WO2005094769A1 - Cosmetic or dermatological preparations containing a mixture of a uv-a filter, a uv-b filter, and a metal oxide - Google Patents

Cosmetic or dermatological preparations containing a mixture of a uv-a filter, a uv-b filter, and a metal oxide Download PDF

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Publication number
WO2005094769A1
WO2005094769A1 PCT/EP2005/001499 EP2005001499W WO2005094769A1 WO 2005094769 A1 WO2005094769 A1 WO 2005094769A1 EP 2005001499 W EP2005001499 W EP 2005001499W WO 2005094769 A1 WO2005094769 A1 WO 2005094769A1
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Prior art keywords
cosmetic
weight
dermatological preparations
filter
uvinul
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PCT/EP2005/001499
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German (de)
French (fr)
Inventor
Valerie Andre
Thomas Wünsch
Michael Schaper
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Basf Aktiengesellschaft
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/29—Titanium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A61K8/411—Aromatic amines, i.e. where the amino group is directly linked to the aromatic nucleus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4966—Triazines or their condensed derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Definitions

  • Cosmetic or dermatological preparations containing a mixture of a UV-A filter, a UV-B filter and a metal oxide.
  • the invention relates to cosmetic or dermatological preparations containing a mixture of a UV-A filter, a UV-B filter and a metal oxide.
  • the light stabilizers used in cosmetic and dermatological preparations have the task of preventing harmful effects of sunlight on human skin or at least reducing their effects. In addition, these light stabilizers also serve to protect other ingredients from destruction or degradation by UV radiation. In hair cosmetic formulations, damage to the keratin fiber by UV rays is to be reduced.
  • UV-B 280 to 320 ⁇ m
  • UV-A radiation > 320 nm
  • the influence on human skin is particularly noticeable with UV-B radiation due to sunburn. Accordingly, the industry offers a larger number of substances that absorb UV-B radiation and thus prevent sunburn.
  • UV-B filter is 2, 4, 6-trianilino-p- (carbo-2 '-ethyl-hexyl-1 x -oxi) -1, 3, 5-triazine, which is from BASF Aktiengesellschaft under the trade name Uvmul T150 is being marketed.
  • Uvinul ® T150 is characterized by good UV absorption properties with an exceptionally high extinction coefficient> 1500 at 314 nm.
  • N, N-Diethylamino-hydroxybenzoyl-n-hexylbenzoate of the formula II is a UV-A filter which is marketed by BASF Aktiengesellschaft under the trade name Uvinul A Plus.
  • the metal oxides zinc oxide and / or titanium dioxide used as component c) are preferably used as micropigments with a primary particle size of 5 to 200 nm, particularly preferably 10 to 60 nm. It may also be advantageous if the metalloxides are in hydrophobicized form, i.e. that they are treated to be water-repellent on the surface. Examples of surface-treated pigments include in DE-A-33 14 742, EP-A-0 518 772 and in EP-A-0 518 773.
  • Examples of commercially available zinc oxide or titanium dioxide are Uvinul ® Ti0 2 and Z-Cote ® , both of which are marketed by BASF Aktiengesellschaft.
  • Cosmetic or dermatological preparations containing are preferred
  • Cosmetic or dermatological preparations containing are particularly preferred
  • the cosmetic and dermatological preparations containing light stabilizers are generally based on a carrier which contains at least one oil phase. Accordingly, oils, oil-in-water and water-in-oil emulsions, creams and pastes, lip protection stick compositions or grease-free gels are suitable.
  • sun protection preparations of this type can be in liquid, pasty or solid form, for example as water-in-oil creams, oil-in-water creams and lotions, aerosol foam creams, gels, oils, grease pencils, powders, sprays or alcoholic water lotions.
  • Customary oil components in cosmetics are, for example, paraffin oil, glyceryl stearate, isopropyl yristate, diisopropyl adipate, 2-ethylhexanoic acid cetyl stearyl ester, hydrogenated polyisobutene, petroleum jelly, caprylic acid / capric acid triglycerides, microcrystalline wax, lanolin and stearic acid and silicone oil.
  • Suitable silicone oils are e.g. linear polydimethylsiloxanes, poly (methylphenylsiloxanes), cyclic siloxanes and mixtures thereof.
  • the number average molecular weight of the polydimethylsiloxanes and poly (methylphenylsiloxanes) is preferably in a range from about 1000 to 150,000 g / mol.
  • Preferred cyclic siloxanes have 4- to 8-membered rings.
  • Suitable cyclic siloxanes are e.g. commercially available under the name cyclomethicone.
  • Typical cosmetic auxiliaries which can be considered as additives are, for example, co-emulsifiers, fats and waxes, stabilizers, thickeners, biogenic active substances, film formers, fragrances, dyes, pearlescent agents, preservatives, pigments, electrolytes (for example magnesium sulfate) and pH -Regulatoren.
  • co-emulsifiers for example, co-emulsifiers, fats and waxes, stabilizers, thickeners, biogenic active substances, film formers, fragrances, dyes, pearlescent agents, preservatives, pigments, electrolytes (for example magnesium sulfate) and pH -Regulatoren.
  • Known W / O and, in addition, O / W emulsifiers such as polyglycerol esters, sorbitan esters or partially esterified glycerides are preferred as co-emulsifiers.
  • Typical examples of fats are glycerides; as waxes include beeswax, paraffin wax or microwaxes, optionally in combination with hydrophilic waxes.
  • Metal salts of fatty acids such as magnesium, aluminum and / or zinc stearate can be used as stabilizers.
  • Suitable thickeners are, for example, crosslinked polyacrylic acids and their derivatives, polysaccharides, in particular xanthan gum, guar guar, agar agar, alginates and tyloses, carboxymethyl cellulose and hydroxyethyl cellulose, furthermore fatty alcohols, monoglycerides and fatty acids, polyacrylates, Polyvinyl alcohol and polyvinyl pyrrolidone.
  • Biogenic active ingredients are understood to mean, for example, plant extracts, protein hydrolyzates and vitamin complexes.
  • Common film Formers are, for example, hydrocolloids such as chitosan, microcrystalline chitosan or quaternized chitosan, polyvinylpyrrolidone, vinylpyrrolidone-vinyl acetate copolymers, polymers of the acrylic acid series, quaternary cellulose derivatives and similar compounds.
  • Suitable preservatives are, for example, formaldehyde solution, parabens such as methyl paraben, 1, 2-dibromo-2, 4-di-cyanobutane, p-hydroxybenzoate or sorbic acid.
  • Suitable pearlizing agents are, for example, glycol distearic acid esters such as ethylene glycol distearate, but also fatty acids and fatty acid monoglycol esters.
  • the dyes which can be used are the substances which are suitable and approved for cosmetic purposes, as compiled, for example, in the publication "Cosmetic Dyes” by the Dye Commission of the German Research Foundation, published by Verlag Chemie, Weinheim, 1984. These dyes are usually used in a concentration of 0.001 to 1% by weight, based on the mixture as a whole.
  • the total proportion of auxiliaries and additives can be 1 to 80, preferably 6 to 40% by weight and the non-aqueous proportion ("active substance") 20 to 80, preferably 30 to 70% by weight, based on the composition. be.
  • the preparation of the agents can be carried out in a manner known per se, i.e. for example by hot, cold, hot / cold or PIT emulsification. This is a purely mechanical process, there is no chemical reaction.
  • UV filter substances Any UV-A and UV-B filter substances are suitable as UV filter substances which can be used with the combination of Uvinul T150, Uvinul A Plus together with zinc oxide and / or titanium dioxide. Examples include:
  • the light protection preparations according to the invention can be used as shampoos, lotions, gels, hair sprays, aerosol foam creams or emulsions, inter alia, for washing, dyeing and styling the hair.
  • UV filter action of the preparations according to the invention can also be used to stabilize active ingredients and auxiliaries in cosmetic and dermatological formulations.
  • the preparations according to the invention are distinguished by a particularly high absorption capacity in the area of UV-B radiation with a sharp band structure and high sun protection factors.
  • the high sun protection factor of the preparations which was measured even at low concentrations of UV-absorbing active ingredients, was surprising.
  • the sun protection factor of the cosmetic or dermatological formulations is in the range greater than 14, preferably in the range greater than 25.
  • Corresponding values can be achieved, for example, by means of a light protection emulsion with a Uvinul T150 content of 3% by weight, Uvinul® A Plus of 2% by weight. % and a concentration of zinc oxide and / or titanium dioxide of 4% by weight.
  • Uvinul T 150 0.1 to 10% by weight, preferably 1 to 6% by weight, particularly preferably 2 to 6% by weight , very particularly preferably 2 to 4 wt .-%), Uvinul A Plus ® (0.1 to 10 wt .-%, preferably 1 to 6 wt .-%, particularly preferably 1 to 5 wt .-%, most preferably 1 to 3% by weight) and zinc oxide or titanium dioxide (0.1 to 15% by weight, preferably 1 to 8% by weight, particularly preferably 2 to 6% by weight) already satisfactory sun protection values can be obtained.
  • Uvinul T 150 0.1 to 10% by weight, preferably 1 to 6% by weight, particularly preferably 2 to 6% by weight , very particularly preferably 2 to 4 wt .-%)
  • Uvinul A Plus ® 0.1 to 10 wt .-%, preferably 1 to 6 wt .-%, particularly preferably 1 to 5 wt .-%, most preferably 1 to 3% by weight
  • phase A and C were heated separately to approx. 85 ° C.
  • Phase C and the metal oxide were then stirred into phase A with homogenization.
  • the emulsion was cooled to room temperature with stirring and bottled. All quantities are based on the total weight of the preparations.
  • Emulsion A containing 3% by weight Uvinul ® T150, 2% by weight Uvinul ® A Plus and 4% by weight zinc oxide (sun protection factor 29)
  • Emulsion B containing 3% by weight Uvinul ® T150 and 2% by weight Uvinul 0 A Plus (sun protection factor 17)
  • Emulsion C containing 3% by weight of Uvinul ® T150 and 4% by weight of zinc oxide (sun protection factor 23)
  • Emulsion D containing 3% by weight of Uvinul ® T150 and 4% by weight of Uvinul ® Ti0 2 (sun protection factor 23)
  • Emulsion E containing 3% by weight Uvinul ® T150 (sun protection factor 9)
  • Emulsion F containing 4% by weight zinc oxide (sun protection factor 4)
  • Emulsion G containing 4% by weight Uvinul ® Ti0 (sun protection factor 6)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
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Abstract

Disclosed are cosmetic or dermatological preparations containing a) 0.1 to 10 wt. % of 2,4,6-trianilino-p-(carbo-2`-ethyl-hexyl-1`-oxi)-1,3,5-triazine of formula (I), b) 0.1 to 10 wt. % of N,N-diethylamino-hydroxybenzoyl-n-hexyl benzoate of formula (II), and c) 0.1 to 15 wt. % of zinc oxide and/or titanium dioxide.

Description

Kosmetische oder dermatologische Zubereitungen, enthaltend ein Gemisch aus einem UV-A-Filter, einem UV-B-Filter und einem Metalloxid. Cosmetic or dermatological preparations containing a mixture of a UV-A filter, a UV-B filter and a metal oxide.
Beschreibungdescription
Die Erfindung betrifft kosmetische oder dermatologische Zubereitungen, enthaltend ein Gemisch aus einem UV-A-Filter, einem UV-B- Filter und einem Metalloxid.The invention relates to cosmetic or dermatological preparations containing a mixture of a UV-A filter, a UV-B filter and a metal oxide.
Die in kosmetischen und dermatologischen Zubereitungen eingesetzten Lichtschutzmittel haben die Aufgabe, schädigende Einflüsse des Sonnenlichts auf die menschliche Haut zu verhindern oder zu- mindest in ihren Auswirkungen zu reduzieren. Daneben dienen diese Lichtschutzmittel aber auch dem Schutz weiterer Inhaltsstoffe vor Zerstörung oder Abbau durch UV-Strahlung. In haarkosmetischen Formulierungen soll eine Schädigung der Keratinfaser durch UV- Strahlen vermindert werden.The light stabilizers used in cosmetic and dermatological preparations have the task of preventing harmful effects of sunlight on human skin or at least reducing their effects. In addition, these light stabilizers also serve to protect other ingredients from destruction or degradation by UV radiation. In hair cosmetic formulations, damage to the keratin fiber by UV rays is to be reduced.
Das an die Erdoberfläche gelangende Sonnenlicht hat einen Anteil an UV-B- (280 bis 320 um) und an UV-A-Strahlung (> 320 nm) , welche sich direkt an den Bereich des sichtbaren Lichtes anschließen. Der Einfluß auf die menschliche Haut macht sich besonders bei der UV-B-Strahlung durch Sonnenbrand bemerkbar. Dementsprechend bietet die Industrie eine größere Zahl von Substanzen an, welche die UV-B-Strahlung absorbieren und damit den Sonnenbrand verhindern.The sunlight reaching the earth's surface has a proportion of UV-B (280 to 320 µm) and UV-A radiation (> 320 nm), which directly adjoin the range of visible light. The influence on human skin is particularly noticeable with UV-B radiation due to sunburn. Accordingly, the industry offers a larger number of substances that absorb UV-B radiation and thus prevent sunburn.
Ein vorteilhafter UV-B-Filter ist 2 , 4 , 6-Trianilino- p- (carbo-2 ' -ethyl-hexyl-1 x-oxi) -1 , 3 , 5-triazin, der von der BASF Aktiengesellschaft unter der Warenbezeichnung Uvmul T150 vermarktet wird.An advantageous UV-B filter is 2, 4, 6-trianilino-p- (carbo-2 '-ethyl-hexyl-1 x -oxi) -1, 3, 5-triazine, which is from BASF Aktiengesellschaft under the trade name Uvmul T150 is being marketed.
4H9
Figure imgf000003_0001
Uvinul® T150 zeichnet sich durch gute UV-Absorptionseigenschaften mit einem außergewöhnlich hohen Extinktionskoeffizienten > 1500 bei 314 nm aus . Ein Nachteil dieses UV-B-Filters ist jedoch die für viele kosmetische Anwendungen unzureichende Löslichkeit in kosmetischen Ölen. 4 H 9
Figure imgf000003_0001
Uvinul ® T150 is characterized by good UV absorption properties with an exceptionally high extinction coefficient> 1500 at 314 nm. A disadvantage of this UV-B filter, however, is the insufficient solubility in cosmetic oils for many cosmetic applications.
Aufgrund der nur gering zu erzielenden Einsatzkonzentrationen an Uvinul® T150 ist die Verwendung dieses UV-B-Filters für die Herstellung von kosmetischen oder dermatologischen Lichtschutzzubereitungen mit hohen Sonnenschutzfaktoren (SPF > 15) häufig eingeschränkt . Zahlreiche Patentanmeldungen bzw. Patentschriften, u.a. US 5,489,431, DE-A-197 03 471, DE-A-196 32 913, DE-A-196 02 619, DE-A-196 35 057, DE-A-196 33 012, EP-A-0 685 223 beschreiben die Verwendung von Lösungsvermittlern, lipophilen Lösungsmitteln oder speziellen Kombinationen mit anderen UV-Absorbern zur Verbesse- rung der Löslichkeit von Uvinul® T150.Due to the low concentrations of Uvinul ® T150 that can be achieved, the use of this UV-B filter for the manufacture of cosmetic or dermatological sunscreen preparations with high sun protection factors (SPF> 15) is often restricted. Numerous patent applications and patents, including US 5,489,431, DE-A-197 03 471, DE-A-196 32 913, DE-A-196 02 619, DE-A-196 35 057, DE-A-196 33 012, EP-A-0685223 describe the use of solubilizers, lipophilic solvents or specific combinations with other UV absorbers for improving the solubility of Uvinul ® T150.
Es bestand nun die Aufgabe, kosmetische oder dermatologische Lichtschutzzubereitungen bereitzustellen, die bei nur geringen Konzentrationen an UV-Absorbern, möglichst hohe Lichtschutzfakto- ren aufweisen.The task now was to provide cosmetic or dermatological light protection preparations which, with only low concentrations of UV absorbers, have the highest possible light protection factors.
Diese Aufgabe wurde erfindungsgemäß gelöst durch kosmetische oder dermatologische Zubereitungen, enthaltendThis object was achieved according to the invention by cosmetic or dermatological preparations containing
a) 0,1 bis 10 Gew.-% 2, 4, 6-Trianilino-p- (carbo-2 λ -ethyl-he- xγl-1 v-oxi) -1, 3 , 5-triazin der Formel Ia) 0.1 to 10 wt .-% 2, 4, 6-trianilino-p- (carbo-2 λ- ethyl-he-xγl-1 v -oxi) -1, 3, 5-triazine of the formula I.
4H9
Figure imgf000004_0001
 4 H 9
Figure imgf000004_0001
b) 0,1 bis 10 Gew.-% N,N-Diethylamino-hydroxybenzoyl-n-hexylben- zoat der Formel II
Figure imgf000005_0001
und c) 0,1 bis 15 Gew.-% Zinkoxid und/oder Titandioxid.b) 0.1 to 10% by weight of N, N-diethylamino-hydroxybenzoyl-n-hexylbenzoate of the formula II
Figure imgf000005_0001
and c) 0.1 to 15% by weight of zinc oxide and / or titanium dioxide.
N,N-Diethylamino-hydroxybenzoyl-n-hexylbenzoat der Formel II ist ein UV-A-Filter, der von der BASF Aktiengesellschaft unter der Warenbezeichnung Uvinul A Plus vermarktet wird.N, N-Diethylamino-hydroxybenzoyl-n-hexylbenzoate of the formula II is a UV-A filter which is marketed by BASF Aktiengesellschaft under the trade name Uvinul A Plus.
Die als Komponente c) verwendeten Metalloxide Zinkoxid und/oder Titandioxid werden bevorzugt als Mikropigmente mit einer Primärteilchengröße von 5 bis 200 nm, besonders bevorzugt 10 bis 60 nm eingesetzt. Außerdem kann es von Vorteil sein, wenn die Metallo- xide in hydrophobierter Form vorliegen, d.h. daß sie oberflächlich wasserabweisend behandelt sind. Beispiele für oberflächenbehandelte Pigmente finden sich u.a. in DE-A-33 14 742, EP-A-0 518 772 sowie in EP-A-0 518 773.The metal oxides zinc oxide and / or titanium dioxide used as component c) are preferably used as micropigments with a primary particle size of 5 to 200 nm, particularly preferably 10 to 60 nm. It may also be advantageous if the metalloxides are in hydrophobicized form, i.e. that they are treated to be water-repellent on the surface. Examples of surface-treated pigments include in DE-A-33 14 742, EP-A-0 518 772 and in EP-A-0 518 773.
Beispiele für kommerziell erhältliches Zinkoxid oder Titandioxid sind Uvinul® Ti02 und Z-Cote®, die beide von der BASF Aktiengesellschaft vermarktet werden.Examples of commercially available zinc oxide or titanium dioxide are Uvinul ® Ti0 2 and Z-Cote ® , both of which are marketed by BASF Aktiengesellschaft.
Bevorzugt sind kosmetische oder dermatologische Zubereitungen, enthaltendCosmetic or dermatological preparations containing are preferred
a) 1 bis 6 Gew.-% der Verbindung I,a) 1 to 6% by weight of compound I,
b) 1 bis 6 Gew.-% der Verbindung II undb) 1 to 6 wt .-% of compound II and
c) 1 bis 8 Gew.-% Zinkoxid und/oder Titandioxid.c) 1 to 8 wt .-% zinc oxide and / or titanium dioxide.
Besonders bevorzugt sind kosmetische oder dermatologische Zubereitungen, enthaltendCosmetic or dermatological preparations containing are particularly preferred
a) 2 bis 6 Gew.-% der Verbindung I,a) 2 to 6% by weight of compound I,
b) 1 bis 5 Gew.-% der Verbindung II undb) 1 to 5 wt .-% of compound II and
c) 2 bis 6 Gew.-% Zinkoxid. Die Lichtschutzmittel enthaltenden kosmetischen und dermatologischen Zubereitungen sind in der Regel auf der Basis eines Trägers, der mindestens eine Ölphase enthält. Demgemäß kommen Öle, Öl-in-Wasser- und Wasser-in-Öl-Emulsionen, Cremes und Pasten, Lippenschutzstiftmassen oder fettfreie Gele in Betracht.c) 2 to 6 wt .-% zinc oxide. The cosmetic and dermatological preparations containing light stabilizers are generally based on a carrier which contains at least one oil phase. Accordingly, oils, oil-in-water and water-in-oil emulsions, creams and pastes, lip protection stick compositions or grease-free gels are suitable.
Solche Sonnenschutzpräparate können demgemäß in flüssiger, paεtö- ser oder fester Form vorliegen, beispielsweise als Wasser-in-Öl- Cremes, Öl-in-Wasser-Cremes und -Lotionen, Aerosol-Schaumcremes, Gele, Öle, Fettstifte, Puder, Sprays oder alkoholisch-wäßrige Lotionen.Accordingly, sun protection preparations of this type can be in liquid, pasty or solid form, for example as water-in-oil creams, oil-in-water creams and lotions, aerosol foam creams, gels, oils, grease pencils, powders, sprays or alcoholic water lotions.
Übliche Ölkomponenten in der Kosmetik sind beispielsweise Paraf- finöl, Glycerylstearat , Isopropyl yristat, Diisopropyladipat, 2-Ethylhexansäurecetylstearylester, hydriertes Polyisobuten, Vaseline, Caprylsäure/Caprinsäure-Triglyceride, mikrokristallines Wachs, Lanolin und Stearinsäure sowie Siliconöle.Customary oil components in cosmetics are, for example, paraffin oil, glyceryl stearate, isopropyl yristate, diisopropyl adipate, 2-ethylhexanoic acid cetyl stearyl ester, hydrogenated polyisobutene, petroleum jelly, caprylic acid / capric acid triglycerides, microcrystalline wax, lanolin and stearic acid and silicone oil.
Geeignete Siliconöle sind z.B. lineare Polydimethylsiloxane, Poly (methylphenylsiloxane) , cyclische Siloxane und Mischungen davon. Das zahlenmittlere Molekulargewicht der Polydimethylsiloxane und Poly (methylphenylsiloxane) liegt vorzugsweise in einem Bereich von etwa 1000 bis 150000 g/mol. Bevorzugte cyclische Siloxane weisen 4- bis 8-gliedrige Ringe auf. Geeignete cyclische Si- loxane sind z.B. unter der Bezeichnung Cyclomethicon kommerziell erhältlich.Suitable silicone oils are e.g. linear polydimethylsiloxanes, poly (methylphenylsiloxanes), cyclic siloxanes and mixtures thereof. The number average molecular weight of the polydimethylsiloxanes and poly (methylphenylsiloxanes) is preferably in a range from about 1000 to 150,000 g / mol. Preferred cyclic siloxanes have 4- to 8-membered rings. Suitable cyclic siloxanes are e.g. commercially available under the name cyclomethicone.
Übliche kosmetische Hilfsstoffe, die als Zusätze in Betracht kommen können, sind z.B. Co-Emulgatoren, Fette und Wachse, Stabili- satoren, Verdickungsmittel , biogene Wirkstoffe, Filmbildner, Duftstoffe, Farbstoffe, Perlglanzmittel, Konservierungsmittel, Pigmente, Elektrolyte (z.B. Magnesiumsulfat) und pH-Regulatoren. Als Co-Emulgatoren kommen vorzugsweise bekannte W/0- und daneben auch O/W-Emulgatoren wie etwa Polyglycerinester, Sorbitanester oder teilveresterte Glyceride in Betracht. Typische Beispiele für Fette sind Glyceride; als Wachse sind u.a. Bienenwachs, Paraffinwachs oder Mikrowachse gegebenenfalls in Kombination mit hydrophilen Wachsen zu nennen. Als Stabilisatoren können Metallsalze von Fettsäuren wie z.B. Magnesium-, Aluminium- und/oder Zinkstea- rat eingesetzt werden. Geeignete Verdickungsmittel sind beispielsweise vernetzte Polyacrylsäuren und deren Derivate, Poly- saccharide, insbesondere Xanthan-Gum, Guar-Guar, Agar-Agar, Algi- nate und Tylosen, Carboxymethylcellulose und Hydroxyethylcellu- lose, ferner Fettalkohole, Monoglyceride und Fettsäuren, Poly- acrylate, Polyvinylalkohol und Polyvinylpyrrolidon. Unter bioge- nen Wirkstoffen sind beispielsweise Pflanzenextrakte, Eiweißhy- drolysate und Vitaminkomplexe zu verstehen. Gebräuchliche Film- bildner sind beispielsweise Hydrocolloide wie Chitosan, mikrokristallines Chitosan oder quaterniertes Chitosan, Polyvinylpyrroli- don, Vinylpyrrolidon-Vinylacetat-Copoly erisate, Polymere der Acrylsäurereihe, quaternäre Cellulose-Derivate und ähnliche Ver- bindungen. Als Konservierungsmittel eignen sich beispielsweise Formaldehydlösung, Parabene wie Methylparaben, 1, 2-Dibrom-2 , 4-di- cyanobutan, p-Hydroxybenzoat oder Sorbinsäure. Als Perlglanzmittel kommen beispielsweise Glycoldistearinsäureester wie Ethylen- glycoldistearat, aber auch Fettsäuren und Fettsäuremonoglycole- ster in Betracht. Als Farbstoffe können die für kosmetische Zwecke geeigneten und zugelassenen Substanzen verwendet werden, wie sie beispielsweise in der Publikation "Kosmetische Färbemittel" der Farbstoffkommission der Deutschen Forschungsgemeinschaft, veröffentlicht im Verlag Chemie, Weinheim, 1984, zusam- mengestellt sind. Diese Farbstoffe werden üblicherweise in Konzentration von 0,001 bis 1 Gew.-%, bezogen auf die gesamte Mischung, eingesetzt.Typical cosmetic auxiliaries which can be considered as additives are, for example, co-emulsifiers, fats and waxes, stabilizers, thickeners, biogenic active substances, film formers, fragrances, dyes, pearlescent agents, preservatives, pigments, electrolytes (for example magnesium sulfate) and pH -Regulatoren. Known W / O and, in addition, O / W emulsifiers such as polyglycerol esters, sorbitan esters or partially esterified glycerides are preferred as co-emulsifiers. Typical examples of fats are glycerides; as waxes include beeswax, paraffin wax or microwaxes, optionally in combination with hydrophilic waxes. Metal salts of fatty acids such as magnesium, aluminum and / or zinc stearate can be used as stabilizers. Suitable thickeners are, for example, crosslinked polyacrylic acids and their derivatives, polysaccharides, in particular xanthan gum, guar guar, agar agar, alginates and tyloses, carboxymethyl cellulose and hydroxyethyl cellulose, furthermore fatty alcohols, monoglycerides and fatty acids, polyacrylates, Polyvinyl alcohol and polyvinyl pyrrolidone. Biogenic active ingredients are understood to mean, for example, plant extracts, protein hydrolyzates and vitamin complexes. Common film Formers are, for example, hydrocolloids such as chitosan, microcrystalline chitosan or quaternized chitosan, polyvinylpyrrolidone, vinylpyrrolidone-vinyl acetate copolymers, polymers of the acrylic acid series, quaternary cellulose derivatives and similar compounds. Suitable preservatives are, for example, formaldehyde solution, parabens such as methyl paraben, 1, 2-dibromo-2, 4-di-cyanobutane, p-hydroxybenzoate or sorbic acid. Suitable pearlizing agents are, for example, glycol distearic acid esters such as ethylene glycol distearate, but also fatty acids and fatty acid monoglycol esters. The dyes which can be used are the substances which are suitable and approved for cosmetic purposes, as compiled, for example, in the publication "Cosmetic Dyes" by the Dye Commission of the German Research Foundation, published by Verlag Chemie, Weinheim, 1984. These dyes are usually used in a concentration of 0.001 to 1% by weight, based on the mixture as a whole.
Der Gesamtanteil der Hilfs- und Zusatzstoffe kann 1 bis 80, vor- zugsweise 6 bis 40 Gew.-% und der nicht wäßrige Anteil ("Aktivsubstanz") 20 bis 80, vorzugsweise 30 bis 70 Gew.-% - bezogen auf die Mittel - betragen. Die Herstellung der Mittel kann in an sich bekannter Weise, d.h. beispielsweise durch Heiß-, Kalt-, Heiß/ Kalt- bzw. PIT-Emulgierung erfolgen. Hierbei handelt es sich um ein rein mechanisches Verfahren, eine chemische Reaktion findet nicht statt.The total proportion of auxiliaries and additives can be 1 to 80, preferably 6 to 40% by weight and the non-aqueous proportion ("active substance") 20 to 80, preferably 30 to 70% by weight, based on the composition. be. The preparation of the agents can be carried out in a manner known per se, i.e. for example by hot, cold, hot / cold or PIT emulsification. This is a purely mechanical process, there is no chemical reaction.
Schließlich können weitere an sich bekannte im UV-Bereich absorbierenden Substanzen mitverwendet werden, sofern sie im Gesamtsy- stem der erfindungsgemäß zu verwendenden Kombination aus UV-Filtern stabil sind.Finally, other substances which are known per se in the UV range can also be used, provided they are stable in the overall system of the combination of UV filters to be used according to the invention.
Als UV-Filtersubstanzen, die mit der erfindungsgemäßen Kombination aus Uvinul T150, Uvinul A Plus zusammen mit Zinkoxid und/ oder Titandioxid angewandt werden können, kommen beliebige UV-A- und UV-B-Filtersubstanzen in Betracht. Beispielsweise sind zu nennen:Any UV-A and UV-B filter substances are suitable as UV filter substances which can be used with the combination of Uvinul T150, Uvinul A Plus together with zinc oxide and / or titanium dioxide. Examples include:
Tabelle 1:Table 1:
Figure imgf000007_0001
Figure imgf000008_0001
Figure imgf000009_0001
Zum Schutz menschlicher Haare vor UV-Strahlen können die erfindungsgemäßen Lichtschutzzubereitungen als Shampoos, Lotionen, Gelen, Haarsprays, Aerosol-Schaumcremes oder Emulsionen u.a. zum Waschen, Färben sowie zum Frisieren der Haare verwendet werdenverwendet werden.
Figure imgf000007_0001
Figure imgf000008_0001
Figure imgf000009_0001
To protect human hair from UV rays, the light protection preparations according to the invention can be used as shampoos, lotions, gels, hair sprays, aerosol foam creams or emulsions, inter alia, for washing, dyeing and styling the hair.
Die UV-Filterwirkung der erfindungsgemäßen Zubereitungen kann auch zur Stabilisierung von Wirk- und Hilfsstoffen in kosmetischen und dermatologischen Formulierungen ausgenutzt werden.The UV filter action of the preparations according to the invention can also be used to stabilize active ingredients and auxiliaries in cosmetic and dermatological formulations.
Die erfindungsgemäßen Zubereitungen zeichnen sich durch ein besonders hohes Absorptionsvermögen im Bereich der UV-B-Strahlung mit scharfer Bandenstruktur und hohen Lichtschutzfaktoren aus.The preparations according to the invention are distinguished by a particularly high absorption capacity in the area of UV-B radiation with a sharp band structure and high sun protection factors.
Insbesondere der hohe Lichtschutzfaktor der Zubereitungen, der bereits bei niedrigen Konzentrationen an UV-absorbierenden Wirkstoffen gemessen wurde, war überraschend.In particular, the high sun protection factor of the preparations, which was measured even at low concentrations of UV-absorbing active ingredients, was surprising.
So liegt der Lichtschutzfaktor der kosmetischen oder dermatologischen Formulierungen im Bereich größer 14, bevorzugt im Bereich größer 25. Entsprechende Werte lassen sich beispielsweise mittels einer Lichtschutzemulsion mit einem Gehalt an Uvinul T150 von 3 Gew.-%, Uvinul® A Plus von 2 Gew.-% und einer Konzentration an Zinkoxid und/oder Titandioxid von 4 Gew.-% erzielen. Es ist aber auch möglich, die oben genannten Lichtschutzwerte durch Variation der Einsatzmengen an Uvinul® T150 der Formel I (im Bereich von 0,1 bis 10 Gew.-%), Uvinul® A Plus der Formel II (im Bereich von 0,1 bis 10 Gew.-%) und Zinkoxid und/oder Titandioxid (im Bereich von 0,1 bis 15 Gew.-%) zu erzielen. Wie aus Tabelle 2 zu sehen ist, zeigt die Kombination aus Uvinul® T150, Uvinul® A Plus und Zinkoxid (Emulsion A) bezüglich des Lichtschutzfaktors synergistische Effekte, die deutlich über die additiven Effekte der jeweiligen Einzelkomponenten hinausgehen.The sun protection factor of the cosmetic or dermatological formulations is in the range greater than 14, preferably in the range greater than 25. Corresponding values can be achieved, for example, by means of a light protection emulsion with a Uvinul T150 content of 3% by weight, Uvinul® A Plus of 2% by weight. % and a concentration of zinc oxide and / or titanium dioxide of 4% by weight. However, it is also possible for the light stabilizers above values by varying the amounts of Uvinul ® T150 of the formula I (in the range of 0.1 to 10 wt .-%), Uvinul A Plus ® of formula II (in the range of 0.1 to 10 wt .-%) and zinc oxide and / or titanium dioxide (in the range of 0.1 to 15 wt .-%) to achieve. As can be seen from Table 2, the combination of Uvinul® T150, Uvinul® ® A Plus and zinc oxide (Emulsion A) with respect to the sun protection factor shows synergistic effects which go far beyond the additive effects of the respective single components.
Tabelle 2Table 2
Figure imgf000010_0001
1J Herstellung, siehe Beispiele; 2> Bestimmt nach der Colipa Methode, beschrieben in Parfuem. Kosmet. (1994), 75(12), 856
Figure imgf000010_0001
1J production, see examples; 2 > Determined according to the Colipa method, described in perfume. Kosmet. (1994), 75 (12), 856
Ein weiterer Vorteil der erfindungsgemäßen Zubereitungen liegt in der Tatsache, daß bereits mit sehr geringen Mengen an Uvinul T 150 (0,1 bis 10 Gew.-%, bevorzugt 1 bis 6 Gew.-%, besonders bevorzugt 2 bis 6 Gew.-%, ganz besonders bevorzugt 2 bis 4 Gew.-%), Uvinul® A Plus (0,1 bis 10 Gew.-%, bevorzugt 1 bis 6 Gew.-%, besonders bevorzugt 1 bis 5 Gew.-%, ganz besonders bevorzugt 1 bis 3 Gew.-%) und Zinkoxid bzw. Titandioxid (0,1 bis 15 Gew.-%, bevorzugt 1 bis 8 Gew.-%, besonders bevorzugt 2 bis 6 Gew.-%) schon zufriedenstellende Lichtschutzwerte erhalten werden können.Another advantage of the preparations according to the invention lies in the fact that even with very small amounts of Uvinul T 150 (0.1 to 10% by weight, preferably 1 to 6% by weight, particularly preferably 2 to 6% by weight , very particularly preferably 2 to 4 wt .-%), Uvinul A Plus ® (0.1 to 10 wt .-%, preferably 1 to 6 wt .-%, particularly preferably 1 to 5 wt .-%, most preferably 1 to 3% by weight) and zinc oxide or titanium dioxide (0.1 to 15% by weight, preferably 1 to 8% by weight, particularly preferably 2 to 6% by weight) already satisfactory sun protection values can be obtained.
Die folgenden Beispiele sollen die vorliegende Erfindung verdeutlichen, ohne sie einzuschränken.The following examples are intended to illustrate the present invention without restricting it.
Allgemeine Vorschrift zur Herstellung der erfindungsgemäßen Zubereitungen als EmulsionenGeneral instructions for the preparation of the preparations according to the invention as emulsions
Die jeweiligen Phasen A und C wurden getrennt auf ca. 85°C erwärmt. Anschließend wurde Phase C und das Metalloxid unter Homo- genisieren in Phase A eingerührt. Nach kurzem Nachhomogenisieren wurde die Emulsion unter Rühren auf Raumtemperatur abgekühlt und abgefüllt. Alle Mengenangaben sind auf das Gesamtgewicht der Zubereitungen bezogen.The respective phases A and C were heated separately to approx. 85 ° C. Phase C and the metal oxide were then stirred into phase A with homogenization. After a brief post-homogenization, the emulsion was cooled to room temperature with stirring and bottled. All quantities are based on the total weight of the preparations.
Beispiel 1example 1
Emulsion A, enthaltend 3 Gew.-% Uvinul® T150, 2 Gew.-% Uvinul® A Plus und 4 Gew.-% Zinkoxid (Lichtschutzfaktor 29)Emulsion A, containing 3% by weight Uvinul ® T150, 2% by weight Uvinul ® A Plus and 4% by weight zinc oxide (sun protection factor 29)
Figure imgf000011_0001
Vergleichsbeispiel 1
Figure imgf000011_0001
Comparative Example 1
Emulsion B, enthaltend 3 Gew.-% Uvinul® T150 und 2 Gew.-% Uvinul0 A Plus (Lichtschutzfaktor 17)Emulsion B, containing 3% by weight Uvinul ® T150 and 2% by weight Uvinul 0 A Plus (sun protection factor 17)
Figure imgf000011_0002
Figure imgf000012_0001
Vergleichsbeispiel 2
Figure imgf000011_0002
Figure imgf000012_0001
Comparative Example 2
Emulsion C, enthaltend 3 Gew. -% Uvinul® T150 und 4 Gew.-% Zink- oxid (Lichtschutzfaktor 23)Emulsion C, containing 3% by weight of Uvinul ® T150 and 4% by weight of zinc oxide (sun protection factor 23)
Figure imgf000012_0002
Vergleichsbeispiel 3
Figure imgf000012_0002
Comparative Example 3
Emulsion D, enthaltend 3 Gew.-% Uvinul® T150 und 4 Gew.-% Uvinul® Ti02 (Lichtschutzfaktor 23)Emulsion D, containing 3% by weight of Uvinul ® T150 and 4% by weight of Uvinul ® Ti0 2 (sun protection factor 23)
Figure imgf000013_0001
Figure imgf000013_0001
Vergleichsbeispiel 4Comparative Example 4
Emulsion E, enthaltend 3 Gew.-% Uvinul® T150 (Lichtschutzfaktor 9)Emulsion E, containing 3% by weight Uvinul ® T150 (sun protection factor 9)
Figure imgf000013_0002
Figure imgf000014_0001
Vergleichsbeispiel 5
Figure imgf000013_0002
Figure imgf000014_0001
Comparative Example 5
Emulsion F, enthaltend 4 Gew.-% Zink Oxid (Lichtschutzfaktor 4)Emulsion F, containing 4% by weight zinc oxide (sun protection factor 4)
Figure imgf000014_0002
Vergleichsbeispiel 6
Figure imgf000014_0002
Comparative Example 6
Emulsion G, enthaltend 4 Gew.-% Uvinul® Ti0 (Lichtschutzfaktor 6)Emulsion G, containing 4% by weight Uvinul ® Ti0 (sun protection factor 6)
Figure imgf000014_0003
Figure imgf000015_0001
Figure imgf000014_0003
Figure imgf000015_0001

Claims

Patentansprüche claims
1. Kosmetische oder dermatologische Zubereitungen, enthaltend a) 0,1 bis 10 Gew.-% 2, 4, 6-Trianilino-p- (carbo-2 λ -ethyl-he- xyl-1 '-oxi) -1, 3, 5-triazin der Formel I1. Cosmetic or dermatological preparations comprising a) 0.1 to 10 wt .-% of 2, 4, 6-trianilino-p- (carbo-2-ethyl-hexyl λ-1 '-oxi) -1, 3 , 5-triazine of the formula I.
Figure imgf000016_0001
b) 0 , 1 bis 10 Gew . -% N, N-Diethylcimino-hydroxybenzoyl-n-he- xylbenzoat der Formel II
Figure imgf000016_0001
b) 0.1 to 10 wt. % N, N-diethylcimino-hydroxybenzoyl-n-hexylbenzoate of the formula II
Figure imgf000016_0002
und c) 0,1 bis 15 Gew.-% Zinkoxid und/oder Titandioxid.
Figure imgf000016_0002
and c) 0.1 to 15% by weight of zinc oxide and / or titanium dioxide.
2. Kosmetische oder dermatologische Zubereitungen nach Anspruch 1, enthaltend a) 1 bis 6 Gew.-% der Verbindung I, b) 1 bis 6 Gew.-% der Verbindung II und c) 1 bis 8 Gew.-% Zinkoxid und/oder Titandioxid.2. Cosmetic or dermatological preparations according to claim 1, containing a) 1 to 6% by weight of compound I, b) 1 to 6% by weight of compound II and c) 1 to 8% by weight of zinc oxide and / or titanium dioxide.
3. Kosmetische oder dermatologische Zubereitungen nach einem der Ansprüche 1 oder 2, enthaltend a) 2 bis 6 Gew.-% der Verbindung I, b) 1 bis 5 Gew.-% der Verbindung II und c) 2 bis 6 Gew.-% Zinkoxid.3. Cosmetic or dermatological preparations according to one of claims 1 or 2, containing a) 2 to 6 wt .-% of compound I, b) 1 to 5% by weight of compound II and c) 2 to 6% by weight of zinc oxide.
4. Kosmetische oder dermatologische Zubereitungen nach einem der Ansprüche 1 bis 3 mit einem Lichtschutzfaktor > 14.4. Cosmetic or dermatological preparations according to one of claims 1 to 3 with a sun protection factor> 14.
5. Kosmetische oder dermatologische Zubereitungen nach einem der Ansprüche 1 bis 4 mit einem Lichtschutzfaktor > 25.5. Cosmetic or dermatological preparations according to one of claims 1 to 4 with a sun protection factor> 25.
6. Verwendung von kosmetischen oder dermatologischen Zubereitungen, definiert gemäß Anspruch 1, zum Schutz der menschlichen Haut oder menschlichen Haare gegen Sonnenstrahlen, allein oder zusammen mit an sich für kosmetische und dermatologische Zubereitungen bekannten, im UV-Bereich absorbierenden Verbindungen . 6. Use of cosmetic or dermatological preparations, defined according to claim 1, for the protection of human skin or human hair against sun rays, alone or together with compounds known per se for cosmetic and dermatological preparations, in the UV range absorbing compounds.
PCT/EP2005/001499 2004-02-17 2005-02-15 Cosmetic or dermatological preparations containing a mixture of a uv-a filter, a uv-b filter, and a metal oxide WO2005094769A1 (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008028665A1 (en) * 2008-06-09 2009-12-17 Beiersdorf Ag Cosmetic preparation, useful e.g. as light protection filter, make-up product in decorative cosmetics, skin care cream and day or night cream and as sunscreen, comprises titanium dioxide particle in a primary particle size distribution
CN107157789A (en) * 2016-02-29 2017-09-15 爱茉莉太平洋股份有限公司 Isolate harm ray make-up composition

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1310237A2 (en) * 2001-11-09 2003-05-14 Beiersdorf AG Cosmetic and dermatological sunscreen formulations comprising hydroxybenzophenones and acrylamide polymers
WO2003039506A2 (en) * 2001-11-09 2003-05-15 Beiersdorf Ag Cosmetic and dermatological light protection formulations with a content of hydroxybenzophenones and alkylnaphthalates
WO2003053395A1 (en) * 2001-12-20 2003-07-03 Beiersdorf Ag Cosmetic and dermatological light-protective formulations comprising water-soluble uv-filter substances and benzoxazole derivatives
WO2003082237A2 (en) * 2002-03-28 2003-10-09 Beiersdorf Ag Water proof cosmetic and dermatological sun protecting formulations containing acetylated stearic acid esters
WO2003082221A1 (en) * 2002-03-28 2003-10-09 Beiersdorf Ag Waterproof cosmetic and dermatological sun protecting formulations containing polyoxyethylene-polydodecylglycol-block polymers
DE10214054A1 (en) * 2002-03-28 2003-10-09 Beiersdorf Ag Oil-soluble or -dispersible alpha-olefin/maleic anhydride copolymers are used to increase the water-resistance and foaming of sunscreen compositions and O/W emulsions
EP1388338A1 (en) * 2002-08-07 2004-02-11 Beiersdorf AG Foaming sunscreen composition
WO2005025521A2 (en) * 2003-09-15 2005-03-24 Basf Aktiengesellschaft Powdered preparations containing a mixture of 2,4,6-trianilino-p-(carbo-2'-ethylhexyl-1'-oxi)-1,3,5-triazine and diethylamino-hydroxybenzoyl-hexyl-benzoate

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1310237A2 (en) * 2001-11-09 2003-05-14 Beiersdorf AG Cosmetic and dermatological sunscreen formulations comprising hydroxybenzophenones and acrylamide polymers
WO2003039506A2 (en) * 2001-11-09 2003-05-15 Beiersdorf Ag Cosmetic and dermatological light protection formulations with a content of hydroxybenzophenones and alkylnaphthalates
WO2003053395A1 (en) * 2001-12-20 2003-07-03 Beiersdorf Ag Cosmetic and dermatological light-protective formulations comprising water-soluble uv-filter substances and benzoxazole derivatives
WO2003082237A2 (en) * 2002-03-28 2003-10-09 Beiersdorf Ag Water proof cosmetic and dermatological sun protecting formulations containing acetylated stearic acid esters
WO2003082221A1 (en) * 2002-03-28 2003-10-09 Beiersdorf Ag Waterproof cosmetic and dermatological sun protecting formulations containing polyoxyethylene-polydodecylglycol-block polymers
DE10214054A1 (en) * 2002-03-28 2003-10-09 Beiersdorf Ag Oil-soluble or -dispersible alpha-olefin/maleic anhydride copolymers are used to increase the water-resistance and foaming of sunscreen compositions and O/W emulsions
EP1388338A1 (en) * 2002-08-07 2004-02-11 Beiersdorf AG Foaming sunscreen composition
WO2005025521A2 (en) * 2003-09-15 2005-03-24 Basf Aktiengesellschaft Powdered preparations containing a mixture of 2,4,6-trianilino-p-(carbo-2'-ethylhexyl-1'-oxi)-1,3,5-triazine and diethylamino-hydroxybenzoyl-hexyl-benzoate

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008028665A1 (en) * 2008-06-09 2009-12-17 Beiersdorf Ag Cosmetic preparation, useful e.g. as light protection filter, make-up product in decorative cosmetics, skin care cream and day or night cream and as sunscreen, comprises titanium dioxide particle in a primary particle size distribution
CN107157789A (en) * 2016-02-29 2017-09-15 爱茉莉太平洋股份有限公司 Isolate harm ray make-up composition

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