WO2005113419A3 - Systemes, dispositifs et procedes de relargage electrocinetique de medicament - Google Patents

Systemes, dispositifs et procedes de relargage electrocinetique de medicament Download PDF

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Publication number
WO2005113419A3
WO2005113419A3 PCT/US2005/013728 US2005013728W WO2005113419A3 WO 2005113419 A3 WO2005113419 A3 WO 2005113419A3 US 2005013728 W US2005013728 W US 2005013728W WO 2005113419 A3 WO2005113419 A3 WO 2005113419A3
Authority
WO
WIPO (PCT)
Prior art keywords
reservoir
fluid
fluid reservoir
devices
systems
Prior art date
Application number
PCT/US2005/013728
Other languages
English (en)
Other versions
WO2005113419A2 (fr
Inventor
Deon S Anex
Phillip H Paul
David W Neyer
Edwin K Hlavka
Original Assignee
Eksigent Technologies Llc
Deon S Anex
Phillip H Paul
David W Neyer
Edwin K Hlavka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eksigent Technologies Llc, Deon S Anex, Phillip H Paul, David W Neyer, Edwin K Hlavka filed Critical Eksigent Technologies Llc
Priority to EP05779953.8A priority Critical patent/EP1740497A4/fr
Priority to CA2564800A priority patent/CA2564800C/fr
Priority to CN2005800186796A priority patent/CN101365885B/zh
Priority to AU2005245347A priority patent/AU2005245347A1/en
Priority to JP2007509658A priority patent/JP4646976B2/ja
Publication of WO2005113419A2 publication Critical patent/WO2005113419A2/fr
Publication of WO2005113419A3 publication Critical patent/WO2005113419A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
    • A61M5/1483—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags using flexible bags externally pressurised by fluid pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • F04B19/006—Micropumps
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/04—Pumps having electric drive
    • F04B43/043—Micropumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M2005/14513—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/201—Glucose concentration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Dermatology (AREA)
  • External Artificial Organs (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Micromachines (AREA)
  • Electrotherapy Devices (AREA)

Abstract

Les dispositifs, systèmes et procédés de l'invention utilisent des pompes électrocinétiques capables de générer un flux à pressions hautes et basses pour diverses applications médicales, dont le relargage de médicament et l'échantillonnage d'analyte. Les pompes EC et les systèmes de l'invention sont configurés et construits de manière qu'ils soient de fabrication économique, compacts et précis.
PCT/US2005/013728 2004-04-21 2005-04-21 Systemes, dispositifs et procedes de relargage electrocinetique de medicament WO2005113419A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP05779953.8A EP1740497A4 (fr) 2004-04-21 2005-04-21 Systemes, dispositifs et procedes de relargage electrocinetique de medicament
CA2564800A CA2564800C (fr) 2004-04-21 2005-04-21 Systemes, dispositifs et procedes de relargage electrocinetique de medicament
CN2005800186796A CN101365885B (zh) 2004-04-21 2005-04-21 电动输送系统、装置和方法
AU2005245347A AU2005245347A1 (en) 2004-04-21 2005-04-21 Electrokinetic delivery systems, devices and methods
JP2007509658A JP4646976B2 (ja) 2004-04-21 2005-04-21 界面動電送達システム、装置及び方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56449704P 2004-04-21 2004-04-21
US60/564,497 2004-04-21

Publications (2)

Publication Number Publication Date
WO2005113419A2 WO2005113419A2 (fr) 2005-12-01
WO2005113419A3 true WO2005113419A3 (fr) 2007-12-27

Family

ID=35428903

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/013728 WO2005113419A2 (fr) 2004-04-21 2005-04-21 Systemes, dispositifs et procedes de relargage electrocinetique de medicament

Country Status (6)

Country Link
EP (1) EP1740497A4 (fr)
JP (1) JP4646976B2 (fr)
CN (1) CN101365885B (fr)
AU (1) AU2005245347A1 (fr)
CA (1) CA2564800C (fr)
WO (1) WO2005113419A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7887508B2 (en) * 2006-03-14 2011-02-15 The University Of Southern California MEMS device and method for delivery of therapeutic agents
WO2007125455A1 (fr) * 2006-04-28 2007-11-08 Koninklijke Philips Electronics N. V. Pompe osmotique comprenant au moins un matériau à charger
US8019404B2 (en) 2006-10-06 2011-09-13 The Cleveland Clinic Foundation Apparatus and method for targeting a body tissue
US8694077B2 (en) 2006-10-06 2014-04-08 The Cleveland Clinic Foundation Apparatus and method for targeting a body tissue
GB2448493B (en) * 2007-04-16 2009-10-14 Dewan Fazlul Hoque Chowdhury Microneedle transdermal delivery device
CA2834708A1 (fr) * 2011-05-05 2012-11-08 Eksigent Technologies, Llc Gel de couplage pour systemes de distribution de fluide electrocinetique
CA2834555A1 (fr) * 2011-05-05 2012-11-08 Eksigent Technologies, Llc Systeme et procede de commande de pression differentielle d'une pompe electrocinetique a mouvement alternatif
CN104487112A (zh) 2012-07-06 2015-04-01 赛诺菲-安万特德国有限公司 药物输送装置
CA2889149C (fr) 2012-10-22 2017-05-16 The Cleveland Clinic Foundation Appareil et procede de ciblage d'un tissu corporel
EP2957319A4 (fr) * 2013-02-18 2016-10-12 Terumo Corp Dispositif ainsi que système d'administration de médicament, et procédé de commande de ceux-ci
WO2015199981A1 (fr) * 2014-06-25 2015-12-30 Min Wei Dispositif de perfusion de médicament
US9416777B2 (en) 2014-09-26 2016-08-16 Becton, Dickinson And Company Control circuits for electrochemical pump with E-valves
US20160206811A1 (en) * 2014-12-30 2016-07-21 Jason Shih Implantable Electrolytic Diaphragm Pumps
KR101910932B1 (ko) * 2016-08-31 2018-10-23 이오플로우(주) 전기 삼투 펌프
KR101928297B1 (ko) 2016-09-08 2018-12-12 이오플로우(주) 약액 주입장치
JP6967797B2 (ja) * 2017-04-21 2021-11-17 ヨダカ技研株式会社 携帯用小型輸液装置
GB201714645D0 (en) 2017-09-12 2017-10-25 Osmotex Ag Method
US10809139B2 (en) * 2018-02-14 2020-10-20 Carefusion 303, Inc. Integrated sensor to monitor fluid delivery
JP6744527B1 (ja) * 2020-04-01 2020-08-19 アットドウス株式会社 薬液投与ユニット、薬液投与モジュール、薬液投与装置、及び投薬管理システム

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923426A (en) * 1974-08-15 1975-12-02 Alza Corp Electroosmotic pump and fluid dispenser including same
US4140122A (en) * 1976-06-11 1979-02-20 Siemens Aktiengesellschaft Implantable dosing device
US4886514A (en) * 1985-05-02 1989-12-12 Ivac Corporation Electrochemically driven drug dispenser
US6409698B1 (en) * 2000-11-27 2002-06-25 John N. Robinson Perforate electrodiffusion pump
US6495015B1 (en) * 1999-06-18 2002-12-17 Sandia National Corporation Electrokinetically pumped high pressure sprays
US20030232203A1 (en) * 2002-01-18 2003-12-18 The Regents Of The University Of Michigan Porous polymers: compositions and uses thereof
US6719535B2 (en) * 2002-01-31 2004-04-13 Eksigent Technologies, Llc Variable potential electrokinetic device

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2530220B2 (ja) * 1989-03-03 1996-09-04 日本特殊陶業株式会社 液体混合物分離装置
US5351164A (en) * 1991-10-29 1994-09-27 T.N. Frantsevich Institute For Problems In Materials Science Electrolytic double layer capacitor
WO1996039260A1 (fr) * 1995-06-06 1996-12-12 David Sarnoff Research Center, Inc. Procede de fabrication de conduits micro-electriques
US5961800A (en) * 1997-05-08 1999-10-05 Sarnoff Corporation Indirect electrode-based pumps
US6106685A (en) * 1997-05-13 2000-08-22 Sarnoff Corporation Electrode combinations for pumping fluids
US5942093A (en) * 1997-06-18 1999-08-24 Sandia Corporation Electro-osmotically driven liquid delivery method and apparatus
US6019882A (en) * 1997-06-25 2000-02-01 Sandia Corporation Electrokinetic high pressure hydraulic system
US6805783B2 (en) * 2000-12-13 2004-10-19 Toyo Technologies, Inc. Method for manipulating a solution using a ferroelectric electro-osmotic pump
US20030055380A1 (en) * 2001-09-19 2003-03-20 Flaherty J. Christopher Plunger for patient infusion device
WO2004036041A2 (fr) * 2002-10-18 2004-04-29 Eksigent Technologies, Llc Appareils electrocinetiques

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923426A (en) * 1974-08-15 1975-12-02 Alza Corp Electroosmotic pump and fluid dispenser including same
US4140122A (en) * 1976-06-11 1979-02-20 Siemens Aktiengesellschaft Implantable dosing device
US4886514A (en) * 1985-05-02 1989-12-12 Ivac Corporation Electrochemically driven drug dispenser
US6495015B1 (en) * 1999-06-18 2002-12-17 Sandia National Corporation Electrokinetically pumped high pressure sprays
US6409698B1 (en) * 2000-11-27 2002-06-25 John N. Robinson Perforate electrodiffusion pump
US20030232203A1 (en) * 2002-01-18 2003-12-18 The Regents Of The University Of Michigan Porous polymers: compositions and uses thereof
US6719535B2 (en) * 2002-01-31 2004-04-13 Eksigent Technologies, Llc Variable potential electrokinetic device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1740497A4 *

Also Published As

Publication number Publication date
AU2005245347A1 (en) 2005-12-01
JP2008504794A (ja) 2008-02-14
CA2564800C (fr) 2014-04-15
CN101365885B (zh) 2011-08-03
CN101365885A (zh) 2009-02-11
JP4646976B2 (ja) 2011-03-09
EP1740497A4 (fr) 2015-11-11
CA2564800A1 (fr) 2005-12-01
WO2005113419A2 (fr) 2005-12-01
EP1740497A2 (fr) 2007-01-10

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