 22 allows the physician to control the amount that the needles extend from the distal end 16 of catheter 14 when deployed. As used herein, "needle depth" refers to the distance that a needle extends from the distal end 16 of catheter 14. Needle depth is measured from the needle exit port (see FIG. 4A, for example) at the distal end 16 of catheter 14 to the tip of a needle 30. In the embodiment shown in FIG. 1, the available needle depths are 12mm, 14mm, 16mm, 18mm, 20mm and 24mm, although many other needle depths could be provided and the invention is not limited in this respect. The electrical ablation current produced by ablation energy generator 50 and delivered by needles 30 may be selected to provide pulsed or sinusoidal waveforms, cutting waves, or blended waveforms that are effective in producing the resistive/ohmic/thermal heating which kills cells within the target tissue. In addition, the electrical current may include ablation current followed by current sufficient to cauterize blood vessels. The characteristics of the electrical ablation current are selected to achieve significant cell destruction within the target tissue. The electrical ablation current may comprise radio frequency (RJF) current producing power in the range of approximately 5 to 300 watts, and more preferably 5 to 50 watts, and can be applied for approximately 15 seconds to 3 minutes. If electrocautery is also provided via needles 19, then ablation energy generator 50 also may generate electrocautery waveforms.

FIG. 2 shows a side view of the distal end 16 of the device of FIG. 1 inserted within a urethra 42 of a patient. Although an exemplary two-needle system is shown in FIG. 2, it shall be understood that single needle systems could also be used and that the invention is not limited in this respect. In addition, three, four or other multiple needle configurations could also be used without departing from the scope of the present invention.

In operation, a physician introduces catheter 14 into urethra 36 of a male patient, and advances the catheter so that distal end 16 is deployed adjacent to a prostate lobe, such as prostate lobe 44. Endoscopic viewfinder 20 may aid in positioning distal end 16 of catheter 14 relative to the prostate lobes.

The physician may actuate lever 18 (see FIG. 1) to drive needles 30 through the wall of urethra 42 and into prostate lobe 44. In some embodiments, catheter 14 may carry multiple pairs of ablation needles on opposite sides of the catheter to simultaneously access more than one prostate lobe. Prior to activation of ablation energy generator 50 to deliver ablation current to needles 30, fluid delivery device 40 (see FIG. 1) may be activated to deliver fluid to the target tissue site within the urethra proximate prostate lobe 44. The fluid functions to cool the urethra during the ablation procedure. The fluid may be sufficiently viscous to provide a controllable flow within catheter 14 and out of distal end 16 of catheter 14. Fluid delivery device 40 may be activated to deliver the fluid before, during and/or after the ablation procedure. The fluid may also be a conductive fluid in embodiments where fluid is delivered via the needles or other means into the prostate tissue to create a wet electrode.

Upon penetration of needles 30 into prostate lobe 44 and delivery of the fluid, the needles 30 deliver ablation energy from ablation energy generator 50 to ablate the target tissue within the prostate lobe. After completion of an ablation, the physician may fully retract the needles back into the catheter, and rotate or otherwise reposition the catheter within the urethra to create additional lesions within the same prostate lobe 44, or to access and ablate another prostate lobe, if desired. After the completion of the ablation procedure, the needles are fully retracted into the catheter and the device is withdrawn from the urethra. In an embodiment where device 10 is a single use, disposable device, device 10 may then be discarded.

FIG. 3 A shows a side view and FIG. 3B shows a bottom view of catheter tip 60 positioned at the distal end 16 of catheter 14 for the device of FIG. 1. Catheter tip 60 includes a rigid core 62 and a flexible tip 64. Flexible tip 64 is preferably fabricated of a suitable flexible material and provides increased patient comfort during insertion of catheter 14 into the urethra of the patient. Rigid core 62 provides support for the flexible tip 64 and also provides support for guide tubes 66. Catheter tip 60 also includes support structures 72 that serve to further support flexible tip 64 during insertion of the catheter into the urethra.

In one embodiment, rigid core 62 is fabricated from a material chosen to provide sufficient rigidity to adequately support guide tubes 66 and to provide support for flexible tip 64 during insertion into the urethra. Examples of suitable materials with which to construct rigid core 62 may include materials that are sufficiently rigid to provide support to the flexible tip during insertion into the urethra and to adequately support guide tubes 66. Other properties that may be considered are the ability to withstand a vacuum (for sterilization of the device at the time of manufacture), the ability to withstand the high temperatures experienced during an ablation procedure, biocompatibility and resistance to deformation. To provide sufficient rigidity, a material having a Shore A hardness of at least 70 may be used. In one embodiment, rigid core 62 is constructed using a thermoplastic elastomer, such as Versaflex™ OM 1060, available from GLS Corporation of McHenry, IL.

In the embodiment shown in FIG. 3A, flexible tip 64 is substantially elbow-shaped. The flexibility and elbow shape of flexible tip may provide for more comfortable insertion of the catheter into the urethra. The material with which to construct flexible tip 64 may thus be chosen to be sufficiently flexible to allow for this more comfortable insertion. Other properties that may be considered when choosing a material with which to construct flexible tip 64 are the ability to withstand vacuum conditions, the ability to withstand high temperatures experienced during an ablation procedure, biocompatibility and resistance to deformation. To provide sufficient flexibility, a material having a Shore A hardness in the range of, for example, between 20 and 90, and preferably between 30 and 70, may be used. Examples of such materials include silicone, thermoplastic elastomers, and other types of medical grade rubbers. In one embodiment, flexible tip 60 may be constructed using a Versaflex™ thermoplastic elastomer, available from GLS Corporation of McHenry,

Illinois.

Rigid core 62 provides an open end 63 through which fluid may be delivered to cool the urethra during the course of the ablation procedure. The fluid may be delivered via fluid delivery tube 28 (see FIG. 1) that connects to a second fluid delivery tube (not shown in FIGS. 3A-3B) extending through the length of catheter 14. The fluid travels out the open end 63 of rigid core 62. A notch 74 on the side of needle exit from the catheter 14 assists in spreading the fluid to cool the urethra during the ablation procedure. Notch 74 may extend along at least a portion of the length of flexible tip 64 and may be substantially V-shaped to assist with spreading of the cooling fluid. Catheter 14 includes guide tubes 66A and 66B extending from the proximal to near the distal end of rigid core 62. Needle exit ports 68A and 68B are formed in the wall of rigid core 62 by the guide tubes 66A and 66B, respectively. Needles 30A and 3OB (needle 30B not shown) may be disposed adjacent one another in a substantially side-by-side relationship. Each needle 30A and 30B has a different insertion point into the prostate tissue, resulting in two different needle "sticks" through the prostate tissue. Each needle

30A and 3OB is surrounded by an insulative sheath 38A and 38B, respectively. Insulative sheaths 38A and 38B may extend at least partially into the prostate upon deployment of the needle to protect the urethra from undesired ablation of the urethral wall.

Push rods (not shown) are connected at their proximal end to a needle deployment mechanism 100 (see FIGS. 6A-6J) for deploying the needles 30 and their corresponding sheaths 38. For example, the push rods may be operationally connected to lever 18 via needle deployment mechanism 100 for deploying the needles 30 out of the catheter tip and into the prostate tissue. The push rods serve to transfer the mechanical motion of lever 18 and thus "push" their respective needle 30 and sheath 38 out of the respective exit port 68 of the guide tube 66 and into the prostate tissue. In one embodiment, the needles 30 may be inserted into the same prostate lobe such that a larger lesion may be created within the prostate lobe during the ablation procedure. In another embodiment, the needles 30 may be arranged for simultaneous insertion into different prostate lobes.

Once deployed from the distal end 16 of the catheter 14, the needles 30A and 3OB may be physically spaced apart such that they create a sufficiently large ablation zone. At the same time, the needles may be spaced sufficiently close so that they both penetrate the same prostate lobe. In addition, device 10 may be configured to provide several alternative needle depths. The needle depth is indicated in FIG. 3A by reference numeral 56. As used herein, "needle depth" refers to the distance that a needle is extended from the distal end 16 of catheter 14. Needle depth 56 is measured from the needle exit port at the distal end 16 of catheter 14 to the tip of the needle 30. In one embodiment, each needle 3OA and 30B may have a total length in the range of approximately 12 - 22 millimeters, which may be adjustable by the physician as described above with respect to FIG. 1, or which may be fixed in some embodiments. However, any other appropriate needle depths could also be used, and the invention is not limited in this respect. Insulative sheaths 38A and 38B may extend at least partially into the prostate upon deployment of the needle to protect the urethra from undesired ablation of the urethral wall. During needle insertion, needle deployment mechanism advances needles 30 and their respective sheaths 38 through the wall of the prostate and into the prostate tissue. In one embodiment, sheaths 38 are initially advanced to a depth of approximately 8-10 millimeters to ensure that the sheath remains partially extended into the prostate once the needles are fully deployed. This avoids the tenting effect that may be encountered when the needles are first inserted into the prostate tissue. After the sheath is advanced to the 8- 10 millimeter depth, needle deployment mechanism 100 retracts the sheath back to a depth where it remains to protect the urethra during the ablation procedure. The "sheath depth" 58 is indicated in FIG. 3 A. In one embodiment, for example, sheaths 38 extend approximately 6 millimeters from the needle exit ports 68 during application of ablation energy. However, it shall be understood that a 6 millimeter sheath depth is but one example of a sheath depth, and that other sheath depths could also be used. In another embodiment, sheaths 38 may be advanced directly to the desired depth, for example, 6 millimeters, without the initial overextension and subsequent partial retraction.

Thermocouple 34 is positioned on the outside wall of the distal end of guide tube 66. Thermocouple 34 may be welded or otherwise attached to the outside wall of the distal end of guide tube 66 and positioned near exit port 68. In this position, thermocouple 34 may accurately measure the temperature of the urethra during the ablation procedure while being protected from movement of the needle and the sheath during deployment and retraction of the needles 30. Accurate temperature sensing may be provided due to the thermally conductive properties of the stainless steel or other material used to construct guide tubes 66. Heat generated in the urethra during an ablation procedure may be thermally conducted through the guide tube where it may be sensed by thermocouple 34. Ablation energy generator 50 receives this temperature information via connector 35 and ablation current cable 26. Controller 42 analyzes the temperature information and may control the application of ablation energy to ensure that the urethral temperature remains at a safe level. In one embodiment, a single thermocouple 34 attached to one of the guide tubes, for example, either one of guide tubes 66A or 66B, provides the temperature information. In another embodiment, two thermocouples, one associated with each guide tube 66A and 66B may be included to provide additional temperature sensing or to provide redundancy in case of hardware failure.

FIG. 4 shows a block diagram of a TUNA device 10 such as that shown in FIG. 1. On/off switch 36 on ablation current cable 26 allows a physician to electrically connect ablation energy generator 50 to device 10 for communication of status information with controller 52 and for delivery of ablation current to the electrically conductive needles 30. Once inside device 10, cable 26 may include three separate connection lines; line 26A allows controller 52 to query single-use lockout to obtain device usage information to help ensure that device 10 is not used on more than one patient, line 26B delivers ablation energy from ablation energy generator 50 to the electrically conductive needles 30, and line 26C allows controller 52 to receive temperature information from thermocouple 34. Needle depth selector 22 allows a physician to select a desired needle depth from among several available needle depths. Needle deployment mechanism 100 advances needles 30 out of the distal end of the catheter and into the target tissue, controlling the advancement to the desired needle depth as determined by needle depth selector 22. Needle deployment mechanism 100 is described in more detail with respect to FIGS. 6A- 6J. Needle retraction mechanism 150 automatically fully retracts needles 30 back into the catheter so that device 10 may be repositioned within the urethra to ablate a different target tissue site or so that the catheter may be safely withdrawn from the urethra upon completion of the ablation procedure. Needle retraction mechanism 150 is described in more detail with respect to FIG. 7.

Thermocouple 34 is positioned on an outer wall of a guide tube at the distal end of catheter near the exit ports for needles 30 (see FIG. 3A). Thermocouple 34 measures the temperature of the surrounding tissue to prevent overheating of the tissue during an ablation. The ablation energy generator receives temperature information from the thermocouple along ablation current cable line 26C. Controller 52 (see FIG. 1) may control application of the ablation energy based on the received temperature information, for example, to prevent overheating and burning of the target tissue or the urethra. Single-use lockout 80 helps to ensure that the device 10 is not inadvertently used on more than one patient. Specifically, single-use lockout stores information concerning usage of the device 10. This device usage information may then be used to determine whether the device has been previously used on a different patient. For example, single- use lockout 80 may store usage information concerning, for example, a total amount of time elapsed since the first delivery of ablation energy (a total time of use), a total amount of time that device 10 has delivered ablation energy (a total ablation time), and/or a count of a total number of times that device 10 has delivered ablation energy (an ablation count). FIG. 5 A shows a block diagram of single-use lockout 80. Single-use lockout 80 is essentially a device specific memory chip for storing device usage information. This device usage information may be used to determine whether a device has been previously used on another patient. Single-use lockout 80 may include, for example, a read/write once memory 86 and a read/writable memory 88. Both read/write once memory 86 and read/writable memory 88 may be nonvolatile memory so that they do not require power to maintain the stored device usage information.

FIG. 5B shows a block diagram of ablation energy generator 50. Ablation energy generator includes controller 52, ablation energy delivery unit 53, counter 82 and timer 84. Counter 82 and timer 84 may be used to monitor device usage information, which is then written to single-use lockout 80 located within device 10. The monitored device usage information may include, for example, an absolute calendar time of first use (e.g., the actual calendar time, including day, month, and year as well as the hour, minute and second at which ablation energy is first applied to the patient) a total elapsed calendar time of use (e.g., the total amount of time elapsed since the absolute calendar time of first use), a total amount of time that ablation energy is delivered, a count of a total number of times that ablation energy is delivered, and/or some other appropriate parameter which may indicate whether the device has been previously used on a different patient.

Timer 84 may include a real-time clock that may be used to monitor the time of first use, and the total elapsed time of use. Timer 84 may also monitor the total amount of time that ablation energy is delivered to needles 30. Counter 82 may count the number of times that ablation energy is delivered to the needles 30. Controller 52 may write the monitored device usage information to single-use lockout 80 via line 26B for storage in one of read/write once memory 86 or read/writable memory 88. For example, the absolute calendar time of first use may be stored in read/write once memory 86. Storing the absolute calendar time of first use in a memory that may not later be overwritten may prevent unauthorized tampering with device 10 and thus further help to ensure that device 10 is not used on more than one patient. The total elapsed calendar time of use, the total amount of time that ablation energy is delivered and the counted number of times that ablation energy is applied may be stored in read/writable memory 88. Storing this information in read/writable memory 88 allows controller 52 to periodically update the information throughout the course of the ablation procedure.

When device 10 is powered on via switch 36, controller 52 may query single-use lockout 80 along line 26B to obtain the stored device usage information. Controller 52 may then control delivery of ablation energy by ablation energy delivery unit 53 to the needles 30 based on the stored device usage information. For example, controller 52 may enable delivery of ablation energy if the stored device usage information indicates that device 10 has not been used on a previous patient. On the other hand, controller 52 may disable delivery of ablation energy if the stored device usage information indicates that device 10 has been used on a previous patient.

To determine whether the device 10 has been previously used and to appropriately control delivery of ablation energy, controller 52 compares the stored device usage information with various parameters to determine whether a device 10 has been previously used to perform ablations on another patient. These parameters may include, for example, a maximum allowable elapsed time of use, a maximum allowable amount of time that ablation energy may be delivered by the device (a maximum allowable ablation time), a maximum number of times the device may deliver ablation energy to the target prostate tissue, and/or some other appropriate parameter which may indicate whether the device has been previously used on a different patient.

Controller 52 may compare the stored device usage information with these parameters to determine whether the device has been previously used. By querying single use lock-out 80 and receiving the stored device usage information, controller 10 can determine, for example, whether the maximum allowable elapsed time of use of device 10 has been exceeded, whether the maximum allowable ablation time has been exceeded and/or whether a maximum number of ablations have been previously performed using device 10. If one or more of these parameters indicates that the device has been used on a previous patient, controller 52 may control ablation energy delivery unit 53 such that no ablation current is applied to needles 30. This may help prevent inadvertent or intentional use of the device on more than one patient. In addition, controller 52 may cause a corresponding error message to be displayed on user interface 54 (see FIG. 1) to alert the physician that device 10 has been used before and should be discarded. Ablation energy generator 50 may also continuously query single-use lockout after power-on to minimize the risk that device 10 will be used to perform ablations on multiple patients without switching device 10 off between procedures.

The maximum allowable elapsed time of use, the maximum allowable ablation time and the maximum number of allowed ablations may be chosen to provide a reasonable amount of time and a reasonable number of ablations to complete an entire ablation procedure on a single patient but not so much time or so many ablations that the device 10 may be inadvertently used on more than one patient. The maximum allowable elapsed time of use and the maximum allowable ablation time may be based on, for example, the corresponding amounts of time in which the majority of ablation procedures should reasonably be completed. The maximum allowable elapsed time of use may be in the range of 2 to 5 hours, for example. Similarly, the maximum allowable time that ablation energy may be applied may in the range of 0.5 to 1.5 hours, for example. A specific embodiment may set the maximum allowable elapsed time of use at 4 hours and the maximum allowable ablation time at 75 minutes, for example. The maximum number of allowed ablations may be based on the number of ablations reasonably required in the majority of ablation procedures. The maximum number of allowed ablations may be in the range of 20-30 ablations, for example. A specific embodiment may set the maximum number of allowed ablations at 25 ablations, for example.

Single-use lockout 80 may also be used to store error information in the event that a malfunction occurs during an ablation procedure. If a malfunction occurs, controller 42 may write information concerning the error to either memory 86 or 88. The error information may include, for example, error codes indicative of the type of error that occurred and/or timing information concerning when the error took place. This error information may be later retrieved and analyzed by maintenance personnel when processing devices returned to the manufacturer to help identify the malfunction and why it occurred. FIG. 6A is a side view of needle deployment mechanism 100 at rest inside housing

12 of a device 10 such as that shown in FIG. 1. Needle deployment mechanism 100 includes four main elements: needle block 108, sheath block 110, spring 112 and 6mm catch 114. Needle block 108 actuates push rods 104 which deploy/retract needles 30. Similarly, sheath block 110 actuates push rods 102 which deploy/retract the needle sheaths. Sheath block 110 and needle block 108 are butted up next to each other, and are attached with snap fit 109. Spring 112 is attached to anchor block 111 and sheath block 110 and acts to pull sheath block 110 backward toward anchor block 111. 6mm catch 114 includes a stop 126 and an extension 124.

An endoscope may be placed in scope tube 106 to allow a physician to view the placement of the distal end of the catheter 14 within the urethra. In addition, needle block

108 and sheath block 110 are slidably connected to scope tube 106. Actuation of lever 18 causes needle block 108 and sheath block 110 to move forward in the direction indicated by arrow 120 along scope tube 106.

In operation, the physician squeezes lever 18 to actuate needle engagement mechanism 118 attached to needle block 108. This causes needle block 108 to begin its forward movement in the direction indicated by arrow 120 to advance needles 30 into the prostate tissue.

In FIG. 6B, because the needle block 108 and sheath block 110 are connected by snap fit 109, sheath block 110 moves forward along with needle block 108 in the directions indicated by arrows 130 and 132, respectively. As can be seen in FIG. 6B, sheath block 110 includes arms 115 that extend through needle block 108 and hold sheath block 110 and needle block 108 in place with respect to each other. At this point, needle block 108 and sheath block 110 move forward at the same rate.

In FIG. 6C, slide cap 122 of needle block 108 hits extension 124 of 6mm catch 114. This causes 6mm catch 114 to move up in the direction indicated by arrow 134, allowing sheath block 110 to move forward.

In FIG. 6D, needle block 108 and sheath block 110 are still moving forward together. As extension 124 moves past slide cap 122, 6mm catch moves down in the direction indicated by arrow 136. Spring 112 continues to pull backward on sheath block 110, although sheath block 110 continues to move forward along with needle block 108 because of the connection provided by snap fit 109. At this point, the sheath and the needle are both extended substantially the same depth from the needle exit port at the distal end of catheter 14.

FIG. 6E is a top view of needle deployment mechanism 100. Sheath block 110 includes sideways tabs 128A and 128B. As sheath block 110 continues to move forward along with needle block 108, tabs 128A and 128B attached to sheath block 110 hit tab releases 129A and 129B (129B not shown) located in the sides of housing 12. Tab releases 129 A and 129B push the tabs 128A and 128B back, causing movement of half arrows 13 IA and 13 IB in the direction indicated by arrows 138 and 139, respectively, releasing the snap fit 109. Once snap fit 109 is released, sheath block 110 is free of needle block 108 and the force applied by spring 112 pulls sheath block 110 backward. The spring pulls sheath block 110 back to stop 126 on 6mm catch 114. As this occurs, the needle continues moving forward, while the sheath stops moving forward and is retracted back to the 6mm position along with sheath block 110. 6 mm catch 114 may be adjusted to provide for a different sheath depth in embodiments where a sheath depth of other than 6 millimeters is used.

FIG. 6F is another side view of the needle deployment mechanism 100. In this view, sheath block 110 retracts back to 6mm position determined by stop 126 on the 6mm catch 114.

In FIG. 6G, needle block 108 continues to move forward while sheath block 110 stays in the same 6mm position. At this point, the needles are fully deployed to the desired needle depth and the device is prepared to perform an ablation. FIG. 6H is another side view of the needle deployment mechanism showing retraction of the needles. When an ablation is complete, the needles are retracted back into the catheter in preparation to reposition the device within or withdraw the device from the urethra. To retract the needles, the physician may move the lever 18 in the direction indicated by arrow 145. Alternatively, the physician may activate automatic retraction button 34 (see FIG. 1) to automatically retract the needles. As needle block 108 begins to move back, slide cap 122 hits protrusion 124 on 6mm catch 114, which moves the 6mm catch 114 upward in the direction indicated by arrow 144.

FIG. 61 shows that the sheath block 110 is now free of stop 126 and is pulled back by spring 112 to fully retract the sheaths. At the same time, needle block 108 continues to move backward as indicated by arrow 148 in FIG. 6 J until it is butted up against sheath block 110. At this point both the needles and the sheaths are fully retracted.

FIG. 7 shows a side view of automatic needle retraction mechanism 150. In this embodiment, the automatic needle retraction mechanism is located inside the handle 32 of a TUNA device 10. Automatic needle retraction mechanism 150 includes a retraction button 24, retraction spring 154, and lever arm 155.

A lever engagement tooth 164 is located at the top of lever arm 155. As the physician actuates lever 18 to deploy the needles, ratchets 162 on lever extension 160 hit up against tooth 164. As the lever 18 continues to move, the interaction between tooth 164 and ratchets 162 produce a ratcheting effect. At the start of an ablation procedure, the physician determines the appropriate needle depth and manually rotates needle depth selector 22 (see FIG.l) to the corresponding position. In FIG. 7, circular element 168 and needle depth key 170 are attached to and rotate along with the needle depth selector 22. Needle depth key 170 includes six faces, each face having a unique length as measured across the edge of the face. Each face also has a unique radius as measured from the edge of the face to center point 172 of the needle depth selector 22. As needle depth selector 22 is rotated, the face coming into contact with lever extension 160 changes based on the position of the dial. This causes lever engagement tooth 164 to engage the ratchet 162 corresponding to the needle depth as selected on the needle depth selector 22.

Once the needles have been deployed to the selected depth, tooth 164 holds lever 18 in place at the appropriate ratchet position 162 to maintain the selected needle depth. The needles and sheath are thus held in position by the interaction between tooth 164 and ratchets 162 while ablation energy is applied to the target prostate tissue.

When the needles are to be retracted, the physician may depress retraction button 24 to cause automatic retraction of the needles. Retraction button 24 is spring loaded with retraction spring 154. When retraction button 24 is depressed, spring 154 is compressed and ledge 166 presses up onto the base of lever arm 155. Ledge 166 pushes upwardly on lever arm 155 resulting in an upward movement of lever arm 155. During this upward movement, knobs 158 of lever arm 155 slide inside of track 156 located on the inside of housing 12. Upward movement of lever arm 155 results in upward movement of tooth 164, releasing ratchets 162. With no opposing force remaining to counteract it, the backward pulling force applied by spring 112 on the needle block 108 and sheath block 110 is then free to fully pull back and retract the needles and the sheaths as described above with respect to FIGS. 6H-6J.

Referring again to FIG. 1, in one embodiment, device 10 is a single-use, disposable device. The device may be constructed using mostly plastic parts, reducing the weight of and simplifying manufacture and assembly of the device. Although the invention has been described generally with respect to a one piece, disposable TUNA device, it shall be understood that many of the features described herein may also be used with other conventional TUNA devices. For example, the simplified needle deployment mechanism may also be used in a conventional, TUNA device, such as those device with a reusable handle and replaceable catheter cartridge. The flexible catheter tip 60 may also be used with other types of TUNA devices. The automatic retraction mechanism described herein may also be incorporated into other types of TUNA devices and is not limited to use with the one piece, disposable device described herein. The invention can provide a number of advantages. Because the device is designed for one-time use, sterilization is not required. This may minimize preparation time between procedures as well as result in higher patient throughput. In addition, the one-piece design of the device means that no pre-procedure assembly is required, further reducing preparation time. Furthermore, time spent maintaining the device may be reduced or eliminated as the device is used only once and then discarded. In addition, because the device may include a simplified design constructed of mostly plastic parts, the resulting TUNA device may be more reliable, easier to manufacture, lighter in weight and easier for the physician to operate and maneuver. These features may result in a transurethral ablation device that enables the physician for perform faster, more accurate, and more efficient TUNA procedures.

As another advantage, the flexible catheter tip may provide increased patient comfort during insertion of the catheter into the urethra. As another advantage, the single use lockout helps to ensure that the device is used on only a single patient. In this way, the patient receives the benefit of a dedicated TUNA device, increasing procedural safety.

As yet another advantage, the simplified needle deployment mechanism may result in a TUNA device that is more reliable, easier to manufacture, lighter and easier for the physician to maneuver. As yet another advantage, the automatic needle retraction mechanism helps ensure full retraction of the needles. The automatic needle retraction feature thus may increase the safety of the procedure by reducing the likelihood of inadvertent failure to fully retract the needles before the catheter is repositioned within or withdrawn from the urethra, thus reducing the likelihood of damage to the prostate or the urethra, and the associated increases in patient pain and recovery time.

Thus, the invention can reduce the complexity of the ablation procedure, while increasing efficiency, convenience and safety. The invention can also result in a procedure in which the risk of damage to the urethra, patient pain and recovery times are minimized, thus further promoting patient safety and procedural efficacy.

In the claims, means-plus-function clauses are intended to cover the structures described herein as performing the recited function and not only structural equivalents but also equivalent structures. Thus, although a nail and a screw may not be structural equivalents in that a nail employs a cylindrical surface to secure wooden parts together, whereas a screw employs a helical surface, in the environment of fastening wooden parts a nail and a screw are equivalent structures.

Many embodiments of the invention have been described. Various modifications may be made without departing from the scope of the present invention. The preceding specific embodiments are illustrative of the practice of the invention. It is to be understood, therefore, that other expedients known to those skilled in the art or disclosed herein may be employed without departing from the invention or the scope of the claims. For example, the present invention further includes within its scope methods of making and using systems for transurethral ablation, as described herein. These and other embodiments are within the scope of the following claims.

Claims

CLAIMS:
1. A transurethral ablation device, comprising: a transurethral catheter; a lockout to store device usage information; an ablation needle extendable from a distal end of the catheter to penetrate prostate tissue of a patient and to deliver ablation energy to the prostate tissue; wherein a controller controls delivery of the ablation energy based on the stored device usage information.
2. The device of claim 1, wherein delivery of ablation energy is enabled by the controller if the stored device usage information indicates that the device has not been previously used on a different patient.
3. The device of claim 1, wherein delivery of ablation energy is disabled by the controller if the stored device usage information indicates that the device has been used on a previous patient.
4. The device of claim 1, further including a user interface to display a message based on the stored device usage information.
5. The device of claim 4, wherein the displayed message communicates whether the device has been used on a previous patient based on the stored device usage information.
6. The device of claim 4, wherein the displayed message communicates whether delivery of ablation energy is enabled or disabled based on the stored device usage information.
7. The device of claim 1, wherein the lockout stores a total elapsed time of use.
8. The device of claim 7, wherein the device is disabled if the total elapsed time of use is greater than 5 hours.
9. The device of claim 1, wherein the lockout stores a total amount of time that ablation energy is delivered to the prostate tissue.
10. The device of claim 9, wherein the device is disabled if the stored total amount of time that ablation energy is delivered to the prostate tissue is greater than 1.5 hours.
11. The device of claim 1 , wherein the lockout counts a number of times ablation energy is delivered to the prostate tissue.
12. The device of claim 11, wherein the device is disabled if the counted number of times ablation energy is delivered is greater than 30.
13. The device of claim 1, further comprising an ablation energy generator, wherein the ablation energy generator obtains the stored device usage information at power-on to determine whether the device has been used on a previous patient.
14. The device of claim 11, wherein the transurethral catheter has a distal end including a flexible catheter tip.
15. A transurethral ablation system, comprising: a transurethral ablation device, the device comprising: a transurethral catheter; a single-use lock out to store device usage information; an ablation needle extendable from a distal end of the catheter to penetrate prostate tissue of a patient and to deliver ablation energy to the prostate tissue; and an ablation energy generator to deliver ablation energy to the prostate tissue via the ablation needle and to control delivery of the ablation energy based on the stored device usage information.
16. The system of claim 15, wherein ablation energy generator enables delivery of ablation energy when the stored device usage information indicates that the device has not been used on a previous patient.
17. The system of claim 15, wherein ablation energy generator disables delivery of ablation energy when the stored device usage information indicates that the device has been used on a previous patient.
18. The system of claim 15, further including a user interface to display a message based on the stored device usage information.
19. The system of claim 18, wherein the displayed message communicates whether the device has been used on a previous patient based on the stored device usage information.
20. The system of claim 18, wherein the displayed message communicates whether delivery of ablation energy is enabled or disabled based on the stored device usage information.
21. The system of claim 15 , wherein the lockout stores a total elapsed calendar time of use.
22. The system of claim 21, wherein the ablation energy generator enables application of ablation energy when the stored total elapsed calendar time of use is less than 5 hours.
23. The system of claim 15, wherein the lockout stores an amount of time ablation energy is delivered to the prostate tissue.
24. The system of claim 23, wherein the ablation energy generator enables application of ablation energy when the stored amount of time ablation energy is delivered to the prostate tissue is less than 1.5 hours.
25. The system of claim 5, wherein the lockout stores a number of times ablation energy is delivered to the prostate tissue.
26. The system of claim 25, wherein the ablation energy generator enables application of ablation energy when the counted number of times ablation energy is delivered is less than 30.
27. The system of claim 1, wherein the ablation energy generator obtains the stored device usage information at power-on to determine whether the device has been previously used on a different patient.
28. The system of claim 27, wherein the ablation energy generator continuously obtains the stored device usage information after power-on to determine whether the device has been previously used on a different patient.
29. A transurethral ablation system, comprising: means for storing device usage information; means for delivering ablation energy to prostate tissue of a patient; wherein delivery of the ablation energy is controlled based on the stored device usage information.
30. The system of claim 29, further comprising means for enabling delivery of ablation energy if the stored device usage information indicates that the device has not been previously used on a different patient.
31. The system of claim 30, wherein the means for enabling delivery of ablation energy is further for obtaining the stored device usage information.
32. The system of claim 30, wherein the means for enabling delivery of ablation energy is further for continuously obtaining the stored device usage information after power-on and enabling delivery of ablation energy based on the continuously obtained stored device usage information.
33. The system of claim 30, wherein the means for enabling delivery of ablation energy is further for disabling delivery of ablation energy if the stored device usage information indicates that the device has been previously used on a different patient.
34. The system of claim 29, further including means for displaying a message based on the stored device usage information.
35. A method comprising: monitoring device usage of a transurethral ablation device adapted to deliver ablation energy to prostate tissue of a patient; and enabling delivery of ablation energy based on the monitored device usage.
36. The method of claim 35, wherein monitoring device usage further includes monitoring a total time of use of the device.
37. The method of claim 36, wherein enabling delivery of ablation energy further includes enabling delivery of ablation energy when the monitored total time of use of the device is less than a maximum allowable total time of use.
38. The method of claim 36, further comprising disabling delivery of ablation energy when the monitored total time of use of the device is greater a maximum allowable total time of use.
39. The method of claim 38 wherein the maximum allowable time of use is between 3 and 5 hours.
40. The method of claim 35, wherein monitoring device usage further includes monitoring an amount of time that ablation energy is delivered by the device.
41. The method of claim 40, wherein enabling delivery of ablation energy further includes enabling delivery of ablation energy when the monitored amount of time that ablation energy is delivered by the device is less than a maximum allowable amount of time that ablation energy may be delivered by the device.
42. The method of claim 40, further comprising disabling delivery of ablation energy when the monitored amount of time that ablation energy is delivered by the device is greater a maximum allowable amount of time that power may be delivered by the device.
43. The method of claim 42 wherein the maximum allowable amount of time that ablation energy may be delivered by the device is between 1 and 1.5 hours.
44. The method of claim 35, wherein monitoring device usage further includes counting a number of times that ablation energy is delivered by the device.
45. The method of claim 44, wherein enabling delivery of ablation energy further includes enabling delivery of ablation energy when the counted number of times that ablation energy is delivered by the device is less than a maximum allowable number of times that ablation energy may be delivered by the device.
46. The method of claim 44, further comprising disabling delivery of ablation energy when the counted number of times that ablation energy is delivered by the device is greater than a maximum allowable number of times that ablation energy may be delivered by the device.
47. The method of claim 46 wherein the maximum number of times that ablation energy may be delivered by the device is between 20 and 30.
48. A transurethral ablation device, comprising: a transurethral catheter having a proximal end and a distal end; at least one ablation needle deployable from the distal end of the catheter to penetrate prostate tissue of a patient and to deliver ablation energy to the prostate tissue; and an automatic needle retraction mechanism to automatically fully retract the needles within the catheter.
49. The device of claim 1, wherein the automatic needle retraction mechanism further includes a physician actuatable retraction button.
50. The device of claim 2, wherein the automatic needle retraction mechanism fully retracts the needles within the catheter upon actuation of the retraction button.
51. The device of claim 1 , further comprising: a lever actuatable by a physician to deploy the needles from the distal end of the catheter; a plurality of ratchet positions associated with the lever, each ratchet position corresponding to a different one of a plurality of available needle depths; a needle depth selection mechanism to determine a selected needle depth from among the available needle depths; and a ratchet engagement tooth to engage the ratchet position corresponding to the selected needle depth as determined by the needle selection mechanism and to so maintain the desired needle depth.
52. The device of claim 4, wherein the automatic needle retraction mechanism further comprises: a retraction button; and a lever arm having a proximal end aligned to engage the retraction button and having the ratchet engagement tooth disposed at a distal end.
53. The device of claim 5, wherein actuation of the retraction button moves the lever arm to release the ratchet engagement tooth from the selected ratchet position.
54. The device of claim 6, further including a needle retraction spring configured to apply a retraction force to fully retract the needles upon release of the ratchet engagement tooth from the selected ratchet position.
55. The device of claim 5, wherein the retraction button is spring-loaded.
56. The device of claim 5, further comprising a housing having a track to slidably engage the lever arm upon actuation of the retraction button.
57. The device of claim 1, further comprising a keyed member having a plurality of keyed positions each corresponding to a different one of the plurality of available needle depths, and wherein the keyed member engages the lever with the keyed position corresponding to the selected needle depth such that the ratchet engagement tooth engages the ratchet position corresponding to the selected needle depth.
58. The device of claim 1, further including a lockout to store device usage information, and wherein delivery of the ablation energy is controlled based on the stored device usage information.
59. The device of claim 1, wherein the transurethral catheter has a distal end including a flexible catheter tip.
60. A transurethral ablation device, comprising: a transurethral catheter; at least one ablation needle extendable from the distal end of the catheter to penetrate prostate tissue of a patient and to deliver ablation energy to the prostate tissue, wherein an insulative sheath surrounds the needle; and a needle deployment mechanism to advance the needles out of the distal end of the catheter, the needle deployment mechanism comprising: a lever actuatable by a physician; a needle block to advance the needle to a desired needle depth in response to actuation of the lever; a sheath block to advance the sheath to a first predetermined sheath depth in response to actuation of the lever; a spring connected to retract the sheath block after advancement of the needle to a predetermined needle depth, such that the sheath is retracted to a second predetermined sheath depth; a catch positioned to maintain a fixed position of the sheath block such that the second predetermined sheath depth is maintained.
61. The device of claim 1, wherein the first predetermined sheath depth is between 8 and 10 millimeters.
62. The device of claim 1, wherein the second predetermined sheath depth is approximately 6 millimeters.
63. The device of claim 1, wherein the sheath protects the urethra during delivery of ablation energy to the prostate tissue.
64. The device of claim 1, further including a snap fit connecting the sheath block to the needle block.
65. The device of claim 1, further including at least one tab extending outwardly from a side of the needle block.
66. The device of claim 1, further including a lockout to store device usage information, and wherein delivery of the ablation energy is controlled based on the stored device usage information.
67. The device of claim 1, wherein the transurethral catheter has a distal end including a flexible catheter tip.
68. A transurethral ablation device, comprising: a transurethral catheter insertable into a urethra of a patient; a catheter tip, wherein the catheter tip comprises: a rigid core positioned at a distal end of the catheter; and a flexible tip positioned at a distal end of the rigid core; at least one ablation needle extendable from the rigid core of the catheter tip to penetrate prostate tissue of the patient and to deliver ablation energy to the prostate tissue.
69. The device of claim 1, wherein the rigid core comprises at least one needle exit port from which the ablation needle is extendable.
70. The device of claim 1, wherein the rigid core comprises a fluid delivery lumen connected to receive fluid from the transurethral catheter.
71. The device of claim 3, wherein the flexible tip includes a notch positioned to receive the fluid from the fluid delivery lumen and deliver the fluid to the urethra.
72. The device of claim 4 wherein the notch is positioned on a side of needle extension from the rigid core.
73. The device of claim 4, wherein the fluid cools the urethra.
74. The device of claim 1, further comprising at least one guide tube extending from a proximal end of the catheter to the exit port of the rigid core.
75. The device of claim 1, further comprising a thermocouple to monitor temperature inside the urethra.
76. The device of claim 8, wherein the thermocouple is attached to an outside wall of the guide tube proximate the exit port.
77. The device of claim 8, wherein the thermocouple monitors the temperature inside the urethra via thermal conduction.
78. The device of claim 1, wherein the rigid core has a Shore A hardness of at least 70.
79. The device of claim 1, wherein the rigid core is constructed of a thermoplastic elastomer.
80. The device of claim 1, wherein the flexible tip has a Shore A hardness of between 30 and 70.
81. The device of claim 10, wherein the flexible tip is constructed of a thermoplastic elastomer.
82. The device of claim 1, wherein the flexible tip is substantially elbow shaped.
83. The device of claim 1, further including support structures extending partially within the flexible tip.
84. The device of claim 1, further including a lockout to store device usage information, and wherein delivery of the ablation energy is controlled based on the stored device usage information.
PCT/US2005/036906 2004-10-13 2005-10-13 Single-use transurethral needle ablation device WO2006044581A3 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
US10/964,546 2004-10-13
US10/964,548 2004-10-13
US10964546 US20060079881A1 (en) 2004-10-13 2004-10-13 Single-use transurethral needle ablation
US10/964,551 2004-10-13
US10964548 US7261709B2 (en) 2004-10-13 2004-10-13 Transurethral needle ablation system with automatic needle retraction
US10/963,971 2004-10-13
US10963971 US7335197B2 (en) 2004-10-13 2004-10-13 Transurethral needle ablation system with flexible catheter tip
US10964551 US7261710B2 (en) 2004-10-13 2004-10-13 Transurethral needle ablation system

Publications (2)

Publication Number Publication Date
WO2006044581A2 true true WO2006044581A2 (en) 2006-04-27
WO2006044581A3 true WO2006044581A3 (en) 2006-08-03

Family

ID=35793797

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/036906 WO2006044581A3 (en) 2004-10-13 2005-10-13 Single-use transurethral needle ablation device

Country Status (1)

Country Link
WO (1) WO2006044581A3 (en)

Cited By (222)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1884205A2 (en) 2006-08-02 2008-02-06 Ethicon Endo-Surgery, Inc. Pneumatically powered surigcal cutting and fastening instrument with replaceable power sources
WO2008051734A2 (en) * 2006-10-23 2008-05-02 Boston Scientific Limited Device for circulating heated fluid
US7644848B2 (en) 2006-01-31 2010-01-12 Ethicon Endo-Surgery, Inc. Electronic lockouts and surgical instrument including same
US7658311B2 (en) 2007-06-22 2010-02-09 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with a geared return mechanism
US7665647B2 (en) 2006-09-29 2010-02-23 Ethicon Endo-Surgery, Inc. Surgical cutting and stapling device with closure apparatus for limiting maximum tissue compression force
US7669747B2 (en) 2007-06-29 2010-03-02 Ethicon Endo-Surgery, Inc. Washer for use with a surgical stapling instrument
US7670334B2 (en) 2006-01-10 2010-03-02 Ethicon Endo-Surgery, Inc. Surgical instrument having an articulating end effector
US7669746B2 (en) 2005-08-31 2010-03-02 Ethicon Endo-Surgery, Inc. Staple cartridges for forming staples having differing formed staple heights
US7673783B2 (en) 2005-11-04 2010-03-09 Ethicon Endo-Surgery, Inc. Surgical stapling instruments structured for delivery of medical agents
US7673780B2 (en) 2005-11-09 2010-03-09 Ethicon Endo-Surgery, Inc. Articulation joint with improved moment arm extension for articulating an end effector of a surgical instrument
US7673781B2 (en) 2005-08-31 2010-03-09 Ethicon Endo-Surgery, Inc. Surgical stapling device with staple driver that supports multiple wire diameter staples
EP2170459A1 (en) * 2007-07-12 2010-04-07 Asthmatx, Inc. Systems and methods for delivering energy to passageways in a patient
US7721931B2 (en) 2007-01-10 2010-05-25 Ethicon Endo-Surgery, Inc. Prevention of cartridge reuse in a surgical instrument
US7721936B2 (en) 2007-01-10 2010-05-25 Ethicon Endo-Surgery, Inc. Interlock and surgical instrument including same
US7721934B2 (en) 2006-01-31 2010-05-25 Ethicon Endo-Surgery, Inc. Articulatable drive shaft arrangements for surgical cutting and fastening instruments
US7731072B2 (en) 2007-06-18 2010-06-08 Ethicon Endo-Surgery, Inc. Surgical stapling and cutting instrument with improved anvil opening features
US7738971B2 (en) 2007-01-10 2010-06-15 Ethicon Endo-Surgery, Inc. Post-sterilization programming of surgical instruments
US7740159B2 (en) 2006-08-02 2010-06-22 Ethicon Endo-Surgery, Inc. Pneumatically powered surgical cutting and fastening instrument with a variable control of the actuating rate of firing with mechanical power assist
US7753245B2 (en) 2007-06-22 2010-07-13 Ethicon Endo-Surgery, Inc. Surgical stapling instruments
US7753904B2 (en) 2006-01-31 2010-07-13 Ethicon Endo-Surgery, Inc. Endoscopic surgical instrument with a handle that can articulate with respect to the shaft
US7766210B2 (en) 2006-01-31 2010-08-03 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting and fastening instrument with user feedback system
US7766209B2 (en) 2008-02-13 2010-08-03 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with improved firing trigger arrangement
US7770775B2 (en) 2006-01-31 2010-08-10 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting and fastening instrument with adaptive user feedback
US7793812B2 (en) 2008-02-14 2010-09-14 Ethicon Endo-Surgery, Inc. Disposable motor-driven loading unit for use with a surgical cutting and stapling apparatus
US7799039B2 (en) 2005-11-09 2010-09-21 Ethicon Endo-Surgery, Inc. Surgical instrument having a hydraulically actuated end effector
US7798386B2 (en) 2007-05-30 2010-09-21 Ethicon Endo-Surgery, Inc. Surgical instrument articulation joint cover
US7810693B2 (en) 2007-05-30 2010-10-12 Ethicon Endo-Surgery, Inc. Surgical stapling and cutting instrument with articulatable end effector
US7810692B2 (en) 2008-02-14 2010-10-12 Ethicon Endo-Surgery, Inc. Disposable loading unit with firing indicator
US7819298B2 (en) 2008-02-14 2010-10-26 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with control features operable with one hand
US7819299B2 (en) 2007-06-04 2010-10-26 Ethicon Endo-Surgery, Inc. Surgical instrument having a common trigger for actuating an end effector closing system and a staple firing system
US7819296B2 (en) 2008-02-14 2010-10-26 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with retractable firing systems
US7819297B2 (en) 2008-02-14 2010-10-26 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with reprocessible handle assembly
US7832408B2 (en) 2007-06-04 2010-11-16 Ethicon Endo-Surgery, Inc. Surgical instrument having a directional switching mechanism
US7832612B2 (en) 2008-09-19 2010-11-16 Ethicon Endo-Surgery, Inc. Lockout arrangement for a surgical stapler
US7837080B2 (en) 2008-09-18 2010-11-23 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with device for indicating when the instrument has cut through tissue
US7845537B2 (en) 2006-01-31 2010-12-07 Ethicon Endo-Surgery, Inc. Surgical instrument having recording capabilities
US7857185B2 (en) 2008-02-14 2010-12-28 Ethicon Endo-Surgery, Inc. Disposable loading unit for surgical stapling apparatus
US7861906B2 (en) 2008-02-14 2011-01-04 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with articulatable components
US7866527B2 (en) 2008-02-14 2011-01-11 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with interlockable firing system
US7900805B2 (en) 2007-01-10 2011-03-08 Ethicon Endo-Surgery, Inc. Surgical instrument with enhanced battery performance
US7905380B2 (en) 2007-06-04 2011-03-15 Ethicon Endo-Surgery, Inc. Surgical instrument having a multiple rate directional switching mechanism
US7913891B2 (en) 2008-02-14 2011-03-29 Ethicon Endo-Surgery, Inc. Disposable loading unit with user feedback features and surgical instrument for use therewith
US7918377B2 (en) 2008-10-16 2011-04-05 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with apparatus for providing anvil position feedback
US7922061B2 (en) 2008-05-21 2011-04-12 Ethicon Endo-Surgery, Inc. Surgical instrument with automatically reconfigurable articulating end effector
US7934630B2 (en) 2005-08-31 2011-05-03 Ethicon Endo-Surgery, Inc. Staple cartridges for forming staples having differing formed staple heights
US7954682B2 (en) 2007-01-10 2011-06-07 Ethicon Endo-Surgery, Inc. Surgical instrument with elements to communicate between control unit and end effector
US7959051B2 (en) 2008-02-15 2011-06-14 Ethicon Endo-Surgery, Inc. Closure systems for a surgical cutting and stapling instrument
US7980443B2 (en) 2008-02-15 2011-07-19 Ethicon Endo-Surgery, Inc. End effectors for a surgical cutting and stapling instrument
US8020743B2 (en) 2008-10-15 2011-09-20 Ethicon Endo-Surgery, Inc. Powered articulatable surgical cutting and fastening instrument with flexible drive member
US8056787B2 (en) 2007-03-28 2011-11-15 Ethicon Endo-Surgery, Inc. Surgical stapling and cutting instrument with travel-indicating retraction member
US8066167B2 (en) 2009-03-23 2011-11-29 Ethicon Endo-Surgery, Inc. Circular surgical stapling instrument with anvil locking system
USD650074S1 (en) 2010-10-01 2011-12-06 Ethicon Endo-Surgery, Inc. Surgical instrument
US8083120B2 (en) 2008-09-18 2011-12-27 Ethicon Endo-Surgery, Inc. End effector for use with a surgical cutting and stapling instrument
US8136712B2 (en) 2009-12-10 2012-03-20 Ethicon Endo-Surgery, Inc. Surgical stapler with discrete staple height adjustment and tactile feedback
US8141762B2 (en) 2009-10-09 2012-03-27 Ethicon Endo-Surgery, Inc. Surgical stapler comprising a staple pocket
US8157145B2 (en) 2007-05-31 2012-04-17 Ethicon Endo-Surgery, Inc. Pneumatically powered surgical cutting and fastening instrument with electrical feedback
US8161977B2 (en) 2006-01-31 2012-04-24 Ethicon Endo-Surgery, Inc. Accessing data stored in a memory of a surgical instrument
US8186555B2 (en) 2006-01-31 2012-05-29 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting and fastening instrument with mechanical closure system
US8210411B2 (en) 2008-09-23 2012-07-03 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting instrument
US8215531B2 (en) 2004-07-28 2012-07-10 Ethicon Endo-Surgery, Inc. Surgical stapling instrument having a medical substance dispenser
US8220688B2 (en) 2009-12-24 2012-07-17 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting instrument with electric actuator directional control assembly
US8236010B2 (en) 2006-03-23 2012-08-07 Ethicon Endo-Surgery, Inc. Surgical fastener and cutter with mimicking end effector
US8267300B2 (en) 2009-12-30 2012-09-18 Ethicon Endo-Surgery, Inc. Dampening device for endoscopic surgical stapler
US8308040B2 (en) 2007-06-22 2012-11-13 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with an articulatable end effector
US8322455B2 (en) 2006-06-27 2012-12-04 Ethicon Endo-Surgery, Inc. Manually driven surgical cutting and fastening instrument
US8353438B2 (en) 2009-11-19 2013-01-15 Ethicon Endo-Surgery, Inc. Circular stapler introducer with rigid cap assembly configured for easy removal
US8353439B2 (en) 2009-11-19 2013-01-15 Ethicon Endo-Surgery, Inc. Circular stapler introducer with radially-openable distal end portion
US8360296B2 (en) 2010-09-09 2013-01-29 Ethicon Endo-Surgery, Inc. Surgical stapling head assembly with firing lockout for a surgical stapler
US8371491B2 (en) 2008-02-15 2013-02-12 Ethicon Endo-Surgery, Inc. Surgical end effector having buttress retention features
US8393514B2 (en) 2010-09-30 2013-03-12 Ethicon Endo-Surgery, Inc. Selectively orientable implantable fastener cartridge
US8397971B2 (en) 2009-02-05 2013-03-19 Ethicon Endo-Surgery, Inc. Sterilizable surgical instrument
US8414577B2 (en) 2009-02-05 2013-04-09 Ethicon Endo-Surgery, Inc. Surgical instruments and components for use in sterile environments
US8444036B2 (en) 2009-02-06 2013-05-21 Ethicon Endo-Surgery, Inc. Motor driven surgical fastener device with mechanisms for adjusting a tissue gap within the end effector
US8453908B2 (en) 2008-02-13 2013-06-04 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with improved firing trigger arrangement
US8453907B2 (en) 2009-02-06 2013-06-04 Ethicon Endo-Surgery, Inc. Motor driven surgical fastener device with cutting member reversing mechanism
US8459525B2 (en) 2008-02-14 2013-06-11 Ethicon Endo-Sugery, Inc. Motorized surgical cutting and fastening instrument having a magnetic drive train torque limiting device
US8459520B2 (en) 2007-01-10 2013-06-11 Ethicon Endo-Surgery, Inc. Surgical instrument with wireless communication between control unit and remote sensor
US8479969B2 (en) 2007-01-10 2013-07-09 Ethicon Endo-Surgery, Inc. Drive interface for operably coupling a manipulatable surgical tool to a robot
US8485413B2 (en) 2009-02-05 2013-07-16 Ethicon Endo-Surgery, Inc. Surgical stapling instrument comprising an articulation joint
US8517239B2 (en) 2009-02-05 2013-08-27 Ethicon Endo-Surgery, Inc. Surgical stapling instrument comprising a magnetic element driver
US8534528B2 (en) 2007-06-04 2013-09-17 Ethicon Endo-Surgery, Inc. Surgical instrument having a multiple rate directional switching mechanism
US8540133B2 (en) 2008-09-19 2013-09-24 Ethicon Endo-Surgery, Inc. Staple cartridge
US8540131B2 (en) 2011-03-15 2013-09-24 Ethicon Endo-Surgery, Inc. Surgical staple cartridges with tissue tethers for manipulating divided tissue and methods of using same
US8540128B2 (en) 2007-01-11 2013-09-24 Ethicon Endo-Surgery, Inc. Surgical stapling device with a curved end effector
US8561870B2 (en) 2008-02-13 2013-10-22 Ethicon Endo-Surgery, Inc. Surgical stapling instrument
US8573461B2 (en) 2008-02-14 2013-11-05 Ethicon Endo-Surgery, Inc. Surgical stapling instruments with cam-driven staple deployment arrangements
US8573465B2 (en) 2008-02-14 2013-11-05 Ethicon Endo-Surgery, Inc. Robotically-controlled surgical end effector system with rotary actuated closure systems
US8584919B2 (en) 2008-02-14 2013-11-19 Ethicon Endo-Sugery, Inc. Surgical stapling apparatus with load-sensitive firing mechanism
US8602288B2 (en) 2008-09-23 2013-12-10 Ethicon Endo-Surgery. Inc. Robotically-controlled motorized surgical end effector system with rotary actuated closure systems having variable actuation speeds
US8608046B2 (en) 2010-01-07 2013-12-17 Ethicon Endo-Surgery, Inc. Test device for a surgical tool
US8608044B2 (en) 2008-02-15 2013-12-17 Ethicon Endo-Surgery, Inc. Feedback and lockout mechanism for surgical instrument
US8608045B2 (en) 2008-10-10 2013-12-17 Ethicon Endo-Sugery, Inc. Powered surgical cutting and stapling apparatus with manually retractable firing system
US8616431B2 (en) 2007-06-04 2013-12-31 Ethicon Endo-Surgery, Inc. Shiftable drive interface for robotically-controlled surgical tool
US8622274B2 (en) 2008-02-14 2014-01-07 Ethicon Endo-Surgery, Inc. Motorized cutting and fastening instrument having control circuit for optimizing battery usage
US8622275B2 (en) 2009-11-19 2014-01-07 Ethicon Endo-Surgery, Inc. Circular stapler introducer with rigid distal end portion
US8632462B2 (en) 2011-03-14 2014-01-21 Ethicon Endo-Surgery, Inc. Trans-rectum universal ports
US8632535B2 (en) 2007-01-10 2014-01-21 Ethicon Endo-Surgery, Inc. Interlock and surgical instrument including same
US8632525B2 (en) 2010-09-17 2014-01-21 Ethicon Endo-Surgery, Inc. Power control arrangements for surgical instruments and batteries
US8636736B2 (en) 2008-02-14 2014-01-28 Ethicon Endo-Surgery, Inc. Motorized surgical cutting and fastening instrument
US8657176B2 (en) 2010-09-30 2014-02-25 Ethicon Endo-Surgery, Inc. Tissue thickness compensator for a surgical stapler
US8657174B2 (en) 2008-02-14 2014-02-25 Ethicon Endo-Surgery, Inc. Motorized surgical cutting and fastening instrument having handle based power source
US8672207B2 (en) 2010-07-30 2014-03-18 Ethicon Endo-Surgery, Inc. Transwall visualization arrangements and methods for surgical circular staplers
US8695866B2 (en) 2010-10-01 2014-04-15 Ethicon Endo-Surgery, Inc. Surgical instrument having a power control circuit
US8708213B2 (en) 2006-01-31 2014-04-29 Ethicon Endo-Surgery, Inc. Surgical instrument having a feedback system
US8721630B2 (en) 2006-03-23 2014-05-13 Ethicon Endo-Surgery, Inc. Methods and devices for controlling articulation
US8733613B2 (en) 2010-09-29 2014-05-27 Ethicon Endo-Surgery, Inc. Staple cartridge
US8747238B2 (en) 2012-06-28 2014-06-10 Ethicon Endo-Surgery, Inc. Rotary drive shaft assemblies for surgical instruments with articulatable end effectors
US8758391B2 (en) 2008-02-14 2014-06-24 Ethicon Endo-Surgery, Inc. Interchangeable tools for surgical instruments
US8763879B2 (en) 2006-01-31 2014-07-01 Ethicon Endo-Surgery, Inc. Accessing data stored in a memory of surgical instrument
US8783541B2 (en) 2003-05-20 2014-07-22 Frederick E. Shelton, IV Robotically-controlled surgical end effector system
US8783543B2 (en) 2010-07-30 2014-07-22 Ethicon Endo-Surgery, Inc. Tissue acquisition arrangements and methods for surgical stapling devices
US8789741B2 (en) 2010-09-24 2014-07-29 Ethicon Endo-Surgery, Inc. Surgical instrument with trigger assembly for generating multiple actuation motions
US8789739B2 (en) 2011-09-06 2014-07-29 Ethicon Endo-Surgery, Inc. Continuous stapling instrument
US8789740B2 (en) 2010-07-30 2014-07-29 Ethicon Endo-Surgery, Inc. Linear cutting and stapling device with selectively disengageable cutting member
US8800838B2 (en) 2005-08-31 2014-08-12 Ethicon Endo-Surgery, Inc. Robotically-controlled cable-based surgical end effectors
US8800841B2 (en) 2011-03-15 2014-08-12 Ethicon Endo-Surgery, Inc. Surgical staple cartridges
US8820603B2 (en) 2006-01-31 2014-09-02 Ethicon Endo-Surgery, Inc. Accessing data stored in a memory of a surgical instrument
US8844789B2 (en) 2006-01-31 2014-09-30 Ethicon Endo-Surgery, Inc. Automated end effector component reloading system for use with a robotic system
US8851354B2 (en) 2009-12-24 2014-10-07 Ethicon Endo-Surgery, Inc. Surgical cutting instrument that analyzes tissue thickness
US8858571B2 (en) 2005-11-09 2014-10-14 Ethicon Endo-Surgery, Inc. Hydraulically and electrically actuated articulation joints for surgical instruments
US8857693B2 (en) 2011-03-15 2014-10-14 Ethicon Endo-Surgery, Inc. Surgical instruments with lockable articulating end effector
US8875972B2 (en) 2008-02-15 2014-11-04 Ethicon Endo-Surgery, Inc. End effector coupling arrangements for a surgical cutting and stapling instrument
US8893949B2 (en) 2010-09-30 2014-11-25 Ethicon Endo-Surgery, Inc. Surgical stapler with floating anvil
US8893946B2 (en) 2007-03-28 2014-11-25 Ethicon Endo-Surgery, Inc. Laparoscopic tissue thickness and clamp load measuring devices
US8899466B2 (en) 2009-11-19 2014-12-02 Ethicon Endo-Surgery, Inc. Devices and methods for introducing a surgical circular stapling instrument into a patient
US8926598B2 (en) 2011-03-15 2015-01-06 Ethicon Endo-Surgery, Inc. Surgical instruments with articulatable and rotatable end effector
US8992422B2 (en) 2006-03-23 2015-03-31 Ethicon Endo-Surgery, Inc. Robotically-controlled endoscopic accessory channel
US9005230B2 (en) 2008-09-23 2015-04-14 Ethicon Endo-Surgery, Inc. Motorized surgical instrument
US9028494B2 (en) 2012-06-28 2015-05-12 Ethicon Endo-Surgery, Inc. Interchangeable end effector coupling arrangement
US9028519B2 (en) 2008-09-23 2015-05-12 Ethicon Endo-Surgery, Inc. Motorized surgical instrument
US9044229B2 (en) 2011-03-15 2015-06-02 Ethicon Endo-Surgery, Inc. Surgical fastener instruments
US9044230B2 (en) 2012-02-13 2015-06-02 Ethicon Endo-Surgery, Inc. Surgical cutting and fastening instrument with apparatus for determining cartridge and firing motion status
US9050084B2 (en) 2011-09-23 2015-06-09 Ethicon Endo-Surgery, Inc. Staple cartridge including collapsible deck arrangement
US9055941B2 (en) 2011-09-23 2015-06-16 Ethicon Endo-Surgery, Inc. Staple cartridge including collapsible deck
US9072536B2 (en) 2012-06-28 2015-07-07 Ethicon Endo-Surgery, Inc. Differential locking arrangements for rotary powered surgical instruments
US9072535B2 (en) 2011-05-27 2015-07-07 Ethicon Endo-Surgery, Inc. Surgical stapling instruments with rotatable staple deployment arrangements
US9078653B2 (en) 2012-03-26 2015-07-14 Ethicon Endo-Surgery, Inc. Surgical stapling device with lockout system for preventing actuation in the absence of an installed staple cartridge
US9101358B2 (en) 2012-06-15 2015-08-11 Ethicon Endo-Surgery, Inc. Articulatable surgical instrument comprising a firing drive
US9101385B2 (en) 2012-06-28 2015-08-11 Ethicon Endo-Surgery, Inc. Electrode connections for rotary driven surgical tools
US9119657B2 (en) 2012-06-28 2015-09-01 Ethicon Endo-Surgery, Inc. Rotary actuatable closure arrangement for surgical end effector
US9125662B2 (en) 2012-06-28 2015-09-08 Ethicon Endo-Surgery, Inc. Multi-axis articulating and rotating surgical tools
US9198662B2 (en) 2012-03-28 2015-12-01 Ethicon Endo-Surgery, Inc. Tissue thickness compensator having improved visibility
US9204880B2 (en) 2012-03-28 2015-12-08 Ethicon Endo-Surgery, Inc. Tissue thickness compensator comprising capsules defining a low pressure environment
US9204879B2 (en) 2012-06-28 2015-12-08 Ethicon Endo-Surgery, Inc. Flexible drive member
US9211120B2 (en) 2011-04-29 2015-12-15 Ethicon Endo-Surgery, Inc. Tissue thickness compensator comprising a plurality of medicaments
US9220500B2 (en) 2010-09-30 2015-12-29 Ethicon Endo-Surgery, Inc. Tissue thickness compensator comprising structure to produce a resilient load
US9220501B2 (en) 2010-09-30 2015-12-29 Ethicon Endo-Surgery, Inc. Tissue thickness compensators
US9226751B2 (en) 2012-06-28 2016-01-05 Ethicon Endo-Surgery, Inc. Surgical instrument system including replaceable end effectors
US9232941B2 (en) 2010-09-30 2016-01-12 Ethicon Endo-Surgery, Inc. Tissue thickness compensator comprising a reservoir
US9237891B2 (en) 2005-08-31 2016-01-19 Ethicon Endo-Surgery, Inc. Robotically-controlled surgical stapling devices that produce formed staples having different lengths
US9272406B2 (en) 2010-09-30 2016-03-01 Ethicon Endo-Surgery, Llc Fastener cartridge comprising a cutting member for releasing a tissue thickness compensator
US9283054B2 (en) 2013-08-23 2016-03-15 Ethicon Endo-Surgery, Llc Interactive displays
US9282974B2 (en) 2012-06-28 2016-03-15 Ethicon Endo-Surgery, Llc Empty clip cartridge lockout
US9289212B2 (en) 2010-09-17 2016-03-22 Ethicon Endo-Surgery, Inc. Surgical instruments and batteries for surgical instruments
US9289256B2 (en) 2012-06-28 2016-03-22 Ethicon Endo-Surgery, Llc Surgical end effectors having angled tissue-contacting surfaces
US9301752B2 (en) 2010-09-30 2016-04-05 Ethicon Endo-Surgery, Llc Tissue thickness compensator comprising a plurality of capsules
US9307989B2 (en) 2012-03-28 2016-04-12 Ethicon Endo-Surgery, Llc Tissue stapler having a thickness compensator incorportating a hydrophobic agent
US9307986B2 (en) 2013-03-01 2016-04-12 Ethicon Endo-Surgery, Llc Surgical instrument soft stop
US9314246B2 (en) 2010-09-30 2016-04-19 Ethicon Endo-Surgery, Llc Tissue stapler having a thickness compensator incorporating an anti-inflammatory agent
US9320523B2 (en) 2012-03-28 2016-04-26 Ethicon Endo-Surgery, Llc Tissue thickness compensator comprising tissue ingrowth features
US9332984B2 (en) 2013-03-27 2016-05-10 Ethicon Endo-Surgery, Llc Fastener cartridge assemblies
US9332987B2 (en) 2013-03-14 2016-05-10 Ethicon Endo-Surgery, Llc Control arrangements for a drive member of a surgical instrument
US9332974B2 (en) 2010-09-30 2016-05-10 Ethicon Endo-Surgery, Llc Layered tissue thickness compensator
US9345481B2 (en) 2013-03-13 2016-05-24 Ethicon Endo-Surgery, Llc Staple cartridge tissue thickness sensor system
US9351727B2 (en) 2013-03-14 2016-05-31 Ethicon Endo-Surgery, Llc Drive train control arrangements for modular surgical instruments
US9351726B2 (en) 2013-03-14 2016-05-31 Ethicon Endo-Surgery, Llc Articulation control system for articulatable surgical instruments
US9358005B2 (en) 2010-09-30 2016-06-07 Ethicon Endo-Surgery, Llc End effector layer including holding features
US9364233B2 (en) 2010-09-30 2016-06-14 Ethicon Endo-Surgery, Llc Tissue thickness compensators for circular surgical staplers
US9364230B2 (en) 2012-06-28 2016-06-14 Ethicon Endo-Surgery, Llc Surgical stapling instruments with rotary joint assemblies
US9386984B2 (en) 2013-02-08 2016-07-12 Ethicon Endo-Surgery, Llc Staple cartridge comprising a releasable cover
US9386985B2 (en) 2012-10-15 2016-07-12 Ethicon Endo-Surgery, Llc Surgical cutting instrument
US9408606B2 (en) 2012-06-28 2016-08-09 Ethicon Endo-Surgery, Llc Robotically powered surgical device with manually-actuatable reversing system
US9549735B2 (en) 2013-12-23 2017-01-24 Ethicon Endo-Surgery, Llc Fastener cartridge comprising a firing member including fastener transfer surfaces
US9561038B2 (en) 2012-06-28 2017-02-07 Ethicon Endo-Surgery, Llc Interchangeable clip applier
US9572577B2 (en) 2013-03-27 2017-02-21 Ethicon Endo-Surgery, Llc Fastener cartridge comprising a tissue thickness compensator including openings therein
US9574644B2 (en) 2013-05-30 2017-02-21 Ethicon Endo-Surgery, Llc Power module for use with a surgical instrument
US9585657B2 (en) 2008-02-15 2017-03-07 Ethicon Endo-Surgery, Llc Actuator for releasing a layer of material from a surgical end effector
US9592053B2 (en) 2010-09-30 2017-03-14 Ethicon Endo-Surgery, Llc Staple cartridge comprising multiple regions
US9592086B2 (en) 2012-07-24 2017-03-14 Boston Scientific Scimed, Inc. Electrodes for tissue treatment
US9615826B2 (en) 2010-09-30 2017-04-11 Ethicon Endo-Surgery, Llc Multiple thickness implantable layers for surgical stapling devices
US9629814B2 (en) 2010-09-30 2017-04-25 Ethicon Endo-Surgery, Llc Tissue thickness compensator configured to redistribute compressive forces
US9629629B2 (en) 2013-03-14 2017-04-25 Ethicon Endo-Surgey, LLC Control systems for surgical instruments
US9642620B2 (en) 2013-12-23 2017-05-09 Ethicon Endo-Surgery, Llc Surgical cutting and stapling instruments with articulatable end effectors
US9649110B2 (en) 2013-04-16 2017-05-16 Ethicon Llc Surgical instrument comprising a closing drive and a firing drive operated from the same rotatable output
US9681870B2 (en) 2013-12-23 2017-06-20 Ethicon Llc Articulatable surgical instruments with separate and distinct closing and firing systems
US9690362B2 (en) 2014-03-26 2017-06-27 Ethicon Llc Surgical instrument control circuit having a safety processor
US9687230B2 (en) 2013-03-14 2017-06-27 Ethicon Llc Articulatable surgical instrument comprising a firing drive
US9693777B2 (en) 2014-02-24 2017-07-04 Ethicon Llc Implantable layers comprising a pressed region
US9724092B2 (en) 2013-12-23 2017-08-08 Ethicon Llc Modular surgical instruments
US9724094B2 (en) 2014-09-05 2017-08-08 Ethicon Llc Adjunct with integrated sensors to quantify tissue compression
US9724098B2 (en) 2012-03-28 2017-08-08 Ethicon Endo-Surgery, Llc Staple cartridge comprising an implantable layer
US9730695B2 (en) 2014-03-26 2017-08-15 Ethicon Endo-Surgery, Llc Power management through segmented circuit
US9737301B2 (en) 2014-09-05 2017-08-22 Ethicon Llc Monitoring device degradation based on component evaluation
US9743929B2 (en) 2014-03-26 2017-08-29 Ethicon Llc Modular powered surgical instrument with detachable shaft assemblies
US9757128B2 (en) 2014-09-05 2017-09-12 Ethicon Llc Multiple sensors with one sensor affecting a second sensor's output or interpretation
US9770245B2 (en) 2008-02-15 2017-09-26 Ethicon Llc Layer arrangements for surgical staple cartridges
US9788836B2 (en) 2014-09-05 2017-10-17 Ethicon Llc Multiple motor control for powered medical device
US9795382B2 (en) 2005-08-31 2017-10-24 Ethicon Llc Fastener cartridge assembly comprising a cam and driver arrangement
US9795384B2 (en) 2013-03-27 2017-10-24 Ethicon Llc Fastener cartridge comprising a tissue thickness compensator and a gap setting element
US9801628B2 (en) 2014-09-26 2017-10-31 Ethicon Llc Surgical staple and driver arrangements for staple cartridges
US9801626B2 (en) 2013-04-16 2017-10-31 Ethicon Llc Modular motor driven surgical instruments with alignment features for aligning rotary drive shafts with surgical end effector shafts
US9801627B2 (en) 2014-09-26 2017-10-31 Ethicon Llc Fastener cartridge for creating a flexible staple line
US9808246B2 (en) 2015-03-06 2017-11-07 Ethicon Endo-Surgery, Llc Method of operating a powered surgical instrument
US9808244B2 (en) 2013-03-14 2017-11-07 Ethicon Llc Sensor arrangements for absolute positioning system for surgical instruments
US9814462B2 (en) 2010-09-30 2017-11-14 Ethicon Llc Assembly for fastening tissue comprising a compressible layer
US9814618B2 (en) 2013-06-06 2017-11-14 Boston Scientific Scimed, Inc. Devices for delivering energy and related methods of use
US9820738B2 (en) 2014-03-26 2017-11-21 Ethicon Llc Surgical instrument comprising interactive systems
US9826978B2 (en) 2010-09-30 2017-11-28 Ethicon Llc End effectors with same side closure and firing motions
US9833241B2 (en) 2014-04-16 2017-12-05 Ethicon Llc Surgical fastener cartridges with driver stabilizing arrangements
US9839428B2 (en) 2013-12-23 2017-12-12 Ethicon Llc Surgical cutting and stapling instruments with independent jaw control features
US9844374B2 (en) 2014-12-18 2017-12-19 Ethicon Llc Surgical instrument systems comprising an articulatable end effector and means for adjusting the firing stroke of a firing member
US9844368B2 (en) 2013-04-16 2017-12-19 Ethicon Llc Surgical system comprising first and second drive systems
US9844375B2 (en) 2014-12-18 2017-12-19 Ethicon Llc Drive arrangements for articulatable surgical instruments
US9844376B2 (en) 2014-11-06 2017-12-19 Ethicon Llc Staple cartridge comprising a releasable adjunct material
US9861359B2 (en) 2006-01-31 2018-01-09 Ethicon Llc Powered surgical instruments with firing system lockout arrangements
US9888919B2 (en) 2013-03-14 2018-02-13 Ethicon Llc Method and system for operating a surgical instrument
US9895148B2 (en) 2015-03-06 2018-02-20 Ethicon Endo-Surgery, Llc Monitoring speed control and precision incrementing of motor for powered surgical instruments
US9901342B2 (en) 2015-03-06 2018-02-27 Ethicon Endo-Surgery, Llc Signal and power communication system positioned on a rotatable shaft
US9913642B2 (en) 2014-03-26 2018-03-13 Ethicon Llc Surgical instrument comprising a sensor system
US9924961B2 (en) 2015-03-06 2018-03-27 Ethicon Endo-Surgery, Llc Interactive feedback system for powered surgical instruments
US9924944B2 (en) 2014-10-16 2018-03-27 Ethicon Llc Staple cartridge comprising an adjunct material
US9931118B2 (en) 2015-02-27 2018-04-03 Ethicon Endo-Surgery, Llc Reinforced battery for a surgical instrument

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8905977B2 (en) 2004-07-28 2014-12-09 Ethicon Endo-Surgery, Inc. Surgical stapling instrument having an electroactive polymer actuated medical substance dispenser

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3144020A (en) * 1960-08-09 1964-08-11 Frank G Zingale Resectoscope sheath
WO1993025136A2 (en) * 1992-06-05 1993-12-23 Chin Albert K Method and apparatus for prostatic treatment
US5807309A (en) * 1992-08-12 1998-09-15 Vidamed, Inc. Transurethral needle ablation device and method for the treatment of the prostate
US5964756A (en) * 1997-04-11 1999-10-12 Vidamed, Inc. Transurethral needle ablation device with replaceable stylet cartridge
EP1201196A1 (en) * 2000-10-20 2002-05-02 Ethicon Endo-Surgery, Inc. Apparatus and method for altering generator functions in an ultrasonic surgical system
US6419690B1 (en) * 1997-03-13 2002-07-16 Endocare, Inc. Urethral warming catheter
US6611793B1 (en) * 1999-09-07 2003-08-26 Scimed Life Systems, Inc. Systems and methods to identify and disable re-use single use devices based on detecting environmental changes

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3144020A (en) * 1960-08-09 1964-08-11 Frank G Zingale Resectoscope sheath
WO1993025136A2 (en) * 1992-06-05 1993-12-23 Chin Albert K Method and apparatus for prostatic treatment
US5807309A (en) * 1992-08-12 1998-09-15 Vidamed, Inc. Transurethral needle ablation device and method for the treatment of the prostate
US6419690B1 (en) * 1997-03-13 2002-07-16 Endocare, Inc. Urethral warming catheter
US5964756A (en) * 1997-04-11 1999-10-12 Vidamed, Inc. Transurethral needle ablation device with replaceable stylet cartridge
US6611793B1 (en) * 1999-09-07 2003-08-26 Scimed Life Systems, Inc. Systems and methods to identify and disable re-use single use devices based on detecting environmental changes
EP1201196A1 (en) * 2000-10-20 2002-05-02 Ethicon Endo-Surgery, Inc. Apparatus and method for altering generator functions in an ultrasonic surgical system

Cited By (499)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8783541B2 (en) 2003-05-20 2014-07-22 Frederick E. Shelton, IV Robotically-controlled surgical end effector system
US9060770B2 (en) 2003-05-20 2015-06-23 Ethicon Endo-Surgery, Inc. Robotically-driven surgical instrument with E-beam driver
US8517244B2 (en) 2004-07-28 2013-08-27 Ethicon Endo-Surgery, Inc. Surgical stapling instrument having a medical substance dispenser
US9603991B2 (en) 2004-07-28 2017-03-28 Ethicon Endo-Surgery, Llc Surgical stapling instrument having a medical substance dispenser
US8215531B2 (en) 2004-07-28 2012-07-10 Ethicon Endo-Surgery, Inc. Surgical stapling instrument having a medical substance dispenser
US9737302B2 (en) 2004-07-28 2017-08-22 Ethicon Llc Surgical stapling instrument having a restraining member
US9585663B2 (en) 2004-07-28 2017-03-07 Ethicon Endo-Surgery, Llc Surgical stapling instrument configured to apply a compressive pressure to tissue
US9282966B2 (en) 2004-07-28 2016-03-15 Ethicon Endo-Surgery, Inc. Surgical stapling instrument
US9510830B2 (en) 2004-07-28 2016-12-06 Ethicon Endo-Surgery, Llc Staple cartridge
US9737303B2 (en) 2004-07-28 2017-08-22 Ethicon Llc Articulating surgical stapling instrument incorporating a two-piece E-beam firing mechanism
US9844379B2 (en) 2004-07-28 2017-12-19 Ethicon Llc Surgical stapling instrument having a clearanced opening
US9592052B2 (en) 2005-08-31 2017-03-14 Ethicon Endo-Surgery, Llc Stapling assembly for forming different formed staple heights
US9848873B2 (en) 2005-08-31 2017-12-26 Ethicon Llc Fastener cartridge assembly comprising a driver and staple cavity arrangement
US7669746B2 (en) 2005-08-31 2010-03-02 Ethicon Endo-Surgery, Inc. Staple cartridges for forming staples having differing formed staple heights
US9844373B2 (en) 2005-08-31 2017-12-19 Ethicon Llc Fastener cartridge assembly comprising a driver row arrangement
US9561032B2 (en) 2005-08-31 2017-02-07 Ethicon Endo-Surgery, Llc Staple cartridge comprising a staple driver arrangement
US8567656B2 (en) 2005-08-31 2013-10-29 Ethicon Endo-Surgery, Inc. Staple cartridges for forming staples having differing formed staple heights
US7934630B2 (en) 2005-08-31 2011-05-03 Ethicon Endo-Surgery, Inc. Staple cartridges for forming staples having differing formed staple heights
US9237891B2 (en) 2005-08-31 2016-01-19 Ethicon Endo-Surgery, Inc. Robotically-controlled surgical stapling devices that produce formed staples having different lengths
US9326768B2 (en) 2005-08-31 2016-05-03 Ethicon Endo-Surgery, Llc Staple cartridges for forming staples having differing formed staple heights
US8800838B2 (en) 2005-08-31 2014-08-12 Ethicon Endo-Surgery, Inc. Robotically-controlled cable-based surgical end effectors
US9839427B2 (en) 2005-08-31 2017-12-12 Ethicon Llc Fastener cartridge assembly comprising a fixed anvil and a staple driver arrangement
US8464923B2 (en) 2005-08-31 2013-06-18 Ethicon Endo-Surgery, Inc. Surgical stapling devices for forming staples with different formed heights
US9795382B2 (en) 2005-08-31 2017-10-24 Ethicon Llc Fastener cartridge assembly comprising a cam and driver arrangement
US9307988B2 (en) 2005-08-31 2016-04-12 Ethicon Endo-Surgery, Llc Staple cartridges for forming staples having differing formed staple heights
US8636187B2 (en) 2005-08-31 2014-01-28 Ethicon Endo-Surgery, Inc. Surgical stapling systems that produce formed staples having different lengths
US8317070B2 (en) 2005-08-31 2012-11-27 Ethicon Endo-Surgery, Inc. Surgical stapling devices that produce formed staples having different lengths
US7673781B2 (en) 2005-08-31 2010-03-09 Ethicon Endo-Surgery, Inc. Surgical stapling device with staple driver that supports multiple wire diameter staples
US7673783B2 (en) 2005-11-04 2010-03-09 Ethicon Endo-Surgery, Inc. Surgical stapling instruments structured for delivery of medical agents
US7673780B2 (en) 2005-11-09 2010-03-09 Ethicon Endo-Surgery, Inc. Articulation joint with improved moment arm extension for articulating an end effector of a surgical instrument
US9895147B2 (en) 2005-11-09 2018-02-20 Ethicon Llc End effectors for surgical staplers
US7799039B2 (en) 2005-11-09 2010-09-21 Ethicon Endo-Surgery, Inc. Surgical instrument having a hydraulically actuated end effector
US8858571B2 (en) 2005-11-09 2014-10-14 Ethicon Endo-Surgery, Inc. Hydraulically and electrically actuated articulation joints for surgical instruments
US7670334B2 (en) 2006-01-10 2010-03-02 Ethicon Endo-Surgery, Inc. Surgical instrument having an articulating end effector
US7770775B2 (en) 2006-01-31 2010-08-10 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting and fastening instrument with adaptive user feedback
US8820605B2 (en) 2006-01-31 2014-09-02 Ethicon Endo-Surgery, Inc. Robotically-controlled surgical instruments
US7721934B2 (en) 2006-01-31 2010-05-25 Ethicon Endo-Surgery, Inc. Articulatable drive shaft arrangements for surgical cutting and fastening instruments
US8763879B2 (en) 2006-01-31 2014-07-01 Ethicon Endo-Surgery, Inc. Accessing data stored in a memory of surgical instrument
US7753904B2 (en) 2006-01-31 2010-07-13 Ethicon Endo-Surgery, Inc. Endoscopic surgical instrument with a handle that can articulate with respect to the shaft
US8746529B2 (en) 2006-01-31 2014-06-10 Ethicon Endo-Surgery, Inc. Accessing data stored in a memory of a surgical instrument
US9743928B2 (en) 2006-01-31 2017-08-29 Ethicon Endo-Surgery, Inc. Surgical instrument having a feedback system
US8820603B2 (en) 2006-01-31 2014-09-02 Ethicon Endo-Surgery, Inc. Accessing data stored in a memory of a surgical instrument
US7845537B2 (en) 2006-01-31 2010-12-07 Ethicon Endo-Surgery, Inc. Surgical instrument having recording capabilities
US9326770B2 (en) 2006-01-31 2016-05-03 Ethicon Endo-Surgery, Llc Surgical instrument
US9113874B2 (en) 2006-01-31 2015-08-25 Ethicon Endo-Surgery, Inc. Surgical instrument system
US7766210B2 (en) 2006-01-31 2010-08-03 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting and fastening instrument with user feedback system
US9861359B2 (en) 2006-01-31 2018-01-09 Ethicon Llc Powered surgical instruments with firing system lockout arrangements
US8186555B2 (en) 2006-01-31 2012-05-29 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting and fastening instrument with mechanical closure system
US9517068B2 (en) 2006-01-31 2016-12-13 Ethicon Endo-Surgery, Llc Surgical instrument with automatically-returned firing member
US8752747B2 (en) 2006-01-31 2014-06-17 Ethicon Endo-Surgery, Inc. Surgical instrument having recording capabilities
US9289225B2 (en) 2006-01-31 2016-03-22 Ethicon Endo-Surgery, Llc Endoscopic surgical instrument with a handle that can articulate with respect to the shaft
US9451958B2 (en) 2006-01-31 2016-09-27 Ethicon Endo-Surgery, Llc Surgical instrument with firing actuator lockout
US8172124B2 (en) 2006-01-31 2012-05-08 Ethicon Endo-Surgery, Inc. Surgical instrument having recording capabilities
US8844789B2 (en) 2006-01-31 2014-09-30 Ethicon Endo-Surgery, Inc. Automated end effector component reloading system for use with a robotic system
US9439649B2 (en) 2006-01-31 2016-09-13 Ethicon Endo-Surgery, Llc Surgical instrument having force feedback capabilities
US7644848B2 (en) 2006-01-31 2010-01-12 Ethicon Endo-Surgery, Inc. Electronic lockouts and surgical instrument including same
US8161977B2 (en) 2006-01-31 2012-04-24 Ethicon Endo-Surgery, Inc. Accessing data stored in a memory of a surgical instrument
US8157153B2 (en) 2006-01-31 2012-04-17 Ethicon Endo-Surgery, Inc. Surgical instrument with force-feedback capabilities
US8708213B2 (en) 2006-01-31 2014-04-29 Ethicon Endo-Surgery, Inc. Surgical instrument having a feedback system
US8292155B2 (en) 2006-01-31 2012-10-23 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting and fastening instrument with tactile position feedback
US9370358B2 (en) 2006-01-31 2016-06-21 Ethicon Endo-Surgery, Llc Motor-driven surgical cutting and fastening instrument with tactile position feedback
US9320520B2 (en) 2006-01-31 2016-04-26 Ethicon Endo-Surgery, Inc. Surgical instrument system
US8167185B2 (en) 2006-01-31 2012-05-01 Ethicon Endo-Surgery, Inc. Surgical instrument having recording capabilities
US9326769B2 (en) 2006-01-31 2016-05-03 Ethicon Endo-Surgery, Llc Surgical instrument
US9149274B2 (en) 2006-03-23 2015-10-06 Ethicon Endo-Surgery, Inc. Articulating endoscopic accessory channel
US8992422B2 (en) 2006-03-23 2015-03-31 Ethicon Endo-Surgery, Inc. Robotically-controlled endoscopic accessory channel
US8911471B2 (en) 2006-03-23 2014-12-16 Ethicon Endo-Surgery, Inc. Articulatable surgical device
US9492167B2 (en) 2006-03-23 2016-11-15 Ethicon Endo-Surgery, Llc Articulatable surgical device with rotary driven cutting member
US9301759B2 (en) 2006-03-23 2016-04-05 Ethicon Endo-Surgery, Llc Robotically-controlled surgical instrument with selectively articulatable end effector
US9402626B2 (en) 2006-03-23 2016-08-02 Ethicon Endo-Surgery, Llc Rotary actuatable surgical fastener and cutter
US8721630B2 (en) 2006-03-23 2014-05-13 Ethicon Endo-Surgery, Inc. Methods and devices for controlling articulation
US8236010B2 (en) 2006-03-23 2012-08-07 Ethicon Endo-Surgery, Inc. Surgical fastener and cutter with mimicking end effector
US8322455B2 (en) 2006-06-27 2012-12-04 Ethicon Endo-Surgery, Inc. Manually driven surgical cutting and fastening instrument
US9320521B2 (en) 2006-06-27 2016-04-26 Ethicon Endo-Surgery, Llc Surgical instrument
EP1884205A2 (en) 2006-08-02 2008-02-06 Ethicon Endo-Surgery, Inc. Pneumatically powered surigcal cutting and fastening instrument with replaceable power sources
EP1884205A3 (en) * 2006-08-02 2008-04-09 Ethicon Endo-Surgery, Inc. Pneumatically powered surigcal cutting and fastening instrument with replaceable power sources
US8631987B2 (en) 2006-08-02 2014-01-21 Ethicon Endo-Surgery, Inc. Pneumatically powered surgical cutting and fastening instrument with a variable control of the actuating rate of firing with mechanical power assist
WO2008016445A1 (en) * 2006-08-02 2008-02-07 Ethicon Endo-Surgery, Inc. Pneumatically powered surgical cutting and fastening instrument with replaceable power sources
US7740159B2 (en) 2006-08-02 2010-06-22 Ethicon Endo-Surgery, Inc. Pneumatically powered surgical cutting and fastening instrument with a variable control of the actuating rate of firing with mechanical power assist
US8499993B2 (en) 2006-09-29 2013-08-06 Ethicon Endo-Surgery, Inc. Surgical staple cartridge
US8220690B2 (en) 2006-09-29 2012-07-17 Ethicon Endo-Surgery, Inc. Connected surgical staples and stapling instruments for deploying the same
US8485412B2 (en) 2006-09-29 2013-07-16 Ethicon Endo-Surgery, Inc. Surgical staples having attached drivers and stapling instruments for deploying the same
US8763875B2 (en) 2006-09-29 2014-07-01 Ethicon Endo-Surgery, Inc. End effector for use with a surgical fastening instrument
US9408604B2 (en) 2006-09-29 2016-08-09 Ethicon Endo-Surgery, Llc Surgical instrument comprising a firing system including a compliant portion
US8360297B2 (en) 2006-09-29 2013-01-29 Ethicon Endo-Surgery, Inc. Surgical cutting and stapling instrument with self adjusting anvil
US9706991B2 (en) 2006-09-29 2017-07-18 Ethicon Endo-Surgery, Inc. Staple cartridge comprising staples including a lateral base
US9179911B2 (en) 2006-09-29 2015-11-10 Ethicon Endo-Surgery, Inc. End effector for use with a surgical fastening instrument
US7794475B2 (en) 2006-09-29 2010-09-14 Ethicon Endo-Surgery, Inc. Surgical staples having compressible or crushable members for securing tissue therein and stapling instruments for deploying the same
US9603595B2 (en) 2006-09-29 2017-03-28 Ethicon Endo-Surgery, Llc Surgical instrument comprising an adjustable system configured to accommodate different jaw heights
US8973804B2 (en) 2006-09-29 2015-03-10 Ethicon Endo-Surgery, Inc. Cartridge assembly having a buttressing member
US7665647B2 (en) 2006-09-29 2010-02-23 Ethicon Endo-Surgery, Inc. Surgical cutting and stapling device with closure apparatus for limiting maximum tissue compression force
US8899465B2 (en) 2006-09-29 2014-12-02 Ethicon Endo-Surgery, Inc. Staple cartridge comprising drivers for deploying a plurality of staples
US8348131B2 (en) 2006-09-29 2013-01-08 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with mechanical indicator to show levels of tissue compression
US8720766B2 (en) 2006-09-29 2014-05-13 Ethicon Endo-Surgery, Inc. Surgical stapling instruments and staples
US7966799B2 (en) 2006-09-29 2011-06-28 Ethicon Endo-Surgery, Inc. Method of manufacturing staples
US8365976B2 (en) 2006-09-29 2013-02-05 Ethicon Endo-Surgery, Inc. Surgical staples having dissolvable, bioabsorbable or biofragmentable portions and stapling instruments for deploying the same
WO2008051734A2 (en) * 2006-10-23 2008-05-02 Boston Scientific Limited Device for circulating heated fluid
WO2008051734A3 (en) * 2006-10-23 2008-06-12 Boston Scient Scimed Inc Device for circulating heated fluid
US8226635B2 (en) 2006-10-23 2012-07-24 Boston Scientific Scimed, Inc. Device for circulating heated fluid
US7738971B2 (en) 2007-01-10 2010-06-15 Ethicon Endo-Surgery, Inc. Post-sterilization programming of surgical instruments
US8840603B2 (en) 2007-01-10 2014-09-23 Ethicon Endo-Surgery, Inc. Surgical instrument with wireless communication between control unit and sensor transponders
US9757123B2 (en) 2007-01-10 2017-09-12 Ethicon Llc Powered surgical instrument having a transmission system
US8684253B2 (en) 2007-01-10 2014-04-01 Ethicon Endo-Surgery, Inc. Surgical instrument with wireless communication between a control unit of a robotic system and remote sensor
US7721936B2 (en) 2007-01-10 2010-05-25 Ethicon Endo-Surgery, Inc. Interlock and surgical instrument including same
US7721931B2 (en) 2007-01-10 2010-05-25 Ethicon Endo-Surgery, Inc. Prevention of cartridge reuse in a surgical instrument
US8652120B2 (en) 2007-01-10 2014-02-18 Ethicon Endo-Surgery, Inc. Surgical instrument with wireless communication between control unit and sensor transponders
US8479969B2 (en) 2007-01-10 2013-07-09 Ethicon Endo-Surgery, Inc. Drive interface for operably coupling a manipulatable surgical tool to a robot
US7900805B2 (en) 2007-01-10 2011-03-08 Ethicon Endo-Surgery, Inc. Surgical instrument with enhanced battery performance
US8746530B2 (en) 2007-01-10 2014-06-10 Ethicon Endo-Surgery, Inc. Surgical instrument with wireless communication between control unit and remote sensor
US8632535B2 (en) 2007-01-10 2014-01-21 Ethicon Endo-Surgery, Inc. Interlock and surgical instrument including same
US7954682B2 (en) 2007-01-10 2011-06-07 Ethicon Endo-Surgery, Inc. Surgical instrument with elements to communicate between control unit and end effector
US8459520B2 (en) 2007-01-10 2013-06-11 Ethicon Endo-Surgery, Inc. Surgical instrument with wireless communication between control unit and remote sensor
US8517243B2 (en) 2007-01-10 2013-08-27 Ethicon Endo-Surgery, Inc. Surgical instrument with wireless communication between control unit and remote sensor
US9750501B2 (en) 2007-01-11 2017-09-05 Ethicon Endo-Surgery, Llc Surgical stapling devices having laterally movable anvils
US8540128B2 (en) 2007-01-11 2013-09-24 Ethicon Endo-Surgery, Inc. Surgical stapling device with a curved end effector
US9730692B2 (en) 2007-01-11 2017-08-15 Ethicon Llc Surgical stapling device with a curved staple cartridge
US8827133B2 (en) 2007-01-11 2014-09-09 Ethicon Endo-Surgery, Inc. Surgical stapling device having supports for a flexible drive mechanism
US9724091B2 (en) 2007-01-11 2017-08-08 Ethicon Llc Surgical stapling device
US9700321B2 (en) 2007-01-11 2017-07-11 Ethicon Llc Surgical stapling device having supports for a flexible drive mechanism
US8701958B2 (en) 2007-01-11 2014-04-22 Ethicon Endo-Surgery, Inc. Curved end effector for a surgical stapling device
US9675355B2 (en) 2007-01-11 2017-06-13 Ethicon Llc Surgical stapling device with a curved end effector
US9655624B2 (en) 2007-01-11 2017-05-23 Ethicon Llc Surgical stapling device with a curved end effector
US9603598B2 (en) 2007-01-11 2017-03-28 Ethicon Endo-Surgery, Llc Surgical stapling device with a curved end effector
US9775613B2 (en) 2007-01-11 2017-10-03 Ethicon Llc Surgical stapling device with a curved end effector
US9757130B2 (en) 2007-02-28 2017-09-12 Ethicon Llc Stapling assembly for forming different formed staple heights
US8056787B2 (en) 2007-03-28 2011-11-15 Ethicon Endo-Surgery, Inc. Surgical stapling and cutting instrument with travel-indicating retraction member
US8893946B2 (en) 2007-03-28 2014-11-25 Ethicon Endo-Surgery, Inc. Laparoscopic tissue thickness and clamp load measuring devices
US7810693B2 (en) 2007-05-30 2010-10-12 Ethicon Endo-Surgery, Inc. Surgical stapling and cutting instrument with articulatable end effector
US7798386B2 (en) 2007-05-30 2010-09-21 Ethicon Endo-Surgery, Inc. Surgical instrument articulation joint cover
US8157145B2 (en) 2007-05-31 2012-04-17 Ethicon Endo-Surgery, Inc. Pneumatically powered surgical cutting and fastening instrument with electrical feedback
US7832408B2 (en) 2007-06-04 2010-11-16 Ethicon Endo-Surgery, Inc. Surgical instrument having a directional switching mechanism
US8931682B2 (en) 2007-06-04 2015-01-13 Ethicon Endo-Surgery, Inc. Robotically-controlled shaft based rotary drive systems for surgical instruments
US8534528B2 (en) 2007-06-04 2013-09-17 Ethicon Endo-Surgery, Inc. Surgical instrument having a multiple rate directional switching mechanism
US7819299B2 (en) 2007-06-04 2010-10-26 Ethicon Endo-Surgery, Inc. Surgical instrument having a common trigger for actuating an end effector closing system and a staple firing system
US9186143B2 (en) 2007-06-04 2015-11-17 Ethicon Endo-Surgery, Inc. Robotically-controlled shaft based rotary drive systems for surgical instruments
US8424740B2 (en) 2007-06-04 2013-04-23 Ethicon Endo-Surgery, Inc. Surgical instrument having a directional switching mechanism
US7905380B2 (en) 2007-06-04 2011-03-15 Ethicon Endo-Surgery, Inc. Surgical instrument having a multiple rate directional switching mechanism
US9585658B2 (en) 2007-06-04 2017-03-07 Ethicon Endo-Surgery, Llc Stapling systems
US8616431B2 (en) 2007-06-04 2013-12-31 Ethicon Endo-Surgery, Inc. Shiftable drive interface for robotically-controlled surgical tool
US9795381B2 (en) 2007-06-04 2017-10-24 Ethicon Endo-Surgery, Llc Robotically-controlled shaft based rotary drive systems for surgical instruments
US8196796B2 (en) 2007-06-04 2012-06-12 Ethicon Endo-Surgery, Inc. Shaft based rotary drive system for surgical instruments
US9750498B2 (en) 2007-06-04 2017-09-05 Ethicon Endo Surgery, Llc Drive systems for surgical instruments
US7731072B2 (en) 2007-06-18 2010-06-08 Ethicon Endo-Surgery, Inc. Surgical stapling and cutting instrument with improved anvil opening features
US7658311B2 (en) 2007-06-22 2010-02-09 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with a geared return mechanism
US8308040B2 (en) 2007-06-22 2012-11-13 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with an articulatable end effector
US9662110B2 (en) 2007-06-22 2017-05-30 Ethicon Endo-Surgery, Llc Surgical stapling instrument with an articulatable end effector
US9138225B2 (en) 2007-06-22 2015-09-22 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with an articulatable end effector
US8408439B2 (en) 2007-06-22 2013-04-02 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with an articulatable end effector
US8333313B2 (en) 2007-06-22 2012-12-18 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with a firing member return mechanism
US8322589B2 (en) 2007-06-22 2012-12-04 Ethicon Endo-Surgery, Inc. Surgical stapling instruments
US7954684B2 (en) 2007-06-22 2011-06-07 Ehticon Endo-Surgery, Inc. Surgical stapling instrument with a firing member return mechanism
US8353437B2 (en) 2007-06-22 2013-01-15 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with a geared return mechanism
US7753245B2 (en) 2007-06-22 2010-07-13 Ethicon Endo-Surgery, Inc. Surgical stapling instruments
US9872682B2 (en) 2007-06-29 2018-01-23 Ethicon Llc Surgical stapling instrument having a releasable buttress material
US7735703B2 (en) 2007-06-29 2010-06-15 Ethicon Endo-Surgery, Inc. Re-loadable surgical stapling instrument
US8672208B2 (en) 2007-06-29 2014-03-18 Ethicon Endo-Surgery, Inc. Surgical stapling instrument having a releasable buttress material
US8668130B2 (en) 2007-06-29 2014-03-11 Ethicon Endo-Surgery, Inc. Surgical stapling systems and staple cartridges for deploying surgical staples with tissue compression features
US7669747B2 (en) 2007-06-29 2010-03-02 Ethicon Endo-Surgery, Inc. Washer for use with a surgical stapling instrument
US8991676B2 (en) 2007-06-29 2015-03-31 Ethicon Endo-Surgery, Inc. Surgical staple having a slidable crown
US8186560B2 (en) 2007-06-29 2012-05-29 Ethicon Endo-Surgery, Inc. Surgical stapling systems and staple cartridges for deploying surgical staples with tissue compression features
US8727197B2 (en) 2007-06-29 2014-05-20 Ethicon Endo-Surgery, Inc. Staple cartridge cavity configuration with cooperative surgical staple
US8925788B2 (en) 2007-06-29 2015-01-06 Ethicon Endo-Surgery, Inc. End effectors for surgical stapling instruments
US9289206B2 (en) 2007-06-29 2016-03-22 Ethicon Endo-Surgery, Llc Lateral securement members for surgical staple cartridges
US8590762B2 (en) 2007-06-29 2013-11-26 Ethicon Endo-Surgery, Inc. Staple cartridge cavity configurations
US7673782B2 (en) 2007-06-29 2010-03-09 Ethicon Endo-Surgery, Inc. Surgical stapling instrument having a releasable buttress material
EP2170459A4 (en) * 2007-07-12 2010-09-29 Asthmatx Inc Systems and methods for delivering energy to passageways in a patient
EP2170459A1 (en) * 2007-07-12 2010-04-07 Asthmatx, Inc. Systems and methods for delivering energy to passageways in a patient
US8561870B2 (en) 2008-02-13 2013-10-22 Ethicon Endo-Surgery, Inc. Surgical stapling instrument
US8453908B2 (en) 2008-02-13 2013-06-04 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with improved firing trigger arrangement
US7766209B2 (en) 2008-02-13 2010-08-03 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with improved firing trigger arrangement
US8540129B2 (en) 2008-02-13 2013-09-24 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with improved firing trigger arrangement
US9687231B2 (en) 2008-02-13 2017-06-27 Ethicon Llc Surgical stapling instrument
US9084601B2 (en) 2008-02-14 2015-07-21 Ethicon Endo-Surgery, Inc. Detachable motor powered surgical instrument
US7810692B2 (en) 2008-02-14 2010-10-12 Ethicon Endo-Surgery, Inc. Disposable loading unit with firing indicator
US8752749B2 (en) 2008-02-14 2014-06-17 Ethicon Endo-Surgery, Inc. Robotically-controlled disposable motor-driven loading unit
US8459525B2 (en) 2008-02-14 2013-06-11 Ethicon Endo-Sugery, Inc. Motorized surgical cutting and fastening instrument having a magnetic drive train torque limiting device
US7793812B2 (en) 2008-02-14 2010-09-14 Ethicon Endo-Surgery, Inc. Disposable motor-driven loading unit for use with a surgical cutting and stapling apparatus
US8113410B2 (en) 2008-02-14 2012-02-14 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with control features
US7819298B2 (en) 2008-02-14 2010-10-26 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with control features operable with one hand
US8196795B2 (en) 2008-02-14 2012-06-12 Ethicon Endo-Surgery, Inc. Disposable motor-driven loading unit for use with a surgical cutting and stapling apparatus
US9072515B2 (en) 2008-02-14 2015-07-07 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus
US8657174B2 (en) 2008-02-14 2014-02-25 Ethicon Endo-Surgery, Inc. Motorized surgical cutting and fastening instrument having handle based power source
US7819296B2 (en) 2008-02-14 2010-10-26 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with retractable firing systems
US7819297B2 (en) 2008-02-14 2010-10-26 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with reprocessible handle assembly
US8657178B2 (en) 2008-02-14 2014-02-25 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus
US9901345B2 (en) 2008-02-14 2018-02-27 Ethicon Llc Stapling assembly
US9877723B2 (en) 2008-02-14 2018-01-30 Ethicon Llc Surgical stapling assembly comprising a selector arrangement
US9901346B2 (en) 2008-02-14 2018-02-27 Ethicon Llc Stapling assembly
US7857185B2 (en) 2008-02-14 2010-12-28 Ethicon Endo-Surgery, Inc. Disposable loading unit for surgical stapling apparatus
US8636736B2 (en) 2008-02-14 2014-01-28 Ethicon Endo-Surgery, Inc. Motorized surgical cutting and fastening instrument
US8998058B2 (en) 2008-02-14 2015-04-07 Ethicon Endo-Surgery, Inc. Detachable motor powered surgical instrument
US9211121B2 (en) 2008-02-14 2015-12-15 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus
US7861906B2 (en) 2008-02-14 2011-01-04 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with articulatable components
US7866527B2 (en) 2008-02-14 2011-01-11 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with interlockable firing system
US8622274B2 (en) 2008-02-14 2014-01-07 Ethicon Endo-Surgery, Inc. Motorized cutting and fastening instrument having control circuit for optimizing battery usage
US8991677B2 (en) 2008-02-14 2015-03-31 Ethicon Endo-Surgery, Inc. Detachable motor powered surgical instrument
US9522029B2 (en) 2008-02-14 2016-12-20 Ethicon Endo-Surgery, Llc Motorized surgical cutting and fastening instrument having handle based power source
US9901344B2 (en) 2008-02-14 2018-02-27 Ethicon Llc Stapling assembly
US9867618B2 (en) 2008-02-14 2018-01-16 Ethicon Llc Surgical stapling apparatus including firing force regulation
US9204878B2 (en) 2008-02-14 2015-12-08 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with interlockable firing system
US9095339B2 (en) 2008-02-14 2015-08-04 Ethicon Endo-Surgery, Inc. Detachable motor powered surgical instrument
US7913891B2 (en) 2008-02-14 2011-03-29 Ethicon Endo-Surgery, Inc. Disposable loading unit with user feedback features and surgical instrument for use therewith
US9872684B2 (en) 2008-02-14 2018-01-23 Ethicon Llc Surgical stapling apparatus including firing force regulation
US9179912B2 (en) 2008-02-14 2015-11-10 Ethicon Endo-Surgery, Inc. Robotically-controlled motorized surgical cutting and fastening instrument
US8973803B2 (en) 2008-02-14 2015-03-10 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with control features operable with one hand
US8584919B2 (en) 2008-02-14 2013-11-19 Ethicon Endo-Sugery, Inc. Surgical stapling apparatus with load-sensitive firing mechanism
US8573465B2 (en) 2008-02-14 2013-11-05 Ethicon Endo-Surgery, Inc. Robotically-controlled surgical end effector system with rotary actuated closure systems
US8875971B2 (en) 2008-02-14 2014-11-04 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with interlockable firing system
US8573461B2 (en) 2008-02-14 2013-11-05 Ethicon Endo-Surgery, Inc. Surgical stapling instruments with cam-driven staple deployment arrangements
US8540130B2 (en) 2008-02-14 2013-09-24 Ethicon Endo-Surgery, Inc. Disposable motor-driven loading unit for use with a surgical cutting and stapling apparatus
US9498219B2 (en) 2008-02-14 2016-11-22 Ethicon Endo-Surgery, Llc Detachable motor powered surgical instrument
US8758391B2 (en) 2008-02-14 2014-06-24 Ethicon Endo-Surgery, Inc. Interchangeable tools for surgical instruments
US8608044B2 (en) 2008-02-15 2013-12-17 Ethicon Endo-Surgery, Inc. Feedback and lockout mechanism for surgical instrument
US7959051B2 (en) 2008-02-15 2011-06-14 Ethicon Endo-Surgery, Inc. Closure systems for a surgical cutting and stapling instrument
US9770245B2 (en) 2008-02-15 2017-09-26 Ethicon Llc Layer arrangements for surgical staple cartridges
US8875972B2 (en) 2008-02-15 2014-11-04 Ethicon Endo-Surgery, Inc. End effector coupling arrangements for a surgical cutting and stapling instrument
US7980443B2 (en) 2008-02-15 2011-07-19 Ethicon Endo-Surgery, Inc. End effectors for a surgical cutting and stapling instrument
US8371491B2 (en) 2008-02-15 2013-02-12 Ethicon Endo-Surgery, Inc. Surgical end effector having buttress retention features
US9585657B2 (en) 2008-02-15 2017-03-07 Ethicon Endo-Surgery, Llc Actuator for releasing a layer of material from a surgical end effector
US9913647B2 (en) 2008-02-15 2018-03-13 Ethicon Llc Disposable loading unit for use with a surgical instrument
US9839429B2 (en) 2008-02-15 2017-12-12 Ethicon Endo-Surgery, Llc Stapling system comprising a lockout
US7922061B2 (en) 2008-05-21 2011-04-12 Ethicon Endo-Surgery, Inc. Surgical instrument with automatically reconfigurable articulating end effector
US8083120B2 (en) 2008-09-18 2011-12-27 Ethicon Endo-Surgery, Inc. End effector for use with a surgical cutting and stapling instrument
US7837080B2 (en) 2008-09-18 2010-11-23 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with device for indicating when the instrument has cut through tissue
US8205781B2 (en) 2008-09-19 2012-06-26 Ethicon Endo-Surgery, Inc. Surgical stapler with apparatus for adjusting staple height
US9326771B2 (en) 2008-09-19 2016-05-03 Ethicon Endo-Surgery, Llc Staple cartridge
US7857186B2 (en) 2008-09-19 2010-12-28 Ethicon Endo-Surgery, Inc. Surgical stapler having an intermediate closing position
US9289210B2 (en) 2008-09-19 2016-03-22 Ethicon Endo-Surgery, Llc Surgical stapler with apparatus for adjusting staple height
US7905381B2 (en) 2008-09-19 2011-03-15 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with cutting member arrangement
US7832612B2 (en) 2008-09-19 2010-11-16 Ethicon Endo-Surgery, Inc. Lockout arrangement for a surgical stapler
US7954686B2 (en) 2008-09-19 2011-06-07 Ethicon Endo-Surgery, Inc. Surgical stapler with apparatus for adjusting staple height
US8540133B2 (en) 2008-09-19 2013-09-24 Ethicon Endo-Surgery, Inc. Staple cartridge
US9028519B2 (en) 2008-09-23 2015-05-12 Ethicon Endo-Surgery, Inc. Motorized surgical instrument
US9005230B2 (en) 2008-09-23 2015-04-14 Ethicon Endo-Surgery, Inc. Motorized surgical instrument
US9549732B2 (en) 2008-09-23 2017-01-24 Ethicon Endo-Surgery, Llc Motor-driven surgical cutting instrument
US8602288B2 (en) 2008-09-23 2013-12-10 Ethicon Endo-Surgery. Inc. Robotically-controlled motorized surgical end effector system with rotary actuated closure systems having variable actuation speeds
US8602287B2 (en) 2008-09-23 2013-12-10 Ethicon Endo-Surgery, Inc. Motor driven surgical cutting instrument
US9386983B2 (en) 2008-09-23 2016-07-12 Ethicon Endo-Surgery, Llc Robotically-controlled motorized surgical instrument
US9050083B2 (en) 2008-09-23 2015-06-09 Ethicon Endo-Surgery, Inc. Motorized surgical instrument
US9655614B2 (en) 2008-09-23 2017-05-23 Ethicon Endo-Surgery, Llc Robotically-controlled motorized surgical instrument with an end effector
US8210411B2 (en) 2008-09-23 2012-07-03 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting instrument
US9370364B2 (en) 2008-10-10 2016-06-21 Ethicon Endo-Surgery, Llc Powered surgical cutting and stapling apparatus with manually retractable firing system
US8608045B2 (en) 2008-10-10 2013-12-17 Ethicon Endo-Sugery, Inc. Powered surgical cutting and stapling apparatus with manually retractable firing system
US8020743B2 (en) 2008-10-15 2011-09-20 Ethicon Endo-Surgery, Inc. Powered articulatable surgical cutting and fastening instrument with flexible drive member
US7918377B2 (en) 2008-10-16 2011-04-05 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with apparatus for providing anvil position feedback
US8485413B2 (en) 2009-02-05 2013-07-16 Ethicon Endo-Surgery, Inc. Surgical stapling instrument comprising an articulation joint
US8414577B2 (en) 2009-02-05 2013-04-09 Ethicon Endo-Surgery, Inc. Surgical instruments and components for use in sterile environments
US8397971B2 (en) 2009-02-05 2013-03-19 Ethicon Endo-Surgery, Inc. Sterilizable surgical instrument
US8517239B2 (en) 2009-02-05 2013-08-27 Ethicon Endo-Surgery, Inc. Surgical stapling instrument comprising a magnetic element driver
US8453907B2 (en) 2009-02-06 2013-06-04 Ethicon Endo-Surgery, Inc. Motor driven surgical fastener device with cutting member reversing mechanism
US8444036B2 (en) 2009-02-06 2013-05-21 Ethicon Endo-Surgery, Inc. Motor driven surgical fastener device with mechanisms for adjusting a tissue gap within the end effector
US9393015B2 (en) 2009-02-06 2016-07-19 Ethicon Endo-Surgery, Llc Motor driven surgical fastener device with cutting member reversing mechanism
US9486214B2 (en) 2009-02-06 2016-11-08 Ethicon Endo-Surgery, Llc Motor driven surgical fastener device with switching system configured to prevent firing initiation until activated
US8066167B2 (en) 2009-03-23 2011-11-29 Ethicon Endo-Surgery, Inc. Circular surgical stapling instrument with anvil locking system
US8348129B2 (en) 2009-10-09 2013-01-08 Ethicon Endo-Surgery, Inc. Surgical stapler having a closure mechanism
US8141762B2 (en) 2009-10-09 2012-03-27 Ethicon Endo-Surgery, Inc. Surgical stapler comprising a staple pocket
US8899466B2 (en) 2009-11-19 2014-12-02 Ethicon Endo-Surgery, Inc. Devices and methods for introducing a surgical circular stapling instrument into a patient
US8353438B2 (en) 2009-11-19 2013-01-15 Ethicon Endo-Surgery, Inc. Circular stapler introducer with rigid cap assembly configured for easy removal
US8622275B2 (en) 2009-11-19 2014-01-07 Ethicon Endo-Surgery, Inc. Circular stapler introducer with rigid distal end portion
US8353439B2 (en) 2009-11-19 2013-01-15 Ethicon Endo-Surgery, Inc. Circular stapler introducer with radially-openable distal end portion
US8136712B2 (en) 2009-12-10 2012-03-20 Ethicon Endo-Surgery, Inc. Surgical stapler with discrete staple height adjustment and tactile feedback
US9675372B2 (en) 2009-12-24 2017-06-13 Ethicon Llc Motor-driven surgical cutting instrument with electric actuator directional control assembly
US8851354B2 (en) 2009-12-24 2014-10-07 Ethicon Endo-Surgery, Inc. Surgical cutting instrument that analyzes tissue thickness
US8453914B2 (en) 2009-12-24 2013-06-04 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting instrument with electric actuator directional control assembly
US8220688B2 (en) 2009-12-24 2012-07-17 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting instrument with electric actuator directional control assembly
US9307987B2 (en) 2009-12-24 2016-04-12 Ethicon Endo-Surgery, Llc Surgical cutting instrument that analyzes tissue thickness
US8267300B2 (en) 2009-12-30 2012-09-18 Ethicon Endo-Surgery, Inc. Dampening device for endoscopic surgical stapler
US9585660B2 (en) 2010-01-07 2017-03-07 Ethicon Endo-Surgery, Llc Method for testing a surgical tool
US8608046B2 (en) 2010-01-07 2013-12-17 Ethicon Endo-Surgery, Inc. Test device for a surgical tool
US8801735B2 (en) 2010-07-30 2014-08-12 Ethicon Endo-Surgery, Inc. Surgical circular stapler with tissue retention arrangements
US9597075B2 (en) 2010-07-30 2017-03-21 Ethicon Endo-Surgery, Inc. Tissue acquisition arrangements and methods for surgical stapling devices
US8801734B2 (en) 2010-07-30 2014-08-12 Ethicon Endo-Surgery, Inc. Circular stapling instruments with secondary cutting arrangements and methods of using same
US8789740B2 (en) 2010-07-30 2014-07-29 Ethicon Endo-Surgery, Inc. Linear cutting and stapling device with selectively disengageable cutting member
US8783543B2 (en) 2010-07-30 2014-07-22 Ethicon Endo-Surgery, Inc. Tissue acquisition arrangements and methods for surgical stapling devices
US8672207B2 (en) 2010-07-30 2014-03-18 Ethicon Endo-Surgery, Inc. Transwall visualization arrangements and methods for surgical circular staplers
US9232945B2 (en) 2010-09-09 2016-01-12 Ethicon Endo-Surgery, Inc. Surgical stapling head assembly with firing lockout for a surgical stapler
US8794497B2 (en) 2010-09-09 2014-08-05 Ethicon Endo-Surgery, Inc. Surgical stapling head assembly with firing lockout for a surgical stapler
US8360296B2 (en) 2010-09-09 2013-01-29 Ethicon Endo-Surgery, Inc. Surgical stapling head assembly with firing lockout for a surgical stapler
US8632525B2 (en) 2010-09-17 2014-01-21 Ethicon Endo-Surgery, Inc. Power control arrangements for surgical instruments and batteries
US9289212B2 (en) 2010-09-17 2016-03-22 Ethicon Endo-Surgery, Inc. Surgical instruments and batteries for surgical instruments
US8789741B2 (en) 2010-09-24 2014-07-29 Ethicon Endo-Surgery, Inc. Surgical instrument with trigger assembly for generating multiple actuation motions
US9131940B2 (en) 2010-09-29 2015-09-15 Ethicon Endo-Surgery, Inc. Staple cartridge
US8733613B2 (en) 2010-09-29 2014-05-27 Ethicon Endo-Surgery, Inc. Staple cartridge
US9592053B2 (en) 2010-09-30 2017-03-14 Ethicon Endo-Surgery, Llc Staple cartridge comprising multiple regions
US8740038B2 (en) 2010-09-30 2014-06-03 Ethicon Endo-Surgery, Inc. Staple cartridge comprising a releasable portion
US9277919B2 (en) 2010-09-30 2016-03-08 Ethicon Endo-Surgery, Llc Tissue thickness compensator comprising fibers to produce a resilient load
US9924947B2 (en) 2010-09-30 2018-03-27 Ethicon Llc Staple cartridge comprising a compressible portion
US9272406B2 (en) 2010-09-30 2016-03-01 Ethicon Endo-Surgery, Llc Fastener cartridge comprising a cutting member for releasing a tissue thickness compensator
US9801634B2 (en) 2010-09-30 2017-10-31 Ethicon Llc Tissue thickness compensator for a surgical stapler
US9282962B2 (en) 2010-09-30 2016-03-15 Ethicon Endo-Surgery, Llc Adhesive film laminate
US8740034B2 (en) 2010-09-30 2014-06-03 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with interchangeable staple cartridge arrangements
US9232941B2 (en) 2010-09-30 2016-01-12 Ethicon Endo-Surgery, Inc. Tissue thickness compensator comprising a reservoir
US9700317B2 (en) 2010-09-30 2017-07-11 Ethicon Endo-Surgery, Llc Fastener cartridge comprising a releasable tissue thickness compensator
US9814462B2 (en) 2010-09-30 2017-11-14 Ethicon Llc Assembly for fastening tissue comprising a compressible layer
US9826978B2 (en) 2010-09-30 2017-11-28 Ethicon Llc End effectors with same side closure and firing motions
US9295464B2 (en) 2010-09-30 2016-03-29 Ethicon Endo-Surgery, Inc. Surgical stapler anvil comprising a plurality of forming pockets
US9301755B2 (en) 2010-09-30 2016-04-05 Ethicon Endo-Surgery, Llc Compressible staple cartridge assembly
US9044228B2 (en) 2010-09-30 2015-06-02 Ethicon Endo-Surgery, Inc. Fastener system comprising a plurality of fastener cartridges
US9301753B2 (en) 2010-09-30 2016-04-05 Ethicon Endo-Surgery, Llc Expandable tissue thickness compensator
US9301752B2 (en) 2010-09-30 2016-04-05 Ethicon Endo-Surgery, Llc Tissue thickness compensator comprising a plurality of capsules
US9833242B2 (en) 2010-09-30 2017-12-05 Ethicon Endo-Surgery, Llc Tissue thickness compensators
US9307965B2 (en) 2010-09-30 2016-04-12 Ethicon Endo-Surgery, Llc Tissue stapler having a thickness compensator incorporating an anti-microbial agent
US9572574B2 (en) 2010-09-30 2017-02-21 Ethicon Endo-Surgery, Llc Tissue thickness compensators comprising therapeutic agents
US8814024B2 (en) 2010-09-30 2014-08-26 Ethicon Endo-Surgery, Inc. Fastener system comprising a plurality of connected retention matrix elements
US9220501B2 (en) 2010-09-30 2015-12-29 Ethicon Endo-Surgery, Inc. Tissue thickness compensators
US8746535B2 (en) 2010-09-30 2014-06-10 Ethicon Endo-Surgery, Inc. Tissue thickness compensator comprising detachable portions
US9314246B2 (en) 2010-09-30 2016-04-19 Ethicon Endo-Surgery, Llc Tissue stapler having a thickness compensator incorporating an anti-inflammatory agent
US9220500B2 (en) 2010-09-30 2015-12-29 Ethicon Endo-Surgery, Inc. Tissue thickness compensator comprising structure to produce a resilient load
US9320518B2 (en) 2010-09-30 2016-04-26 Ethicon Endo-Surgery, Llc Tissue stapler having a thickness compensator incorporating an oxygen generating agent
US9848875B2 (en) 2010-09-30 2017-12-26 Ethicon Llc Anvil layer attached to a proximal end of an end effector
US9566061B2 (en) 2010-09-30 2017-02-14 Ethicon Endo-Surgery, Llc Fastener cartridge comprising a releasably attached tissue thickness compensator
US8474677B2 (en) 2010-09-30 2013-07-02 Ethicon Endo-Surgery, Inc. Fastener system comprising a retention matrix and a cover
US9044227B2 (en) 2010-09-30 2015-06-02 Ethicon Endo-Surgery, Inc. Collapsible fastener cartridge
US9795383B2 (en) 2010-09-30 2017-10-24 Ethicon Llc Tissue thickness compensator comprising resilient members
US9033203B2 (en) 2010-09-30 2015-05-19 Ethicon Endo-Surgery, Inc. Fastening instrument for deploying a fastener system comprising a retention matrix
US9113862B2 (en) 2010-09-30 2015-08-25 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with a variable staple forming system
US8899463B2 (en) 2010-09-30 2014-12-02 Ethicon Endo-Surgery, Inc. Surgical staple cartridges supporting non-linearly arranged staples and surgical stapling instruments with common staple-forming pockets
US8393514B2 (en) 2010-09-30 2013-03-12 Ethicon Endo-Surgery, Inc. Selectively orientable implantable fastener cartridge
US9332974B2 (en) 2010-09-30 2016-05-10 Ethicon Endo-Surgery, Llc Layered tissue thickness compensator
US8529600B2 (en) 2010-09-30 2013-09-10 Ethicon Endo-Surgery, Inc. Fastener system comprising a retention matrix
US9345477B2 (en) 2010-09-30 2016-05-24 Ethicon Endo-Surgery, Llc Tissue stapler having a thickness compensator comprising incorporating a hemostatic agent
US8752699B2 (en) 2010-09-30 2014-06-17 Ethicon Endo-Surgery, Inc. Implantable fastener cartridge comprising bioabsorbable layers
US8757465B2 (en) 2010-09-30 2014-06-24 Ethicon Endo-Surgery, Inc. Fastener system comprising a retention matrix and an alignment matrix
US9016542B2 (en) 2010-09-30 2015-04-28 Ethicon Endo-Surgery, Inc. Staple cartridge comprising compressible distortion resistant components
US9358005B2 (en) 2010-09-30 2016-06-07 Ethicon Endo-Surgery, Llc End effector layer including holding features
US8978954B2 (en) 2010-09-30 2015-03-17 Ethicon Endo-Surgery, Inc. Staple cartridge comprising an adjustable distal portion
US9364233B2 (en) 2010-09-30 2016-06-14 Ethicon Endo-Surgery, Llc Tissue thickness compensators for circular surgical staplers
US8763877B2 (en) 2010-09-30 2014-07-01 Ethicon Endo-Surgery, Inc. Surgical instruments with reconfigurable shaft segments
US8657176B2 (en) 2010-09-30 2014-02-25 Ethicon Endo-Surgery, Inc. Tissue thickness compensator for a surgical stapler
US8978956B2 (en) 2010-09-30 2015-03-17 Ethicon Endo-Surgery, Inc. Jaw closure arrangements for surgical instruments
US9386988B2 (en) 2010-09-30 2016-07-12 Ethicon End-Surgery, LLC Retainer assembly including a tissue thickness compensator
US8925782B2 (en) 2010-09-30 2015-01-06 Ethicon Endo-Surgery, Inc. Implantable fastener cartridge comprising multiple layers
US8777004B2 (en) 2010-09-30 2014-07-15 Ethicon Endo-Surgery, Inc. Compressible staple cartridge comprising alignment members
US9883861B2 (en) 2010-09-30 2018-02-06 Ethicon Llc Retainer assembly including a tissue thickness compensator
US9788834B2 (en) 2010-09-30 2017-10-17 Ethicon Llc Layer comprising deployable attachment members
US9844372B2 (en) 2010-09-30 2017-12-19 Ethicon Llc Retainer assembly including a tissue thickness compensator
US9808247B2 (en) 2010-09-30 2017-11-07 Ethicon Llc Stapling system comprising implantable layers
US8783542B2 (en) 2010-09-30 2014-07-22 Ethicon Endo-Surgery, Inc. Fasteners supported by a fastener cartridge support
US8893949B2 (en) 2010-09-30 2014-11-25 Ethicon Endo-Surgery, Inc. Surgical stapler with floating anvil
US9839420B2 (en) 2010-09-30 2017-12-12 Ethicon Llc Tissue thickness compensator comprising at least one medicament
US9433419B2 (en) 2010-09-30 2016-09-06 Ethicon Endo-Surgery, Inc. Tissue thickness compensator comprising a plurality of layers
US8864007B2 (en) 2010-09-30 2014-10-21 Ethicon Endo-Surgery, Inc. Implantable fastener cartridge having a non-uniform arrangement
US8864009B2 (en) 2010-09-30 2014-10-21 Ethicon Endo-Surgery, Inc. Tissue thickness compensator for a surgical stapler comprising an adjustable anvil
US9861361B2 (en) 2010-09-30 2018-01-09 Ethicon Llc Releasable tissue thickness compensator and fastener cartridge having the same
US9629814B2 (en) 2010-09-30 2017-04-25 Ethicon Endo-Surgery, Llc Tissue thickness compensator configured to redistribute compressive forces
US9480476B2 (en) 2010-09-30 2016-11-01 Ethicon Endo-Surgery, Llc Tissue thickness compensator comprising resilient members
US9833236B2 (en) 2010-09-30 2017-12-05 Ethicon Llc Tissue thickness compensator for surgical staplers
US8857694B2 (en) 2010-09-30 2014-10-14 Ethicon Endo-Surgery, Inc. Staple cartridge loading assembly
US9168038B2 (en) 2010-09-30 2015-10-27 Ethicon Endo-Surgery, Inc. Staple cartridge comprising a tissue thickness compensator
US8740037B2 (en) 2010-09-30 2014-06-03 Ethicon Endo-Surgery, Inc. Compressible fastener cartridge
US9113864B2 (en) 2010-09-30 2015-08-25 Ethicon Endo-Surgery, Inc. Surgical cutting and fastening instruments with separate and distinct fastener deployment and tissue cutting systems
US9113865B2 (en) 2010-09-30 2015-08-25 Ethicon Endo-Surgery, Inc. Staple cartridge comprising a layer
US9615826B2 (en) 2010-09-30 2017-04-11 Ethicon Endo-Surgery, Llc Multiple thickness implantable layers for surgical stapling devices
US8840003B2 (en) 2010-09-30 2014-09-23 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with compact articulation control arrangement
US9833238B2 (en) 2010-09-30 2017-12-05 Ethicon Endo-Surgery, Llc Retainer assembly including a tissue thickness compensator
US9592050B2 (en) 2010-09-30 2017-03-14 Ethicon Endo-Surgery, Llc End effector comprising a distal tissue abutment member
US9687236B2 (en) 2010-10-01 2017-06-27 Ethicon Endo-Surgery, Inc. Surgical instrument having a power control circuit
US8695866B2 (en) 2010-10-01 2014-04-15 Ethicon Endo-Surgery, Inc. Surgical instrument having a power control circuit
USD650074S1 (en) 2010-10-01 2011-12-06 Ethicon Endo-Surgery, Inc. Surgical instrument
US8978955B2 (en) 2011-03-14 2015-03-17 Ethicon Endo-Surgery, Inc. Anvil assemblies with collapsible frames for circular staplers
US9211122B2 (en) 2011-03-14 2015-12-15 Ethicon Endo-Surgery, Inc. Surgical access devices with anvil introduction and specimen retrieval structures
US9918704B2 (en) 2011-03-14 2018-03-20 Ethicon Llc Surgical instrument
US8734478B2 (en) 2011-03-14 2014-05-27 Ethicon Endo-Surgery, Inc. Rectal manipulation devices
US9033204B2 (en) 2011-03-14 2015-05-19 Ethicon Endo-Surgery, Inc. Circular stapling devices with tissue-puncturing anvil features
US9089330B2 (en) 2011-03-14 2015-07-28 Ethicon Endo-Surgery, Inc. Surgical bowel retractor devices
US8632462B2 (en) 2011-03-14 2014-01-21 Ethicon Endo-Surgery, Inc. Trans-rectum universal ports
US9113883B2 (en) 2011-03-14 2015-08-25 Ethicon Endo-Surgery, Inc. Collapsible anvil plate assemblies for circular surgical stapling devices
US9125654B2 (en) 2011-03-14 2015-09-08 Ethicon Endo-Surgery, Inc. Multiple part anvil assemblies for circular surgical stapling devices
US9113884B2 (en) 2011-03-14 2015-08-25 Ethicon Endo-Surgery, Inc. Modular surgical tool systems
US8858590B2 (en) 2011-03-14 2014-10-14 Ethicon Endo-Surgery, Inc. Tissue manipulation devices
US8827903B2 (en) 2011-03-14 2014-09-09 Ethicon Endo-Surgery, Inc. Modular tool heads for use with circular surgical instruments
US8857693B2 (en) 2011-03-15 2014-10-14 Ethicon Endo-Surgery, Inc. Surgical instruments with lockable articulating end effector
US8800841B2 (en) 2011-03-15 2014-08-12 Ethicon Endo-Surgery, Inc. Surgical staple cartridges
US8926598B2 (en) 2011-03-15 2015-01-06 Ethicon Endo-Surgery, Inc. Surgical instruments with articulatable and rotatable end effector
US8540131B2 (en) 2011-03-15 2013-09-24 Ethicon Endo-Surgery, Inc. Surgical staple cartridges with tissue tethers for manipulating divided tissue and methods of using same
US9044229B2 (en) 2011-03-15 2015-06-02 Ethicon Endo-Surgery, Inc. Surgical fastener instruments
US9351730B2 (en) 2011-04-29 2016-05-31 Ethicon Endo-Surgery, Llc Tissue thickness compensator comprising channels
US9211120B2 (en) 2011-04-29 2015-12-15 Ethicon Endo-Surgery, Inc. Tissue thickness compensator comprising a plurality of medicaments
US9241714B2 (en) 2011-04-29 2016-01-26 Ethicon Endo-Surgery, Inc. Tissue thickness compensator and method for making the same
US9913648B2 (en) 2011-05-27 2018-03-13 Ethicon Endo-Surgery, Llc Surgical system
US9775614B2 (en) 2011-05-27 2017-10-03 Ethicon Endo-Surgery, Llc Surgical stapling instruments with rotatable staple deployment arrangements
US9072535B2 (en) 2011-05-27 2015-07-07 Ethicon Endo-Surgery, Inc. Surgical stapling instruments with rotatable staple deployment arrangements
US9271799B2 (en) 2011-05-27 2016-03-01 Ethicon Endo-Surgery, Llc Robotic surgical system with removable motor housing
US8833632B2 (en) 2011-09-06 2014-09-16 Ethicon Endo-Surgery, Inc. Firing member displacement system for a stapling instrument
US8789739B2 (en) 2011-09-06 2014-07-29 Ethicon Endo-Surgery, Inc. Continuous stapling instrument
US9198661B2 (en) 2011-09-06 2015-12-01 Ethicon Endo-Surgery, Inc. Stapling instrument comprising a plurality of staple cartridges stored therein
US9107663B2 (en) 2011-09-06 2015-08-18 Ethicon Endo-Surgery, Inc. Stapling instrument comprising resettable staple drivers
US9687237B2 (en) 2011-09-23 2017-06-27 Ethicon Endo-Surgery, Llc Staple cartridge including collapsible deck arrangement
US9592054B2 (en) 2011-09-23 2017-03-14 Ethicon Endo-Surgery, Llc Surgical stapler with stationary staple drivers
US9055941B2 (en) 2011-09-23 2015-06-16 Ethicon Endo-Surgery, Inc. Staple cartridge including collapsible deck
US9050084B2 (en) 2011-09-23 2015-06-09 Ethicon Endo-Surgery, Inc. Staple cartridge including collapsible deck arrangement
US9216019B2 (en) 2011-09-23 2015-12-22 Ethicon Endo-Surgery, Inc. Surgical stapler with stationary staple drivers
US9044230B2 (en) 2012-02-13 2015-06-02 Ethicon Endo-Surgery, Inc. Surgical cutting and fastening instrument with apparatus for determining cartridge and firing motion status
US9730697B2 (en) 2012-02-13 2017-08-15 Ethicon Endo-Surgery, Llc Surgical cutting and fastening instrument with apparatus for determining cartridge and firing motion status
US9078653B2 (en) 2012-03-26 2015-07-14 Ethicon Endo-Surgery, Inc. Surgical stapling device with lockout system for preventing actuation in the absence of an installed staple cartridge
US9314247B2 (en) 2012-03-28 2016-04-19 Ethicon Endo-Surgery, Llc Tissue stapler having a thickness compensator incorporating a hydrophilic agent
US9307989B2 (en) 2012-03-28 2016-04-12 Ethicon Endo-Surgery, Llc Tissue stapler having a thickness compensator incorportating a hydrophobic agent
US9320523B2 (en) 2012-03-28 2016-04-26 Ethicon Endo-Surgery, Llc Tissue thickness compensator comprising tissue ingrowth features
US9918716B2 (en) 2012-03-28 2018-03-20 Ethicon Llc Staple cartridge comprising implantable layers
US9204880B2 (en) 2012-03-28 2015-12-08 Ethicon Endo-Surgery, Inc. Tissue thickness compensator comprising capsules defining a low pressure environment
US9198662B2 (en) 2012-03-28 2015-12-01 Ethicon Endo-Surgery, Inc. Tissue thickness compensator having improved visibility
US9414838B2 (en) 2012-03-28 2016-08-16 Ethicon Endo-Surgery, Llc Tissue thickness compensator comprised of a plurality of materials
US9724098B2 (en) 2012-03-28 2017-08-08 Ethicon Endo-Surgery, Llc Staple cartridge comprising an implantable layer
US9517063B2 (en) 2012-03-28 2016-12-13 Ethicon Endo-Surgery, Llc Movable member for use with a tissue thickness compensator
US9101358B2 (en) 2012-06-15 2015-08-11 Ethicon Endo-Surgery, Inc. Articulatable surgical instrument comprising a firing drive
US9226751B2 (en) 2012-06-28 2016-01-05 Ethicon Endo-Surgery, Inc. Surgical instrument system including replaceable end effectors
US9072536B2 (en) 2012-06-28 2015-07-07 Ethicon Endo-Surgery, Inc. Differential locking arrangements for rotary powered surgical instruments
US9282974B2 (en) 2012-06-28 2016-03-15 Ethicon Endo-Surgery, Llc Empty clip cartridge lockout
US9204879B2 (en) 2012-06-28 2015-12-08 Ethicon Endo-Surgery, Inc. Flexible drive member
US8747238B2 (en) 2012-06-28 2014-06-10 Ethicon Endo-Surgery, Inc. Rotary drive shaft assemblies for surgical instruments with articulatable end effectors
US9907620B2 (en) 2012-06-28 2018-03-06 Ethicon Endo-Surgery, Llc Surgical end effectors having angled tissue-contacting surfaces
US9028494B2 (en) 2012-06-28 2015-05-12 Ethicon Endo-Surgery, Inc. Interchangeable end effector coupling arrangement
US9649111B2 (en) 2012-06-28 2017-05-16 Ethicon Endo-Surgery, Llc Replaceable clip cartridge for a clip applier
US9364230B2 (en) 2012-06-28 2016-06-14 Ethicon Endo-Surgery, Llc Surgical stapling instruments with rotary joint assemblies
US9408606B2 (en) 2012-06-28 2016-08-09 Ethicon Endo-Surgery, Llc Robotically powered surgical device with manually-actuatable reversing system
US9561038B2 (en) 2012-06-28 2017-02-07 Ethicon Endo-Surgery, Llc Interchangeable clip applier
US9125662B2 (en) 2012-06-28 2015-09-08 Ethicon Endo-Surgery, Inc. Multi-axis articulating and rotating surgical tools
US9119657B2 (en) 2012-06-28 2015-09-01 Ethicon Endo-Surgery, Inc. Rotary actuatable closure arrangement for surgical end effector
US9289256B2 (en) 2012-06-28 2016-03-22 Ethicon Endo-Surgery, Llc Surgical end effectors having angled tissue-contacting surfaces
US9101385B2 (en) 2012-06-28 2015-08-11 Ethicon Endo-Surgery, Inc. Electrode connections for rotary driven surgical tools
US9592086B2 (en) 2012-07-24 2017-03-14 Boston Scientific Scimed, Inc. Electrodes for tissue treatment
US9386985B2 (en) 2012-10-15 2016-07-12 Ethicon Endo-Surgery, Llc Surgical cutting instrument
US9386984B2 (en) 2013-02-08 2016-07-12 Ethicon Endo-Surgery, Llc Staple cartridge comprising a releasable cover
US9554794B2 (en) 2013-03-01 2017-01-31 Ethicon Endo-Surgery, Llc Multiple processor motor control for modular surgical instruments
US9468438B2 (en) 2013-03-01 2016-10-18 Eticon Endo-Surgery, LLC Sensor straightened end effector during removal through trocar
US9307986B2 (en) 2013-03-01 2016-04-12 Ethicon Endo-Surgery, Llc Surgical instrument soft stop
US9398911B2 (en) 2013-03-01 2016-07-26 Ethicon Endo-Surgery, Llc Rotary powered surgical instruments with multiple degrees of freedom
US9782169B2 (en) 2013-03-01 2017-10-10 Ethicon Llc Rotary powered articulation joints for surgical instruments
US9326767B2 (en) 2013-03-01 2016-05-03 Ethicon Endo-Surgery, Llc Joystick switch assemblies for surgical instruments
US9700309B2 (en) 2013-03-01 2017-07-11 Ethicon Llc Articulatable surgical instruments with conductive pathways for signal communication
US9358003B2 (en) 2013-03-01 2016-06-07 Ethicon Endo-Surgery, Llc Electromechanical surgical device with signal relay arrangement
US9345481B2 (en) 2013-03-13 2016-05-24 Ethicon Endo-Surgery, Llc Staple cartridge tissue thickness sensor system
US9687230B2 (en) 2013-03-14 2017-06-27 Ethicon Llc Articulatable surgical instrument comprising a firing drive
US9629623B2 (en) 2013-03-14 2017-04-25 Ethicon Endo-Surgery, Llc Drive system lockout arrangements for modular surgical instruments
US9629629B2 (en) 2013-03-14 2017-04-25 Ethicon Endo-Surgey, LLC Control systems for surgical instruments
US9883860B2 (en) 2013-03-14 2018-02-06 Ethicon Llc Interchangeable shaft assemblies for use with a surgical instrument
US9351727B2 (en) 2013-03-14 2016-05-31 Ethicon Endo-Surgery, Llc Drive train control arrangements for modular surgical instruments
US9332987B2 (en) 2013-03-14 2016-05-10 Ethicon Endo-Surgery, Llc Control arrangements for a drive member of a surgical instrument
US9808244B2 (en) 2013-03-14 2017-11-07 Ethicon Llc Sensor arrangements for absolute positioning system for surgical instruments
US9351726B2 (en) 2013-03-14 2016-05-31 Ethicon Endo-Surgery, Llc Articulation control system for articulatable surgical instruments
US9888919B2 (en) 2013-03-14 2018-02-13 Ethicon Llc Method and system for operating a surgical instrument
US9572577B2 (en) 2013-03-27 2017-02-21 Ethicon Endo-Surgery, Llc Fastener cartridge comprising a tissue thickness compensator including openings therein
US9795384B2 (en) 2013-03-27 2017-10-24 Ethicon Llc Fastener cartridge comprising a tissue thickness compensator and a gap setting element
US9332984B2 (en) 2013-03-27 2016-05-10 Ethicon Endo-Surgery, Llc Fastener cartridge assemblies
US9844368B2 (en) 2013-04-16 2017-12-19 Ethicon Llc Surgical system comprising first and second drive systems
US9649110B2 (en) 2013-04-16 2017-05-16 Ethicon Llc Surgical instrument comprising a closing drive and a firing drive operated from the same rotatable output
US9867612B2 (en) 2013-04-16 2018-01-16 Ethicon Llc Powered surgical stapler
US9801626B2 (en) 2013-04-16 2017-10-31 Ethicon Llc Modular motor driven surgical instruments with alignment features for aligning rotary drive shafts with surgical end effector shafts
US9826976B2 (en) 2013-04-16 2017-11-28 Ethicon Llc Motor driven surgical instruments with lockable dual drive shafts
US9814460B2 (en) 2013-04-16 2017-11-14 Ethicon Llc Modular motor driven surgical instruments with status indication arrangements
US9574644B2 (en) 2013-05-30 2017-02-21 Ethicon Endo-Surgery, Llc Power module for use with a surgical instrument
US9814618B2 (en) 2013-06-06 2017-11-14 Boston Scientific Scimed, Inc. Devices for delivering energy and related methods of use
US9808249B2 (en) 2013-08-23 2017-11-07 Ethicon Llc Attachment portions for surgical instrument assemblies
US9283054B2 (en) 2013-08-23 2016-03-15 Ethicon Endo-Surgery, Llc Interactive displays
US9924942B2 (en) 2013-08-23 2018-03-27 Ethicon Llc Motor-powered articulatable surgical instruments
US9510828B2 (en) 2013-08-23 2016-12-06 Ethicon Endo-Surgery, Llc Conductor arrangements for electrically powered surgical instruments with rotatable end effectors
US9700310B2 (en) 2013-08-23 2017-07-11 Ethicon Llc Firing member retraction devices for powered surgical instruments
US9775609B2 (en) 2013-08-23 2017-10-03 Ethicon Llc Tamper proof circuit for surgical instrument battery pack
US9445813B2 (en) 2013-08-23 2016-09-20 Ethicon Endo-Surgery, Llc Closure indicator systems for surgical instruments
US9585662B2 (en) 2013-12-23 2017-03-07 Ethicon Endo-Surgery, Llc Fastener cartridge comprising an extendable firing member
US9839428B2 (en) 2013-12-23 2017-12-12 Ethicon Llc Surgical cutting and stapling instruments with independent jaw control features
US9642620B2 (en) 2013-12-23 2017-05-09 Ethicon Endo-Surgery, Llc Surgical cutting and stapling instruments with articulatable end effectors
US9763662B2 (en) 2013-12-23 2017-09-19 Ethicon Llc Fastener cartridge comprising a firing member configured to directly engage and eject fasteners from the fastener cartridge
US9681870B2 (en) 2013-12-23 2017-06-20 Ethicon Llc Articulatable surgical instruments with separate and distinct closing and firing systems
US9724092B2 (en) 2013-12-23 2017-08-08 Ethicon Llc Modular surgical instruments
US9549735B2 (en) 2013-12-23 2017-01-24 Ethicon Endo-Surgery, Llc Fastener cartridge comprising a firing member including fastener transfer surfaces
US9757124B2 (en) 2014-02-24 2017-09-12 Ethicon Llc Implantable layer assemblies
US9775608B2 (en) 2014-02-24 2017-10-03 Ethicon Llc Fastening system comprising a firing member lockout
US9839422B2 (en) 2014-02-24 2017-12-12 Ethicon Llc Implantable layers and methods for altering implantable layers for use with surgical fastening instruments
US9693777B2 (en) 2014-02-24 2017-07-04 Ethicon Llc Implantable layers comprising a pressed region
US9884456B2 (en) 2014-02-24 2018-02-06 Ethicon Llc Implantable layers and methods for altering one or more properties of implantable layers for use with fastening instruments
US9839423B2 (en) 2014-02-24 2017-12-12 Ethicon Llc Implantable layers and methods for modifying the shape of the implantable layers for use with a surgical fastening instrument
US9826977B2 (en) 2014-03-26 2017-11-28 Ethicon Llc Sterilization verification circuit
US9820738B2 (en) 2014-03-26 2017-11-21 Ethicon Llc Surgical instrument comprising interactive systems
US9690362B2 (en) 2014-03-26 2017-06-27 Ethicon Llc Surgical instrument control circuit having a safety processor
US9750499B2 (en) 2014-03-26 2017-09-05 Ethicon Llc Surgical stapling instrument system
US9733663B2 (en) 2014-03-26 2017-08-15 Ethicon Llc Power management through segmented circuit and variable voltage protection
US9743929B2 (en) 2014-03-26 2017-08-29 Ethicon Llc Modular powered surgical instrument with detachable shaft assemblies
US9913642B2 (en) 2014-03-26 2018-03-13 Ethicon Llc Surgical instrument comprising a sensor system
US9730695B2 (en) 2014-03-26 2017-08-15 Ethicon Endo-Surgery, Llc Power management through segmented circuit
US9804618B2 (en) 2014-03-26 2017-10-31 Ethicon Llc Systems and methods for controlling a segmented circuit
US9833241B2 (en) 2014-04-16 2017-12-05 Ethicon Llc Surgical fastener cartridges with driver stabilizing arrangements
US9877721B2 (en) 2014-04-16 2018-01-30 Ethicon Llc Fastener cartridge comprising tissue control features
US9844369B2 (en) 2014-04-16 2017-12-19 Ethicon Llc Surgical end effectors with firing element monitoring arrangements
US9788836B2 (en) 2014-09-05 2017-10-17 Ethicon Llc Multiple motor control for powered medical device
US9757128B2 (en) 2014-09-05 2017-09-12 Ethicon Llc Multiple sensors with one sensor affecting a second sensor's output or interpretation
US9724094B2 (en) 2014-09-05 2017-08-08 Ethicon Llc Adjunct with integrated sensors to quantify tissue compression
US9737301B2 (en) 2014-09-05 2017-08-22 Ethicon Llc Monitoring device degradation based on component evaluation
US9801628B2 (en) 2014-09-26 2017-10-31 Ethicon Llc Surgical staple and driver arrangements for staple cartridges
US9801627B2 (en) 2014-09-26 2017-10-31 Ethicon Llc Fastener cartridge for creating a flexible staple line
US9924944B2 (en) 2014-10-16 2018-03-27 Ethicon Llc Staple cartridge comprising an adjunct material
US9844376B2 (en) 2014-11-06 2017-12-19 Ethicon Llc Staple cartridge comprising a releasable adjunct material
US9844374B2 (en) 2014-12-18 2017-12-19 Ethicon Llc Surgical instrument systems comprising an articulatable end effector and means for adjusting the firing stroke of a firing member
US9844375B2 (en) 2014-12-18 2017-12-19 Ethicon Llc Drive arrangements for articulatable surgical instruments
US9931118B2 (en) 2015-02-27 2018-04-03 Ethicon Endo-Surgery, Llc Reinforced battery for a surgical instrument
US9924961B2 (en) 2015-03-06 2018-03-27 Ethicon Endo-Surgery, Llc Interactive feedback system for powered surgical instruments
US9901342B2 (en) 2015-03-06 2018-02-27 Ethicon Endo-Surgery, Llc Signal and power communication system positioned on a rotatable shaft
US9895148B2 (en) 2015-03-06 2018-02-20 Ethicon Endo-Surgery, Llc Monitoring speed control and precision incrementing of motor for powered surgical instruments
US9808246B2 (en) 2015-03-06 2017-11-07 Ethicon Endo-Surgery, Llc Method of operating a powered surgical instrument

Also Published As

Publication number Publication date Type
WO2006044581A3 (en) 2006-08-03 application

Similar Documents

Publication Publication Date Title
US6190382B1 (en) Radio-frequency based catheter system for ablation of body tissues
US6241702B1 (en) Radio frequency ablation device for treatment of the prostate
US6611793B1 (en) Systems and methods to identify and disable re-use single use devices based on detecting environmental changes
US6702846B2 (en) Urological stent therapy system and method
US6651669B1 (en) Systems and methods to identify and disable re-used single use devices based on cataloging catheter usage
US7494488B2 (en) Facial tissue strengthening and tightening device and methods
US6286512B1 (en) Electrosurgical device and procedure for forming a channel within tissue
US6578579B2 (en) Systems and methods for preventing automatic identification of re-used single use devices
US5685839A (en) Ultrasound probe with thermal sensing
US6905480B2 (en) Apparatus for delivering ablation fluid to treat lesions
US7377918B2 (en) Electrosurgical method and apparatus
US20070083195A1 (en) Low power tissue ablation system
US4920978A (en) Method and apparatus for the endoscopic treatment of deep tumors using RF hyperthermia
US20080262489A1 (en) Thrombus removal
US20040215180A1 (en) Ablation of stomach lining to treat obesity
US5749846A (en) Medical probe device with optical viewing capability
US7004938B2 (en) Radio-frequency-based catheter system with improved deflection and steering mechanisms
US7588557B2 (en) Medical instrument for fluid injection and related method
US6428538B1 (en) Apparatus and method for thermal treatment of body tissue
US6447505B2 (en) Balloon catheter method for intra-urethral radio-frequency urethral enlargement
US20100286679A1 (en) Systems and Methods for Prostate Treatment
US5980519A (en) Electrocautery probe with variable morphology electrode
US20040092926A1 (en) Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue
US6743226B2 (en) Adjustable trans-urethral radio-frequency ablation
US5938658A (en) Device and methods for treating canker sores by RF ablation

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV LY MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
NENP Non-entry into the national phase in:

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 05857751

Country of ref document: EP

Kind code of ref document: A2