WO2005090387A3 - Derives de peptide d'histone h2a et analogues, et methodes d'utilisation - Google Patents
Derives de peptide d'histone h2a et analogues, et methodes d'utilisation Download PDFInfo
- Publication number
- WO2005090387A3 WO2005090387A3 PCT/IL2005/000328 IL2005000328W WO2005090387A3 WO 2005090387 A3 WO2005090387 A3 WO 2005090387A3 IL 2005000328 W IL2005000328 W IL 2005000328W WO 2005090387 A3 WO2005090387 A3 WO 2005090387A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- treating
- protecting against
- methods
- histone
- analogs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/527,162 US7528227B2 (en) | 2004-03-23 | 2006-09-25 | Histone H2A peptide derivatives and uses thereof |
US11/750,408 US7605132B2 (en) | 2001-08-29 | 2007-05-18 | Protective factors against inflammation, burns and noxious stimuli |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55533404P | 2004-03-23 | 2004-03-23 | |
US60/555,334 | 2004-03-23 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/527,162 Continuation-In-Part US7528227B2 (en) | 2001-08-29 | 2006-09-25 | Histone H2A peptide derivatives and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005090387A2 WO2005090387A2 (fr) | 2005-09-29 |
WO2005090387A3 true WO2005090387A3 (fr) | 2006-02-02 |
Family
ID=34964143
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IL2005/000328 WO2005090387A2 (fr) | 2001-08-29 | 2005-03-23 | Derives de peptide d'histone h2a et analogues, et methodes d'utilisation |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2005090387A2 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL1866328T3 (pl) | 2005-03-22 | 2011-05-31 | Rohto Pharma | Peptydy zwiększające wytwarzanie kolagenu lub kwasu hialuronowego |
WO2008010218A1 (fr) * | 2006-07-17 | 2008-01-24 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Peptides dérivés de l'histone h2a humaine et leurs procédés d'utilisation |
EP2558110B1 (fr) | 2010-04-11 | 2015-06-03 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Extrait et peptides dérivés du groupe oryza sativa japonica et leurs utilisations |
US9518107B2 (en) | 2010-08-31 | 2016-12-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | Pharmaceutical compositions containing polypeptides derived from α-1 antitrypsin and methods of use thereof |
EP2611459B1 (fr) | 2010-08-31 | 2019-12-11 | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. | Polypeptides dérivés d'alpha-1 antitrypsin pour l'utilisation dans le traitement de l'inflammation |
US10570174B2 (en) | 2015-02-08 | 2020-02-25 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Peptides for the treatment of malignant proliferative diseases |
CN106397575A (zh) * | 2016-10-20 | 2017-02-15 | 上海懿贝瑞生物医药科技有限公司 | 一种具有胞外组蛋白毒性抑制作用的多肽制备方法及用途 |
CN112745379A (zh) * | 2021-01-22 | 2021-05-04 | 浙江辉肽生命健康科技有限公司 | 具有氨基酸结构rdnkktriipr的生物活性肽及其制备方法和应用 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0489577A1 (fr) * | 1990-12-03 | 1992-06-10 | Celltech Limited | Dérivés peptidyliques |
WO1998009985A2 (fr) * | 1996-09-03 | 1998-03-12 | Yeda Research And Development Co. Ltd. | Peptides anti-inflammatoires et leurs utilisations |
WO2003017920A2 (fr) * | 2001-08-29 | 2003-03-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Facteurs de protection contre des inflammations, des brulures et des stimuli nocifs |
EP1297753A1 (fr) * | 2001-10-01 | 2003-04-02 | Societe Des Produits Nestle S.A. | Peptides pour l'utilisation comme flavour |
-
2005
- 2005-03-23 WO PCT/IL2005/000328 patent/WO2005090387A2/fr active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0489577A1 (fr) * | 1990-12-03 | 1992-06-10 | Celltech Limited | Dérivés peptidyliques |
WO1998009985A2 (fr) * | 1996-09-03 | 1998-03-12 | Yeda Research And Development Co. Ltd. | Peptides anti-inflammatoires et leurs utilisations |
WO2003017920A2 (fr) * | 2001-08-29 | 2003-03-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Facteurs de protection contre des inflammations, des brulures et des stimuli nocifs |
EP1297753A1 (fr) * | 2001-10-01 | 2003-04-02 | Societe Des Produits Nestle S.A. | Peptides pour l'utilisation comme flavour |
Also Published As
Publication number | Publication date |
---|---|
WO2005090387A2 (fr) | 2005-09-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2005090387A3 (fr) | Derives de peptide d'histone h2a et analogues, et methodes d'utilisation | |
RU2007131504A (ru) | Пептиды, обладающие агонистической активностью в отношении рецептора нейропептида-2-(y2r) | |
RS20050530A (en) | Binding agents which inhibit myostatin | |
UA100222C2 (uk) | Тканинозахисні пептиди і їх застосування | |
TR199800258T1 (xx) | Yeni opioid peptidler. | |
WO2014165607A3 (fr) | Formulations peptidiques cationiques aromatiques, compositions et procédés d'utilisation | |
WO2010005580A3 (fr) | Procédés et compositions de modulateurs à petites molécules de l’activité du facteur de croissance des hépatocytes (facteur de diffusion) | |
DE602007014210D1 (de) | Prophylaktisches/therapeutisches mittel für neurodegenerative erkrankungen | |
WO2007014253A3 (fr) | Methode permettant de traiter ou de prevenir la deterioration, les lesions ou les dommages tissulaires causes par l'insuffisance cardiaque congestive | |
WO2007096396A3 (fr) | Procédés de traitement de maladies auto-immunes ou démyélinisantes | |
EP2308837A3 (fr) | Dérivés d'acide hydroxamique substitués d'arylsulfonamido en tant qu'inhibiteurs de métalloprotéinases de matrice | |
WO2009047513A3 (fr) | Composé, utilisation et procédé | |
KR20170138547A (ko) | 자가 면역 및 염증성 질환의 치료 및/또는 예방을 위한 짧은 합성 펩타이드 | |
WO2004009625A3 (fr) | Peptides et derives de peptides destines au traitement des maladies liees a ?-synucleine | |
TW200501963A (en) | Pharmaceutical compositions comprising epinastine for the treatment of skin diseases | |
NO20062857L (no) | Farmasoytisk preparat omfattende et sink-hyaluronatkompleks for behandling av multippel sklerose | |
NO20060675L (no) | Forbedrede, rekombinante, humane interferon-beta-lb-polypeptider | |
CA2940751C (fr) | Utilisations d'un peptide d'angiotensine (1-7) pour le traitement retarde d'un accident vasculaire cerebral | |
RU2537560C2 (ru) | Тетрапептид и средство, обладающее церебропротекторной и антиамнестической активностями (варианты) | |
WO2010086867A3 (fr) | Peptides, compositions pharmaceutiques en contenant et leurs utilisations | |
US11879020B2 (en) | Cyclic peptidomimetic for the treatment of neurological disorders | |
GB2426706A (en) | Glycosaminoglycan peptides derived from connective tissues and use thereof in the prevention of arthritis and other degenerative medical conditions | |
BRPI0418017A (pt) | medicamento compreendendo inibidores de pentraxina ptx3 longa | |
WO2007139433A8 (fr) | Substance peptidique normalisant le métabolisme dans les tissus osseux et cartilagineux, composition pharmaceutique à base de ladite substance et procédé d'application afférent | |
WO2010112710A3 (fr) | Peptides anti-age activateurs du proteasome et compositions les contenant |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 11527162 Country of ref document: US |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWW | Wipo information: withdrawn in national office |
Country of ref document: DE |
|
WWP | Wipo information: published in national office |
Ref document number: 11527162 Country of ref document: US |
|
122 | Ep: pct application non-entry in european phase |