WO2005099713A3 - Nueva presentación de una composición farmacéutica antiviral - Google Patents

Nueva presentación de una composición farmacéutica antiviral Download PDF

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Publication number
WO2005099713A3
WO2005099713A3 PCT/MX2004/000025 MX2004000025W WO2005099713A3 WO 2005099713 A3 WO2005099713 A3 WO 2005099713A3 MX 2004000025 W MX2004000025 W MX 2004000025W WO 2005099713 A3 WO2005099713 A3 WO 2005099713A3
Authority
WO
WIPO (PCT)
Prior art keywords
around
amount
pharmaceutical composition
novel antiviral
antiviral pharmaceutical
Prior art date
Application number
PCT/MX2004/000025
Other languages
English (en)
French (fr)
Other versions
WO2005099713A2 (es
Inventor
Flores Francisco Barreiro
Original Assignee
Liomont S A De C V Lab
Flores Francisco Barreiro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liomont S A De C V Lab, Flores Francisco Barreiro filed Critical Liomont S A De C V Lab
Priority to DE602004014202T priority Critical patent/DE602004014202D1/de
Priority to AT04725836T priority patent/ATE396732T1/de
Priority to US11/547,275 priority patent/US8697712B2/en
Priority to ES04725836T priority patent/ES2308170T3/es
Priority to CA2562190A priority patent/CA2562190C/en
Priority to EP04725836A priority patent/EP1741425B1/en
Priority to PCT/MX2004/000025 priority patent/WO2005099713A2/es
Publication of WO2005099713A2 publication Critical patent/WO2005099713A2/es
Publication of WO2005099713A3 publication Critical patent/WO2005099713A3/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/121Solutions, i.e. homogeneous liquid formulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Nueva presentación de una composición farmacéutica antiviral en solución, que comprende como principio activo el aciclovir en una cantidad de aproximadamente el 5% en peso; un solvente en una cantidad de aproximadamente del 10 al 20% en peso; un agente solubilizante en una cantidad de aproximadamente 1.5 al 5.0% en peso; un agente humectante en una cantidad de aproximadamente del 2 al 10% en peso; un agente antiprurítico en una cantidad de aproximadamente 0.05 al 1.0% en peso; un agente antioxidante en una cantidad de alrededor del 0.1 al 0.5% en peso; y; agua desmineralizada en una cantidad de alrededor del 20 al 80% en peso.
PCT/MX2004/000025 2004-04-05 2004-04-05 Nueva presentación de una composición farmacéutica antiviral WO2005099713A2 (es)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE602004014202T DE602004014202D1 (de) 2004-04-05 2004-04-05 Neue antivirale pharmazeutische zusammensetzung
AT04725836T ATE396732T1 (de) 2004-04-05 2004-04-05 Neue antivirale pharmazeutische zusammensetzung
US11/547,275 US8697712B2 (en) 2004-04-05 2004-04-05 Presentation of an antiviral pharmaceutical composition
ES04725836T ES2308170T3 (es) 2004-04-05 2004-04-05 Nueva composicion farmaceutica antiviral.
CA2562190A CA2562190C (en) 2004-04-05 2004-04-05 Novel antiviral pharmaceutical composition
EP04725836A EP1741425B1 (en) 2004-04-05 2004-04-05 Novel antiviral pharmaceutical composition
PCT/MX2004/000025 WO2005099713A2 (es) 2004-04-05 2004-04-05 Nueva presentación de una composición farmacéutica antiviral

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/MX2004/000025 WO2005099713A2 (es) 2004-04-05 2004-04-05 Nueva presentación de una composición farmacéutica antiviral

Publications (2)

Publication Number Publication Date
WO2005099713A2 WO2005099713A2 (es) 2005-10-27
WO2005099713A3 true WO2005099713A3 (es) 2005-12-08

Family

ID=35150496

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/MX2004/000025 WO2005099713A2 (es) 2004-04-05 2004-04-05 Nueva presentación de una composición farmacéutica antiviral

Country Status (7)

Country Link
US (1) US8697712B2 (es)
EP (1) EP1741425B1 (es)
AT (1) ATE396732T1 (es)
CA (1) CA2562190C (es)
DE (1) DE602004014202D1 (es)
ES (1) ES2308170T3 (es)
WO (1) WO2005099713A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201819418D0 (en) 2018-11-29 2019-01-16 Daniel Calladine Ltd Anti-viral compositions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6379692B1 (en) * 1997-09-03 2002-04-30 Chauvin Pharmaceuticals Limited Pharmaceutical composition comprising a suspension for the active ingredient

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2080106B (en) * 1980-07-18 1984-03-07 Weelcome Foundation Ltd Acyclovin preparations
US5331012A (en) * 1990-07-30 1994-07-19 Riddick Kenneth B Topical pharmaceutical preparation for fever blisters and other viral infections and method of use
IL104283A (en) * 1992-12-30 1996-12-05 Agis Ind 1983 Ltd Non-emulsion antiviral topical pharmaceutical composition comprising acyclovir an aqueous gel agent and an alkali oleate
AUPP583198A0 (en) * 1998-09-11 1998-10-01 Soltec Research Pty Ltd Mousse composition
FR2837102B1 (fr) * 2002-03-18 2004-10-08 Palbian Snc Composition a l'etat de gel aqueux, procede de fabrication et utilisation pour la fabrication d'un medicament, notamment antiherpetique
US20050031655A1 (en) * 2003-08-04 2005-02-10 Schering Plough Healthcare Products, Inc. Emulsion composition

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6379692B1 (en) * 1997-09-03 2002-04-30 Chauvin Pharmaceuticals Limited Pharmaceutical composition comprising a suspension for the active ingredient

Also Published As

Publication number Publication date
EP1741425A4 (en) 2007-07-11
US20080287470A1 (en) 2008-11-20
DE602004014202D1 (de) 2008-07-10
CA2562190C (en) 2012-08-21
WO2005099713A2 (es) 2005-10-27
ES2308170T3 (es) 2008-12-01
US8697712B2 (en) 2014-04-15
EP1741425A2 (en) 2007-01-10
CA2562190A1 (en) 2005-10-27
ATE396732T1 (de) 2008-06-15
EP1741425B1 (en) 2008-05-28

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