WO2005075984A1

WO2005075984A1 - Vessel for collecting excrement

Info

Publication number: WO2005075984A1
Application number: PCT/JP2005/001828
Authority: WO
Inventors: Makoto Fukasawa; Tetsubumi Kowaguchi; Katsunori Motojima; Noriyuki Suzuki
Original assignee: Dic Plastics, Inc.; Kyowa Medex Co., Ltd.
Priority date: 2004-02-09
Filing date: 2005-02-08
Publication date: 2005-08-18

Abstract

A vessel for collecting excrement, comprising a vessel body (1) for storing the excrement, an inner cover (2) fixed to the opening part of the vessel body (1), and an excrement collecting part (4) having an excrement collecting rod (30) for collecting the excrement and detachably fitted to the inner cover (2). The inner cover (2) further comprises a stocker tube part (12) in which the excrement collecting rod (30) is inserted, an insert hole (40) formed in the stocker tube part (12) and in which the excrement collecting rod (30)is inserted, and a plurality of ribs (42) formed in the stocker tube part (12) on the front side of the insert hole (40) in the excrement collecting rod inserting direction. The ribs (42) are formed so as to be extended along the longitudinal direction of the excrement collecting rod.

Description

Specification

Stool collection container

Technical field

The present invention relates to a container for collecting feces.

Background art

[0002] A stool collection container includes a stool collection part having a gripping part at one end and a stool collection rod formed at the other end, a container body into which the stool collection rod is inserted, Conventionally, an apparatus having an inner lid fitted into an opening of a container body has been used.

[0003] The inner lid is formed with an insertion port into which a stool collection rod is inserted. By inserting a stool collection stick through which the stool is attached, the excess stool is removed and the container is removed. It has the effect of keeping the amount of stool inserted into the body constant. In particular, when collecting feces for occult blood tests, etc., it is required to keep the amount of feces inserted into the container body as accurate as possible in order to improve the accuracy of quantitative analysis.

[0004] Techniques related to the present invention are disclosed, for example, in Patent Document 1 and Patent Document 2.

Patent Document 1: JP-A-10-300642

Patent Document 2: JP-A-10-300643

Disclosure of the invention

Problems to be solved by the invention

[0005] An object of the present invention is to provide a container for collecting stool that keeps the amount of stool inserted into the container body constant and accurate.

Means for solving the problem

The present invention relates to the following (1)-(6).

(1) A container body for accommodating a stool, an inner lid fixed to an opening of the container body, and a sampling device detachably attached to the inner lid having a stool collection rod for collecting stool. A toilet portion, wherein the inner lid has a cylindrical portion through which the feces collection rod is inserted, an insertion hole formed in the cylindrical portion, into which the feces collection rod is inserted, and an insertion hole inside the cylindrical portion. A plurality of ribs formed on the near side in the insertion direction of the stool bar, wherein the ribs extend along the longitudinal direction of the stool bar. A stool collection container having a shape.

[0007] (2) The container for fecal collection according to (1), wherein a taper is provided in the cylindrical portion, on the front side in the insertion direction of the fecal collection rod of the insertion hole, the diameter of which decreases toward the insertion hole. A container for stool which has a surface formed and said ribs are formed on the taper surface.

(3) The container for collecting feces according to the above (1) or (2), wherein the ribs are radially arranged around the insertion hole.

(4) The container for collecting feces according to any one of (1) to (3) above, wherein at least a part of the rib has an inner peripheral side end at which the feces collection rod is inserted. A stool container having an inner peripheral projection protruding toward the front side of the container.

(5) The container for collecting feces according to any one of (1) to (4), wherein at least a part of the rib has a concave portion on an end face on a front side in the inserting direction of the feces sampling rod. Formed valley for collecting feces.

[0008] (6) The stool collection container according to any one of (1) to (5) above, wherein a stool storage recess is formed at a tip of the stool collection rod.

The container for stool collection of the present invention has a container body for accommodating stool, an inner lid fixed to the opening of the container body, and a stool collection rod for collecting stool, which is attached to and detached from the inner lid. A stool collection part attached so as to be capable of being mounted, wherein the inner lid includes a cylindrical part through which the stool collection rod is inserted, an insertion hole formed in the cylindrical part, into which the stool collection rod is inserted, and A plurality of ribs are formed in the cylindrical portion on the front side of the insertion hole in the direction of inserting the stool bar, and the ribs have a shape extending along the longitudinal direction of the stool bar.

[0009] In the above-mentioned container for faeces, a tapered surface which is reduced in diameter toward the insertion hole is formed in the cylindrical portion on the front side of the insertion hole in the feces sampling rod insertion direction. A rib may be formed.

In the above feces collection container, the ribs may be arranged radially around the insertion hole.

In the above-mentioned container for faeces, at least a part of the rib may be formed with an inner-peripheral-side protrusion protruding toward the near side in the feces-collecting rod insertion direction at an inner peripheral end. In the above-mentioned feces collection container, a recess may be formed in at least a part of the rib on an end surface on the near side in the feces sampling rod insertion direction.

In the above-mentioned container for stool collection, a stool accommodation recess may be formed at the tip of the stool collection rod.

The invention's effect

[0010] In order to use the stool collection container, the stool collection unit is removed from the inner lid force, and stool is collected using the stool collection bar of the stool collection unit. The stool may adhere excessively to the tip or the outer peripheral surface of the stool collection rod. When the stool collection rod with excessive stool is inserted through the tube section of the inner lid, the tip of the stool collection rod first contacts the ribs, and the excess stool is dropped off by these ribs. The excess stool that has been dropped is pushed into the inter-rib groove between the ribs as the stool sampling rod is inserted into the container body, and is retained by the inter-rib groove. Therefore, in the container for stool collection of the present invention, excess stool can be reduced by the force of the stool collection rod, and the amount of stool stored in the container body can be kept constant and accurate.

Brief Description of Drawings

FIG. 1 is a partially cutaway front view showing a first embodiment of a stool collection container of the present invention.

FIG. 2 is a partially cutaway side view of the first embodiment.

FIG. 3 is a cross-sectional view showing a middle lid of the first embodiment.

FIG. 4 is a cross-sectional view taken along line IV-IV in FIG.

FIG. 5 is an enlarged cross-sectional view showing a lower end portion of a cylindrical portion according to the first embodiment.

FIG. 6A is a front view showing the tip of the stool collection rod.

FIG. 6B is a sectional view taken along line VIB-VIB in FIG. 6A.

FIG. 7 is an enlarged cross-sectional view showing the effect of the first embodiment.

FIG. 8 is a cross-sectional view showing a shape of a rib in a second embodiment of the present invention.

FIG. 9 is a longitudinal sectional view showing a shape of a rib according to a second embodiment.

FIG. 10 is a cross-sectional view showing a shape of a rib according to a third embodiment of the present invention.

FIG. 11 is a longitudinal sectional view showing a shape of a rib according to a third embodiment.

FIG. 12 is a cross-sectional view showing a shape of a rib according to a fourth embodiment of the present invention. FIG. 13 is a longitudinal sectional view showing a shape of a rib according to a fourth embodiment.

FIG. 14 is a cross-sectional view showing a shape of a rib according to a fifth embodiment of the present invention.

FIG. 15 is a longitudinal sectional view showing a shape of a rib according to a fifth embodiment.

FIG. 16 is a longitudinal sectional view showing a shape of a rib according to a sixth embodiment.

FIG. 17 is a longitudinal sectional view showing a shape of a rib according to a seventh embodiment.

Explanation of symbols

1 Container body

2 Inner lid

4 Sampling department

6 bottom

8 Thin part

10 Flange

12 cylinder

14 Upper end fitting

14A ridge

16 Support

18 Engagement part

20 Flange

20A ridge

22 Outer lid

24 gripper

26 Bar

28 Inner lid mating part

30 Stool collection bar

32 flight accommodation recess

40 揷 Inlet

44 Theno surface 46 Groove between ribs

48 Theno

Flight B

50 recess

52 Inner circumference projection

54 Inner circumference protrusion

BEST MODE FOR CARRYING OUT THE INVENTION

[0013] The stool collection container of the present invention includes a container body for storing stool, an inner lid fixed to an opening of the container body, and a stool collection rod for collecting stool. And a stool section detachably attached to the lid. The inner lid includes a tubular portion through which the stool collection rod is inserted, an insertion hole formed in the cylindrical portion, into which the stool collection rod is inserted, and a front side of the insertion hole inside the tubular portion in the direction of insertion of the stool collection rod. And a plurality of ribs formed on the side. The rib has a shape extending along the longitudinal direction of the stool bar.

[0014] In the cylindrical portion, a tapered surface that is reduced in diameter toward the insertion hole is formed on the front side of the insertion hole in the feces sampling rod insertion direction, and the rib is formed on the tapered surface. Well. The surface on which the ribs are formed is not limited to a tapered surface (conical surface), and may be a cylindrical surface or a curved surface.

[0015] The ribs may be arranged radially around the insertion hole. In this case, the intervals between the ribs in the circumferential direction may be equal, or a wide and narrow difference may be provided partially.

At least a portion of the rib may have an inner peripheral end that projects toward the near side in the insertion direction of the feces sampling rod. In this case, the effect of removing excess stool adhering to the stool collection rod by the inner peripheral side projection can be enhanced.

[0016] At least a part of the rib may be formed with a concave portion at an end face on the near side in the inserting direction of the feces sampling rod. In this case, a part of the excess stool enters the recess, and the wiping effect can be enhanced.

A stool storage recess may be formed at the tip of the stool collection rod. In this case, the excess stool protruding from the stool accommodation recess by the rib can be removed. Hereinafter, a preferred embodiment of a container for collecting stool according to the present invention will be described with reference to the drawings. However, the present invention is not limited to the following embodiments. For example, the components of each embodiment may be appropriately combined with each other, or another known configuration may be added.

FIG. 1 to FIG. 7 show a first embodiment of a feces collection container of the present invention. As shown in FIGS. 1 and 2, the container for collecting stool includes a container body 1 for storing stool, an inner lid 2 fixed to an opening of the container body 1, and a container for collecting stool. It has a stool collection part 4 having a stool collection rod 30 and detachably attached to the inner lid 2. The container body 1, the inner lid 2, and the stool section 4 are each integrally formed of plastic, metal, or the like. It may be made of the same material! Or may be made of different materials.

The container body 1 of this embodiment is an elongated container having a rectangular cross section, one end of which is an opening, and the other end of which is a closed bottom 6. In the center of the bottom part 6, a thin part 8 is formed. At the time of analyzing the stool, the liquid inside the container body 1 can be efficiently collected by piercing the injection needle or the like from the thin portion 8. Suction with a suction needle such as a syringe needle may be performed manually or automatically using an automatic measuring instrument! When using an automatic measuring instrument, set the container body 1 upside down on the automatic measuring instrument, lower the suction needle of the automatic measuring instrument to penetrate the thin-walled part 8, and suck the contents through the suction needle. The necessary measurements can be made in an automatic measuring instrument. At the upper end of the container body 1, a flange portion 10 is formed over the entire circumference. However, the shape of the container body 1 is not limited to the above shape, and any changes are possible.

[0020] The inner lid 2 includes a cylindrical stocker tube portion 12 through which the feces sampling rod 30 is inserted, a pair of engaging portions 18 that engage with the open end of the container body 1, and a flange portion 10 of the container body 1. A flange portion 20 joined to the stool by heat welding or an adhesive, a support portion 16 for supporting an outer lid portion 22 of the stool collection portion 4 described later, and a middle lid fitting portion 28 of the stool collection portion 4. And an upper end fitting portion 14 that fits. As shown in FIG. 3, an annular ridge 14A is formed on the inner peripheral surface of the upper end fitting portion 14 over the entire circumference. When the upper end fitting portion 14 is fitted into the inner lid fitting portion 28, the ridge 14A fits into an annular groove (not shown) formed on the outer periphery of the inner lid fitting portion 28 and is taken. Prevent unnecessary dropping of the toilet 4. [0021] On the lower surface of the flange portion 20, a ridge 20A is formed over the entire circumference for melting during heating and welding to increase the bonding force to the flange portion 10. When the flange portion 20 and the flange portion 10 are bonded with an adhesive or the like, the ridge 20A is unnecessary.

[0022] The inner diameter of the stocker tube portion 12 is slightly narrowed at the lower end side and larger at the upper end side so that the feces collection rod 30 can be easily inserted. At the lower end of the stocker tube portion 12, a circular insertion hole 40 is formed coaxially with the center axis of the stocker tube portion 12. The inner diameter of the insertion hole 40 is slightly larger than the outer diameter of the feces sampling rod 30. The inner diameter of the inlet hole 40 is not limited, but from the viewpoint of the effect of dropping stool, it is 1.01 to 1.1 times the outer diameter of the stool collection rod 30. 1. It is 05 times.

As shown in FIG. 4 and FIG. 5, in the stocker tube portion 12, the front side (upper side in FIG. 3) of the insertion hole 40 in the feces collection rod insertion direction is directed toward the insertion hole 40. A conical tapered surface 44 whose inner diameter is narrowed is formed. A plurality of ribs 42 are formed on the tapered surface 44 so that the force of the tapered surface 44 also rises vertically, and the central axial force of the stocker cylinder 12 is also radial.

[0024] The rib 42 of this embodiment has a shape extending in the longitudinal direction of the stool collection rod 30, that is, the longitudinal direction of the stocker cylinder 12. In this embodiment, each rib 42 has a right-angled triangular shape. The surface of the rib 42 that faces the center axis direction of the stocker tube portion 12 substantially matches the virtual surface that extends the inner peripheral surface of the insertion hole 40. As a result, when the stool collection rod 30 passes through the region surrounded by the ribs 42, excess stool is dropped off from the stool collection rod 30 at the upper end edge of each rib 42.

Although not shown, in the present invention, a configuration may be employed in which the surface of the upper end side of the rib 42 that faces the central axis of the stocker cylinder 12 is inclined so as to approach the central axis of the stocker cylinder 12. Conversely, a configuration may be adopted in which the central axial force of the stocker tube portion 12 is inclined so as to move away.

[0026] The ribs 42 of this embodiment are arranged at intervals of 60 ° around the central axis of the stocker tube portion 12, and the total number of the ribs 42 is six. However, the present invention is not limited to this configuration, and the total number of the ribs 42 may be appropriately changed according to the outer diameter of the feces collection rod 30. For example, two ribs 42 may be formed 180 ° apart from each other, three ribs 42 may be formed 120 ° apart, or four ribs may be formed 90 ° apart. 5 or 72 ° apart, 51.4 . It is also possible to use 7 at a distance, 8 at 45 °, 9 at 40 °, and 10 at 36 °. The same applies to 11 or more. The circumferential width (opening width) of the inter-rib groove 46 formed between the adjacent ribs 42 may be constant, but may be irregular.

In the present invention, the preferred number of ribs 42 is, for example, 3 to 20, and 6 to 12 is particularly preferred. This is because, even if the interval between the ribs 42 is too large or too narrow, the effect of retaining the stool by the inter-rib groove 46 is reduced.

The thickness of the rib 42 (the thickness in the circumferential direction around the central axis of the stocker cylinder 12) is not limited, and is preferably 1 to 15 ° in 1S circumferential angle. The total thickness of all the ribs 42 is not limited, and is appropriately determined according to the outer diameter of the feces sampling rod 30. If it is too small, the effect of removing the flight by the ribs 42 is reduced, and if it is too large, the effect of retaining the flights by the inter-rib grooves 46 is weakened.

In this embodiment, the upper end surface of the rib 42 is perpendicular to the central axis of the stocker cylinder 12. However, the upper end surface may be inclined so as to be higher toward the outer peripheral side or higher toward the inner peripheral side. In this embodiment, the edges around the ribs 42 are not chamfered, but may be chamfered (corner chamfers, curved chamfers) if necessary.

In this embodiment, the generatrix angle of the cross section of the tapered surface 44 is not limited, but is preferably 15-60 ° with respect to the central axis of the cylindrical portion 12 of the stocker, and more preferably 30-55 °. If it is too small, the inter-rib groove 46 becomes shallow and the effect of retaining stool is diminished. Fine stripe-shaped irregularities extending in the circumferential direction may be formed on the tapered surface 44 to further enhance the effect of retaining stool inside the inter-rib groove 46.

[0029] The stool collection unit 4 is formed coaxially with the outer lid portion 22 that covers the support portion 16 of the inner lid 2, a cylindrical grip portion 24 that extends upward from the outer lid portion 22, and the grip portion 24. A grip portion 24 having a rod portion 26, an inner lid fitting portion 28 to which the upper end fitting portion 14 of the inner lid 2 is fixed, and a cylindrical stool collection rod 30 extending downward is gripped on an outer peripheral surface of the grip portion 24. Grooves, ridges, dimples, etc. may be formed for ease of use.

[0030] The outer lid portion 22 enhances the fitting force between the stool collection portion 4 and the inner lid 2, and when the stool collection rod 30 is inserted into the stocker tube portion 12, a stool is formed inside the upper end fitting portion 14. Even if it adheres, it obscures it, It also has the role of keeping the aesthetic appearance. From this point of view, the stool section 4 may be formed of an opaque plastic.

[0031] The distal end of the stool collection rod 30 is formed in a hemispherical shape as shown in Fig. 6A. Four stool storage recesses 32 are formed at a distance from the distal end, spaced apart from each other. As shown in FIG. 6B, the stool storage recess 32 is a recess having a C-shaped cross section. By rubbing the tip of the stool collection rod 30 against the stool, a part of the stool is filled in the stool storage recess 32 and collected. Is performed. The lower two pieces and the upper two pieces of the feces accommodating recess 32 are formed at positions separated from each other by 180 °, but the positional relationship may be appropriately changed. Instead of the C-shaped stool storage recess 32, a simple annular groove may be formed as a stool storage recess at the tip of the stool collection rod 30, or a plurality of dimples may be formed at intervals from each other. Is also good.

To assemble the container for feces collection, first, a liquid such as a reagent solution is put into the container body 1, the inner lid 2 is fitted into the opening of the container body 1, and the flange portions 10 and 20 are attached. Heat welding is performed by a method such as high frequency induction heating. The reagent solution is a solution for dissolving and storing the collected stool. At this time, the ridge 20A melts and exhibits an adhesive action. The stool collection part 4 is attached to the inner lid 2, and the stool collection rod 30 is inserted into the container body 1 through the insertion hole 40 of the stocker tube part 12, and is packaged and shipped.

The liquid is not particularly limited as long as it dissolves the collected stool and stably preserves the stool until the measurement of hemoglobin in the stool, but a liquid containing a preservative or antibiotic is more preferable. Liquids containing a buffer, an organic acid, a saccharide, a protein, a ferrocyanide conjugate, a chelating agent, a salt, a protease inhibitor and the like, depending on the type of the solvent.

[0033] Examples of the preservative include tylomesal, hexidyl hexidyl, azirido, and the like. Examples of the azhi-dani include lithium azide, sodium azide, potassium azide and ammonium azide.

The concentration of the preservative is not particularly limited, but 0.01-5 wZv% is preferred. 0.05-1. Ow Zv% is more preferred.

[0034] Antibiotics include, for example, j8-ratatum antibiotics, tetracycline antibiotics, macrolide antibiotics, aminoglycoside antibiotics, nucleoside antibiotics, ansamicin antibiotics, polypeptide antibiotics, Other antibiotics and the like, Noglycoside antibiotics are preferred.

[0035] Examples of the β-latatam antibiotics include penicillins, cephalosporins, chenamycin, sulfazecin and the like. Examples of penicillins include penicillin G, penicillin II, penicillin 0, penicillin V, and the like. Examples of the cephalosporins include cephamycin Α, cephamycin Β, cephamycin C, cephalosporin, cephalotin, cephalo-pam, cephalexin, cephaladin, hetasporin, cephapirin, and oral caracarbef.

[0036] Examples of the tetracycline antibiotics include minocycline, tetracycline, no, idoxytetracycline, chronocycline, terramycin, nitrocycline, amycycline, anthracycline, metacycline, deoxycycline, glycocycline, and anhydrotetracycline. And the like.

[0037] Examples of macrolide antibiotics include acetilsviramycin, erythromycin, biclomycin, pimaricin, resensomycin, amphotericin Β, candicine Α, and candicine Β.

[0038] Examples of aminoglycoside antibiotics include streptomycin, streptomycin, streptomycin with dehydride, oxystreptomycin, kanamycin, kasugamycin, gentamicin, gentamicin C, lincomycin, bleomycin, mannoside hydroxy streptomycin, and the like.

Examples of the nucleoside antibiotics include polyoxin A, polyoxin B, polyoxin, polyxin D, polyoxin E, polyoxin F, polyoxin G, polyoxin H, polyoxin J, polyoxin K, polyoxin L, polyoxin M, Bbenoresidin, folmycin B, blasticidin S and the like.

[0040] Examples of the ansamycin antibiotic include ansamycin, rifamycin, rifamycin B, rifamycin L, rifamycin S, rifamycin V, rifamycin Y, rifampicin and the like.

Examples of polypeptide antibiotics include polymyxin, gramycin Α, gramycin Β, gramycin C, piomycin, nocitracin, actinomycin, tyrosidine A, tyrosidine B, tyrosidine C, tyrosidine D, tyrosidine S, staphyramycin, and the like. Is mentioned The

[0042] Other antibiotics include, for example, cycloheximide, cycloserine, sarcomycin A, spectinomycin, chloramphen-chol, mitomycin, fumagillin, monensin, pyrrole-trin, fofonomycin and the like.

[0043] The above antibiotics may form salts. Salts include, for example, acid addition salts (hydrochloride, sulfate, phosphate, acetate, fumarate, oxalate, tartrate, etc.), ammonium salts, organic amine addition salts (triethylamine salts). Etc.), metal salts (lithium salt, sodium salt, potassium salt, magnesium salt, calcium salt, etc.).

[0044] Antibiotics can be used alone or in combination of two or more. 10-100, OOOkU / L power is preferable, 100-100,000kU / L is more preferable! / ヽ.

[0045] Examples of the buffer include a phosphate buffer, a carbonate buffer, an ammonia buffer, an acetate buffer, a lactate buffer, a citrate buffer, a tartrate buffer, and 2-amino-2- (hydroxymethyl) buffer. —1,3 propanediol, 2 morpholinoethanesulfonic acid, piperazine 1,4-bis (2-ethanesulfonic acid), N— (2-acetoamide) —2-aminoethanesulfonic acid, N, N bis (2-hydroxyethyl) -2-aminoethanesulfonic acid, bis (2-hydroxyethyl) iminotris (hydroxymethyl) methane, 3- [bis (2-hydroxyethyl) amino] -2-hydroxypropanesulfonic acid 2- [4- (2-hydroxyethyl) -1-piperazyl] ethanesulfonate, 2- [4- (2-hydroxyethyl) -1-piperazul] -p-pansulfonate, 2-hydroxy 3- [4- (2-hydroxyethyl) -1-piperajur] propanesulfonate, 3-morpholinopropanesulfonate, 2-hydroxy-3-morpholinopropanesulfonate, piperazine 1,4bis ( 2-hydroxy-3-propanesulfonic acid), N-tris (hydroxymethyl) methyl-3-aminopropanesulfonic acid, 2-hydroxy-N-tris (hydroxymethyl) methyl-3-aminopropanesulfonic acid, tris (hydroxymethyl) Methyl 2-aminoethanesulfonic acid, N- (2-acetamido) iminoniacetic acid, N, N bis (2-hydroxyethyl) glycine, N- [tris (hydroxymethyl) methyl] glycine, N-cyclohexyl-3 —Aminopropanesulfonic acid, N-cyclohexyl-2-aminoethanesulfonic acid, etc. .

[0046] The concentration of the buffer is not particularly limited. For example, 0.001-ImolZL is preferred. One lOOmmolZL is more preferred 0.1-50 mmol ZL is particularly preferred. The pH of the buffer is not particularly limited. For example, the pH is preferably 5.0 to 9.0, the pH is more preferably 6.0 to 8.0, and the pH 6.5 to 7.5 is particularly preferable! / ヽ.

[0047] Examples of the organic acid include malic acid or a salt thereof, succinic acid or a salt thereof, fumaric acid or a salt thereof, glycolic acid or a salt thereof, 2-ketoglutaric acid or a salt thereof, isoquenic acid or a salt thereof, lactic acid or a salt thereof. Examples thereof include pyruvate or its salt, uric acid or its salt, oxa mouth acetic acid or its salt, and the like. Examples of the salt include an ammonium salt, a sodium salt, a potassium salt, a calcium salt, a magnesium salt and the like.

[0048] The concentration of the organic acid is not particularly limited, but for example, 0.1-2, OOOmmoL / L is preferred, and 0.2-1 and OOOmmol / L power is more preferable, and 0.5-700mmoL / L power ^ Especially preferred! / ,. Preferably, the organic acid is present in a weight ratio of, for example, 0.04 to 150 million with respect to hemoglobin 1.

[0049] Examples of the saccharide include glucose, sucrose, maltose, cyclodextrins, fructose, sorbose, saccharose, ratatose, trenodulose, galataturonic acid, mannitol, D-darcosamine, mannose, cellobiose, glycidol, inositol and the like. No. Examples of cyclodextrins include α-cyclodextrin, 13-cyclodextrin, γ-cyclodextrin, hydroxypropyl α-cyclodextrin, hydroxypropyl β-cyclodextrin, hydroxypropyl γ-cyclodextrin, 13-cyclodextrin polymer, dimethyl- j8-cyclodextrin, 6-O-α maltosyl-a-cyclodextrin, 6-O-a maltosyl-β-cyclodextrin Mo-sulfated at-cyclodextrin, 2, 3, 6-tree Ο-methyl-j8-cyclodextrin, etc. Is mentioned. As these cyclodextrins, commercially available products (for example, manufactured by Japan Food Processing Co., Ltd.) can also be used.

[0050] The concentration of the saccharide is not particularly limited. For example, 0.01-lOOOOgZL is preferred.

OOgZL is more preferred. One 250 gZL is particularly preferred.

Examples of proteins include albumin, iron protein and the like.

[0051] Examples of albumin include serum albumin, ovalbumin, lactalbumin and the like, and serum albumin is preferable. Serum albumin includes, for example, human, The plasma power of mammals such as ma and those prepared according to a conventional method or commercially available products can be used. Suitable serum albumin includes, for example, human serum albumin (hereinafter abbreviated as BSA), human serum albumin, and the like. Serum containing albumin is also used.

[0052] The concentration of the albumin is not particularly limited, for example, 0. 0001- 5wZv% is preferred instrument 0. 0005- preferably from 3w / v ^_0/0 ^{force, 0. 01- 2w / v 0/} 0 forces especially Like! / ,.

Albumin can be used in a ratio of 0.001 to 50 million by weight of hemoglobin.

[0053] Examples of iron proteins include non-heme iron proteins and heme iron proteins. Examples of non-heme iron proteins include holotransferrin, apotransferrin, ratatoferrin, ferritin, hemosiderin, ferredoxin, oxygenase and the like. Heme iron proteins include, for example, non-human animal hemoglobin, pherytocytochrome C, myoglobin, peroxidase, catalase and the like.

The concentration of the iron protein is not particularly limited, but 1 OmgZL—100 gZL is preferred 100 mgZL—30 gZL is more preferred 11 lOgZL is particularly preferred.

[0054] Examples of the ferrocyanide include sodium ferrocyanide, rhodium ferrocyanide, 11 ferrose-ru 1-undecanthiol, 8 ferrose-ru 1 octanethiol, 6 ferrose-ru 1-hexanthiol), 11 —Ferose-l-decenyl-polyoxyethylene ether, 11-phenyl-trimethyl-l-dimethyl-decyl-ammonium-bromobromide and the like.

The concentration of the ferrocyan compound is not particularly limited. For example, 1 μmolZL—100 mmol ZL is preferred, and 10 111017 to 30111111017 is more preferred. MolZL—15 mMolZL is particularly preferred.

As the chelating agent, for example, ethylenediaminetetraacetic acid or a salt thereof, O, 0,1-bis (2-aminophenyl) ethylene glycol Ν, Ν, Ν ′, Ν, —tetraacetic acid or a salt thereof, trans 1, 2-diaminocyclohexane Ν, Ν, Ν ′, Ν, tetraacetic acid or a salt thereof, 1,3-diamino — 2-hydroxypropane Ν, Ν, Ν ′, Ν, tetraacetic acid or a salt thereof, diethylenetriamine Ν, Ν, Ν ', Ν ,, Ν ,, pentaacetic acid or its salt, ethylenediamine Ν, Ν'-diacetic acid or its salt, ethylenediamine Ν, Ν' bis (methylenephosphonic acid) or its salt , Ν — (2-Hydroxyethyl) ethylenediamine Ν, Ν ′, Ν, —triacetic acid or a salt thereof, ethylenediamine Ν, Ν ′, Ν ′, Ν, -tetrakis (methylenephosphonic acid) or a salt thereof, Ο, 0, —Bis (2-aminoethyl) ethylene glycol Ν, Ν, Ν ',,, Νtetraacetic acid or its salt, Ν, Ν'-bis (2-hydroxybenzyl) ethylenediamine-Ν, Ν'-diacetic acid or its salt Salt, 1,6-hexamethylenediamine Ν, Ν, Ν ', Ν, tetraacetic acid or a salt thereof, Ν— (2-hydroxyethyl) iminoniacetic acid or a salt thereof, imino-acetic acid or a salt thereof, 1,2-diaminopropane Ν, Ν, Ν ', Ν'-tetraacetic acid or a salt thereof, uritrioacetic acid or a salt thereof, -trilotripropionic acid or a salt thereof, nitrilotris (methylenephosphonic acid) or a salt thereof Salt, Ν, Ν, Ν ', Ν, -tetrakis 2-pyridylmethyl) Echirenjiamin or a salt thereof, triethylenetetramine Ν, Ν, Ν ', Ν'',Ν'",Ν"'sixteen acetate or Ru mentioned or salts thereof. Examples of the salt include an ammonium salt, a sodium salt, a potassium salt, a magnesium salt, a potassium salt and the like.

[0056] The chelating agent is used at an appropriate concentration according to the sample amount. The concentration of the chelating agent is 0.

01—100 mmol ZL is preferred 0.1—50 mmol ZL is more preferred.

[0057] Salts include, for example, sodium salt sodium, sodium sulfate, potassium salt sodium, potassium sulfate, magnesium chloride, magnesium sulfate, magnesium acetate, lithium chloride, lithium sulfate, salt sodium sulfate, ammonium sulfate. -Palm, magnesium nitrate, calcium nitrate, etc.

The concentration of the salt is not particularly limited, but is preferably 0.1 to 100 gZL, more preferably 50 gZL.

[0058] Examples of the protease inhibitor include Complete (trademark, manufactured by Roche), Antipapain dihide mouth chloride, aprotune, chymostatin, E-64, leupeptin, pefabloc (trademark, manufactured by Roche), pepstatin A , Phosphoramidon, antithrombin III, (4-amidinophenol) methanesulfur fluoride, calpain inhibitor 1, 3, 4-diclomouth isocoumarin, _α- macroglobulin, bestatin and the like.

Although the concentration of the protease inhibitor is not particularly limited, for example, 0.1 mg / z gZmL—preferably 10 mg ZmL 0.05 μg ZmL—lmgZmL is more preferable 0.1-100 μg / mL is particularly preferable . 0. 001— lmol / L

10— 100, OOOkU / L

0.1-2, OOOmmol / L

0. 001— lmol / L

10— 100, OOOkU / L

0.1-2, OOOmol / L

0. 01— lOOmmol / L

[0061] To use the stool collection container, grasp the gripping portion 24, pull out the stool collection portion 4 from the inner lid 2, rub the tip of the stool collection rod 30 on the surface of the stool, and place the stool in the stool storage recess 32. Embed At this time, excessive stool may adhere to the outer peripheral surface and the tip of the stool collection rod 30.

Next, the stool collection rod 30 is inserted along the stocker tube portion 12 of the inner lid 2, and the tip of the stool collection rod 30 is inserted into the container body 1 through the insertion hole 40. In this process, as shown in FIG. 7, the tip of the stool collection rod 30 hits the inner peripheral edge of a part of the rib 42, and the stool attached to the tip of the stool collection rod 30 is removed by the rib 42. Further, when the stool collection rod 30 passes between the ribs 42, the stool attached to the outer peripheral surface of the stool collection rod 30 is removed by the rib 42. The dropped stool is pushed into the inter-rib groove 46 between the ribs 42 as the stool bar 30 is inserted into the container body 1, and the stool bar 30 is adhered to the inner surface of the inter-rib groove 46 by frictional resistance. And is retained by the inter-rib groove 46. Accordingly, in this container for collecting stool, excess stool is dropped off from the stool collection rod 30 by the rib 42 and held in the groove 46 between the ribs, so that the stool is stored in the container body 1. The amount of stool can be fixed and accurately defined based on the volume of the stool storage recess 32. In particular, the above embodiment is effective for hard stool.

[0063] On the other hand, in the case where the rib 42 is formed on the tapered surface 44, the stool adhering to the tip or the outer peripheral surface of the stool collection rod 30 causes a gap between the stool collection rod 30 and the insertion hole 40 to be formed. It passes through and enters container body 1. It is also conceivable to form a step-like step extending in the circumferential direction on the tapered surface 44 instead of the rib 42, but in this case, the stool is inserted into the distal end of the stool collection stick 30 or the outer peripheral surface while sticking. Immediately after passing through the hole 40, the effect of removing particularly hard stool becomes poor compared to the first embodiment.

[0064] Second embodiment

8 and 9 show a second embodiment of the present invention. This embodiment has a new feature in that a concave portion 50 is formed on the upper end surface of the rib 42. Other configurations may be the same as in the first embodiment.

The planar shape of the concave portion 50 is rectangular in the illustrated example, but may be a circular, elliptical, triangular, or other suitable shape. The concave portion 50 may be formed on the entire upper surface of the rib 42.

According to this embodiment, since the stool force dropped from the stool collection rod 30 at the inner peripheral edge of the rib 42 is not only removed from the groove 46 between the S-ribs but also retained in the concave portion 50. In addition, the effect of dropping the stool can be further enhanced.

[0065] Third Embodiment

FIG. 10 and FIG. 11 show a third embodiment of the present invention. This embodiment has a new feature in that an inner peripheral projection 52 is formed on the inner peripheral side of the upper end surface of the rib 42 (closer to the central axis of the stocker cylinder 12). Other configurations may be the same as in the first embodiment. The shape of the inner peripheral side projection 52 is triangular in the illustrated example, but may be any shape such as rectangular or semicircular. The entire upper surface of the rib 42 may be an inclined surface that rises toward the inner peripheral side. According to this embodiment, since the excess stool can be dropped off from the stool collection rod 30 by the inner peripheral side projection 52 of the rib 42 and peeled off, the effect of reducing the amount of stool is very high.

[0066] Fourth Embodiment

FIG. 12 and FIG. 13 show a fourth embodiment of the present invention. In this embodiment, the rib 42 A new feature is that an inner peripheral side projection 52 is formed on the inner peripheral side of the upper end surface (the side closer to the center axis of the stocker cylinder 12), and a concave portion 50 is formed on the upper end surface of the rib 42. Other configurations may be the same as in the first embodiment. The shape of the inner peripheral side projection 52 and the concave portion 50 may be the same as in the second and third embodiments. According to this embodiment, the synergistic effect of the inner peripheral side projection 52 and the concave portion 50 further enhances the effect of reducing the amount of feces collected.

[0067] Fifth Embodiment

14 and 15 show a fifth embodiment of the present invention. This embodiment has a new feature in that an inner peripheral protrusion 54 having a rectangular parallelepiped shape is formed on the inner peripheral side of the upper end surface of the rib 42 (closer to the central axis of the stocker cylinder 12). Other configurations may be the same as in the first embodiment. According to this embodiment, the excess stool can be removed from the stool collection rod 30 by the inner peripheral side projection 54 of the rib 42 and peeled off, so that the stool can be effectively quantified.

[0068] Sixth embodiment

FIG. 16 shows a sixth embodiment of the present invention. In this embodiment, instead of forming the tapered surface 44, a step-shaped step portion 56 is formed, and the rib 42 is formed in the step portion 56. Other configurations may be the same as in the first embodiment. According to this embodiment, there is an advantage that the capacity of the inter-rib groove 46 is larger than in the case where the tapered surface 44 exists, and a relatively large amount of stool can be accommodated.

[0069] Seventh Embodiment

FIG. 17 shows a seventh embodiment of the present invention. This embodiment is characterized in that instead of forming the tapered surface 44, an inner surface forms a curved step 58, and the rib 42 is formed in the step 58. Other configurations may be the same as in the first embodiment. According to this embodiment, as in the sixth embodiment, there is an advantage that the capacity of the inter-rib groove 46 is larger than in the case where the tapered surface 44 exists, and a relatively large amount of flights can be accommodated.

Industrial applicability

[0070] According to the present invention, a stool collection container capable of enhancing the effect of removing excess stool attached to the stool collection rod and maintaining a constant and accurate amount of stool inserted into the container body. Is provided. The stool collection container of the present invention is useful for screening of colon cancer for screening.

Claims

The scope of the claims

[1] A container main body for accommodating stool, an inner lid fixed to an opening of the container main body, and a sampling detachably attached to the inner lid having a stool collection rod for collecting stool. The inner lid includes a tubular portion through which the stool bar is inserted, an insertion hole formed in the tubular portion, into which the stool bar is inserted, and a collection hole for the insertion hole in the tubular portion. A plurality of ribs formed on the near side in the toilet rod insertion direction,

The stool container having a shape in which the rib extends along a longitudinal direction of the stool bar.

[2] The container for feces collection according to claim 1, wherein a tapered surface which is reduced in diameter toward the insertion hole is formed in the cylindrical portion on the front side of the insertion hole in the direction of inserting the feces sampling rod. A container for faeces having the tape formed with the ribs.

[3] The container for stool collection according to claim 1 or 2, wherein the ribs are radially arranged around the insertion hole! Pulp collection container.

[4] The container for feces collection according to any one of claims 13 to 13, wherein at least a part of the rib protrudes toward the near side in the insertion direction of the feces sampling rod at an inner peripheral end. An inner circumference side projection that is formed!

[5] The container for feces according to any one of [14] to [14], wherein a recess is formed in at least a part of the rib on an end face on the near side in the insertion direction of the feces sampling rod. Stool collection container

[6] The stool collection container according to any one of claims 11 to 5, wherein a stool storage recess is formed at a tip of the stool collection rod.